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*  Status Epilepticus Induces a Particular Microglial Activation State Characterized by Enhanced Purinergic Signaling | Journal of...
2000) Activation of mouse microglial cells affects P2 receptor signaling. Brain Res 853:49-59. ... Increased expression of purinergic receptor mRNAs in the hippocampus after status epilepticus. Activation of purinergic ... and P2Y13 purinergic receptors. This specific set of receptors has been selected on the basis of previous studies that have ... Quantitative PCR of purinergic receptors in whole hippocampi from control animals (n = 4) and from treated animals at 3 (n = 4 ...
http://www.jneurosci.org/content/28/37/9133.long
*  Implications of purinergic receptor-mediated intracellular calcium transients in neural differentiation | Cell Communication...
Dubyak GR, El-Moatassim C: Signal transduction via P2-purinergic receptors for extracellular ATP and other nucleotides. Am J ... Intracellular calcium signaling and purinergic receptors. *Purinergic receptors triggering ICS in the nervous system and neural ... purinergic receptors are divided into metabotropic P1 and P2Y receptors as well as P2X ionotropic receptors. ... Oscillations of [Ca 2+ ] i levels and purinergic receptors. Ionotropic P2X receptors trigger calcium spikes characterized by ...
https://biosignaling.biomedcentral.com/articles/10.1186/1478-811X-11-12
*  The Role of Uridine Adenosine Tetraphosphate in the Vascular System
D. Erlinge and G. Burnstock, "P2 receptors in cardiovascular regulation and disease," Purinergic Signalling, vol. 4, no. 1, pp ... Purinoceptors have been classified into two subtypes (namely, P1 receptors (or adenosine receptors) and P2 receptors) based on ... The P2 receptors exist in two major families: ionotropic (P2X receptors) and metabotropic (P2Y receptors) [26-30]. Currently, ... P2X receptor) and G protein-coupled receptor (e.g., P2Y receptor and adenosine receptor) participate in multiprotein complexes ...
https://www.hindawi.com/journals/aps/2011/435132/
*  Antiplatelet Effects of Ticagrelor Versus Clopidogrel in American Indian Patients - Full Text View - ClinicalTrials.gov
Purinergic P2Y Receptor Antagonists. Purinergic P2 Receptor Antagonists. Purinergic Antagonists. Purinergic Agents. ... Purinergic P2Y Receptor Antagonists. Purinergic P2 Receptor Antagonists. Purinergic Antagonists. Purinergic Agents. ... Compare ticagrelor's versus clopidogrel's inhibition of the P2Y12 receptor as measured by the decrease in P2Y12 Reaction Units ...
https://clinicaltrials.gov/ct2/show/NCT01706510?recr=Open&intr=%22Platelet+Aggregation+Inhibitors%22&rank=11
*  Purinergic receptors expressed in human skeletal muscle fibres | SpringerLink
Purinergic receptors are present in most tissues and thought to be involved in various signalling pathways, including neural ... Erlinge D, Burnstock G (2008) P2 receptors in cardiovascular regulation and disease. Purinergic Signal 4:1-20PubMedCrossRef ... ATP stimulates glucose transport through activation of P2 purinergic receptors in C2C12 skeletal muscle cells. Arch Bioch ... Burnstock G (2004) Introduction: P2 receptors. Curr Top Med Chem 4:793-803PubMedCrossRefGoogle Scholar ...
https://link.springer.com/article/10.1007%2Fs11302-011-9279-y
*  ATP-Evoked Sustained Vasoconstrictions Mediated by Heteromeric P2X1/4 Receptors in Cerebral Arteries | Stroke
P2 receptors in cardiovascular regulation and disease. Purinergic Signal. 2008;4:1-20. ... The P2 receptor antagonist PPADS supports recovery from experimental stroke in vivo. PLoS One. 2011;6:e19983. ... Neuroprotective effects of the P2 receptor antagonist PPADS on focal cerebral ischaemia-induced injury in rats. Eur J Neurosci ... Vascular smooth muscle cells from small human omental arteries express P2X1 and P2X4 receptor subunits. Purinergic Signal. In ...
http://stroke.ahajournals.org/content/45/8/2444
*  COA of Suramin sodium salt | Certificate of Analysis | AbMole BioScience
... and non-selectively antagonizes P2 purinergic receptors (10-100 μM).. ... salt is a polysulfonated naphthylurea that inhibits the binding of calmodulin to recognition sites on the ryanodine receptor-1 ...
http://www.abmole.com/literature/suramin-sodium-salt-coa.html
*  Positive Inotropic Effects by Uridine Triphosphate (UTP) and Uridine Diphosphate (UDP) via P2Y2 and P2Y6 Receptors on...
Vassort G. Adenosine 5′-triphosphate: a P2-purinergic agonist in the myocardium. Physiol Rev. 2001; 81: 767-806. ... P2 receptors), which is one of the largest known receptor families.10 P2 receptors are divided into two classes: ligand-gated ... Finally, expression of pyrimidine-selective receptors (a subgroup of the P2 receptors) was studied in human and mouse heart, ... we used real-time PCR to quantify the mRNA expression of P2 receptors in heart tissue from man and mouse. The P2Y2 receptor was ...
http://circres.ahajournals.org/content/98/7/970
*  Age-related changes in P2-purinergic receptors on vascular smooth muscle and endothelium. | Hypertension
Age-related changes in P2-purinergic receptors on vascular smooth muscle and endothelium.. T Koga, Y Takata, K Kobayashi, K ... In contrast, a P2-purinergic receptor leading to the generation of endothelium-derived relaxing factor may be activated in ... This suggests that the vascular smooth muscle of young rats has a P2-purinergic receptor leading to relaxation and that this ... The alterations with age of P2-purinergic receptor in the vascular smooth muscle and endothelial cell are not affected by ...
http://hyper.ahajournals.org/content/19/3/286
*  Gap junction and purinergic P2 receptor proteins as a functional unit: insights from transcriptomics
Gap junctions and purinergic P2 receptors (P2Rs) can be regarded as belonging to a common functional unit, given that they are ... Gap junction and purinergic P2 receptor proteins as a functional unit: insights from transcriptomics. Domenii publicaţii > ... including purinergic receptors (P2Rs), and have found that genes synergistically or antagonistically expressed in wild-type ... genes encode proteins that are components of P2R signal-transduction pathways and/or directly interact with these receptors, ...
http://ad-astra.ro/2008/07/27/gap-junction-and-purinergic-p2-receptor-proteins-as-a-functional-unit-insights-from-transcriptomics/
*  Enkephalin activates the phospholipase C/Ca2+ system through cross-talk between opioid receptors and P2-purinergic or...
In an NG 108-15 neuroblastoma x glioma hybrid cell suspension, extracellular ATP (via P2-purinergic receptors) and bradykinin ... Enkephalin activates the phospholipase C/Ca2+ system through cross-talk between opioid receptors and P2-purinergic or ... Enkephalin activates the phospholipase C/Ca2+ system through cross-talk between opioid receptors and P2-purinergic or ... Enkephalin activates the phospholipase C/Ca2+ system through cross-talk between opioid receptors and P2-purinergic or ...
http://www.biochemj.org/content/290/1/241?ijkey=d35e49735fff05ea5e01814bb56341bcc6afacb2&keytype2=tf_ipsecsha
*  P2 purinergic receptor modulation of cytokine production - pdf descargar
P2 purinergic receptor modulation of cytokine production. . Biblioteca virtual para leer y descargar libros, documentos, ... P2 purinergic receptor modulation of cytokine production - Descarga este documento en PDF. Documentación en PDF para descargar ... and these cells also express numerous members of the purinergic P2 receptor family. Studies in several cellular systems have ... These examples demonstrate important roles of purinergic receptors in the modulation of cytokine production. Extension of these ...
http://libros.duhnnae.com/2017/jul3/149894748662-P2-purinergic-receptor-modulation-of-cytokine-production.php
*  Plus it
The P2 purinergic receptors comprise seven P2X receptor subunits (P2X1-7), which are ligand-gated ion channels (North, 2002), ... Hippocampal neurons express both P2X and P2Y purinergic receptors. PPADS is a nonselective (but nonuniversal) P2 receptor ... Extracellular ATP plays an important role in cellular signaling via P2 type-purinergic receptors (Kanjhan et al., 1996), which ... Furthermore, we found that the protective role of ATP is mediated by the P2 purinergic receptor signaling pathway. Together, ...
http://www.jneurosci.org/content/32/9/3081
*  Reversal of Dual Antiplatelet Therapy With Cold Stored Platelets - Full Text View - ClinicalTrials.gov
Purinergic P2Y Receptor Antagonists. Purinergic P2 Receptor Antagonists. Purinergic Antagonists. Purinergic Agents. ...
https://clinicaltrials.gov/ct2/show/NCT03787927?term=platelet&
*  Is There A LIfe for Drug Eluting Stent (DES) After Discontinuation of Clopidogrel - Full Text View - ClinicalTrials.gov
Purinergic P2Y Receptor Antagonists. Purinergic P2 Receptor Antagonists. Purinergic Antagonists. Purinergic Agents. ...
https://clinicaltrials.gov/ct2/show/NCT01476020
*  Different LD of Ticagrelor for Antiplatelet Effect in Patients With Non-ST-segment Elevation ACS Undergoing PCI - Full Text...
Purinergic P2Y Receptor Antagonists. Purinergic P2 Receptor Antagonists. Purinergic Antagonists. Purinergic Agents. ... Vasodilator-stimulated phosphoprotein(VASP) phosphorylation, a measure of P2Y12 receptor reactivity, was determined by flow ...
https://clinicaltrials.gov/ct2/show/NCT01962428?term=angina&lup_s=10%2F18%2F2013&lup_d=14&show_rss=Y&sel_rss=mod14
*  Optimizing Aspirin and Clopidogrel Therapy (BOchum CLopidogrel and Aspirin Plan) - Full Text View - ClinicalTrials.gov
Purinergic P2Y Receptor Antagonists. Purinergic P2 Receptor Antagonists. Purinergic Antagonists. Purinergic Agents. ...
https://clinicaltrials.gov/ct2/show/NCT01212302
*  Association of Clopidogrel Therapy and Stent Thrombosis - Full Text View - ClinicalTrials.gov
Purinergic P2Y Receptor Antagonists. Purinergic P2 Receptor Antagonists. Purinergic Antagonists. Purinergic Agents. ...
https://clinicaltrials.gov/ct2/show/NCT00484926
*  Antiplatelet Effects of Ticagrelor Versus Clopidogrel in American Indian Patients - Full Text View - ClinicalTrials.gov
Purinergic P2Y Receptor Antagonists. Purinergic P2 Receptor Antagonists. Purinergic Antagonists. Purinergic Agents. ... Purinergic P2Y Receptor Antagonists. Purinergic P2 Receptor Antagonists. Purinergic Antagonists. Purinergic Agents. ... Compare ticagrelor's versus clopidogrel's inhibition of the P2Y12 receptor as measured by the decrease in P2Y12 Reaction Units ...
https://clinicaltrials.gov/ct2/show/NCT01706510?term=%22native+american%22+OR+%22american+indian%22&recr=Open&rank=7
*  Trial of Cilostazol in Symptomatic Intracranial Arterial Stenosis II - Full Text View - ClinicalTrials.gov
Purinergic P2Y Receptor Antagonists. Purinergic P2 Receptor Antagonists. Purinergic Antagonists. Purinergic Agents. ...
https://clinicaltrials.gov/ct2/show/NCT00130039
*  Study to Assess Safety and Efficacy of Ticagrelor (AZD6140) Versus Clopidogrel in Asian/Japanese Patients With Non-ST or ST...
Purinergic P2Y Receptor Antagonists. Purinergic P2 Receptor Antagonists. Purinergic Antagonists. Purinergic Agents. ...
https://clinicaltrials.gov/show/NCT01294462