Ischemic-reperfusion injury. Rhizoma coptidis has therapeutic effects on ischemia-reperfusion injury by regulation of Akt/AMPK/ ... P38MAPK is crucial in myocardial ischemia and reperfusion [83]. Rhizoma coptidis also inhibits ischemia-reperfusion injury by ... A p38MAPK/MK2 signaling pathway leading to redox stress, cell death and ischemia/reperfusion injury. Cell Commun Signal CCS. ... Palmatine from Coptidis rhizoma reduces ischemia-reperfusion-mediated acute myocardial injury in the rat. Food Chem Toxicol. ...
Vitamin D ameliorates hepatic ischemic/reperfusion injury in rats. J Physiol Biochem. 2014;70:659-666. ... Injury enhances TLR2 function and antimicrobial peptide expression through a vitamin D-dependent mechanism. J Clin Invest. 2007 ...
Global cerebral ischemia followed by reperfusion, which leads to extensive neuronal damage, particularly the neurons in the ... Xu X, Chua CC, Gao J et al (2008) Neuroprotective effect of humanin on cerebral ischemia/reperfusion injury is mediated by a ... Wong GT, Li R, Jiang LL et al (2010) Remifentanil post-conditioning attenuates cardiac ischemia-reperfusion injury via kappa or ... Yuan Y, Guo Q, Ye Z et al (2011) Ischemic postconditioning protects brain from ischemia/reperfusion injury by attenuating ...
HIF-P4H-2 deficiency protects against skeletal muscle ischemia-reperfusion injury. J Mol Med 94:301-310 ... Even though fructose is also required to develop liver injury on the HF-MCD diet, which contains sucrose [48], this diet ... of hypoxia-inducible factor prolyl 4-hydroxylase-2 hypomorphic mice show protection against acute ischemia-reperfusion injury. ... Dietary sucrose is essential to the development of liver injury in the methionine-choline-deficient model of steatohepatitis. J ...
... reduces ischemia reperfusion injury in rat kidneys. J Cardiovasc Pharm 37:262-270 ... and renal arsenic accumulation were significantly decreased and reduced renal morphologic injury was observed compared with the ... and prolongs survival in a mouse model of sepsis-induced acute kidney injury. Kidney Int 81:370-378 ...
Short-term cardiac stress, induced by ischemia-reperfusion (I/R) injury resulted in impaired left ventricular (LV) recovery and ... Refined approach for quantification of in vivo ischemia-reperfusion injury in the mouse heart. Am J Physiol Heart Circ Physiol ... Cardiac-specific expression of heme oxygenase-1 protects against ischemia and reperfusion injury in transgenic mice. Circ Res ... Generation and release of Ly6Chi monocytes from the spleen of Hmox1−/− mice in response to cardiac injury. Previously, it was ...
2021). Macrophage scavenger receptor 1 (Msr1), also named Cd204, contribute to I/R injury when overexpressed; however, loss of ... Savitz SI, Baron J-C, Yenari MA et al (2017) Reconsidering neuroprotection in the reperfusion era. Stroke 48:3413-3419. https ... Dong R, Huang R, Wang J et al (2021) Effects of microglial activation and polarization on brain injury after stroke. Front ... Combinatory therapy in treating ischemic stroke is an attractive approach due to the multifaceted nature of the I/R injury. ...
conducted a randomized trial in 1,000 patients with ARDS or acute lung injury with the aim of comparing hemodynamic management ... The ReOx rate seen on reperfusion is an measure of both the limbs oxygen content and the capacity to recruit arterioles and ... Aggressive fluid resuscitation should be avoided and hypotension tolerated in trauma patients with penetrating injury-until the ... anaphylaxis or spinal injury). The features of each of these four types of shock often overlap, and patients admitted with one ...