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*  Purinergic receptors expressed in human skeletal muscle fibres | SpringerLink
Purinergic receptors are present in most tissues and thought to be involved in various signalling pathways, including neural ... Erlinge D, Burnstock G (2008) P2 receptors in cardiovascular regulation and disease. Purinergic Signal 4:1-20PubMedCrossRef ... Purinergic receptors are present in most tissues and thought to be involved in various signalling pathways, including neural ... P2X receptor expression in mouse urinary bladder and the requirement of P2X1 receptors for functional P2X receptor responses in ...
https://link.springer.com/article/10.1007%2Fs11302-011-9279-y
*  Gap junction and purinergic P2 receptor proteins as a functional unit: insights from transcriptomics
Gap junctions and purinergic P2 receptors (P2Rs) can be regarded as belonging to a common functional unit, given that they are ... Gap junction and purinergic P2 receptor proteins as a functional unit: insights from transcriptomics. Domenii publicaţii > ... including purinergic receptors (P2Rs), and have found that genes synergistically or antagonistically expressed in wild-type ... genes encode proteins that are components of P2R signal-transduction pathways and/or directly interact with these receptors, ...
http://ad-astra.ro/2008/07/27/gap-junction-and-purinergic-p2-receptor-proteins-as-a-functional-unit-insights-from-transcriptomics/
*  The Role of Uridine Adenosine Tetraphosphate in the Vascular System
A. Surprenant and R. Alan North, "Signaling at purinergic P2X receptors," Annual Review of Physiology, vol. 71, pp. 333-359, ... P2X receptor) and G protein-coupled receptor (e.g., P2Y receptor and adenosine receptor) participate in multiprotein complexes ... Purinoceptors have been classified into two subtypes (namely, P1 receptors (or adenosine receptors) and P2 receptors) based on ... P2Y receptors) [26-30]. Currently, there are at least 7 cloned P2X receptors and at least 8 cloned P2Y receptors [15-18, 21, 25 ...
https://www.hindawi.com/journals/aps/2011/435132/
*  Plus it
1995) P2-purinergic receptors: Subtype-associated signaling responses and structure. Annu Rev Pharmacol Toxicol 35:541-579. ... 1998) Metabotropic receptors for ATP and UTP: Exploring the correspondence between native and recombinant nucleotide receptors. ... Apart from uridine nucleotide-sensitive P2Y receptors (Boehm, 1998) and B2 bradykinin receptors (Jones et al., 1995), M1 ... the P2Y6-like receptors activated by UTP are the first example of GI- and/or Go-coupled receptors that trigger transmitter ...
http://molpharm.aspetjournals.org/content/57/6/1165
*  Vickery Trinkaus-Randall | School of Medicine
Minns MS, Trinkaus-Randall V. Purinergic Signaling in Corneal Wound Healing: A Tale of 2 Receptors. J Ocul Pharmacol Ther. 2016 ... These include but are not limited to glutamatergic and purinergic receptor-mediated calcium transients. 2. In addition to these ... Epithelial wounds induce differential phosphorylation changes in response to purinergic and EGF receptor activation. Am J ... when epithelial cells are injured nucleotides are released immediately and cause a distinct phosphorylation of EGF receptor ...
https://www.bumc.bu.edu/busm/profile/vickery-trinkaus-randall/
*  Suramin in Autism Treatment
Suramin inhibits the binding of ATP and similar molecules to key purinergic receptors, according to Naviaux. It silences the ...
http://www.gordonmedical.com/unravelling-complex-chronic-illness/tag/suramin-in-autism-treatment/
*  Plus it
Coutinho-Silva R, Alves LA, Campos de Carvalho AC, Savino W, and Persechini PM. Characterization of P2Z purinergic receptors on ... Schilling WP, Wasylyna T, Dubyak GR, Humphreys BD, and Sinkins WG. Maitotoxin and P2Z/P2X7 purinergic receptor stimulation ... The receptor implicated in that phenomenon was later identified as the P2Z receptor on the basis of its unique properties: 1) ... Pro) Renin Receptor Mediates Albumin Induced Cellular Responses: Role of Site-1 Protease-Derived Soluble (Pro) Renin Receptor ...
http://ajpcell.physiology.org/content/288/2/C260
*  Purinergic activation of a leak potassium current in freshly diss...: Ingenta Connect
Purinergic agonists including dATP, but not ADP, activated the delayed K+ current, indicating that P2Y11 is the likely receptor ... We investigated the receptor, the intracellular pathway and the nature of this current. Methods: The patch-clamp technique was ... Purinergic activation of a leak potassium current in freshly dissociated myocytes from mouse thoracic aorta ...
http://www.ingentaconnect.com/content/bsc/aps/2009/00000195/00000002/art00005
*  ATP-Evoked Sustained Vasoconstrictions Mediated by Heteromeric P2X1/4 Receptors in Cerebral Arteries | Stroke
P2 receptors in cardiovascular regulation and disease. Purinergic Signal. 2008;4:1-20. ... Vascular smooth muscle cells from small human omental arteries express P2X1 and P2X4 receptor subunits. Purinergic Signal. In ... Ca2+ entry following P2X receptor activation induces IP3 receptor-mediated Ca2+ release in myocytes from small renal arteries. ... A novel receptor-operated Ca2+-permeable channel activated by ATP in smooth muscle. Nature. 1987;328:275-278. ...
http://stroke.ahajournals.org/content/45/8/2444
*  COA of Suramin sodium salt | Certificate of Analysis | AbMole BioScience
... and non-selectively antagonizes P2 purinergic receptors (10-100 μM).. ... salt is a polysulfonated naphthylurea that inhibits the binding of calmodulin to recognition sites on the ryanodine receptor-1 ...
http://www.abmole.com/literature/suramin-sodium-salt-coa.html
*  Modulation of P2X3 and P2X2/3 Receptors by Monoclonal Antibodies - Sophion
Purinergic homomeric P2X3 and heteromeric P2X2/3 receptors are ligand-gated cation channels activated by ATP. Both receptors ... Modulation of P2X3 and P2X2/3 Receptors by Monoclonal Antibodies. Journal: The Journal of Biological Chemistry Go to journal ... Hence these receptors are considered important therapeutic targets for pain management and development of selective antagonists ... exposure to approximately 20 hours resulted in a profound inhibition of both homomeric hP2X3 and heteromeric hP2X2/3 receptors ...
http://sophion.com/publications/modulation-p2x3-p2x23-receptors-monoclonal-antibodies/
*  Purinergic Receptors | Springer for Research & Development
Knowledge of the distribution of purinergic receptor sites on the plasma membrane of visceral musculature has grown ... investigate the purinergic nerve hypothesis have generated much information concerning the nature of the purinergic receptors ... It is now known that purinergic receptors mediating responses to adenosine and the adenine nucleotides (AMP, ADP and ATP) are ... Adenosine triphosphate (ATP) adenosine adenosine diphosphate (ADP) blood vessel muscle nucleotide plasma membrane receptor ...
https://rd.springer.com/book/10.1007/978-94-009-5816-6
*  Purinergic Receptors and Pain | Bentham Science
Purinergic Receptors and Pain. Author(s): Geoffrey Burnstock. Autonomic Neuroscience Centre, Royal Free and University College ... Geoffrey Burnstock, " Purinergic Receptors and Pain", Current Pharmaceutical Design (2009) 15: 1717. https://doi.org/10.2174/ ... There is a brief summary of the early background literature about purinergic signalling and its involvement in pain, of ATP ... Abstract: There is a brief summary of the early background literature about purinergic signalling and its involvement in pain, ...
http://www.eurekaselect.com/node/69232/article
*  Painful Purinergic Receptors | Journal of Pharmacology and Experimental Therapeutics
Thus, ATP acting at multiple purinergic receptors, either directly on neurons (e.g., P2X3, P2X2/3, and P2Y receptors) or ... P2Y Receptors. In comparison to several of the P2X receptors, the contributions of the metabotropic P2Y receptors to normal and ... In contrast, activation of some other P2 receptors, including P2X4 and P2X7 receptors, and some P2Y (e.g., P2Y2) receptors can ... Furthermore, activation of P2Y2 receptors leads to sensitization of polymodal transient receptor potential-1 receptors. ...
http://jpet.aspetjournals.org/content/324/2/409.long
*  Attenuated Purinergic Receptor Function in Patients with Type 2 Diabetes | Diabetes
Attenuated Purinergic Receptor Function in Patients with Type 2 Diabetes. Pia Thaning, Laurids T Bune, Ylva Hellsten, Henriette ... Attenuated Purinergic Receptor Function in Patients with Type 2 Diabetes. Pia Thaning, Laurids T Bune, Ylva Hellsten, Henriette ... Attenuated Purinergic Receptor Function in Patients with Type 2 Diabetes Message Subject (Your Name) has forwarded a page to ... Attenuated Purinergic Receptor Function in Patients with Type 2 Diabetes. Pia Thaning, Laurids T Bune, Ylva Hellsten, Henriette ...
http://diabetes.diabetesjournals.org/content/early/2009/10/01/db09-1068
*  Purinergic receptor - Biology-Online Dictionary | Biology-Online Dictionary
Science: biochemistry) receptors that use purine nucleotides (e.g. ATP) as ligands. ... Retrieved from "https://www.biology-online.org/dictionary/index.php?title=Purinergic_receptor&oldid=72478" ...
https://www.biology-online.org/dictionary/Purinergic_receptor
*  P2RY2 - Purinergic receptor P2Y2 - Ailuropoda melanoleuca (Giant panda) - P2RY2 gene & protein
Purinergic receptor P2Y2Imported. ,p>Information which has been imported from another database using automatic procedures.,/p ... tr,D2H1G0,D2H1G0_AILME Purinergic receptor P2Y2 (Fragment) OS=Ailuropoda melanoleuca OX=9646 GN=P2RY2 PE=3 SV=1 ... G-protein coupled receptorUniRule annotation. ,p>Information which has been generated by the UniProtKB automatic annotation ... Belongs to the G-protein coupled receptor 1 family.UniRule annotation. Automatic assertion according to rulesi ...
https://www.uniprot.org/uniprot/D2H1G0
*  Age-related changes in P2-purinergic receptors on vascular smooth muscle and endothelium. | Hypertension
Age-related changes in P2-purinergic receptors on vascular smooth muscle and endothelium.. T Koga, Y Takata, K Kobayashi, K ... This suggests that the vascular smooth muscle of young rats has a P2-purinergic receptor leading to relaxation and that this ... The alterations with age of P2-purinergic receptor in the vascular smooth muscle and endothelial cell are not affected by ... In contrast, a P2-purinergic receptor leading to the generation of endothelium-derived relaxing factor may be activated in ...
http://hyper.ahajournals.org/content/19/3/286
*  Methods of screening modulators of mammalian P2X7 purinergic receptors - Patent # 6509163 - PatentGenius
... receptor. The invention further relates to a nucleic acid encoding the P2X.sub.7 receptor and to a method of producing P2X.sub. ... to a purinergic receptor and, particular, to a P2X.sub.7 (also designated P2Z) ... The present invention relates to a P2X.sub.7 receptor, preferably, a mammalian P2X.sub.7 receptor. The present receptor ... to a purinergic receptor and, in particular, to a P2X.sub.7 (also designated P2Z) receptor. The invention further relates to a ...
http://www.patentgenius.com/patent/6509163.html
*  Anti-purinergic receptor P2X 3 Antibody Products from Atlas Antibodies | Biocompare.com
Compare Anti-purinergic receptor P2X 3 Antibody Products from Atlas Antibodies from leading suppliers on Biocompare. View ... Your search returned 1 purinergic receptor P2X 3 Antibodies across 1 supplier. ... Anti-purinergic receptor P2X 3 Antibody Products from Atlas Antibodies. Anti-purinergic receptor P2X 3 Antibody Products from ...
https://www.biocompare.com/pfu/110447/soids/2266575/Antibodies/purinergic_receptor_P2X_3?vids=102592
*  Purinergic receptor P2RY12-dependent microglial closure of the injured blood-brain barrier. | Sigma-Aldrich
Purinergic receptor P2RY12-dependent microglial closure of the injured blood-brain barrier.. [Nanhong Lou, Takahiro Takano, ... We show here that following blood-brain barrier (BBB) breakdown, P2RY12 (purinergic receptor P2Y, G-protein coupled, 12)- ... Because clopidogrel antagonizes the platelet P2Y12 receptor, it is widely prescribed for patients with coronary artery and ...
https://www.sigmaaldrich.com/catalog/papers/26755608
*  Purinergic receptor - Wikipedia
There are three known distinct classes of purinergic receptors, known as P1, P2X, and P2Y receptors. P2X receptors are ligand- ... IUPHAR GPCR Database - Adenosine receptors IUPHAR GPCR Database - P2Y receptors Purinergic Receptors at the US National Library ... The term purinergic receptor was originally introduced to illustrate specific classes of membrane receptors that mediate ... King BF, Burnstock G (2002) Purinergic receptors. In: Pangalos M, Davies C (eds) Understanding G protein-coupled receptors and ...
https://en.wikipedia.org/wiki/Purinergic_receptor
*  Expression of functional P2X7 purinergic receptors in the retinal microvasculature. | IOVS | ARVO Journals
Expression of functional P2X7 purinergic receptors in the retinal microvasculature. You will receive an email whenever this ... H Kawamura, T Sugiyama, DM Wu, DG Puro; Expression of functional P2X7 purinergic receptors in the retinal microvasculature. . ... These effects were mimicked by the P2X7 agonist, Bz-ATP, and prevented by oxidized ATP, a blocker of P2X7 receptors. As with ... Because P2X7 receptors can form membrane pores that are permeable to molecules of , 900 MW, we assessed the uptake of the ...
https://iovs.arvojournals.org/article.aspx?articleid=2420942
*  Time-of-day-dependent expression of purinergic receptors in mouse suprachiasmatic nucleus
Purinergic (P) receptors play a role in cell-cell communication mediated by adenosine (P1 receptors) or ATP (P2 receptors; ... In the brain, purinergic receptors are located on astrocytes and neurons (Kanjhan et al. 1999; Vulchanova et al. 1996). In the ... Time-of-day-dependent expression of purinergic receptors in mouse suprachiasmatic nucleus. Julian Lommen,#1 Anna Stahr,#1 Marc ... During the early light phase, all of these purinergic receptors gave low to moderate Ir. This is consistent with the low Ir of ...
http://pubmedcentralcanada.ca/pmcc/articles/PMC5579179/
*  Antibody Panel to Purinergic Receptors - Product Review 06 | acris-antibodies.com
These receptors are collectively known as nucleotide receptors or "purinergic" receptors. For example these receptors play a ... Home » Reviews » Antibody Panel to Purinergic Receptors - Product Review 06 Antibody Panel to Purinergic Receptors - Product ... Purinergic receptors are a family of ubiquitous transmembrane receptors comprising of two main classes: those stimulated by ... Antibody Tools for Detection of Purinergic Receptors. OriGene Technologies offers a wide range of antibodies to purinergic ...
https://www.acris-antibodies.com/reviews/antibody-panel-purinergic-receptors.htm