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*  U7 small nuclear RNA - Wikipedia
The U7 small nuclear RNA (U7 snRNA) is an RNA molecule and a component of the small nuclear ribonucleoprotein complex (U7 snRNP ... Müller B, Link J, Smythe C (2000). "Assembly of U7 small nuclear ribonucleoprotein particle and histone RNA 3' processing in ... Azzouz TN, Schumperli D (2003). "Evolutionary conservation of the U7 small nuclear ribonucleoprotein in Drosophila melanogaster ... "The 68 kDa subunit of mammalian cleavage factor I interacts with the U7 small nuclear ribonucleoprotein and participates in 3'- ...
https://en.wikipedia.org/wiki/U7_small_nuclear_RNA
*  Inositol monophosphatase 2 - Wikipedia
Azzouz TN, Schumperli D (2004). "Evolutionary conservation of the U7 small nuclear ribonucleoprotein in Drosophila melanogaster ...
https://en.wikipedia.org/wiki/Inositol_monophosphatase_2
*  RBMX is a component of the centromere noncoding RNP complex involved in cohesion regulation, Genes to Cells | 10.1111/gtc.12562...
U7 small nuclear ribonucleoprotein represses histone gene transcription in cell cycle‐arrested cells ... Heterogeneous nuclear ribonucleoprotein G regulates splice site selection by binding to CC(A/C)‐rich regions in pre‐mRNA ... Accumulation of small murine minor satellite transcripts leads to impaired centromeric architecture and function ... To examine its function in this process, we purified satellite I ncRNP complex from nuclear extracts prepared from ...
https://www.deepdyve.com/lp/wiley/rbmx-is-a-component-of-the-centromere-noncoding-rnp-complex-involved-lXww0ZOI5H
*  US Patent # 5,698,687. Modified ribozymls - Patents.com
Cotten et al., "Ribozyme, Antisense RNA, and Antisense DNA Inhibition of U7 Small Nuclear Ribonucleoprotein-Mediated Histone ... Uhlenbeck, "A Small Catalytic Oligoribonucleotide," Nature 328:596-600 (1987). .. Uhlenbeck, Proc. Natl. Acad. Sci. USA 87:1668 ... is one order of magnitude smaller than that of the latter (k.sub.cat /K.sub.m =0.023 nM.sup.-1) (Fedor & Uhlenbeck (1990), ...
http://patents.com/us-5698687.html
*  Antisense Oligonucleotides as Pharmacological Modulators of Gene Expression | Springer for Research & Development
... and antisense DNA inhibition of U7 small nuclear ribonucleoprotein-mediated histone pre- mRNA processing in vitro. Mol Cell ... Kaneda Y, Iwai K, Uchida T (1989) Increased expression of DNA cointroduced with nuclear protein in adult rat liver. Science 243 ... Uhlenbeck OC (1987) A small catalytic oligoribonucleotide. Nature 328: 596-600PubMedGoogle Scholar ... GJS transition in normal human T-lymphocytes requires the nuclear protein encoded by c-myb. Science 24: 180-183Google Scholar ...
https://rd.springer.com/chapter/10.1007/978-3-642-75862-1_9
*  US5631148A - Ribozymes with product ejection by strand displacement - Google Patents
... and Antisense DNA Inhibition of U7 Small Nuclear Ribonucleoprotein Mediated Histone Pre mRNA Processing In Vitro; Molecular and ... and Antisense DNA Inhibition of U7 Small Nuclear Ribonucleoprotein-Mediated Histone Pre-mRNA Processing In Vitro; Molecular and ... A small catalytic RNA motif with Diels-Alderase activity. Baum et al. 2008. Deoxyribozymes: useful DNA catalysts in vitro and ... Compositions for detecting small RNAs US8399222B2 (en) 2008-11-25. 2013-03-19. Gen-Probe Incorporated. Compositions and methods ...
https://patents.google.com/patent/US5631148A/en
*  LSm - Wikipedia
Small nuclear ribonucleoproteins (snRNPs) assemble in a tightly orchestrated and regulated process that involves both the cell ... This heteroheptamer ring binds with the U7 snRNA in the U7 snRNP. The U7 snRNP mediates processing of the 3' UTR stem-loop of ... far-reaching significance of a small nuclear ribonucleoprotein". Cell. Mol. Life Sci. 61 (19-20): 2560-70. doi:10.1007/s00018- ... "Saccharomyces cerevisiae telomerase is an Sm small nuclear ribonucleoprotein particle". Nature. 401 (6749): 177-80. doi:10.1038 ...
https://en.wikipedia.org/wiki/LSm
*  Inositol monophosphatase 2
"Evolutionary conservation of the U7 small nuclear ribonucleoprotein in Drosophila melanogaster". RNA. 9 (12): 1532-41. doi: ...
https://ipfs.io/ipfs/QmXoypizjW3WknFiJnKLwHCnL72vedxjQkDDP1mXWo6uco/wiki/Inositol_monophosphatase_2.html
*  The gene for histone RNA hairpin binding protein is located on human chromosome 4 and encodes a novel type of RNA binding...
... mRNA with U7 small nuclear ribonucleoprotein and hairpin binding factors. EMBO J, 11, 691-697. ... mRNAs associate with small nuclear ribonucleoproteins during 3′ end formation in vitro. Mol Cell Biol, 7, 1663-1672. ... Reactions contained 5 μl of K21 nuclear extract (5 mg/ml) (U7 snRNP and HBP; lane 1), 2.5 μl of MonoQ fraction 24 (1 mg/ml) ( ... was used to complement a fraction rich in U7 snRNP but containing little HBP produced by fractionation of mouse K21 nuclear ...
http://emboj.embopress.org/content/16/4/769
*  SNRPE - Small nuclear ribonucleoprotein E - Homo sapiens (Human) - SNRPE gene & protein
As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. ... U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role ... SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. ... small nuclear ribonucleoprotein complex Source: UniProtKB ,p>Non-traceable Author Statement,/p> ,p>Used for statements in the ...
http://www.uniprot.org/uniprot/P62304
*  Livio Pellizzoni, PhD | Motor Neuron Center
SMN is essential for the biogenesis of U7 small nuclear ribonucleoprotein and 3'-end formation of histone mRNAs. Cell Reports, ... SMN is part of a macromolecular complex that functions in the biogenesis of small nuclear ribonucleoproteins (snRNPs) - which ... SMALL CHEMICAL MODULATORS OF SMN BIOLOGY AS CANDIDATE THERAPEUTICS FOR SMA (Federal Gov). Mar 1 2014 - Feb 28 2017 ... Ribonucleoprotein complexes in post-transcriptional gene regulation and motor neuron disease. Motor control is essential for ...
http://www.columbiamnc.org/mncenter/profile/lpellizzoni
*  SNRPB - Small nuclear ribonucleoprotein-associated proteins B and B' - Homo sapiens (Human) - SNRPB gene & protein
As part of the U7 snRNP it is involved in histone 3'-end processing. ... U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role ... SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. ... Small nuclear ribonucleoprotein-associated proteins B and B'Add BLAST. 240. Amino acid modifications. Feature key. Position(s) ...
http://www.uniprot.org/uniprot/P14678
*  Octamer-binding factor 6 (Oct-6/Pou3f1) is induced by interferon and contributes to dsRNA-mediated transcriptional responses |...
Lsm10 is a component of the U7 small nuclear ribonucleoprotein (snRNP) complex, which is involved in the formation of the 3' ... Oct-6 contains a nuclear localisation and a nuclear export signal, both located in the POU homeodomain [36, 37]. Although so ... Pillai RS, Will CL, Luhrmann R, Schumperli D, Muller B: Purified U7 snRNPs lack the Sm proteins D1 and D2 but contain Lsm10, a ... Yang XC, Torres MP, Marzluff WF, Dominski Z: Three proteins of the U7-specific Sm ring function as the molecular ruler to ...
https://bmccellbiol.biomedcentral.com/articles/10.1186/1471-2121-11-61
*  Like-Sm (LSM) domain containing protein, LSm4/SmD1/SmD3 (IPR027141) | InterPro | EMBL-EBI
SmD3 is a core protein of small nuclear ribonucleoprotein (snRNP) essential for splicing of primary transcripts [PMID: 21421416 ... Purified U7 snRNPs lack the Sm proteins D1 and D2 but contain Lsm10, a new 14 kDa Sm D1-like protein.. EMBO J. 20 5470-9 2001 ... Saccharomyces cerevisiae telomerase is an Sm small nuclear ribonucleoprotein particle.. Nature 401 177-80 1999 ... including the D1 core polypeptide of small nuclear ribonucleoprotein particles.. Proc. Natl. Acad. Sci. U.S.A. 90 848-52 1993 ...
http://www.ebi.ac.uk/interpro/entry/IPR027141
*  Small nuclear RNA - Wikipedia
Through the study of small nuclear ribonucleoproteins (snRNPs) and small nucleolar (sno)RNPs we have been able to better ... U7 snRNA has been found to function in histone pre-mRNA processing. The second class, known as Lsm-class snRNA, consists of U6 ... Small nuclear ribonucleic acid (snRNA), also commonly referred to as U-RNA, is a class of small RNA molecules that are found ... Small Nuclear RNA at the US National Library of Medicine Medical Subject Headings (MeSH) Small Nucleolar RNA at the US National ...
https://en.wikipedia.org/wiki/Small_nuclear_RNA
*  What does ribonucleoprotein, u4-u6 small nuclear mean?
Meaning of ribonucleoprotein, u4-u6 small nuclear. What does ribonucleoprotein, u4-u6 small nuclear mean? Information and ... translations of ribonucleoprotein, u4-u6 small nuclear in the most comprehensive dictionary definitions resource on the web. ... u4-u6 small nuclear in the Definitions.net dictionary. ... ribonucleoprotein, u5 small nuclear. *ribonucleoprotein, u7 ... What does ribonucleoprotein, u4-u6 small nuclear mean?. Definitions for ribonucleoprotein, u4-u6 small nuclear. Here are all ...
https://www.definitions.net/definition/ribonucleoprotein,%20u4-u6%20small%20nuclear
*  U7 small nuclear RNA in C snurposomes of the Xenopus germinal vesicle. - Semantic Scholar
They stain intensely with antibodies against trimethylguanosine and the small nuclear ribonucleoprotein-specific Sm antigen but ... Because they contain U7 snRNA and occur at the sites of histone pre-mRNA synthesis, C snurposomes presumably play a role in ... Xenopus U7 is 58 nucleotides long and is capped at the 5' end with trimethylguanosine. C snurposomes are often associated with ... We show here that C snurposomes in the Xenopus germinal vesicle contain U7 snRNA, an snRNA of low abundance involved in ...
https://www.semanticscholar.org/paper/U7-small-nuclear-RNA-in-C-snurposomes-of-the-Wu-Gall/81860dd088951fa5820187751514b5b36ef1653c
*  Shopping Page. Buy or upgrade website. - Healthmatics | Page 89
RIBONUCLEOPROTEINS, SMALL NUCLEAR). Many function in the processing of messenger RNA precursors. Others, the snoRNAs (RNA, ... Seven known snRNAs have been termed U1 through U7 snRNA.. NCI. More Details ... Small nuclear RNA. A class of abundant small nuclear RNAs involved in RNA processing (splicing, 3` end maturation). These ... that are abundant in the nucleus and usually complexed with proteins in small nuclear ribonucleoproteins; many function in the ...
http://healthmatics.info/products-page/89/
*  SNRPD3 Gene - GeneCards | SMD3 Protein | SMD3 Antibody
Small Nuclear Ribonucleoprotein D3 Polypeptide, including: function, proteins, disorders, pathways, orthologs, and expression. ... SNRPD3 (Small Nuclear Ribonucleoprotein D3 Polypeptide) is a Protein Coding gene. Diseases associated with SNRPD3 include Lupus ... Component of the U7 snRNP complex, or U7 Sm protein core complex, at least composed of LSM10, LSM11, SNRPB, SNRPD3, SNRPE, ... cDNA cloning of the Sm proteins D2 and D3 from human small nuclear ribonucleoproteins: evidence for a direct D1-D2 interaction. ...
http://www.genecards.org/cgi-bin/carddisp.pl?gene=SNRPD3
*  Nikolay G Kolev, PhD | Yale School of Public Health
Tycowski, K.T., Kolev, N.G., Conrad, N.K., Fok, V. and Steitz, J.A. The ever-growing world of small nuclear ribonucleoproteins ... In vivo assembly of functional U7 snRNP requires RNA backbone flexibility within the Sm-binding site. Kolev, N.G. and Steitz, J ... Kolev NG, Steitz JA: In vivo assembly of functional U7 snRNP requires RNA backbone flexibility within the Sm-binding site. Nat ... Genome-wide analysis of small nucleolar RNAs of Leishmania major reveals a rich repertoire of RNAs involved in modification and ...
http://medicine.yale.edu/ysph/about/contact/nikolay_kolev-2.profile
*  Enhanced exon-skipping induced by U7 snRNA carrying a splicing silencer sequence: Promising tool for DMD therapy. - Physiology,...
Specific exon skipping can be achieved using synthetic oligonucleotides or viral vectors encoding modified small nuclear RNAs ( ... that enhanced exon skipping can be induced by a U7 snRNA carrying binding sites for the heterogeneous ribonucleoprotein A1 ( ... hnRNPA1). In DMD patient cells, bifunctional U7 snRNAs harboring silencer motifs induce complete skipping of exon 51, and thus ... vectors encoding the bifunctional U7 snRNA. These new constructs are very promising for the optimization of therapeutic exon ...
https://www.dpag.ox.ac.uk/publications/106373
*  Recombinant Human SNRPG protein (ab105596) | Abcam
Small nuclear ribonucleoprotein G. *Small nuclear ribonucleoprotein polypeptide G. *SmG. *snRNP-G ... Appears to function in the U7 snRNP complex that is involved in histone 3'-end processing. Associated with snRNP U1, U2, U4/U6 ...
http://www.abcam.com/recombinant-human-snrpg-protein-ab105596.html
*  SNRPB gene - Genetics Home Reference - NIH
small nuclear ribonucleoprotein polypeptides B and B1. Enable Javascript to view the expand/collapse boxes.. Open All Close All ... As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing (PubMed:12975319). ... U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (PubMed:11991638, PubMed:18984161, ... The protein encoded by this gene is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ...
https://ghr.nlm.nih.gov/gene/SNRPB
*  SMART: Sm domain annotation
The spliceosomal small nuclear ribonucleoproteins (snRNPs) U1, U2, U4/U6 and U5 share eight proteins B', B, D1, D2, D3, E, F ... such as U7 snRNP, can contain different Lsm proteins. ... The U1, U2, U4/U6, and U5 small nuclear ribonucleoprotein ... small nuclear ribonucleoprotein particles (snRNPs) involved in pre-mRNA splicing. Interpro abstract (IPR001163):. This domain ... The Sm proteins form part of specific small nuclear ribonucleoproteins (snRNPs) that are involved in the processing of pre- ...
http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00651
*  Exon-skipping advances for Duchenne muscular dystrophy, Human Molecular Genetics | 10.1093/hmg/ddy171 | DeepDyve
Studies using U7 or U1 small nuclear RNA (snRNA) to carry the antisense sequences have demonstrated efficient and sustained ... Altogether the U7snRNA associated with the specific U7 sm protein form the U7snRNP (ribonucleoprotein complex), playing a role ... Studies using U7 or U1 small nuclear RNA (snRNA) to carry the antisense sequences have demonstrated efficient and sustained ... recruiting NCT02530905 AAV-U7/Exon 53 Genethon 53 AAV/U7 Observational Ongoing NCT01385917 AAV-U7/Exon 53 Genethon 53 AAV/U7 I/ ...
https://www.deepdyve.com/lp/ou_press/exon-skipping-advances-for-duchenne-muscular-dystrophy-p0n8nhOu6j