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*  Platelet-derived growth factor receptor alpha (pdgfr-α) gene in zebrafish embryonic development | ScholarBank@NUS
Liu, L., Chong, S.-W., Balasubramaniyan, N.V., Korzh, V., Ge, R. (2002). Platelet-derived growth factor receptor alpha (pdgfr-α ... Platelet-derived growth factor receptor alpha (pdgfr-α) gene in zebrafish embryonic development. ...
http://scholarbank.nus.edu.sg/handle/10635/101418
*  Different functions of the platelet-derived growth factor-alpha and -beta receptors for the migration and proliferation of...
Different functions of the platelet-derived growth factor-alpha and -beta receptors for the migration and proliferation of ... Different functions of the platelet-derived growth factor-alpha and -beta receptors for the migration and proliferation of ... Different functions of the platelet-derived growth factor-alpha and -beta receptors for the migration and proliferation of ... Different functions of the platelet-derived growth factor-alpha and -beta receptors for the migration and proliferation of ...
http://circres.ahajournals.org/content/75/4/682
*  KEGG BRITE: KEGG Orthology (KO) - Equus caballus (horse)
100059815 PDGFRA; platelet derived growth factor receptor alpha 100071665 PDGFRB; platelet derived growth factor receptor beta ... platelet-derived growth factor receptor alpha [EC:2.7.10.1] K05089 PDGFRB; platelet-derived growth factor receptor beta [EC:2.7 ... platelet-derived growth factor subunit B K05450 PDGFC_D; platelet derived growth factor C/D K05450 PDGFC_D; platelet derived ... platelet derived growth factor subunit B 100062015 PDGFC; platelet derived growth factor C 100061488 PDGFD; platelet derived ...
http://www.genome.jp/kegg-bin/get_htext?ecb00001+100054723
*  Platelet-derived growth factors | Article about platelet-derived growth factors by The Free Dictionary
In minor injuries, small oval bodies called... Explanation of platelet-derived growth factors ... Find out information about platelet-derived growth factors. see blood clotting blood clotting, process by which the blood ... Platelet-Derived Growth Factor Receptor Alpha. *Platelet-Derived Growth Factor Receptor Alpha ... platelet-derived growth factors such as platelet-derived growth factor and transforming growth factor-[beta]1, and lipid pools ...
https://encyclopedia2.thefreedictionary.com/platelet-derived+growth+factors
*  Abstract 250: Elucidating the Role of Platelet Derived Growth Factor Receptor Alpha Signaling in Cardiac Fibroblasts |...
Abstract 250: Elucidating the Role of Platelet Derived Growth Factor Receptor Alpha Signaling in Cardiac Fibroblasts. Malina J ... Abstract 250: Elucidating the Role of Platelet Derived Growth Factor Receptor Alpha Signaling in Cardiac Fibroblasts ... Abstract 250: Elucidating the Role of Platelet Derived Growth Factor Receptor Alpha Signaling in Cardiac Fibroblasts ... Abstract 250: Elucidating the Role of Platelet Derived Growth Factor Receptor Alpha Signaling in Cardiac Fibroblasts ...
http://circres.ahajournals.org/content/117/Suppl_1/A250
*  Outcome of patients with Platelet Derived Growth Factor Receptor Alpha-mutated GIST in the tyrosine kinase inhibitor era |...
Outcome of patients with Platelet Derived Growth Factor Receptor Alpha-mutated GIST in the tyrosine kinase inhibitor era. ... Outcome of patients with Platelet Derived Growth Factor Receptor Alpha-mutated GIST in the tyrosine kinase inhibitor era ... Outcome of patients with Platelet Derived Growth Factor Receptor Alpha-mutated GIST in the tyrosine kinase inhibitor era ... Outcome of patients with Platelet Derived Growth Factor Receptor Alpha-mutated GIST in the tyrosine kinase inhibitor era ...
http://clincancerres.aacrjournals.org/content/early/2012/06/20/1078-0432.CCR-11-3025
*  TARGETING THE ALPHA RECEPTOR FOR PLATELET-DERIVED-GROWTH FACTOR AS A PRIMARY OR COMBINATION THERAPY IN A PRECLINICAL MODEL OF...
TARGETING THE ALPHA RECEPTOR FOR PLATELET-DERIVED-GROWTH FACTOR AS A PRIMARY OR COMBINATION THERAPY IN A PRECLINICAL MODEL OF ... TARGETING THE ALPHA RECEPTOR FOR PLATELET-DERIVED-GROWTH FACTOR AS A PRIMARY OR COMBINATION THERAPY IN A PRECLINICAL MODEL OF ... TARGETING THE ALPHA RECEPTOR FOR PLATELET-DERIVED-GROWTH FACTOR AS A PRIMARY OR COMBINATION THERAPY IN A PRECLINICAL MODEL OF ... TARGETING THE ALPHA RECEPTOR FOR PLATELET-DERIVED-GROWTH FACTOR AS A PRIMARY OR COMBINATION THERAPY IN A PRECLINICAL MODEL OF ...
http://clincancerres.aacrjournals.org/content/early/2010/09/02/1078-0432.CCR-10-1863
*  Aberrant platelet-derived growth factor alpha-receptor transcript as a diagnostic marker for early human germ cell tumors of...
These data show that the 1.5-kb platelet-derived growth factor alpha-receptor transcript can be used as a highly selective ... show alternative splicing and alternative promoter use of the platelet-derived growth factor alpha-receptor gene, giving rise ... up a reverse transcriptase-polymerase chain reaction strategy for characterization of the various transcripts for this receptor ... Aberrant platelet-derived growth factor alpha-receptor transcript as a diagnostic marker for early human germ cell tumors of ...
https://www.semanticscholar.org/paper/Aberrant-platelet-derived-growth-factor-transcript-Mosselman-Looijenga/e0156903d9306cf5f356029dd4612f6d9c9a7fa5
*  Platelet-derived growth factor receptor, alpha polypeptide | definition of platelet-derived growth factor receptor, alpha...
What is platelet-derived growth factor receptor, alpha polypeptide? Meaning of platelet-derived growth factor receptor, alpha ... alpha polypeptide in the Medical Dictionary? platelet-derived growth factor receptor, alpha polypeptide explanation free. ... What does platelet-derived growth factor receptor, alpha polypeptide mean? ... Looking for online definition of platelet-derived growth factor receptor, ...
https://medical-dictionary.thefreedictionary.com/platelet-derived+growth+factor+receptor%2C+alpha+polypeptide
*  Neomycin is a platelet-derived growth factor (PDGF) antagonist that allows discrimination of PDGF alpha- and beta-receptor...
Neomycin is a platelet-derived growth factor (PDGF) antagonist that allows discrimination of PDGF alpha- and beta-receptor ... Receptors; Cell Surface/drug effects/genetics/*physiology, Receptors; Platelet-Derived Growth Factor, Recombinant Proteins/ ... Platelet-Derived Growth Factor/antagonists & inhibitors/metabolism/*pharmacology, ...
http://uu.diva-portal.org/smash/record.jsf?pid=diva2:101174
*  NAVER Academic | Pediatric KIT wild-type and platelet-derived growth factor receptor alpha-wild-type gastrointestinal stromal...
Pediatric KIT wild-type and platelet-derived growth factor receptor alpha-wild-type gastrointestinal stromal tumors share KIT ... Receptor, Platelet-Derived Growth Factor alpha, Signal Transduction. ...
http://academic.naver.com/article.naver?doc_id=146516689
*  PDGFRA gene - Genetics Home Reference
platelet derived growth factor receptor alpha. Enable Javascript to view the expand/collapse boxes.. Printable PDF Open All ... OMIM: PLATELET-DERIVED GROWTH FACTOR RECEPTOR, ALPHA. *. Roufosse FE, Goldman M, Cogan E. Hypereosinophilic syndromes. Orphanet ... The PDGFRA gene provides instructions for making a protein called platelet-derived growth factor receptor alpha (PDGFRA), which ... platelet-derived growth factor receptor alpha. *platelet-derived growth factor receptor, alpha polypeptide ...
https://ghr.nlm.nih.gov/gene/PDGFRA
*  Compound Report Card
Platelet-derived growth factor receptor alpha Homo sapiens 0.909 CHEMBL203 Epidermal growth factor receptor erbB1 Homo sapiens ... Tyrosine-protein kinase receptor RET Homo sapiens 0.986 CHEMBL2007 Platelet-derived growth factor receptor alpha Homo sapiens ... Tyrosine-protein kinase receptor RET Homo sapiens 0.999 CHEMBL279 Vascular endothelial growth factor receptor 2 Homo sapiens ... Vascular endothelial growth factor receptor 1 Homo sapiens 0.409 CHEMBL5014 Serine/threonine-protein kinase RIPK2 Homo sapiens ...
https://www.ebi.ac.uk/chembl/compound/inspect/CHEMBL682
*  Compound Report Card
Stem cell growth factor receptor Homo sapiens 1.000 CHEMBL2007 Platelet-derived growth factor receptor alpha Homo sapiens 1.000 ... Platelet-derived growth factor receptor beta DailyMed Stem cell growth factor receptor inhibitor Stem cell growth factor ... Platelet-derived growth factor receptor alpha Homo sapiens 1.000 CHEMBL1974 Tyrosine-protein kinase receptor FLT3 Homo sapiens ... Platelet-derived growth factor receptor beta inhibitor ... Platelet-derived growth factor receptor beta Homo sapiens 0.859 ...
https://www.ebi.ac.uk/chembl/compound/inspect/CHEMBL941
*  Browsing Pathology by Title
Platelet-derived growth factor receptor alpha signaling pathways in development and liver disease  Hayes, Brian Joseph (2014- ... Platelet derived growth factor receptor alpha (PDGFRα) signaling is critical for development and disease. Insufficient PDGFRα ... Liver fibrosis is mediated by hepatic stellate cells (HSCs), which respond to a variety of cytokine and growth factors to ... Merkel cell polyomavirus-specific CD8 T cells in Merkel cell carcinoma: T cell receptor diversity & novel immune therapies  ...
https://digital.lib.washington.edu/researchworks/handle/1773/4952/browse?rpp=20&sort_by=1&type=title&etal=-1&starts_with=K&order=ASC
*  Regulation of male sex determination: genital ridge formation and Sry activation in mice | SpringerLink
Platelet-derived growth factor receptor alpha. Pod1/Tcf21/bHLHa23/capsulin/epicardin. Podocyte-expressed 1/transcription factor ... Leydig cell loss and spermatogenic arrest in platelet-derived growth factor (PDGF)-A-deficient mice. J Cell Biol 149:1019-1026 ... Kim Y, Bingham N, Sekido R, Parker KL, Lovell-Badge R et al (2007) Fibroblast growth factor receptor 2 regulates proliferation ... Platelet-derived growth factor subunit A. Pdgfra. ... Fibroblast growth factor receptor 2. ESCs. Embryonic stem cells ...
https://link.springer.com/article/10.1007%2Fs00018-014-1703-3
*  Amplification of the platelet-derived growth factor receptor-A (PDGFRA) gene occurs in oligodendrogliomas with grade IV...
Receptor, Platelet-Derived Growth Factor alpha/genetics*. Substance. *Receptor, Platelet-Derived Growth Factor alpha ... Amplification of the platelet-derived growth factor receptor-A (PDGFRA) gene occurs in oligodendrogliomas with grade IV ... Activation of the platelet-derived growth factor (PDGF) signaling system has been implicated in the development and malignant ... Overexpression of PDGF system components, particularly the alpha subtype receptor (PDGFRA), is common in glial tumors, and ...
https://www.ncbi.nlm.nih.gov/pubmed/10850862?dopt=Abstract
*  Eisai and Merck Announce China National Medical Products Administration (NMPA) Approval of LENVIMA® (lenvatinib) for Treatment...
... including fibroblast growth factor (FGF). receptors FGFR1-4; the platelet derived growth factor receptor alpha. (PDGFRα), KIT, ... inhibits the kinase activities of vascular endothelial growth factor. (VEGF) receptors VEGFR1 (FLT1), VEGFR2 (KDR), and VEGFR3 ... perforation, risk factors such as prior surgery or radiotherapy were. present. Permanently discontinue in patients who develop ... Additional factors that could cause results. to differ materially from those described in the forward-looking. statements can ...
https://www.benzinga.com/pressreleases/18/09/b12304898/eisai-and-merck-announce-china-national-medical-products-administratio
*  Patent US5268358 - PDGF receptor blocking peptides - Google Patents
... and can serve as immunogens to raise receptor-specific antibodies. ... as well as the chronic process of atherogenesis utilizing oligopeptides corresponding to regions of the PDGF receptor protein. ... Antibodies for the alpha platelet-derived growth factor receptor. US6663881 *. 18 Dec 2001. 16 Dec 2003. Neorx Corporation. ... proliferation by interfering with the binding of platelet-derived growth factor to the platelet-derived growth factor receptor. ...
http://www.google.ca/patents/US5268358
*  Protein (Weighted) Links for PubMed (Select 22933705) - Protein - NCBI
PREDICTED: platelet-derived growth factor receptor alpha isoform X6 [Homo sapiens]. 807 aa protein ... platelet-derived growth factor receptor alpha isoform 1 precursor [Homo sapiens]. 1089 aa protein ... platelet-derived growth factor receptor alpha isoform 2 precursor [Homo sapiens]. 807 aa protein ... platelet-derived growth factor receptor alpha isoform 4 [Homo sapiens]. 1102 aa protein ...
https://www.ncbi.nlm.nih.gov/protein?LinkName=pubmed_protein_weighted&from_uid=22933705
*  Federal Register :: Prospective Grant of Exclusive License: Development of Antibody-Based Therapeutics That...
... and methods that incorporate or are derived from the molecule known as alpha platelet derived growth factor receptor (α-PDGFR ... "Type Alpha Platelet Derived Growth Factor Receptor Gene", published as WO 90/10013 (9/7/1990) to ImClone Systems Incorporated ... Development of Antibody-Based Therapeutics That Specifically Bind the Platelet-Derived Growth Factor Receptor Alpha (CD140A/ ... and methods of utilizing antibody-based products that specifically bind the alpha platelet-derived growth factor receptor (α- ...
https://www.federalregister.gov/documents/2004/08/26/04-19538/prospective-grant-of-exclusive-license-development-of-antibody-based-therapeutics-that-specifically
*  PDGFRA Recombinant Human Protein (without Catalytic Activity Domain), His Tag, Invitrogen™ Sino Biological™ | Fisher Scientific
... alpha polypeptide (PDGFRA), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in protein ... Platelet-derived growth factor receptor, alpha polypeptide (PDGFRA), recombinant human protein is supplied as a lyophilized ... Receptor Tyrosine Kinases,Growth Factor Receptors. Gene Alias. PDGFRA, CD140a, mgC74795, PDGFR2, Rhe-PDGFRA. ... Platelet-derived growth factor receptor, alpha. Validated Application. Assay Standard. Expression System. Mammalian. ...
https://www.fishersci.ca/shop/products/sino-biological-pdgfra-recombinant-human-protein-without-catalytic-activity-domain-his-tag/10556h08h50
*  Olaratumab - DrugBank
... of olaratumab in combination with doxorubicin resulted in significant reduction of cancer cell proliferation and tumor growth. ... is a fully human IgG1 monoclonal antibody with antitumor activity that selectively binds the external domain of human platelet- ... derived growth factor receptor (PDGFR)-α with high affinity and blocks ligand binding. It is composed of two heavy chain ... the Akt pathway in metastatic prostate cells through transactivation of the alpha-platelet-derived growth factor receptor. ...
https://www.drugbank.ca/drugs/DB06043
*  1 Million Study on Leiomyosarcoma Set to Begin
Platelet-derived growth factor receptor alpha (PDGFRA): Acts upstream of the PI3K-AKT-mTOR pathway. Recently, therapies ... We will continue to study methods for targeting this hormone receptor, as a means to constrain the growth of LMS. Such ... Coordinate expression of colony-stimulating factor-1 and colony-stimulating factor-1-related proteins is associated with poor ... Many factors regulate the cell cycle, so that cells do not continuously divide, or proliferate. The PI3K-AKT-mTOR pathway ...
http://sarcomahelp.org/leiomyosarcoma-collaborative-research.html
*  Gene Info
MF] platelet-derived growth factor alpha-receptor activity *[MF] platelet-derived growth factor binding *[MF] platelet-derived ... BP] platelet-derived growth factor receptor signaling pathway *[BP] platelet-derived growth factor receptor-alpha signaling ... BP] positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway *[BP ... MF] vascular endothelial growth factor binding *[MF] vascular endothelial growth factor-activated receptor activity BioCarta ...
https://cgap.nci.nih.gov/Genes/GeneInfo?ORG=Hs&CID=74615