Loading...
*  Lipofuscin - wikidoc
ML Katz, LM Rice and CL Gao, "Reversible accumulation of lipofuscin-like inclusions in the retinal pigment epithelium", ... It is considered one of the aging or "wear and tear" pigments; found in the liver, kidney, heart muscle, adrenals, nerve cells ... Lipofuscin is the name given to finely granular yellow brown pigment granules composed of lipid-containing residues of ...
http://www.wikidoc.org/index.php/Lipofuscin
*  Age Related Macular Degeneration | Wet AMD | Non-Neovascular Macular Degeneration
Sub-RPE Fluid - Fluid below the retinal pigment epithelium. Sub-RPE Blood - Blood below the retinal pigment epithelium ... ARMD is a degenerative disorder of the retina and the tissues below the retina called the retinal pigment epithelium (RPE), ... Retinal Pigment Epithelium (RPE) - cells below the photoreceptors that engulf waste from overlying photoreceptors and process, ... Abnormal sub-retinal or intra-retinal blood vessel growth. Lipofuscin - Waste products of retinal photoreceptor metabolism. ...
http://www.retinacenternj.com/diseases-treatment/age-related-macular-degeneration-wet-amd-or-non-ne
*  Gene Therapy for Leber's Congenital Amaurosis
LCA Type 2, one of the more common types, is caused by a defect in the RPE65 gene (Retinal Pigment Epithelium-specific Protein ... disease and principle investigator for Europes first clinical trial in the use of stem cell drived-retinal pigment epithelium ... James Bainbridge is an NIHR Research Professor and Professor of Retinal Studies at the UCL Institute of Ophthalmology. He has ... provides an update into gene therapy research into interventions for inherited retinal diseases including an update on the ...
http://www.brcophthalmology.org/gene-therapy-lebers-congenital-amaurosis
*  RPE65 Antibody | scrazzl.com - Simply Connecting Science
Retinal pigment epithelium-specific 65 kDa protein, retinal pigment epithelium-specific protein (65kD), retinal pigment ... Novel organotypic culture model of adult mammalian neurosensory retina in co-culture with retinal pigment epithelium. ... Iron regulates L-cystine uptake and glutathione levels in lens epithelial and retinal pigment epithelial cells by its effect on ... Reactivation of uveitogenic T cells by retinal astrocytes derived from experimental autoimmune uveitis-prone B10RIII mice. ...
http://scrazzl.com/874175/rpe65-antibody
*  RPE65 Antibody | scrazzl.com - Simply Connecting Science
... retinal pigment epithelium-specific protein (65kD), retinal pigment epithelium-specific protein 65kDa, retinitis pigmentosa 20 ... Retinal pigment epithelium-specific 65 kDa protein, rd12, Retinol isomerase, retinoid isomerohydrolase, RP20, sRPE65. ...
http://scrazzl.com/874178/rpe65-antibody
*  Glucose Transporters in Retinal Pigment Epithelium Development | SpringerLink
... the endothelia and epithelia of the blood-brain barrier allow little glucose to diffuse across their paracellular... ... Tight Junction Retinal Pigment Epithelium Retinal Pigment Epithelium Cell Transepithelial Electrical Resistance Neural Retina ... Epithelium-capillary interactions in the eye: The retinal pigment epithelium and the choriocapillaris. Int Rev Cytol 1989;114: ... The retinal pigment epithelium induces fenestration of endothelial cells in vivo. Curr Eye Res 1992;11:863-873.PubMedCrossRef ...
https://link.springer.com/chapter/10.1007/978-1-59745-375-2_10
*  Retinal pigment epithelium detach... preview & related info | Mendeley
Purpose: To report the unusual association of vitreomacular traction syndrome (VMT) with retinal pigment epithelium (RPE) ... Conclusion: Retinal pigment epithelium detachment could be associated with VMT. Although the incidence is rare, it may ... Retinal pigment epithelium detachment associated with vitreomacular traction syndrome - Case report. *Georgalas I ... Purpose: To report the unusual association of vitreomacular traction syndrome (VMT) with retinal pigment epithelium (RPE) ...
https://www.mendeley.com/research-papers/retinal-pigment-epithelium-detachment-associated-vitreomacular-traction-syndrome-case-report/
*  Interactions between the retinal pigment epithelium and the neural retina | SpringerLink
In these interactions the RPE acts as three types of cell - epithelium, macrophage,... ... The retinal pigment epithelium (RPE) interacts with the photoreceptors, which it faces across the subretinal space. ... Pigment movement and cellular contractility in the retinal pigment epithelium. In: The retinal pigment epithelium, Marmor MF ... Bok D and Young R (1979) Phagocytic properties of the retinal pigment epithelium. In: The retinal pigment epithelium eds: Zinn ...
https://link.springer.com/article/10.1007/BF00158922
*  Beta cyclodextrins bind, stabilize, and remove lipofuscin bisretinoids from retinal pigment epithelium | PNAS
Accumulation of lipofuscin bisretinoids (LBs) in the retinal pigment epithelium (RPE) is the alleged cause of retinal ... 2010) The retinal pigment epithelium in health and disease. Curr Mol Med 10(9):802-823. ... 2005) The retinal pigment epithelium in visual function. Physiol Rev 85(3):845-881. ... The retinal pigment epithelium (RPE), strategically situated between the neural retina and the choroid blood vessels, is ...
http://www.pnas.org/content/111/14/E1402
*  IJMS | Free Full-Text | NLRP3 Upregulation in Retinal Pigment Epithelium in Age-Related Macular Degeneration
... and pro-IL-18 in AMD lesions of the retinal pigment epithelium (RPE) and photoreceptor. In vitro, a similar increase was evoked ... stimulation in the adult retinal pigment epithelium (ARPE-19) cell line, and the increase was reduced in siRNA transfected ... NLRP3 Upregulation in Retinal Pigment Epithelium in Age-Related Macular Degeneration Yujuan Wang 1,2, Jakub W. Hanus 3, Mones S ... "NLRP3 Upregulation in Retinal Pigment Epithelium in Age-Related Macular Degeneration." Int. J. Mol. Sci. 17, no. 1: 73. ...
https://www.mdpi.com/1422-0067/17/1/73
*  Retinoid metabolism in cultured human retinal pigment epithelium | Biochemical Journal
Retinoid metabolism in cultured human retinal pigment epithelium Message Subject (Your Name) has forwarded a page to you from ... Retinoid metabolism in cultured human retinal pigment epithelium. S R Das, P Gouras ... Uptake, esterification and release of all-trans-retinol in primary cultures of human retinal epithelium were studied. Cultured ... This led to incorporation of retinal and the formation of all-trans- and 11-cis-retinyl palmitate. The metabolism of the all- ...
http://www.biochemj.org/content/250/2/459?ijkey=394330644cd8e655ff13a76b8c30fd28af947be2&keytype2=tf_ipsecsha
*  Pump-probe detection of laser-induced microbubble formation in retinal pigment epithelium cells
... ... "Pump-probe detection of laser-induced microbubble formation in retinal pigment epithelium cells," Journal of Biomedical Optics ... "Pump-probe detection of laser-induced microbubble formation in retinal pigment epithelium cells," J. Biomed. Opt. 9(2) (1 March ... being investigated in a new ophthalmic procedure for treatment of disorders associated with the retinal pigment epithelium (RPE ...
https://www.spiedigitallibrary.org/journals/Journal-of-Biomedical-Optics/volume-9/issue-2/0000/Pump-probe-detection-of-laser-induced-microbubble-formation-in-retinal/10.1117/1.1646413.short
*  Nutrient utilization and metabolite transport in retinal pigment epithelium | IOVS | ARVO Journals
Nutrient utilization and metabolite transport in retinal pigment epithelium Jianhai Du; Kaitlen Knight; Christina Lieu; Connor ... Nutrient utilization and metabolite transport in retinal pigment epithelium You will receive an email whenever this article is ... Purpose : The retinal pigment epithelium (RPE) is essential to maintaining metabolic homeostasis in the outer retina. How RPE ... Nutrient utilization and metabolite transport in retinal pigment epithelium. Invest. Ophthalmol. Vis. Sci. 2016;57(12):1751. ...
https://iovs.arvojournals.org/article.aspx?articleid=2560325
*  Extracellular ATP Activates Calcium Signaling, Ion, and Fluid Transport in Retinal Pigment Epithelium | Journal of Neuroscience
The retinal pigment epithelium (RPE) forms a major component of the blood-retinal barrier. It has two functionally distinct ... 1994) Properties of the inwardly rectifying K+ conductance in the toad retinal pigment epithelium. J Physiol (Lond) 476:41-53. ... 1992) α1-Adrenergic modulation of K and Cl transport in bovine retinal pigment epithelium. J Gen Physiol 99:263-290. ... 1991) pHi regulation in frog retinal pigment epithelium: two apical membrane mechanisms. Am J Physiol 261:C132-C142. ...
http://www.jneurosci.org/content/17/7/2324
*  Identification of Surface Proteome for Human Retinal Pigment Epithelium | IOVS | ARVO Journals
Identification of Surface Proteome for Human Retinal Pigment Epithelium Alejandro Morales Martinez; Vladimir Khristov; Andrea ... Identification of Surface Proteome for Human Retinal Pigment Epithelium You will receive an email whenever this article is ... Purpose: The degeneration of the retinal pigment epithelium (RPE) plays a major role in photoreceptor cell death and vision ... Identification of Surface Proteome for Human Retinal Pigment Epithelium. Invest. Ophthalmol. Vis. Sci. 2015;56(7 ):2336. ...
https://iovs.arvojournals.org/article.aspx?articleid=2332107
*  Retinal pigment epithelium - Wikipedia
The pigmented layer of retina or retinal pigment epithelium (RPE) is the pigmented cell layer just outside the neurosensory ... "Relative contributions of the neurosensory retina and retinal pigment epithelium to macular hypofluorescence." Arch Ophthalmol ... Coscas, Gabriel & Felice Cardillo Piccolino (1998). Retinal Pigment Epithelium and Macular Diseases. Springer. ISBN 0-7923-5144 ... "The retinal pigment epithelium in visual function". Physiol Rev 85:845-81 Steinberg RH, Linsenmeier RA, Griff ER (1983) "Three ...
https://en.wikipedia.org/wiki/Retinal_pigment_epithelium
*  Bone morphogenetic proteins specify the retinal pigment epithelium in the chick embryo | Development
Bone morphogenetic proteins specify the retinal pigment epithelium in the chick embryo ... Bone morphogenetic proteins specify the retinal pigment epithelium in the chick embryo ... Bone morphogenetic proteins specify the retinal pigment epithelium in the chick embryo ... Bone morphogenetic proteins specify the retinal pigment epithelium in the chick embryo ...
http://dev.biologists.org/content/early/2007/08/29/dev.02884
*  Carbonic anhydrase XIV is enriched in specific membrane domains of retinal pigment epithelium, Müller cells, and astrocytes |...
Carbonic anhydrase XIV is enriched in specific membrane domains of retinal pigment epithelium, Müller cells, and astrocytes. ... Carbonic anhydrase XIV is enriched in specific membrane domains of retinal pigment epithelium, Müller cells, and astrocytes ... Carbonic anhydrase XIV is enriched in specific membrane domains of retinal pigment epithelium, Müller cells, and astrocytes ... Carbonic anhydrase XIV is enriched in specific membrane domains of retinal pigment epithelium, Müller cells, and astrocytes ...
https://www.pnas.org/content/102/22/8030?ijkey=a8d9e66e65ef2caddac684322c10fe8591d261a3&keytype2=tf_ipsecsha
*  A regulatory loop involving PAX6, MITF, and WNT signaling controls retinal pigment epithelium development. | Sigma-Aldrich
A regulatory loop involving PAX6, MITF, and WNT signaling controls retinal pigment epithelium development.. [Kapil Bharti, ... The separation of the optic neuroepithelium into future retina and retinal pigment epithelium (RPE) is a critical event in ... that careful manipulation of the Pax6 regulatory circuit may facilitate the generation of retinal and pigment epithelium cells ... also plays a crucial role in early pigment epithelium development. This role is seen, however, only in a background genetically ...
https://www.sigmaaldrich.com/catalog/papers/22792072
*  Experimental Transplant of Retinal Pigment Epithelium for Ophthalmic Disease | Retina International
The retinal pigment epithelium (RPE) is a layer of cells in the retina behind the photoreceptors that is necessary for vision. ... In recent years, several international research groups have been working to replace the damaged retinal pigment epithelium by ... retinal pigment epithelial cell'. These very specific cells were made in the laboratory from induced pluripotent stem cells ( ... It verifies the safety and efficacy of the transplant of this retinal cell layer that has been grown in the laboratory from ...
http://www.retina-international.org/experimental-transplant-retinal-pigment-epithelium-ophthalmic-disease
*  MAP kinase pathways in UV-induced apoptosis of retinal pigment epithelium ARPE19 cells
Keywords: retinal pigment epithelium cells ; apoptosis ; MAP kinases ; ultra violet ; Ap-1 ; kinases inhibitors ; Activated ... The retinal pigment epithelium (RPE) is constantly exposed to external injuries which lead to degeneration, dysfunction or loss ... MAP kinase pathways in UV-induced apoptosis of retinal pigment epithelium ARPE19 cells. Roduit, Raphael; Schorderet, Daniel F. ... In this study, human retinal pigment epithelial cells ARPE19 were exposed to 100 J/m(2) stop of UV-C and MAPK pathways were ...
https://infoscience.epfl.ch/record/161173
*  Retinal pigmented epithelium determination requires the redundant activities of Pax2 and Pax6 | Development
Epithelia-mesenchyme interaction plays an essential role in transdifferentiation of retinal pigment epithelium of silver mutant ... Bumsted, K. M. and Barnstable, C. J. (2000). Dorsal retinal pigment epithelium differentiates as neural retina in the ... le, lens; nr, neural retina; os, optic stalk; ov, optic vesicle; rpe, retinal pigmented epithelium; se, surface ectoderm. ... Retinal pigmented epithelium determination requires the redundant activities of Pax2 and Pax6 ...
http://dev.biologists.org/content/130/13/2903
*  Retinal Pigment Epithelium-Derived CTLA-2α Induces TGFβ-Producing T Regulatory Cells | The Journal of Immunology
Retinal Pigment Epithelium-Derived CTLA-2α Induces TGFβ-Producing T Regulatory Cells. Sunao Sugita, Shintaro Horie, Orie ... Ocular pigment epithelium contributes to immune tolerance in the eye (1, 2, 3). Previous studies have shown that the retinal ... retina pigment epithelium; CathB, cathepsin B; CathL, cathepsin L; CBPE, ciliary body pigment epithelium; DN, dominant negative ... Evidence that retinal pigment epithelium functions as an immune-privileged tissue. Invest. Ophthalmol. Visual Sci. 41: 3467- ...
https://www.jimmunol.org/content/181/11/7525?ijkey=6b4fef1f49425c4a1c8af6a572d414bb54c31aa7&keytype2=tf_ipsecsha
*  Presumed Adenocarcinoma of the Retinal Pigment Epithelium in a Blind Eye With a Staphyloma
The retinal pigment epithelium (RPE) can undergo reactive hyperplasia and metaplasia following a variety of ocular insults. ... Presumed Adenocarcinoma of the Retinal Pigment Epithelium in a Blind Eye With a Staphyloma. ...
https://insights.ovid.com/aoop/199804000/00000820-199804000-00016
*  FcRn mediated IgG transport by retinal pigment epithelium cells | Journal of Translational Medicine | Full Text
van Bilsen K, van Hagen PM, Bastiaans J: The neonatal Fc receptor is expressed by human retinal pigment epithelial cells and is ... we showed that human retinal pigment epithelial (RPE) cells express FcRn and that, in contrast to non-ocular cells, TNF-α ... This research project was funded by grants from UitZicht and the International Retinal Research Foundation. ...
https://translational-medicine.biomedcentral.com/articles/10.1186/1479-5876-10-S3-P2