"A homeodomain protein binds to gamma-globin gene regulatory sequences". Proceedings of the National Academy of Sciences of the ... Guazzi S, Pintonello ML, Viganò A, Boncinelli E (May 1998). "Regulatory interactions between the human HOXB1, HOXB2, and HOXB3 ... Shen WF, Krishnan K, Lawrence HJ, Largman C (Nov 2001). "The HOX homeodomain proteins block CBP histone acetyltransferase ... The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression ...

Gene Regulatory Networks * Homeodomain Proteins / genetics * Homeodomain Proteins / metabolism * In Situ Hybridization ... Oligonucleotide Array Sequence Analysis * POU Domain Factors / genetics * POU Domain Factors / metabolism ...

SATB1 is a homeodomain MAR binding protein. It recognizes ATC sequences that consist of stretches of As, Ts, and Cs on one ... Recently it has been reported that repression of SATB1 was essential for the phenotype and function of mouse regulatory T cells ... SATB1 is a homeodomain MAR binding protein. It recognizes ATC sequences that consist of stretches of As, Ts, and Cs on one ... Recently it has been reported that repression of SATB1 was essential for the phenotype and function of mouse regulatory T cells ...

... although the sequence and predicted secondarystructure do not resemble a homeodomain. The early general expression ofdri and ... and othermammalian regulatory proteins. A mouse B-cell-specific regulator exhibits75% identity with DRI over the 137-amino-acid ... Bright binds the minor groove of arestricted ATC sequence that is sufficient for nuclear matrix association.This sequence motif ... The domain within your query sequence starts at position 1058 and ends at position 1148; the E-value for the ARID domain shown ...

SATB1 is a homeodomain MAR binding protein. It recognizes ATC sequences that consist of stretches of As, Ts, and Cs on one ... Recently it has been reported that repression of SATB1 was essential for the phenotype and function of mouse regulatory T cells ... SATB1 is a homeodomain MAR binding protein. It recognizes ATC sequences that consist of stretches of As, Ts, and Cs on one ... Recently it has been reported that repression of SATB1 was essential for the phenotype and function of mouse regulatory T cells ...

Homeotic proteins have a gene regulatory function and use their homeodomains to recognize and bind to their target genes in ... Since Pax-6 is a transcription factor which basically can regulate any gene which has the appropriate regulatory sequences, ... Later we proved definitively that homeotic genes have a gene regulatory function and encode sequence specific DNA binding ... It was a long journey from antennal legs to the homeodomain at atomic resolution. If the homeobox had been found exclusively in ...

LMX1B encodes a LIM-homeodomain transcription factor. Mutations in LMX1B cause nail-patella syndrome (NPS), an autosomal ... We identified several LMX1B binding sites in the putative regulatory regions of both CD2AP and NPHS2 (podocin) and demonstrated ... LMX1B encodes a LIM-homeodomain transcription factor. Mutations in LMX1B cause nail-patella syndrome (NPS), an autosomal ... that LMX1B binds to these sequences in vitro and can activate transcription through them in cotransfection assays. Thus, LMX1B ...

The homeodomain (HD) is a sequence-specific DNA-binding domain (Desplan et al., 1988; Ekker et al., 1991; Hoey and Levine, 1988 ... A homeodomain substitution changes the regulatory specificity of the Deformed protein in Drosophila embryos ... Crystal structure of an engrailed homeodomain-DNA complex at 2.8 Å resolution, a framework for understanding homeodomain-DNA ... The distinct regulatory specificities of EFE and En are further seen in their divergent effects on wingless (wg) expression. ...

HAT3.1 is further characterized by an N-terminal region that shares substantial sequence similarity with the maize homeodomain ... HAT3.1 mRNA was primarily detected in root tissue, implying a regulatory function of this protein in root development. ... Plan homeodomain finger of tumour supressor ING4. 2ke1. Molecular Basis of non-modified histone H3 tail Recognition by the ... The plant homeodomain (PHD) finger is a C4HC3 zinc-finger-like motif found in nuclear proteins thought to be involved in ...

HAT3.1 is further characterized by an N-terminal region that shares substantial sequence similarity with the maize homeodomain ... HAT3.1 mRNA was primarily detected in root tissue, implying a regulatory function of this protein in root development. ... Plan homeodomain finger of tumour supressor ING4. 2ke1. Molecular Basis of non-modified histone H3 tail Recognition by the ... The plant homeodomain (PHD) finger is a C4HC3 zinc-finger-like motif found in nuclear proteins thought to be involved in ...

... dominant effects on cell shape and behavior and transcription factor activity suggest that Csl plays a role in the regulatory ... in a screen for transcriptional targets of the cardiac homeodomain factor Nkx2-5. Csl transcripts were detected in atria and ... Homeodomain Proteins, Insulin-Like Growth Factor I, MEF2 Transcription Factors, Mice, Mice, Knockout, Molecular Sequence Data, ... Aging, Amino Acid Sequence, Animals, Base Sequence, Calcineurin, Cell Differentiation, Cell Fusion, Cell Line, Cell Size, ...

... lycopersicum zinc-finger homeodomain) genes cluster into the same neighbor-joining (NJ) branch as arabidopsis, indicating that ... Members of the zinc-finger homeodomain (ZF-HD) family play a key role in the control of plant growth and development, which are ... an alignable nucleotide sequence covering over 70% of the longer sequence and identity between amino acid sequences over 70% ( ... have been shown to play important roles in the regulatory networks of numerous developmental processes in plants. The first TF ...

The amino acid sequences of Duxbl homeodomains are most similar to those of human DUX4 protein, associated with ... We suggest that Duxbl proteins play regulatory roles during myogenesis and reproductive developments. ... The amino acid sequences of Duxbl homeodomains are most similar to those of human DUX4 protein, associated with ... The amino acid sequences of Duxbl homeodomains are most similar to those of human DUX4 protein, associated with ...

Cis-regulatory rewiring promoted B-ALL-specific gene regulatory networks impacting oncogenic signaling pathways that perturb ... Clinical G6PD genotyping is now included in pharmacogenetic arrays and clinical sequencing efforts and may be reconciled with ... Among ALL subtypes, we uncovered roles for basic helix-loop-helix, homeodomain and activator protein 1 transcription factors in ... To address this, we mapped the gene regulatory response to GCs in two ALL cell lines using functional genomics and high- ...

report the sequence of the genetically tractable species Schizophyllum commune and identify genes involved in the formation of ... A homeodomain gene has also been identified previously in the Aβ locus of H4-8 (ref. 11). Our genomic sequence revealed that ... and regulatory mechanisms (such as transcriptional regulation by transcription factors and signal transduction by G-protein α ... The genome sequence of S. commune reveals four additional genes with high sequence similarity to these pheromone receptor genes ...

The ncRNA regulatory network in asthmatic ASMCs. The study of ncRNAs in ASMCs has focused on three core regulatory axes, the " ... Lin et al. [128] and Jiang et al. [129] both confirmed that circular homeodomain interacting protein kinase 3 (circHIPK3) is ... next-generation sequencing identified miR-10a as the miRNA expressed most abundantly in primary human ASMCs [9]. MiR-10a ... We propose building an ncRNA regulatory network based on three classic regulatory patterns to help us better understand ncRNAs ...

All homeotic genes share a segment of protein with a similar sequence and structure called the homeodomain (the DNA sequence is ... The homeodomain ... Both the regulatory protein and the morphogenic protein are involved in the development of the tail segment ... Antennapedia Homeodomain ProteinHomeodomain ProteinsGenes, HomeoboxTranscription FactorsNuclear ProteinsMolecular Sequence Data ... some differences in nucleotide sequences and in the deduced homeodomain amino acid sequences compared with the sequences that ...

... patterning and differentiation processes by binding in a sequence-specific manner to the DNA, mediated by the homeodomain, thus ... Does the high gene density in the sponge NK homeobox gene cluster reflect limited regulatory capacity? Biol Bull. 2008;214(3): ... Expression of an NK2 homeodomain gene in the apical ectoderm defines a new territory in the early sea urchin embryo. Dev Biol. ... 1) [27]. In this study, we used the previously identified NKL sequences to generate specific probes and conducted in situ ...

A map of the cis-regulatory sequences in the mouse genome. Nature 488, 116-120 (2012). ... The LIM homeodomain factor Lhx2 is required for hypothalamic tanycyte specification and differentiation. J. Neurosci. 34, 16809 ... Sequencing was carried out on the HiSeq 4000 (Illumina), with 28 cycles for sequencing read 1, 8 cycles for index read 1, and ... ATAC sequencing. ATAC sequencing libraries were prepared using the OMNI-ATAC protocol71 with minor modifications:. 25,000 MACS- ...

PDB Compounds: (A:) Transcription regulatory protein SWI3. SCOP Domain Sequences for d2fq3a1:. Sequence; same for both SEQRES ... Superfamily a.4.1: Homeodomain-like [46689] (17 families) consists only of helices. ... Protein Transcription regulatory protein swi3 [140223] (1 species). *. Species Bakers yeast (Saccharomyces cerevisiae) [TaxId: ... PDB Description: Structure and function of the SWIRM domain, a conserved protein module found in chromatin regulatory complexes ...

Furthermore, in transcripts of both Brd and m4 there are three common regulatory sequence motifs within the 3 UTR. These are ... All genes in the ANTP-C and BX-C code for homeodomain proteins. Together, they regulate the segment identity of the fly. Genes ... Thus, it is suggested that evolution of transcriptional cis-regulatory sequences has been a major mechanism for diversification ... regulatory sequences (Cooper, 2000). The factors that modulate the responsiveness of the enhancers to Su(H)/Nicd and activators ...

The target sequence of the siRNA is 5-TGATCAGCCTCAATCTGCA-3 for human δEF1 as previously reported [36]. The sense and ... δEF1, a member of the zinc finger-homeodomain family of transcription factors [30, 31], was originally identified as a binding ... Kamachi Y, Kondoh H: Overlapping positive and negative regulatory elements determine lens-specific activity of the delta1- ... Dillner NB, Sanders MM: The zinc finger/homeodomain protein δEF1 mediates estrogen-specific induction of the ovalbumin gene. ...

We have performed a promoter analysis searching for potential regulatory sequences of puc and identified different specific ... Transcription factors (TFs) in the homeodomain-leucine zipper (HD-ZIP) family serve as essential regulators of plant ... The sequence was compared with accession #NC-012920.1 of the revised Cambridge Reference Sequence (rCRS). (3) Results: The ... In other words, the DNA sequence is converted into a numeral bit sequence that makes it possible to implement the blockchain ...

These brief peptide sequences in the antigen are often presented over the cell surface area of APCs by using MHCII substances, ... WUSCHEL, a stem cell-promoting homeodomain transcription element, accumulates at a higher level in the rib meristem than in the ... Studies suggest that this regulatory challenge is solved by the activity of the so-called sub-temporal genes, which act in ... Furthermore, we show that the same WUSCHEL-box functions Cl-C6-PEG4-O-CH2COOH as a degron sequence Cl-C6-PEG4-O-CH2COOH in ...

For this purpose, residue scanning of the HOX minimal active sequence was performed to select the mutations to be further ... Variation in Homeodomain DNA Binding Revealed by High-Resolution Analysis of Sequence Preferences. Cell 2008, 133, 1266-1276. [ ... McGinnis, N.; Kuziora, M.A.; McGinnis, W. Human Hox-4.2 and Drosophila Deformed encode similar regulatory specificities in ... Stevens, K.E.; Mann, R.S. A Balance Between Two Nuclear Localization Sequences and a Nuclear Export Sequence Governs ...

... as well as the PCR items had been phylogenetically sequenced and sequences analyzed. LEADS TO the blood examples from pigs in ... WUSCHEL, a stem cell-promoting homeodomain transcription element, accumulates at a higher level in the rib meristem than in the ... To discriminate between both of these models, we slice the connection between your Pand the upstream regulatory cascade by ... NI sequenced the pandemic H1N1 strains and participated in examining the info and in drafting the manuscript. AH participated ...

transcription regulatory region sequence-specific DNA binding. ENSACAP00000010150. GO:0003677. molecular_function. DNA binding ... Homeodomain, metazoa. ENSACAP00000010150. PRINTS. PR00024. IPR020479. 197. 207. 1.30e-05. Homeodomain, metazoa. ...

","26S protease regulatory subunit 6A-like protein","protein_coding" "lcl,LHPG02000016.1_cds_PRW33666.1_3371","PRW33666"," ... ","Homeodomain","protein_coding" "lcl,LHPG02000012.1_cds_PRW45256.1_1828","PRW45256","Chlorella sorokiniana","Hypothetical ... "sequence_id","alias","species","description","type" "Cpa,evm.model.tig00000042.241","tig00000042_g15643.t1","Cyanophora ... ","26S proteasome non-ATPase regulatory subunit 11","protein_coding" "lcl,VRMN01000002.1_cds_KAA8496386.1_115","KAA8496386"," ...

","transcription regulatory protein SNF2, putative","protein_coding" "AT2G46410","CPC","Arabidopsis thaliana","Homeodomain-like ... "sequence_id","alias","species","description","type" "AT1G01570","No alias","Arabidopsis thaliana","Protein of unknown function ... ","sequence-specific DNA binding;sequence-specific DNA binding transcription factors","protein_coding" "AT4G03100","No alias"," ... ","Homeodomain-like protein with RING/FYVE/PHD-type zinc finger domain","protein_coding" "AT3G19700","IKU2","Arabidopsis ...