New approach more than doubles stem cell edit | EurekAlert!
They destroy the RNA before it can make proteins - say, in a matter of a few hours - and, in doing so, destroy the gene editing ... The researchers also found that the modRNA could improve other gene editing techniques, such as base editing. Base editing can ... "Only 20% to 30% of the targeted cells will receive gene-editing DNA when using CRISPR. Delivery of RNA into cells can be more ... According to Lian, as more gene-editing labs improve gene editing efficiency and effectiveness, researchers will be able to ...
Intranasal CRISPR psychotropics | EurekAlert!
The vector delivers a guide RNA to neurons. The guide RNA binds to the target receptor gene, HTR2A, which is then cut at a ... A study in mice reports a CRISPR/Cas9 gene-editing delivery system, capable of bypassing the blood-brain-barrier and modulating ... Life sciences/Genetics/Molecular genetics/Genetic engineering/Genome engineering/Genome editing/CRISPRs ... GFP-positive neurons positively transfected with guide RNA were identified in most brain regions including the olfactory bulb ( ...
Scientists use lipid nanoparticles to precise | EurekAlert!
Scientists use lipid nanoparticles to precisely target gene editing to the liver Gene editing delivery method in mice suggests ... After a single injection of lipid nanoparticles packed with mRNA coding for CRISPR-Cas9 and a single-guide RNA targeting ... The genome editing technology CRISPR has emerged as a powerful new tool that can change the way we treat disease. The challenge ... "We just have to make sure we deliver the gene editing package specifically to the liver so as not to create unwanted side ...