Platelet-derived growth factor receptor - Wikipedia
"Structures of a platelet-derived growth factor/propeptide complex and a platelet-derived growth factor/receptor complex". ... Platelet-derived growth factor receptors (PDGF-R) are cell surface tyrosine kinase receptors for members of the platelet- ... Platelet-Derived+Growth+Factor+Receptors at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Portal: ... Heldin CH, Westermark B (April 1989). "Platelet-derived growth factor: three isoforms and two receptor types". Trends in ...
JCI - Human neuroblastoma cells express alpha and beta platelet-derived growth factor receptors coupling with neurotrophic and...
Human neuroblastoma cells express alpha and beta platelet-derived growth factor receptors coupling with neurotrophic and ... Human neuroblastoma cells express alpha and beta platelet-derived growth factor receptors coupling with neurotrophic and ... Both platelet-derived growth factor (PDGF) A- and B-chains are expressed in mammalian neurons, but their precise roles still ... The expression of alpha and/or beta PDGF receptors was detected in a wide variety of neural crest-derived human tumor cell ...
Molecular cloning and functional characterization of the human platelet-derived growth factor alpha receptor gene promoter
Expression of the platelet-derived growth factor alpha receptor (PDGF alpha R) is strictly regulated during mammalian ... Expression of the platelet-derived growth factor alpha receptor (PDGF alpha R) is strictly regulated during mammalian ... Molecular cloning and functional characterization of the human platelet-derived growth factor alpha receptor gene promoter ... This effect is mediated through specific transcription factor binding within the -52/+118 region of the PDGF alpha R gene. ...
Human PDGFRL (Platelet Derived Growth Factor Receptor Like Protein) ELISA Kit | G-EC-02321 | Gentaur Elisa Kits
Platelet Derived Growth Factor Receptor Like Protein) ELISA Kit from Gentaur Elisa Kits. Cat Number: G-EC-02321. USA, UK & ... Human PDGFRL (Platelet Derived Growth Factor Receptor Like Protein) ELISA Kit , G-EC-02321. Gentaur Elisa ... Human PDGFRL (Platelet Derived Growth Factor Receptor Like Protein) ELISA Kit , G-EC-02321 ... Human PDGFRL (Platelet Derived Growth Factor Receptor Like Protein) ELISA Kit , G-EC-02321 , Gentaur Elisa Kits ...
Angiotensin Receptor Blockers and Statins Could Alleviate Atrial Fibrosis via Regulating Platelet-Derived Growth Factor/Rac1 ...
Expression of platelet-derived growth factor (PDGF), Rac1 and nuclear factor-kappa B NF-κB in left atrial of rats. (A-C) ... Expression of platelet-derived growth factor (PDGF), Rac1 and nuclear factor-kappa B NF-κB in human RAAs. (A-C) Expression of ... Angiotensin Receptor Blockers and Statins Could Alleviate Atrial Fibrosis via Regulating Platelet-Derived Growth Factor/Rac1 / ... Angiotensin Receptor Blockers and Statins Could Alleviate Atrial Fibrosis via Regulating Platelet-Derived Growth Factor/Rac1 / ...
Platelet-derived Growth Factor and Its Receptors in Human Glioma Tissue: Expression of Messenger RNA and Protein Suggests the...
The expression of platelet-derived growth factor (PDGF) and its receptors was analyzed in 14 gliomas of various degrees of ... Platelet-derived Growth Factor and Its Receptors in Human Glioma Tissue: Expression of Messenger RNA and Protein Suggests the ... Platelet-derived Growth Factor and Its Receptors in Human Glioma Tissue: Expression of Messenger RNA and Protein Suggests the ... Furthermore, high levels of the PDGF-β receptor (PDGFR-β) and PDGF B-chain mRNA as well as the β receptor protein were found in ...
Cell migration activated by platelet-derived growth factor receptor is blocked by an inverse agonist of the sphingosine 1...
We have previously identified a novel complex between the platelet-derived growth factor (PDGF)β receptor and the sphingosine 1 ... Cell migration activated by platelet-derived growth factor receptor is blocked by an inverse agonist of the sphingosine 1- ... activated by platelet-derived growth factor receptor is blocked by an inverse agonist of the sphingosine 1-phosphate receptor-1 ... These findings are the first to report that a GPCR inverse-agonist reduces growth factor-induced receptor tyrosine kinase ...
Rat PDGFRb(Platelet Derived Growth Factor Receptor Beta) ELISA Kit - iBiomagazine
Rat PDGFRb(Platelet Derived Growth Factor Receptor Beta) ELISA Kit. Human Platelet Derived Growth Factor Receptor Beta (PDGFRB ... Human Platelet Derived Growth Factor Receptor Beta (PDGFRb) ELISA Kit. RDR-PDGFRb-Hu-48Tests Reddot Biotech 48 Tests. 577.2 EUR ... Human Platelet Derived Growth Factor Receptor Beta (PDGFRb) ELISA Kit. SEC061Hu-1x48wellstestplate Cloud-Clone 1x48-wells test ... Human Platelet Derived Growth Factor Receptor Beta (PDGFRb) ELISA Kit. SEC061Hu-1x96wellstestplate Cloud-Clone 1x96-wells test ...
Peptide Derivatives of Platelet-Derived Growth Factor Receptor Alpha Inhibit Cell-Associated Spread of Human Cytomegalovirus -...
Peptide Derivatives of Platelet-Derived Growth Factor Receptor Alpha Inhibit Cell-Associated Spread of Human Cytomegalovirus. , ... Platelet-derived development issue receptor-α (PDGFRα)-positive interstitial cells (ICs) are extensively distributed in varied ... Plays a role in platelet activation, secretion of agonists from platelet granules, and in thrombin-induced platelet aggregation ... Podoplanin binds to C-type lectin-like receptor 2 (CLEC-2) which is solely expressed by platelets and quite a lot of immune ...
Biosensor-based Binding Assay for Platelet-Derived Growth Factor Receptor-α Autoantibodies in Human Serum
... M. Cuccioloni;G. ... Herein, we report a novel assay designed to detect anti-platelet-derived growth factor receptor α (PDGFRα) autoantibodies in ... Herein, we report a novel assay designed to detect anti-platelet-derived growth factor receptor α (PDGFRα) autoantibodies in ... This receptor-based biosensor, based on the reversible interaction between a blocked macromolecule and soluble ligands, and ...
Receptor, Platelet-Derived Growth Factor beta | Profiles RNS
Platelet-Derived Growth Factor beta*Receptor, Platelet-Derived Growth Factor beta. *Receptor, Platelet Derived Growth Factor ... Receptors, Platelet-Derived Growth Factor [D08.811.913.696.620.682.725.400.900]. *Receptor, Platelet-Derived Growth Factor beta ... Receptors, Platelet-Derived Growth Factor [D12.776.543.750.060.625]. *Receptor, Platelet-Derived Growth Factor beta [D12.776. ... Receptors, Platelet-Derived Growth Factor [D12.776.543.750.750.400.630]. *Receptor, Platelet-Derived Growth Factor beta [ ...
Recombinant Platelet Derived Growth Factor Receptor Alpha (PDGFRa) - danabio
B-type receptor for platelet-derived growth factor mediates a chemotactic response by means of ligand-induced activation of the...
Structure of the receptor for platelet-derived growth factor helps define a family of closely related growth factor receptors ... B-type receptor for platelet-derived growth factor mediates a chemotactic response by means of ligand-induced activation of the ... B-type receptor for platelet-derived growth factor mediates a chemotactic response by means of ligand-induced activation of the ... Cloning and expression of a cDNA coding for the human platelet-derived growth factor receptor: evidence for more than one ...
Platelet Disorders: Overview of Platelet Disorders, Pathophysiology of Platelet Disorders, Autoimmune Thrombocytopenias
... coagulation factors, and the endothelial cells lining the blood vessels. The platelets arise from the fragmentation of the ... purinergic receptor; PAR = protease-activated receptor; PDGF = platelet-derived growth factor; PF4 = platelet factor 4; PIP2 = ... purinergic receptor; PAR = protease-activated receptor; PDGF = platelet-derived growth factor; PF4 = platelet factor 4; PIP2 = ... and growth factors (eg, platelet-derived growth factor and transforming growth factors). The dense granules contain ...
Platelet-derived growth factor selectively inhibits NR2B-containing N-methyl-D-aspartate receptors in CA1 hippocampal neurons.
... ... Platelet-derived growth factor (PDGF) beta receptor activation inhibits N-methyl-d-aspartate (NMDA)-evoked currents in ... by preferentially targeting NR2B receptors, provides an important mechanism for neuroprotection by growth factors in the ... After neuronal injury, PDGFbeta receptors and PDGF-BB are up-regulated and PDGFbeta receptor activation is neuroprotective ...
Platelet Disorders: Overview of Platelet Disorders, Pathophysiology of Platelet Disorders, Autoimmune Thrombocytopenias
... coagulation factors, and the endothelial cells lining the blood vessels. The platelets arise from the fragmentation of the ... purinergic receptor; PAR = protease-activated receptor; PDGF = platelet-derived growth factor; PF4 = platelet factor 4; PIP2 = ... purinergic receptor; PAR = protease-activated receptor; PDGF = platelet-derived growth factor; PF4 = platelet factor 4; PIP2 = ... and growth factors (eg, platelet-derived growth factor and transforming growth factors). The dense granules contain ...
Blood-Brain Barrier Breakdown: Early Dementia Biomarker: platelet-derived growth factor receptor-β (PDGFRβ)
Platelet-derived growth factor receptor tyrosine phosphorylation requires protein geranylgeranylation but not farnesylation<...
McGuire, T. F., Qian, Y., Vogt, A., Hamilton, A. D., & Sebti, S. M. (1996). Platelet-derived growth factor receptor tyrosine ... Platelet-derived growth factor receptor tyrosine phosphorylation requires protein geranylgeranylation but not farnesylation. ... Platelet-derived growth factor receptor tyrosine phosphorylation requires protein geranylgeranylation but not farnesylation. / ... McGuire, TF, Qian, Y, Vogt, A, Hamilton, AD & Sebti, SM 1996, Platelet-derived growth factor receptor tyrosine phosphorylation ...
Recent developments in the structure, function and regulation of platelet-derived growth factor and its receptors<...
keywords = "platelet-derived growth factor, post-transcriptional control, receptor down regulation, receptors, transcriptional ... Recent developments in the structure, function and regulation of platelet-derived growth factor and its receptors. In: ... Recent developments in the structure, function and regulation of platelet-derived growth factor and its receptors. / Tiesman, ... Recent developments in the structure, function and regulation of platelet-derived growth factor and its receptors. ...
MedlinePlus: Genes: P
PDGFRA: platelet derived growth factor receptor alpha. *PDGFRB: platelet derived growth factor receptor beta ... PDGFB: platelet derived growth factor subunit B. * ... POGZ: pogo transposable element derived with ZNF domain. *POLG ... PKD1: polycystin 1, transient receptor potential channel interacting. *PKD2: polycystin 2, transient receptor potential cation ...
Platelet-derived growth factor alpha and beta receptors have overlapping functional activities towards fibroblasts |...
As there is redundancy in signalling between the five PDGF ligand isoforms and three PDGF receptor isoforms, and deletion of ... Neutralising antibodies against PDGFRs were shown to block signalling through PDGFRα and PDGFRβ receptors, reduce human PDGF-AA ... either of the receptors in vivo produces an embryonic lethal phenotype, it is not know which ligand and receptor combinations ... In this study, we used PDGFR-specific neutralising antibodies to dissect out receptor-specific signalling events in fibroblasts ...
Table 2 - Nosocomial Co-Transmission of Avian Influenza A(H7N9) and A(H1N1)pdm09 Viruses between 2 Patients with Hematologic...
B-cell antigen receptor-induced apoptosis requires both Ig alpha and Ig beta
The response of a B cell to antigen is dependent on the surface expression of a clonotypic B-cell receptor complex (BCR) ... Platelet-Derived Growth Factor alpha * Receptor, Platelet-Derived Growth Factor beta * Receptors, Platelet-Derived Growth ... Receptor, Platelet-Derived Growth Factor alpha * Receptor, Platelet-Derived Growth Factor beta ... Receptors, Platelet-Derived Growth Factor / genetics * Receptors, Platelet-Derived Growth Factor / immunology ...
PLATELET-DERIVED
This assay is designed to evaluate the presence of one of the main factors that contributes to the resistance of a cell ... in particular if there is platelets aggregation as this will protect transformed cells from destruction. It will also ... containing the factor to be destroyed (apoptosis). High PDGF Rβ quantities are associated with an inhibition of the destruction ... Platelet-derived Growth Factor (pdgf) Gene Expression. *Platelet-derived Growth Factor Receptor. Beta (pdgf Rβ) Gene Expression ...
"Platelet derived growth factor receptor β (PDGFRβ) is a host receptor " by Ryan W J Steel, Vladimir Vigdorovich et al.
Here, we identified the human platelet-derived growth factor receptor β (hPDGFRβ) as one such protein receptor. Deletion ... and its extracellular portion contains adhesive domains that are predicted to engage host receptors. ... constructs showed that the von Willebrand factor type A and thrombospondin repeat domains of TRAP are both required for optimal ... Platelet derived growth factor receptor β (PDGFRβ) is a host receptor for the human malaria parasite adhesin TRAP.. ...
VEGFD vascular endothelial growth factor D [Homo sapiens (human)] - Gene - NCBI
enables platelet-derived growth factor receptor binding TAS Traceable Author Statement. more info ... The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/ ... vascular endothelial growth factor D. Names. c-fos induced growth factor (vascular endothelial growth factor D). ... VEGFD vascular endothelial growth factor D [Homo sapiens] VEGFD vascular endothelial growth factor D [Homo sapiens]. Gene ID: ...
Abstract | Acute Myeloid Leukemia with Platelet-Derived Growth Factor Receptor β (PDGFRβ) Rearrangement Successfully Treated...
Acute Myeloid Leukemia with Platelet-Derived Growth Factor Receptor β (PDGFRβ) Rearrangement Successfully Treated with ... Rearrangements in the platelet-derived growth factor receptor β (PDGFRβ) gene result in greater constitutive enzymatic activity ... Acute Myeloid Leukemia with Platelet-Derived Growth Factor Receptor β (PDGFRβ) Rearrangement Successfully Treated with ... Impact Factor* 4.7. Submit Manuscript. Grant Support Articles. * Was this a Bilateral Testicular Torsion? Dilemma of a ...
Stromal platelet-derived growth factor receptor α (PDGFRα) provides a therapeutic target independent of tumor cell PDGFRα...
T1 - Stromal platelet-derived growth factor receptor α (PDGFRα) provides a therapeutic target independent of tumor cell PDGFRα ... In lung cancer, platelet-derived growth factor receptor α (PDGFRα) is expressed frequently by tumor-associated stromal cells ... Stromal platelet-derived growth factor receptor α (PDGFRα) provides a therapeutic target independent of tumor cell PDGFRα ... Stromal platelet-derived growth factor receptor α (PDGFRα) provides a therapeutic target independent of tumor cell PDGFRα ...
RCSB PDB - 6JOK: Crystal structure of PDGFRA in complex with sunitinib by soaking
Platelet-derived growth factor receptor alpha. A. 356. Homo sapiens. Mutation(s): 0 Gene Names: PDGFRA, PDGFR2, RHEPDGFRA. EC: ...