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*  Remote ischaemic preconditioning and postconditioning and the reperfusion injury salvage kinase pathway | Heart
Introduction The Reperfusion Injury Salvage Kinase (RISK) pathway is the term given to prosurvival kinases such as the ... Remote ischaemic preconditioning and postconditioning and the reperfusion injury salvage kinase pathway ... Remote ischaemic preconditioning and postconditioning and the reperfusion injury salvage kinase pathway ... Applying brief ischaemia/reperfusion to a limb either before myocardial ischaemia (remote ischaemic preconditioning; RIPC) or ...
http://heart.bmj.com/content/95/Suppl_1/13
*  Insulin and GSK3β-inhibition abrogates the infarct sparing-effect of ischemic postconditioning in ex vivo rat hearts
Pharmacological treatment of reperfusion injury using insulin and GSK3β inhibition has been shown to be cardioprotective, ... Langendorff perfused ex vivo rat hearts were subjected to 30 min of regional ischemia and 120 min of reperfusion. For the first ... Pharmacological reperfusion treatment with insulin and SB41 interferes with the cardioprotection afforded by ischemic ... combining either of the pharmacological reperfusion treatments with IPost completely abrogated the cardioprotection afforded by ...
https://brage.bibsys.no/xmlui/handle/11250/2453182
*  Ischemia-Reperfusion Injury and Anesthesia
... Guest Editors: Ahmet Eroglu, Engin Erturk, Can Ince, and Martin Westphal *Ischemia- ... Ischemia-Reperfusion Injury and Volatile Anesthetics, Engin Erturk Review Article (7 pages), Article ID 526301, Volume 2014 ( ... The Effect of Intravenous Anesthetics on Ischemia-Reperfusion Injury, Ahmet Eroglu Review Article (7 pages), Article ID 821513 ... The Effects of Spinal, Inhalation, and Total Intravenous Anesthetic Techniques on Ischemia-Reperfusion Injury in Arthroscopic ...
https://www.hindawi.com/journals/bmri/si/842383/
*  Oxidative Stress-Mediated Reperfusion Injury 2014
... Zhengyuan Xia,1,2 Yanfang Chen,3,4 Qian Fan,5 Mengzhou Xue,6 and Ke-xuan Liu ... Zhengyuan Xia, Yanfang Chen, Qian Fan, Mengzhou Xue, and Ke-xuan Liu, "Oxidative Stress-Mediated Reperfusion Injury 2014," ...
https://www.hindawi.com/journals/omcl/2015/689416/cta/
*  Chuanfu Li, MD - Ischemia/Reperfusion Injury
Innate Immunity in Myocardial Ischemia/reperfusion Injury Our research focuses on understanding the role in innate immunity in ... We are interested in the role of Toll-like receptor (TLR) mediated signaling pathways in myocardial ischemia/reperfusion injury ... myocardial ischemia/reperfusion (I/R) injury. A growing body of evidence suggests that inflammatory pathways initiated by the ... and pro-inflammatory signaling mechanisms associated with myocardial I/R injury. ...
https://www.etsu.edu/com/surgery/research/chauanfuli.php
*  Patent US7635680 - Attenuation of reperfusion injury - Google Patents
... enhancing the survivability of platelets during storage or transfusion and to attenuate ischemia-reperfusion injury (IPI), are ... The modified annexin decreases the binding of leukocytes and platelets during post-ischemic reperfusion, thereby restoring ... myocytes are viable before reperfusion then progress to irreversible injury during reperfusion. Apoptosis can contribute to ... up to at least about 3 hours prior to reperfusion, up to at least about 1 hour prior to reperfusion, during reperfusion, and/or ...
http://www.google.com/patents/US7635680?dq=6,411,947
*  New Therapy for Bowel Ischemia-Reperfusion Injury
... at the beginning of reperfusion attenuated tissue injury and inflammatory responses in a rat model of gut I/R induced by ... attenuates organ injury and inflammation responses, and reduces mortality following gut I/R injury. The primary aim of this ... Although we have shown that administration of rat AM plus human AMBP-1 at the beginning of reperfusion is protective, it ... As such, the development of effective strategies for preventing and treating circulatory collapse and organ injury after gut I/ ...
https://www.sbir.gov/print/sbirsearch/detail/332873
*  Reperfusion Injury | CTD
Injuries, Ischemia-Reperfusion , Injuries, Reperfusion , Injury, Ischemia Reperfusion , Injury, Ischemia-Reperfusion , Injury, ... Ischemia Reperfusion Injury , Ischemia-Reperfusion Injury , Reperfusion Damage , Reperfusion Damages , Reperfusion Injuries ... Reperfusion Injury 2.. Diseases ← Pathological Conditions, Signs and Symptoms ← Pathologic Processes ← Postoperative ... Reperfusion Injury Synonyms Damage, Reperfusion , Damages, Reperfusion , ...
http://ctd.mdibl.org/detail.go?type=disease&acc=MESH%3AD015427
*  Smad1 Protects Cardiomyocytes From Ischemia-Reperfusion Injury | Circulation
Reperfusion injury induces apoptosis in rabbit cardiomyocytes. J Clin Invest. 1994; 94: 1621-1628. ... Smad1 Protects Cardiomyocytes From Ischemia-Reperfusion Injury. Mitsuru Masaki, Masahiro Izumi, Yuichi Oshima, Yoshikazu ... Nakamura T, Mizuno S, Matsumoto K, Sawa Y, Matsuda H. Myocardial protection from ischemia/reperfusion injury by endogenous and ... Smad1 Protects Cardiomyocytes From Ischemia-Reperfusion Injury. Mitsuru Masaki, Masahiro Izumi, Yuichi Oshima, Yoshikazu ...
http://circ.ahajournals.org/content/111/21/2752
*  Fibrin-Derived Peptide FX06 Reduces Cardiac Reperfusion Injury
After 4 months, the resulting scar mass was reduced by 37%, suggesting that a reduction of reperfusion injury indeed may lead ... Cardiology »F.I.R.E. »FX06 »Fibrin-Derived »PCI »Reperfusion »STEMI »Thrombolysis »blood flow »blood vessel »myocardial ... Further reports about: , Cardiology , F.I.R.E. , FX06 , Fibrin-Derived , PCI , Reperfusion , STEMI , Thrombolysis , blood flow ... "reperfusion injury". FX06 is a novel compound intended to prevent that damage. ...
http://www.innovations-report.com/hrml/reports/studies/fibrin-derived-peptide-fx06-reduces-cardiac-117326.html
*  JCI - Myocardial ischemia-reperfusion injury: a neglected therapeutic target
Lethal myocardial reperfusion injury. Reperfusion-induced death of cardiomyocytes that were viable at the end of the index ... Lethal myocardial reperfusion injury attenuates the full benefits of myocardial reperfusion in terms of MI size reduction and ... Reduction of infarct size by gentle reperfusion without activation of reperfusion injury salvage kinases in pigs. Cardiovasc ... This figure illustrates the individual contributions of acute myocardial ischemic injury and myocardial reperfusion injury to ...
https://www.jci.org/articles/view/62874
*  IJMS | Free Full-Text | Proteasome and Organs Ischemia-Reperfusion Injury
... the addition of proteasome inhibitor in the preservation solution alleviated the injuries due to the ischemia-reperfusion ... When the organ is ready for the transplantation, the reperfusion of the organ induces an increase of the oxidative stress, ... and pharmacological compounds that regulate the proteasome in protecting the organs from the ischemia-reperfusion injury. ... Keywords: ischemia-reperfusion injury; proteasome; organs; inflammation ischemia-reperfusion injury; proteasome; organs; ...
https://www.mdpi.com/1422-0067/19/1/106
*  Myocardial Reperfusion Injury Summary Report | CureHunter
Reperfusion takes place when there is spontaneous thrombolysis, THROMBOLYTIC THERAPY, collateral flow from other coronary ... Damage to the MYOCARDIUM resulting from MYOCARDIAL REPERFUSION (restoration of blood flow to ischemic areas of the HEART.) ... Myocardial Ischemic Reperfusion Injury; Injuries, Myocardial Reperfusion; Myocardial Reperfusion Injuries; Reperfusion Injuries ... Myocardial Reperfusion Injury. Subscribe to New Research on Myocardial Reperfusion Injury Damage to the MYOCARDIUM resulting ...
http://www.curehunter.com/public/keywordSummaryD015428-Myocardial-Reperfusion-Injury.do
*  Ischemia Reperfusion Injury - Pipeline Review, H2 2015 Is Released - iData Insights
Ischemia Reperfusion Injury - Pipeline Review, H2 2015, provides an... ... Ischemia Reperfusion Injury - Pipeline Review, H2 2015 Summary Global Markets Direct s, ... Ischemia Reperfusion Injury - Pipeline Review, H2 2015 Summary Global Markets Direct s, Ischemia Reperfusion Injury - Pipeline ... Ischemia Reperfusion Injury - Therapeutics under Development by Companies 11. Ischemia Reperfusion Injury - Therapeutics under ...
http://www.mynewsdesk.com/in/pressreleases/ischemia-reperfusion-injury-pipeline-review-h2-2015-is-released-1299785
*  Ischemia Reperfusion Injury Market H2 2015 Pipeline Analysis: RnR Market Research
Ischemia Reperfusion Injury' spread across 178 pages at http://www.rnrmarketresearch.com/ischemia-reperfusion-injury-pipeline- ... Coverage of the Ischemia Reperfusion Injury pipeline on the basis of target, MoA, route of administration and molecule type ... It also reviews key players involved in the therapeutic development for Ischemia Reperfusion Injury and special features on ... The report reviews key players involved in the therapeutics development for Ischemia Reperfusion Injury and enlists all their ...
http://www.pitchengine.com/pitches/2a950b1a-cba7-4862-9507-ffbcdd076dc6
*  Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS. - PubMed - NCBI
Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS.. Chouchani ET#1,2, Pell VR#2, Gaude ... Ischaemia-reperfusion injury occurs when the blood supply to an organ is disrupted and then restored, and underlies many ... Succinate: A Promising Therapeutic Target for Reperfusion Injury. [Neurosurgery. 2015]. *Biochemistry: succinate strikes. [ ... Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS. Nature. 2014 Nov 20;515(7527):431- ...
https://www.ncbi.nlm.nih.gov/pubmed/25383517?dopt=Abstract
*  AHA: Human Atrial Natiuretic Peptide May Reduce Reperfusion Injury | Medpage Today
Stenting for an acute myocardial infarction has a better outcome when the reperfusion is followed up with an infusion of ... Carperitide also reduced reperfusion injury by 25.9% compared with placebo (P=0.019), said Dr. Kitakaze, reporting the results ... noted that about a dozen drugs that were tested for reduction of infarct size and reperfusion injury "all reported early, ... did not reduce infarct size or reduce reperfusion injury. ... Human Atrial Natiuretic Peptide May Reduce Reperfusion Injury. ...
https://www.medpagetoday.com/meetingcoverage/aha/4526
*  ischemic reperfusion injury - Semantic Scholar
Role of IL-1 in renal ischemic reperfusion injury.. *Mamnunal Haq, James C Norman, Sabiha R. Saba, Germán Mauricio Mejía ... Antibodies to ICAM-1 protect kidneys in severe ischemic reperfusion injury.. *Hamid Rabb, César Mendiola, +4 authors Germán ... Splenectomy protects the kidneys against ischemic reperfusion injury in the rat.. *Toshiya Hiroyoshi, Masahiro Tsuchida, +4 ... Cardioprotective effects of grape seed proanthocyanidin against ischemic reperfusion injury.. *Motoaki Sato, Gautam Maulik, ...
https://www.semanticscholar.org/topic/ischemic-reperfusion-injury/982489
*  Clinical perspectives on reperfusion injury in acute myocardial infarction.
The current review outlines the multifocal mechanisms of reperfusion injury and focuses on under ... However, reperfusion itself may contribute to myocardial cell death. ... Prompt reperfusion therapy in acute myocardial infarction enhances clinical outcome. ... The current review outlines the multifocal mechanisms of reperfusion injury and focuses on understanding the potential role of ...
http://www.biomedsearch.com/nih/Clinical-perspectives-reperfusion-injury-in/24766972.html
*  Salvianolate for treatment of cerebral ischemia-reperfusion injuries | EurekAlert! Science News
... and improves energy metabolism against cerebral ischemia-reperfusion injuries. Dr. Wei Lu and his team from the Second Xiangya ... Hospital, Central South University, China found that administration of salvianolate during reperfusion after ischemia appears ... Salvianolate increases heat shock protein expression in a cerebral ischemia-reperfusion injury model. Neural Regen Res. 2013;8( ... Salvianolate for treatment of cerebral ischemia-reperfusion injuries. Neural Regeneration Research. Journal. Neural ...
https://www.eurekalert.org/pub_releases/2013-10/nrr-sft102513.php
*  JCI - Inadequate ubiquitination-proteasome coupling contributes to myocardial ischemia-reperfusion injury
Reperfusion injury and reactive oxygen species: The evolution of a concept. Redox Biol. 2015;6:524-551.. View this article via ... Inadequate ubiquitination-proteasome coupling contributes to myocardial ischemia-reperfusion injury. Chengjun Hu,1,2 Yihao Tian ... Endoplasmic reticulum stress gene induction and protection from ischemia/reperfusion injury in the hearts of transgenic mice ... Impaired autophagosome clearance contributes to cardiomyocyte death in ischemia/reperfusion injury. Circulation. 2012;125(25): ...
https://www.jci.org/articles/view/98287
*  Naringin Attenuates Cerebral Ischemia-Reperfusion Injury Through Inhibiting Peroxynitrite-Mediated Mitophagy Activation |...
... injury. Peroxynitrite (ONOO−), a representative reactive nitrogen species, mediates excessive mitophagy... ... Excessive autophagy/mitophagy plays important roles during cerebral ischemia-reperfusion (I/R) ... Winquist RJ, Kerr S (1997) Cerebral ischemia-reperfusion injury and adhesion. Neurology 49(5 Suppl 4):S23-S26CrossRefPubMed ... Cerebral ischemia-reperfusion injury Mitophagy Naringin Nitrative stress Peroxynitrite Electronic supplementary material. The ...
https://link.springer.com/article/10.1007/s12035-018-1027-7
*  Reperfusion injury - Wikipedia
Reperfusion injury or reperfusion insult, sometimes called ischemia-reperfusion injury (IRI) or reoxygenation injury, is the ... Reperfusion can cause hyperkalemia. Reperfusion injury is a primary concern in liver transplantation surgery. A study of aortic ... or what is termed reperfusion injuries. In fact an individual suffering from an ischemic insult continues suffering injuries ... Reperfusion injury plays a part in the brain's ischemic cascade, which is involved in stroke and brain trauma. Similar failure ...
https://en.wikipedia.org/wiki/Reperfusion_injury
*  Visualizing and targeting oxidative stress in hepatic ischemia-reperfusion injury
Ischemia-reperfusion (IR) injury is the inevitable result of liver resection performed using vascular inflow occlusion (VIO), ... Visualizing and targeting oxidative stress in hepatic ischemia-reperfusion injury. Supervisors. T.M. van Gulik. ... In addition, the protective effect of hypothermia on IR injury was investigated using a new method for in situ hypothermic ... Hepatocellular oxidative stress forms a pivotal aspect of IR injury, predominantly during the early (0-30 min) phase of ...
http://dare.uva.nl/search?identifier=f53b5a16-0615-450e-9ee7-33e0f5bff6f0
*  A New Light on the Mechanisms of Early Stage Liver Reperfusion Injury
Reperfusion of a previously ischemic tissue is associated with additional injury leading to structural and functional ... The injury induced during reperfusion is evolved a biphasic pattern consisting of an early stage started upon reoxygenation and ... Reperfusion of a previously ischemic tissue is associated with additional injury leading to structural and functional ... in the early stage of hepatic reperfusion injury and the presence of apoptotic bodies were augmented as the time of reperfusion ...
http://www.medindia.net/news/A-New-Light-on-the-Mechanisms-of-Early-Stage-Liver-Reperfusion-Injury-51079-1.htm