LAMININ RECEPTOR 1. *laminin receptor 1, human. *LAMININ RECEPTOR, 67-KD. *Laminin Receptor-1 ...
Belkin AM, Stepp MA (2000). "Integrins as receptors for laminins". Microsc. Res. Tech. 51 (3): 280-301. doi:10.1002/1097-0029( ... Laminin subunit alpha-2 is a protein that in humans is encoded by the LAMA2 gene. Laminin, an extracellular matrix protein, is ... This gene encodes the alpha 2 chain, which constitutes one of the subunits of laminin 2 (merosin) and laminin 4 (s-merosin). ... 2000). "A novel laminin alpha2 isoform in severe laminin alpha2 deficient congenital muscular dystrophy". Neurology. 55 (8): ...
laminin receptor homolog. tumor suppressor QM. NP_001243506.2. *EC 3.6.5.3. NP_001243509.2. *EC 3.6.5.3 ...
View mouse Lamc2 Chr1:152998502-153062193 with: phenotypes, sequences, polymorphisms, proteins, references, function, expression
J:29907 Miner JH, et al., Molecular cloning of a novel laminin chain, alpha 5, and widespread expression in adult mouse tissues ...
We recently showed that the polymodal receptor transient receptor potential vanilloid 4 (TRPV4), a member of the transient ... Louis, MO) and laminin (5 μg/ml; Invitrogen Life Technologies) and were incubated at 37°C in 96.5% air/3.5% CO2. ... Transient Receptor Potential Vanilloid 4 Is Essential in Chemotherapy-Induced Neuropathic Pain in the Rat. Nicole Alessandri- ... Liedtke W, Choe Y, Marti-Renom MA, Bell AM, Denis CS, Sali A, Hudspeth AJ, Friedman JM, Heller S (2000) Vanilloid receptor- ...
Interferon alpha/beta receptor 1 (7). * Laminin 2 alpha (8). * Laminin alpha 4/LAMA4 (7). ...
Dystroglycan is a highly glycosylated extracellular matrix receptor with essential functions in skeletal muscle and the nervous ... The atomic details of matrix binding were revealed by a high-resolution crystal structure of laminin-G-like (LG) domains 4 and ... A structural study defines a unique binding mode between the LARGE-generated oligosaccharide and the matrix protein laminin. ... an extracellular matrix receptor essential for muscle function. ... 5 (LG4 and LG5) of laminin-α2 bound to a LARGE-synthesized ...
Menard S, Castronovo V, Tagliabue E and Sobel ME: New insights into the metastasis-associated 67 kD laminin receptor. J Cell ... Fukai Y, Masuda N, Kato H, et al: Correlation between laminin-5 gamma2 chain and epidermal growth factor receptor expression in ... Laminin 5 (Ln5, also known as laminin 332) is an extracellular matrix (ECM) protein that plays an important role in cell ... Miyazaki K: Laminin-5 (laminin-332): unique biological activity and role in tumor growth and invasion. Cancer Sci. 97:91-98. ...
Scavenger receptors. 8578 (SCARF1). Domain-containing proteins not elsewhere classified [BR:hsa04990]. Laminin domain- ...
PspC also has adhesion properties through interactions with sIgA and the laminin receptor [25]. ... Recognition of pneumolysin by Toll-like receptor 4 confers resistance to pneumococcal infection. Proc. Natl. Acad. Sci. USA ...
... as well as vitronectin and laminin (4). However, AGE engagement of cellular receptors would provide a biologic amplification ... Multiligand receptors * Is the class A macrophage scavenger receptor (SR-A) multifunctional? - The mouses tale Nick Platt et ... Scavenger receptor class B type I is a multiligand HDL receptor that influences diverse physiologic systems Monty Krieger ... Krieger, M, Herz, J. Structures and functions of multiligand lipoprotein receptors: macrophage scavenger receptors and LDL ...
Host cell receptors consisting of laminin, lectin, and SAG1 are involved in T gondii tachyzoite attachment and penetration. ...
Integrin alpha 6 beta 1 is a receptor for laminin. Integrin alpha 6 beta 4 is also a receptor for laminin and is a structural ...
Enteric species F human adenoviruses use laminin-binding integrins as co-receptors for infection of Ht-29 cells ... Adenovirus receptors: implications for tropism, treatment and targeting Reviews in Medical Virology, John Wiley & Sons 2009, ... Adenovirus receptors: implications for targeting of viral vectors TIPS - Trends in Pharmacological Sciences, Elsevier 2012, Vol ... Polysialic acid is a cellular receptor for human adenovirus 52 Proceedings of the National Academy of Sciences of the United ...
... and certain integrins as the cellular receptors. The type F adenoviruses use laminin-binding-integrins, in contrast to the RGD- ... Type F adenoviruses and the EKC-causing adenoviruses are substantially different in their cellular receptor homing, and thus ... Most adenoviruses including Type F adenoviruses use Coxsackie-Adenovirus Receptor (CAR) ...
37 kDa laminin receptor precursor Short name: 37LRP 37/67 kDa laminin receptor Short name: LRP/LR 67 kDa laminin receptor Short ... 67LR Colon carcinoma laminin-binding protein Laminin receptor 1 Short name: LamR Laminin-binding protein precursor p40 Short ... Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the ... Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the ...
This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 ... Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, ... that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides ...
Endothelial cell protein C receptor: a multiliganded and multifunctional receptor. Blood. 2014;124:1553-62.PubMedGoogle Scholar ... and disrupt endothelial connections to the extracellular matrix by displacing laminin (40-42). Immune-mediated targeting of ... Cao W, Henry MD, Borrow P, Yamada H, Elder JH, Ravkov EV, et al. Identification of alpha-dystroglycan as a receptor for ... Molecular analysis of the interaction of LCMV with its cellular receptor [alpha]-dystroglycan. J Cell Biol. 2001;155:301-10. ...
... express laminin receptors and adhere to and spread on laminin in vitro. A specific amino acid sequence in the A chain of ... D) Localisation of laminin in the normal colon. Laminin is found in the basal lamina of blood vessels in the submucosa (top of ... Laminin is a heterotrimer consisting of α, β, and γ chains.17 The colocalisation of mast cells with laminin was shown with ... C) Distribution of laminin and mast cells in the submucosa in the same fibrotic stricture. Laminin is mainly located in the ...
Identification of alpha-actinin 4 and 67 kDa laminin receptor as stage-specific markers in esophageal cancer via proteomic ... B): ADC binds to the pro-survival receptor of cancer cells, inhibiting its function, commencing apoptosis. (C): ADC binds to ... B): ADC binds to the pro-survival receptor of cancer cells, inhibiting its function, commencing apoptosis. (C): ADC binds to ... This Ab-drug conjugate also blocks the cells pro-survival receptor besides forming a cytotoxic load coupled by a selective ...
Signaling by Receptor Tyrosine Kinases (Homo sapiens) * Signaling by MET (Homo sapiens) * MET promotes cell motility (Homo ... Laminins bind HSPG2 (Homo sapiens) * Laminins with alpha-1, -2 or -5 [extracellular region] (Homo sapiens) * Laminin-213 [ ... Laminins bind Nidogens 1, 2 (Homo sapiens) * Laminins with gamma-1, gamma-3 [extracellular region] (Homo sapiens) * Laminin-213 ... Laminin interactions (Homo sapiens) * Formation of laminin networks (Homo sapiens) * Laminin network [extracellular region] ( ...
Loss of basement membrane, receptor and cytoskeletal lattices in a laminin-deficient muscular dystrophy. Yurchenco, P.D., Cheng ... Estradiol stimulates tyrosine phosphorylation of the insulin-like growth factor-1 receptor and insulin receptor substrate-1 in ... autoimmunity to basement membrane antigens is regulated in C57BL/6 and MRL/MpJ mice transgenic for anti-laminin Ig receptors. ... Basement membrane and the SIKVAV laminin-derived peptide promote tumor growth and metastases. Sweeney, T.M., Kibbey, M.C., Zain ...
Whereas α2 laminins promoted islet cell clustering, they did not affect gene expression. In contrast, culturing on Laminin-421 ... Compared to ECs, pancreatic pericytes produce significantly higher levels of α2 and α4 laminin chains, which constitute the ... We further found that the pericytic laminin isoforms differentially regulate mouse β-cells. ... Laminins are heterotrimers composed of α, β, and γ chains, when the α chain largely dictates receptor specificity16. Three ...
Nucleotide and Nucleoside Receptors. Signalosome. Integrins (includes tetraspanins). Netrins and Laminins. Fibronectin Family. ... Additional Immunoglobulin-related Receptors (includes NK cell receptors). Butyrophilin Family. Interleukins and Their Receptors ... Toll-like Receptors. Pyrin and Associated Functions. Complement. Fc Receptors. MS4 Family. Superoxide Pathway. HLA and Related ... Receptor Tyrosine Kinases. Non-Receptor Tyrosine Kinase Pathways. Protein Tyrosine Phosphatases. MAP Kinase Pathways. ...
37-kDa laminin receptor precursor modulates cytotoxic necrotizing factor 1-mediated RhoA activation and bacterial uptake. The ... AMPA Receptor Surface Expression Is Regulated by S-Nitrosylation of Thorase and Transnitrosylation of NSF. Cell Reports. 33: ... Mechanistic basis for receptor-mediated pathological α-synuclein fibril cell-to-cell transmission in Parkinsons disease. ... Reduction of functional N-methyl-D-aspartate receptors in neurons by RNase P-mediated cleavage of the NR1 mRNA. Journal of ...
Dystroglycan also functions as dual receptor for agrin and laminin-2 in the Schwann cell membrane. The muscle and nonmuscle ... virus receptor activity dystroglycan binding actin binding calcium ion binding protein binding structural constituent of muscle ... Dystroglycan is a laminin binding component of the dystrophin-glycoprotein complex which provides a linkage between the ... Wnt-driven LARGE2 mediates laminin-adhesive O-glycosylation in human colonic epithelial cells and colorectal cancer. ...
Increased laminin expression precedes lymphocytic infiltration. Journal of Autoimmunity, 10, 59-65. doi:10.1006/jaut.1996.0109 ... T Cell Receptor; T Cell Receptor Variable Domain; Adverse Drug Reactions; Autoimmune Diseases ... 2004) T cell receptors recognizing type II collagen in HLA-DR-transgenic mice characterized by highly restricted V beta usage. ... Watkins, S. and Pichler, W. (2013) T cell receptor variable β20-1 harbors a nucleotide binding pocket in the CDR2β loop. Open ...
Integrins as receptors for laminins. Microsc. Res. Tech.. 51. :. 280. -301.. Crossref ... Adenosine A(2A) receptor stimulation reduces inflammation and neointimal growth in a murine carotid ligation model. ... Adenosine A(2A) receptor stimulation reduces inflammation and neointimal growth in a murine carotid ligation model. ... The collagen receptor integrins have distinct ligand recognition and signaling functions. Matrix Biol. ...