Dive into the research topics of Human skin mast cells adhere to vitronectin via the αvβ3 integrin receptor (CD51/CD61) [1]. ... Human skin mast cells adhere to vitronectin via the αvβ3 integrin receptor (CD51/CD61) [1]. ...
Felding-Habermann B, Cheresh DA (Oct 1993). "Vitronectin and its receptors". Current Opinion in Cell Biology. 5 (5): 864-8. doi ... Preissner KT, Seiffert D (Jan 1998). "Role of vitronectin and its receptors in haemostasis and vascular remodeling". Thrombosis ... In addition, vitronectin is a component of platelets and is, thus, involved in hemostasis. Vitronectin contains an RGD (45-47) ... Vitronectin has been speculated to be involved in hemostasis and tumor malignancy. Vitronectin is a 54 kDa glycoprotein, ...
Receptors, Vitronectin / immunology* * Receptors, Vitronectin / metabolism * Tumor Necrosis Factor-alpha / biosynthesis* * ...
In this study, we identified the integrin receptors that media … ... Vitronectin is expressed in a cell-specific manner in the developing brain and concentrated in the brain during disease ... In this study, we identified the integrin receptors that mediate attachment of primary neonatal rat astrocytes to vitronectin. ... Using fluorescent activated cell sorter and immunoprecipitation analyses, we established that the vitronectin receptor ...
The ITGB3 gene provides instructions for making the beta3 subunit of a receptor protein called integrin alphaIIb/beta3 (αIIbβ3 ... vitronectin receptor beta chain. Additional Information & Resources. Tests Listed in the Genetic Testing Registry. *Tests of ... The ITGB3 gene provides instructions for making the beta3 subunit of a receptor protein called integrin alphaIIb/beta3 (αIIbβ3 ...
Vitronectin receptor; Vitronectin receptor subunit alpha Gene Aliases: BDPLT16; BDPLT2; CD51; CD61; GP3A; GPIIIa; GT; ITGAV; ... vitronectin receptor, alpha polypeptide, antigen CD51); integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61); Platelet ... virus receptor activity opsonin binding fibronectin binding protease binding protein kinase C binding voltage-gated calcium ... The CD51/CD61 complex mediates adhesion to fibrinogen, fibronectin, vitronectin and thrombospondin.. Applications Reported: ...
Ligand/Receptor Fibronectin, vitronectin, vWF Cell Type Fibroblasts, Megakaryocytes, Osteoclasts, Platelets Biology Area ...
Identification of the urokinase receptor as an adhesion receptor for vitronectin. . J Biol Chem ... While mineralocorticoid receptor antagonists have shown some favorable results in renoprotection, the side effect of ... The antiproteinuric effect has been related to its inhibition of podocyte urokinase plasminogen activator receptor (uPAR) ... Amiloride, a urokinase-type plasminogen activator receptor (uTPA) inhibitor, reduces proteinuria in podocytes ...
... as well as vitronectin and laminin (4). However, AGE engagement of cellular receptors would provide a biologic amplification ... Multiligand receptors * Is the class A macrophage scavenger receptor (SR-A) multifunctional? - The mouses tale Nick Platt et ... Scavenger receptor class B type I is a multiligand HDL receptor that influences diverse physiologic systems Monty Krieger ... Krieger, M, Herz, J. Structures and functions of multiligand lipoprotein receptors: macrophage scavenger receptors and LDL ...
As such, it is a receptor for FIBRINOGEN; VON WILLEBRAND FACTOR; FIBRONECTIN; VITRONECTIN; and THROMBOSPONDINS. A deficiency of ... Receptors, Cytoadhesin [D12.776.543.750.705.408.460]. *Platelet Glycoprotein GPIIb-IIIa Complex [D12.776.543.750.705.408. ... Sex-specific platelet activation through protease-activated receptor-1 in patients undergoing cardiac catheterization. ... Shear-Mediated Platelet Microparticles Demonstrate Phenotypic Heterogeneity as to Morphology, Receptor Distribution, and ...
Phagocytosis is a term coined from the Greek to describe the receptor-mediated engulfment and degradation of dead cells and ... Phagocytosis is a term coined from the Greek to describe the receptor-mediated engulfment and degradation of dead cells and ... toll-like receptor; TREM2, triggering receptor expressed on myeloid cells 2; VnR, vitronectin receptor. ... receptors, integrin receptors, Ig superfamily-receptors, and scavenger and related receptors. For more details on the receptors ...
... known as poliovirus receptor (PVR) or nectin-like 5, is a 70 kD type I transmembrane glycoprotein. ... Ligand/Receptor CD226, CD96, nectin-1, -2, and -3, vitronectin, CD155, poliovirus Cell Type Endothelial cells, Epithelial cells ... Poliovirus receptor (PVR), nectin-like 5 Isotype Mouse IgG1, κ Ave. Rating Submit a Review Product Citations publications U937 ... and vitronectin. It also serves as a receptor for poliovirus and cytomegalovirus. ...
An adhesion receptor for vitronectin," The Journal of Biological Chemistry, vol. 265, no. 19, pp. 11008-11013, 1990. ... H. Konishi, S. Kuroda, Y. Inada, and Y. Fujisawa, "Novel subtype of human angiotensin II type 1 receptor: cDNA cloning and ... and subtypes of the angiotensin receptors [7-9]. Preeclampsia (PE) is a pregnancy associated disorder characterized by ... for finding and sequencing new genes and has been used to identify and clone transporters and receptors, such as human growth ...
Synonyms: vitronectin receptor alpha polypeptide (VNRA), CD51, alphav-integrin, 1110004F14Rik, 2610028E01Rik, D430040G12Rik ... Name: olfactory receptor family 12 subfamily J member 5. Synonyms: GA_x6K02T2PBJ9-42653501-42652578, MOR252-1, MOR252-4, ...
... which interact with receptors on the cell surface such as cytokine receptors, PPRs, and TNF receptor (TNFR) superfamily members ... Endothelial P- and E-selectins, adhesion molecule ICAM-1, vWF, and vitronectin allow the adhesion of platelets to the ... Its receptor contains a Toll-IL-1-receptor domain and plays a key role in the innate immune system. The main circulating form ... Macrophages express on their surface scavenger receptors (SR) such as CD36, SR-A1, and lectin-like oxLDL receptor-1 (LOX-1) ...
... rather than by the receptor-mediated adhesion through serum-derived proteins adsorbed on the PPs. ... The extracellular parts of these receptors bind the ECM proteins (e.g., vitronectin, fibronectin), adsorbed on the studied ... It was attributed to binding of cells to glycated collagen through αvβ3 integrin adhesion receptors instead of the α2β1 ... Despite this, we observed that all the cell types were capable of specific receptor-mediated adhesion on the studied surfaces, ...
Structure of urokinase receptor, urokinase and vitronectin complex. 3bt2. Structure of urokinase receptor, urokinase and ... Low-density lipoprotein receptor (P01130) (SMART). OMIM:143890: Hypercholesterolemia, familial. Coagulation factor IX (P00740 ... Structural basis for specific recognition of reelin by its receptors. 3asi. Alpha-Neurexin-1 ectodomain fragment; LNS5-EGF3- ... Structure of the extracellular domain of human epidermal growth factor (EGF) receptor in an inactive (low pH) complex with EGF. ...
Structure of urokinase receptor, urokinase and vitronectin complex. 3bt2. Structure of urokinase receptor, urokinase and ... Low-density lipoprotein receptor (P01130) (SMART). OMIM:143890: Hypercholesterolemia, familial. Coagulation factor IX (P00740 ... Structural basis for specific recognition of reelin by its receptors. 3asi. Alpha-Neurexin-1 ectodomain fragment; LNS5-EGF3- ... Structure of the extracellular domain of human epidermal growth factor (EGF) receptor in an inactive (low pH) complex with EGF. ...
... vitronectin receptor; 27) but also αvβ1, αvβ5 (28, 29) and the hyaluronic acid receptor CD44 (30) and/or its variants (31). It ... OPN binds to cells via the vitronectin receptor (αvβ3 integrin; Ref. 27) but also via other integrins and the hyaluronic acid ... Distinct conformations of vitamin D receptor/retinoid X receptor-α heterodimers are specified by dinucleotide differences in ... Weber G. F., Ashkar S., Glimcher M. J., Cantor H. Receptor-ligand interaction between CD44 and osteopontin (η-1). Science (Wash ...
... and vitronectin. Approximately 80,000 GP IIb-IIIa receptors are present on the surface of each platelet. GP IIb and GP IIIa ... Abnormalities in either gene or in the assembly of the complex result in an abnormal or deficient receptor and, consequently, ... Biogenesis of the platelet receptor for fibrinogen: evidence for separate precursors for glycoproteins IIb and IIIa. Proc Natl ...
CD38 and vitronectin receptor (αvβ3 integrin, CD51/CD61) are proposed to be ligands for CD31. CD31-mediated endothelial cell- ... CD38 and vitronectin receptor (αvβ3 integrin, CD51/CD61) are proposed to be ligands for CD31. CD31-mediated endothelial cell- ... CD38 and vitronectin receptor (αvβ3 integrin, CD51/CD61) are proposed to be ligands for CD31. CD31-mediated endothelial cell- ... Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis. Cell. 1996; 87(7):1171-1180. ( ...
Among the proteins from tumor stroma, the protein ITGAV is a receptor of ECM and serves as a subunit for receptors of integrins ... RGD-motif bound containing substrates, such as vitronectin, fibronectin and fibrinogen, which are components of the stroma ...
Novel vascular lesions in mice given a non-peptide vitronectin receptor antagonist. Toxicol Pathol. 2007;35:958-71. (IHC-PS) ... FCRL5 exerts binary and compartment-specific influence on innate-like B-cell receptor signaling. Proc Natl Acad Sci USA. 2013; ... FcμR interacts and cooperates with the B cell receptor To promote B cell survival. J Immunol. 2015;194:3096-101. (IP) ... BAFF controls neural cell survival through BAFF receptor. PLoS One. 2013;8(7):e70924. (IHC-FS) ...
The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein. This ...
"The Vitronectin Receptor and its Associated CD47 Molecule Mediates Proinflammatory Cytokine Synthesis in Human Monocytes by ... CD47 is a 50 kDa membrane receptor that has extracellular N-terminal IgV domain, five transmembrane domains, and a short C- ... 1996). "Integrin-associated protein is a receptor for the C-terminal domain of thrombospondin". J. Biol. Chem. 271 (1): 21-4. ... Sick E, Boukhari A, Deramaudt T, Rondé P, Bucher B, André P, Gies JP, Takeda K (February 2011). "Activation of CD47 receptors ...
Signaling through Notch receptors in the skin has been implicated in the differentiation, proliferation, and survival of ... Arnt-/- and Hifα-/- TS cells exhibit reduced adhesion and migration toward vitronectin compared with wild-type cells. ... HIF is a heterodimeric transcription factor consisting of α and ß aryl hydrocarbon receptor nuclear translocator or ARNT) ... the composite function of Notch receptor-mediated signaling in the skin and overcome potential redundancies between receptors, ...
Breast cancer tissue highly expresses the chemokine receptor, chemokine (C-X-C motif) receptor 4 (CXCR4) while its ligand, ... fibrinogen and vitronectin (22). Invasion is preceded by degradation of the ECM to enable the penetration of tissue boundaries ... VEGF receptor signalling - in control of vascular function. Nat Rev Mol Cell Biol 7: 359-371, 2006. ... MMP9 induction by vascular endothelial growth factor receptor-1 is involved in lung-specific metastasis. Cancer Cell 2: 289-300 ...
... vitronectin receptor; Article; cheek cell; controlled study; enzyme linked immunosorbent assay; fibroblast; human; human cell; ... Receptors, Vitronectin; Sensitivity and Specificity; Thrombin; Transforming Growth Factor beta1. [SDGs]SDG3. ... vitronectin receptor; alphaVbeta5 integrin; catechin; epigallocatechin gallate; integrin alphavbeta1; thrombin; transforming ... Results: Thrombin and protease-activated receptor-1 (PAR-1) agonist induced TGF-β1 activation and Smad3 phosphorylation. ...
The role of the integrin vitronectin receptor, alpha v beta 3 in melanoma metastasis. Cancer Metastasis Rev 14(3): 241-252, ... Alcohol-sensitive GABA receptors and alcohol antagonists. Proc Natl Acad Sci USA 103(22): 8307-8308, 2006. ... Mammary tumorigenesis and metastasis caused by overexpression of insulin receptor substrate 1 (IRS-1) or IRS-2. Mol Cell Biol ... Ethanol reduces available IL-6, which lowers IL-6 receptor activation in melanoma cells. This may lead to lower NF-kB ...