Ribosomal protein S6 - Wikipedia
Studies show that the p70 ribosomal protein S6 kinases (S6K1 and S6K2) and p90 ribosomal protein S6 kinases (RSK) both ... Ribosomal protein S6 (rpS6 or eS6) is a component of the 40S ribosomal subunit and is therefore involved in translation. Mouse ... Ruvinsky I, Meyuhas O (June 2006). "Ribosomal protein S6 phosphorylation: from protein synthesis to cell size". Trends in ... Ribosomal+Protein+S6 at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Overview of all the structural ...
Phosphorylation of the c-Fos transrepression domain by mitogen-activated protein kinase and 90-kDa ribosomal S6 kinase
... Proc ... We now provide evidence that two growth-regulated, nucleus- and cytoplasm-localized protein kinases, 90-kDa ribosomal S6 kinase ... RSK) and mitogen-activated protein kinase (MAP kinase), contribute to the serum-induced phosphorylation of c-Fos. The major ...
Phospho-S6 Ribosomal Protein (Ser240/244) (D68F8) XP® Rabbit mAb (Alexa Fluor® 488 Conjugate) | Cell Signaling Technology
Phospho-S6 Ribosomal Protein (Ser240/244) (D68F8) XP® Rabbit Monoclonal Antibody (Alexa Fluor® 488 Conjugate) (CST #5018) is ... Monoclonal Antibody for studying S6 Ribosomal Protein (Ser240/Ser244) phosphate. Cited in 15 publications. Validated for ... as well as ribosomal proteins and elongation factors necessary for translation (2,3). Important S6 ribosomal protein ... Phospho-S6 Ribosomal Protein (Ser240/244) (D68F8) XP® Rabbit mAb (Alexa Fluor® 488 Conjugate) detects endogenous levels of S6 ...
1244-P: The Protein Phosphatase PPm1k Regulates Ribosomal Protein S6 Phosphorylation in Beta Cells | Diabetes | American...
Phosphorylation of ribosomal protein S6 (RPS6) on ser235/236 and ser240/244 in the pancreatic beta cell increases cell size and ... 1244-P: The Protein Phosphatase PPm1k Regulates Ribosomal Protein S6 Phosphorylation in Beta Cells YANN DELEYE; YANN DELEYE ... The Protein Phosphatase PPm1k Regulates Ribosomal Protein S6 Phosphorylation in Beta Cells. Diabetes 1 June 2021; 70 ( ... Phosphorylation of ribosomal protein S6 (RPS6) on ser235/236 and ser240/244 in the pancreatic beta cell increases cell size and ...
Ribosomal Protein S6 Hypofunction in Postmortem Human Brain Links mTORC1-Dependent Signaling and Schizophrenia -...
Ribosomal Protein S6 Hypofunction in Postmortem Human Brain Links mTORC1-Dependent Signaling and Schizophrenia Authors: Ibarra- ... Ribosomal Protein S6 Hypofunction in Postmortem Human Brain Links mTORC1-Dependent Signaling and Schizophrenia Authors:. Ibarra ... Print Ribosomal Protein S6 Hypofunction in Postmortem Human Brain Links mTORC1-Dependent Signaling and Schizophrenia ... Ribosomal Protein S6 Hypofunction in Postmortem Human Brain Links mTORC1-Dependent Signaling and Schizophrenia ...
Human ribosomal protein S6 kinase B1 - SynPharm
Monoclonal Antibodies - S6 Ribosomal Protein Mouse Monoclonal Antibody
S6 Ribosomal Protein Mouse Monoclonal Antibody detects endogenous levels of S6 Ribosomal Protein protein.. ... The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with ... Western blot analysis of extracts on different cells, using S6 Ribosomal Protein Mouse Monoclonal Antibody (EAB21309) at 1:1000 ... Protein Agonists, Antagonists and Activators. Protein Inhibitors. Protein Substrates. Stains, Dyes and Fluorescent Reagents. ...
Ribosomal Protein S6 Kinases, 90-kDa | Profiles RNS
Ribosomal Protein S6 Kinases [D08.811.913.696.620.682.700.862]. *Ribosomal Protein S6 Kinases, 90-kDa [D08.811.913.696.620.682. ... A family of ribosomal protein S6 kinases that are structurally distinguished from RIBOSOMAL PROTEIN S6 KINASES, 70-KDA by their ... Ribosomal Protein S6 Kinases, 90-kDa*Ribosomal Protein S6 Kinases, 90-kDa ... "Ribosomal Protein S6 Kinases, 90-kDa" by people in UAMS Profiles by year, and whether "Ribosomal Protein S6 Kinases, 90-kDa" ...
Ribosomal protein S6 mRNA is a biomarker upregulated in multiple sclerosis, downregulated by interferon treatment, and affected...
TSC1 and TSC2 regulate cilia length and canonical Hedgehog signaling via different mechanisms | Cellular and Molecular Life...
... and 40S ribosomal protein S6 kinase 1 (S6K1) to promote protein synthesis [3, 4]. The phosphorylated form of 40S ribosome ... rabbit anti-total-S6 Ribosomal Protein (1:1000, Cell Signaling #2217), rabbit anti-TSC1 (1:500, Abcam #ab25882), rabbit anti- ... rabbit anti-phospho-S6 Ribosomal Protein (1:1000, Cell Signaling # 4858), rabbit anti-GAPDH (1:5000, Cell Signaling #2118), ... d Normalized LC3B-II protein levels for experiments shown in a before PI treatment. b-d Quantifications of LC3B-I/II protein ...
For cell development, mTOR stimulates the creation of proteins through downstream effectors S6K and ribosomal protein S6 ...
... mTOR stimulates the creation of proteins through downstream effectors S6K and ribosomal protein S6 (protein synthesis including ... mTOR stimulates the creation of proteins through downstream effectors S6K and ribosomal protein S6 (protein synthesis including ... mTOR stimulates the creation of proteins through downstream effectors S6K and ribosomal protein S6 (protein synthesis including ... mTOR stimulates the production of proteins through downstream effectors S6K and ribosomal protein Ruxolitinib sulfate S6 ( ...
RSK2 mediates muscle cell differentiation through regulation of NFAT3
RCSB PDB - 4D9U: Rsk2 C-terminal Kinase Domain, (E)-tert-butyl 3-(4-amino-7-(3-hydroxypropyl)-5-p-tolyl-7H-pyrrolo[2,3-d...
Ribosomal protein S6 kinase alpha-3. A. 342. Homo sapiens. Mutation(s): 1 Gene Names: ISPK1, MAPKAPK1B, RPS6KA3, RSK2. EC: 2.7. ... covalent inhibitors of the p90 ribosomal protein S6 kinase RSK2. A cocrystal structure revealed specific noncovalent ... Disruption of these interactions by protein unfolding or proteolysis promoted instantaneous cleavage of the covalent bond. Our ... a chemistry-based framework for engineering sustained covalent inhibition without accumulating permanently modified proteins ...
Anabolic-Androgenic Steroid Use in Sports, Health, and Socie... : Medicine & Science in Sports & Exercise
... ribosomal protein S6 kinase beta-1; ERK1/2, extracellular signal-regulated kinase 1 and 2; PI3, phosphoinositide 3-kinase; AKT ... protein kinase B; Ankrd1, ankyrin repeat domain 1; MuRF1, muscle RING-finger protein-1; MGF, mechanogrowth factor; MCT1/4, ... Effect of resistance exercise on muscle steroid receptor protein content in strength-trained men and women. Steroids. 2009;74( ... The effects of varying doses of T on insulin sensitivity, plasma lipids, apolipoproteins, and C-reactive protein in healthy ...
Molecular Vision: Kanamoto, Mol Vis 2009; 15:2762-2770. Table 1
ribosomal protein S6 kinase 3. 1.0e+000. 1.43. 21. AAC82495.1. 6.1. 66.28. 4.5. 42. ... Protein. Sequence. Theoretical value. Experimental value. Probability. Estd Z. Coverage (%). ncbi ID. pH. Mr (kDa). pH. Mr ( ... S6. PSAPL1 protein. 5.3e+001. 0.3. 7. AAH68579.1. 8.7. 60.74. 8.5. 55. ... Hypothetical protein. 9.8e-001. 1.42. 32. CAD38695.1. 10.1. 68.73. 6.0. 50. ...
Nutrients | Free Full-Text | Mechanisms of Lifespan Regulation by Calorie Restriction and Intermittent Fasting in Model...
Ribosomal Protein S6 Kinase 1 Signaling Regulates Mammalian Life Span. Science 2009, 326, 140-144. [Google Scholar] [CrossRef ... Sirtuins, silent information regulator 2 (sir2) proteins, are protein deacetylases that require NAD+ as a cofactor for the ... Iwasaki, K.; Gleiser, C.A.; Masoro, E.J.; McMahan, C.A.; Seo, E.J.; Yu, B.P. The influence of dietary protein source on ... Martins, R.; Lithgow, G.J.; Link, W. Long live FOXO: Unraveling the role of FOXO proteins in aging and longevity. Aging Cell ...
SCOP 1.55: Species: Thermus thermophilus
... from d.58.14.1 Ribosomal protein S6. Timeline for Species Thermus thermophilus [TaxId:274] from d.58.14.1 Ribosomal protein S6: ... from d.58.14.1 Ribosomal protein S6 appears in SCOP 1.57. *Species Thermus thermophilus [TaxId:274] from d.58.14.1 Ribosomal ... Other proteins in same PDB: d1g1xb_, d1g1xc_, d1g1xg_, d1g1xh_. *. Domain d1g1xf_: 1g1x F: [39328]. Other proteins in same PDB ... Family d.58.14.1: Ribosomal protein S6 [54996] (1 protein). *. Protein Ribosomal protein S6 [54997] (1 species). ...
6zp4.1 | SWISS-MODEL Template Library
40S ribosomal protein S26: D. 40S ribosomal protein S4, X isoform: E. 60S ribosomal protein L41: F. 40S ribosomal protein S6: G ... 40S ribosomal protein S7: H. 40S ribosomal protein S8: I. 40S ribosomal protein S9: J. 40S ribosomal protein S11: K. 40S ... 40S ribosomal protein S21: M. 40S ribosomal protein S15a: N. 40S ribosomal protein S24: O. 40S ribosomal protein S27: P. 40S ... 40S ribosomal protein S17: S. 40S ribosomal protein S3: T. 40S ribosomal protein S5: U. 40S ribosomal protein S10: V. 40S ...
6wd2.1 | SWISS-MODEL Template Library
30S ribosomal protein S6: 8. 30S ribosomal protein S7: 9. 30S ribosomal protein S8: a. 30S ribosomal protein S9: b. 30S ... 50S ribosomal protein L2: A. 50S ribosomal protein L3: B. 50S ribosomal protein L4: C. 50S ribosomal protein L5: D. 50S ... 50S ribosomal protein L9: F. 50S ribosomal protein L10: G. 50S ribosomal protein L11: H. 50S ribosomal protein L13: I. 50S ... 50S ribosomal protein L15: K. 50S ribosomal protein L16: L. 50S ribosomal protein L17: M. 50S ribosomal protein L18: N. 50S ...
Glibenclamide-Induced Autophagy Inhibits Its Insulin Secretion-Improving Function in β Cells
... activated protein kinase (AMPK) pathway in MIN-6 cells. Inhibition of autophagy with autophagy inhibitor 3-methyladenine (3-MA ... ribosomal protein S6 kinase) antibody (Cell Signaling Technology, USA, 2708); anti-phospho-S6K antibody (Cell Signaling ... also showed that β cells induced lysosomal degradation of proinsulin through PKD (protein kinase D) under starvation [29]. When ... The extracts were heated to 100°C for 10 min and then mixed with 6× protein loading buffer (TransGen, China, J21020) and heated ...
Celastrol inhibits the HIF-1α pathway by inhibition of mTOR/p70S6K/eIF4E and ERK1/2 phosphorylation in human hepatoma cells
The HIF-1 activation-inhibitory effects of this compound were associated with the suppression of mTOR/ribosomal protein S6 ... ribosomal protein S6 kinase (p70S6K) and eukaryotic initiation factor 4E (eIF4E) and extracellular signal-regulated kinase (ERK ... An aliquot of protein extracts was used to determine protein concentration by the Bradford method. Fifty micrograms of whole- ... To address the effect of celastrol on HIF-1α protein stability, the protein translation inhibitor CHX was used to prevent de ...
MMRRC:038370-MU
PE Mouse anti-S6 (pS244)
The N5-676 monoclonal antibody specifically detects the S6 ribosomal protein phosphorylated at S244.,/span> ... The N5-676 monoclonal antibody specifically detects the S6 ribosomal protein phosphorylated at S244.,/span> ... is a component of the 40S ribosomal subunit and belongs to the S6E family of ribosomal proteins. The S6 ribosomal protein plays ... The activated S6 ribosomal protein in turn upregulates the ribosomal translation of RNA species coding for other ribosomal ...
Publications | NCBS
Ribosomal protein S6 kinase beta-1 gene variants cause hypertrophic cardiomyopathy.. J Med Genet. 59(10):984-992.*PubMed ... FMRP Interacts with C/D Box snoRNA in the Nucleus and Regulates Ribosomal RNA Methylation.. iScience. 9:399-411.*PubMed ... Cytoplasmic poly (A) binding protein (PABPC2) critically regulates epidermal maintenance and turnover in planarian Schmidtea ...
Publications | NCBS
Anti-RPS6 antibody (GTX113542) | GeneTex
ribosomal protein S6 , S6 Background Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit ... The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with ... As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through ... This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. ...
KEGG PATHWAY: hsa05171
RPS5; ribosomal protein S5 [KO:K02989]. 6194 RPS6; ribosomal protein S6 [KO:K02991]. ... RPLP0; ribosomal protein lateral stalk subunit P0 [KO:K02941]. 6176 RPLP1; ribosomal protein lateral stalk subunit P1 [KO: ... RPLP2; ribosomal protein lateral stalk subunit P2 [KO:K02943]. 102723407 IGH; immunoglobulin heavy variable 4-38-2-like [KO: ... PRKCG; protein kinase C gamma [KO:K19663] [EC:2.7.11.13]. 5594 MAPK1; mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7. ...
Plus it
... the ribosomal protein S6 kinases pp90rsk and pp70S6K (Tan et al., 1996) and the Ras/mitogen-activated protein kinasespp42,44 ( ... as well as S6 kinases, also regulate cell hypertrophy by inducing protein synthesis, translation initiation factors, and ... Fgf2 has been shown to induce an early response gene involved in ribosomal protein synthesis, and it is required for the ... Ras and S6 kinases activate the cdk2/4 and their respective D cyclins, promoting reentry into S phase (Leone et al., 1997; ...
Model selection reveals selective regulation of blood amino acid and lipid metabolism by insulin in humans | bioRxiv
2006). Ribosomal protein S6 phosphorylation: from protein synthesis to cell size. Trends Biochem. Sci. 31, 342-348. doi:10.1016 ... In the liver, insulin activates S6 kinase through the AKT pathway, which promotes protein synthesis and causes an increase in ... 2007). Role of dietary proteins and amino acids in the pathogenesis of insulin resistance. Annu. Rev. Nutr. 27, 293-310. doi: ... S6 The features extracted by tensor decomposition. a Distribution of model parameters and Feature 1 (Fig. 3b). Circles and ...
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