RNA-catalysed nucleotide synthesis | Semantic Scholar
The RNA world hypothesis proposes that early life developed by making use of RNA molecules, rather than proteins, to catalyse ... RNA-based life must therefore have acquired the ability to synthesize RNA nucleotides from simpler and more readily available ... poses a challenge to the RNA world hypothesis. Here we report the application of in vitro selection to isolate RNA molecules ... The finding that RNA can catalyse this type of reaction, which is modelled after pyrimidine synthesis in contemporary ...