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*  Toxins | Free Full-Text | Immunotoxin Therapies for the Treatment of Epidermal Growth Factor Receptor-Dependent Cancers
Recombinant immunotoxins are therapeutic molecules consisting of an antibody or receptor ligand joined to a protein cytotoxin, ... combining the specific targeting of a cancer-expressed receptor with the potent cell killing of cytotoxic enzymes. Over the ... Many epithelial cancers rely on enhanced expression of the epidermal growth factor receptor (EGFR) to drive proliferation and ... Many epithelial cancers rely on enhanced expression of the epidermal growth factor receptor (EGFR) to drive proliferation and ...
http://www.mdpi.com/2072-6651/8/5/137
*  Novel and existing mutations in the tyrosine kinase domain of the epidermal growth factor receptor are predictors of optimal...
epidermal growth factor receptor. The process of cell division, growth, differentiation and death is a highly regulated process ... Several class of trans membrane receptors play a pivot role in this process, of these, epidermal growth factor receptor (EGFR) ... Novel and existing mutations in the tyrosine kinase domain of the epidermal growth factor receptor are predictors of optimal ... In this study, we investigate the predictive value of epidermal growth factor receptor (EGFR) mutations in achieving optimal ...
http://www.mesothelioma-line.com/2008/11/11/novel-and-existing-mutations-in-the-tyrosine-kinase-domain-of-the-epidermal-growth-factor-receptor-are-predictors-of-optimal-resectability-in-malignant-peritoneal-mesothelioma/
*  Mechanisms of Acquired Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors and New Therapeutic...
Title: Mechanisms of Acquired Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors and New Therapeutic ... Mechanisms of Acquired Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors and New Therapeutic ... Uncontrolled activation of MET, another tyrosine kinase receptor, has been implicated in neoplastic invasive growth. MET is ... Uncontrolled activation of MET, another tyrosine kinase receptor, has been implicated in neoplastic invasive growth. MET is ...
http://www.eurekaselect.com/73933/article
*  Presence of epidermal growth factor receptor as an indicator of poor prognosis in patients with breast cancer. | Journal of...
... suggesting that epidermal growth factor receptor state could be a useful prognostic marker. Epidermal growth factor receptor ... and there is an inverse relation to oestrogen receptor state. We assessed the presence of epidermal growth factor receptors as ... Presence of epidermal growth factor receptor as an indicator of poor prognosis in patients with breast cancer. ... Presence of epidermal growth factor receptor as an indicator of poor prognosis in patients with breast cancer. ...
http://jcp.bmj.com/content/38/11/1225
*  Insulin-like growth factor (IGF)-I obliterates the pregnancy-associated protection against mammary carcinogenesis in rats:...
... the notion that tumor growth promotion seen in IGF-I-treated parous rats is caused by activation of estrogen receptor-α via the ... which may affect the activity of the growth hormone/insulin-like growth factor (IGF)-I axis. We investigated the effects of IGF ... Expressions of cyclin D1 and transforming growth factor-β3 in the mammary gland were lower in the age-matched virgin rats than ... The protein levels of estrogen receptor-α in the mammary gland was significantly higher in the age-matched virgin animals than ...
https://breast-cancer-research.biomedcentral.com/articles/10.1186/bcr812
*  Direct visualization of the phosphorylated epidermal growth factor receptor during its internalization in A-431 cells. | JCB
Epidermal growth factor (EGF) rapidly stimulates receptor autophosphorylation in A-431 cells. After 1 min the phosphorylated ... Direct visualization of the phosphorylated epidermal growth factor receptor during its internalization in A-431 cells.. J L ... Direct visualization of the phosphorylated epidermal growth factor receptor during its internalization in A-431 cells. ... With further incubation at 37 degrees C, approximately 50% of the phosphorylated EGF receptor was internalized (t1/2 = 5 min) ...
http://jcb.rupress.org/content/105/6/2751
*  Clinical Utility of Serum Human Epidermal Growth Factor Receptor Type 2 Testing as a Marker of Therapeutic Response In Tissue...
Human Epidermal growth factor Receptor type 2 (HER2) is over expressed in 20.0-30.0% of breast cancers and is currently ... Human epidermal growth factor receptor type 2, Serum marker, Therapeutic response Abbreviations. HER2: Human Epidermal Growth ... Human Epidermal growth factor Receptor type 2 (HER2) is over expressed in 20.0-30.0% of breast cancers and is currently ... Human Epidermal growth factor Receptor type 2 (HER2) is a glycoprotein of 185 kDa that comprises an Extracellular ligand- ...
https://www.clinmedjournals.org/articles/ijccr/international-journal-of-cancer-and-clinical-research-ijccr-4-089.php?jid=ijccr
*  Lysophosphatidylcholine Increases Expression of Heparin-Binding Epidermal Growth Factor-Like Growth Factor in Human T...
... like domain of human heparin-binding EGF-like growth factor/diphtheria toxin receptor and inhibits specifically its mitogenic ... Tumor necrosis factor increases transcription of the heparin-binding epidermal growth factor-like growth factor gene in ... Platelet-activating factor stimulates transcription of the heparin-binding epidermal growth factor-like growth factor in ... expression of platelet-derived growth factor A-chain and heparin-binding epidermal growth factor-like growth factor in human ...
http://circres.ahajournals.org/content/80/5/638
*  Activation of the Human Epidermal Growth Factor Receptor | SpringerLink
Polypeptide growth factors have been recognized as important determinants In the regulation of cellular proliferation and ... Epidermal Growth Factor Receptor Human Epidermal Growth Factor Receptor Epidermal Growth Factor Receptor Kinase Protein ... Epidermal growth factor induces rapid, reversible aggregation of the purified epidermal growth factor receptor. Biochemistry 26 ... C-kinase phosphorylates the epidermal growth factor receptor and reduces its epidermal growth factor-stimulated protein-kinase ...
https://link.springer.com/chapter/10.1007/978-3-642-73142-6_14
*  Epidermal Growth Factor Receptor | Springer for Research & Development
ERBB; ERBB1; Erb-B2 receptor tyrosine kinase 1; Erythroblastic leukemia viral (V-Erb-B) oncogene homolog (Avian); HER1; Proto- ... oncogene C-ErbB-1; Receptor tyrosine-protein kinase ErbB-1 The... ... Heparin-binding epidermal growth factor-like growth factor (HB- ... The epidermal growth factor receptor (EGFR, also known as ErbB1) is the first of four members of the ErbB lineage of receptor ... A mutation in the epidermal growth factor receptor in waved-2 mice has a profound effect on receptor biochemistry that results ...
https://rd.springer.com/referenceworkentry/10.1007/978-3-319-67199-4_101589
*  Cancers | Free Full-Text | Epidermal Growth Factor Receptor in Pancreatic Cancer
Epidermal growth factor receptor (EGFR) is a transmembrane glycoprotein, which is expressed in normal human tissues. It is a ... member of the tyrosine kinase family of growth factors receptors and is encoded by proto-oncogenes. Several studies have ... Epidermal Growth Factor Receptor in Pancreatic Cancer. Melissa Oliveira-Cunha 1,* , William G. Newman 2. ... Epidermal growth factor receptor (EGFR) is a transmembrane glycoprotein, which is expressed in normal human tissues. It is a ...
http://www.mdpi.com/2072-6694/3/2/1513
*  Copy of Epidermal Growth Factor Receptor (EGFR) by Brendan Vonick on Prezi
Copy of Epidermal Growth Factor Receptor (EGFR). No description by Brendan Vonick. on 4 December 2012 ...
https://prezi.com/mjqqoxvfkmfe/copy-of-epidermal-growth-factor-receptor-egfr/
*  Dissertations.se: EPIDERMAL GROWTH FACTOR RECEPTOR
... about EPIDERMAL GROWTH FACTOR RECEPTOR. Search and download thousands of Swedish university dissertations. Full text. Free. ... prognostic factor; growth control; VEGF; vascular endothelial growth factor; EGFR; epidermal growth factor receptor; pEGFR; ... epidermal growth factor receptor'. Showing result 1 - 5 of 109 swedish dissertations containing the words epidermal growth ... epidermal growth factor receptor; tyrosine kinase; kinase activity; Abstract : Cytokine receptor activation is dependent on ...
http://www.dissertations.se/about/epidermal+growth+factor+receptor/
*  Why Do Cancer Cells Become "Addicted" to Oncogenic Epidermal Growth Factor Receptor?
The author discusses three new studies in PLoS Medicine that shed light on the mechanisms involved in apoptosis triggered by EGFR kinase inhibitors.
https://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.0040321
*  Photochemical internalization of epidermal growth factor receptor-targeted drugs
The present thesis concerns epidermal growth factor receptor (EGFR) targeting toxins delivered by photochemical internalization ... the most sensitive target of disulfonated tetraphenylporphyrin-based photodynamic therapy on epidermal growth factor receptor. ... Photochemical internalization of epidermal growth factor receptor-targeted drugs. Weyergang, Anette Doctoral thesis ...
https://www.duo.uio.no/handle/10852/12267
*  Molecular cloning and expression of an additional epidermal growth factor receptor-related gene | PNAS
Effective Inhibition of the Epidermal Growth Factor/Epidermal Growth Factor Receptor Binding by Anti-Epidermal Growth Factor ... Epidermal growth factor (EGF), transforming growth factor alpha (TGF-alpha), and amphiregulin are structurally and functionally ... Molecular cloning and expression of an additional epidermal growth factor receptor-related gene. G D Plowman, G S Whitney, M G ... Role of extracellular subdomains of p185c-neu and the epidermal growth factor receptor in ligand-independent association and ...
https://www.pnas.org/content/87/13/4905?ijkey=63b1b4392d7fe54c3159968b054d1953d8b0a6c6&keytype2=tf_ipsecsha
*  EPS15 (epidermal growth factor receptor pathway substrate 15)
... epidermal growth factor receptor pathway substrate 15), Authors: Olivier Bernard. Published in: Atlas Genet Cytogenet Oncol ... EPS15 (epidermal growth factor receptor pathway substrate 15). Written. 1998-04. Olivier Bernard. ... early endosome membrane endocytic recycling cargo receptor activity negative regulation of epidermal growth factor receptor ... early endosome membrane endocytic recycling cargo receptor activity negative regulation of epidermal growth factor receptor ...
http://atlasgeneticsoncology.org/Genes/AF1pID11.html
*  Epidermal Growth Factor Receptor Protein: A Biological Marker for Oral Precancer and Cancer
Epidermal growth factor receptor (EGFR), a tyrosine kinase receptor of the ErbB family, and the biological receptor of EGF and ... J. R. Grandis and D. J. Tweardy, "Elevated levels of transforming growth factor α and epidermal growth factor receptor ... "Asynchronous modulation of transforming growth factor α and epidermal growth factor receptor protein expression in progression ... Epidermal Growth Factor Receptor Protein: A Biological Marker for Oral Precancer and Cancer. Ashish Mahendra,1 Balasundari ...
https://www.hindawi.com/journals/jds/2014/158709/
*  Epidermal growth factor receptors in the oesophagus. | Gut
The quantity and distribution of epidermal growth factor receptors (EGF-R) in oesophageal mucosa was studied in the oesophagus ...
http://gut.bmj.com/content/33/4/439
*  c-Met, epidermal growth factor receptor, and insulin-like gr... : Melanoma Research
c-Met, epidermal growth factor receptor, and insulin-like growth factor-1 receptor are important for growth in uveal melanoma ... c-Met, epidermal growth factor receptor, and insulin-like growth factor-1 receptor are important for growth in uveal melanoma ... c-Met, epidermal growth factor receptor, insulin-like growth factor-1R, tumor migration, uveal melanoma. ... UM cell lines were evaluated for c-Met, epidermal growth factor receptor (EGFR), and insulin-like growth factor-1R (IGF-1R) ...
http://journals.lww.com/melanomaresearch/Abstract/2012/04000/c_Met,_epidermal_growth_factor_receptor,_and.3.aspx
*  epidermal growth factor receptor ELISA Kits from antibodies-online | Biocompare.com
Compare epidermal growth factor receptor ELISA Kits from antibodies-online from leading suppliers on Biocompare. View ... Epidermal Growth Factor Receptor (P-EGFR) ELISA Kit antibodies-online *Detection Target: Epidermal Growth Factor Receptor (P- ... Epidermal Growth Factor Receptor (P-EGFR) ELISA Kit antibodies-online *Detection Target: Epidermal Growth Factor Receptor (P- ... Epidermal Growth Factor Receptor (P-EGFR) ELISA Kit antibodies-online *Detection Target: Epidermal Growth Factor Receptor (P- ...
https://www.biocompare.com/pfu/110627/soids/2-318519/Assay_Kit/ELISA_epidermal_growth_factor_receptor?vids=104431
*  Dissertations.se: PHOSPHORYLATED EPIDERMAL GROWTH FACTOR RECEPTOR
... about PHOSPHORYLATED EPIDERMAL GROWTH FACTOR RECEPTOR. Search and download thousands of Swedish university dissertations. Full ... prognostic factor; growth control; VEGF; vascular endothelial growth factor; EGFR; epidermal growth factor receptor; pEGFR; ... epidermal growth factor receptor; tyrosine kinase; kinase activity; Abstract : Cytokine receptor activation is dependent on ... Abstract : Human epidermal growth factor receptor 2 (HER2) overexpressing breast cancers (HER2+ breast cancer) are associated ...
http://www.dissertations.se/about/phosphorylated+epidermal+growth+factor+receptor/
*  Browsing by Subject "epidermal growth factor receptor"
Browsing by Subject "epidermal growth factor receptor". 0-9. A. B. C. D. E. F. G. H. I. J. K. L. M. N. O. P. Q. R. S. T. U. V. ... Cell growth, differentiation, and proliferation are all carefully regulated processes. Disruptions in these processes are often ...
https://repositories.lib.utexas.edu/browse?type=subject&value=epidermal%20growth%20factor%20receptor
*  Three generations of epidermal growth factor receptor tyrosine kinase | DDDT
Sensitizing mutations in epidermal growth factor receptor (EGFR) gene (EGFRm+), such as exon 19 deletions and exon 21 L858R ... Keywords: lung cancer, epidermal growth factor receptor, tyrosine kinase inhibitors, T790M mutation ... Three generations of epidermal growth factor receptor tyrosine kinase inhibitors developed to revolutionize the therapy of lung ... Sensitizing mutations in epidermal growth factor receptor (EGFR) gene (EGFRm+), such as exon 19 deletions and exon 21 L858R ...
https://www.dovepress.com/three-generations-of-epidermal-growth-factor-receptor-tyrosine-kinase--peer-reviewed-article-DDDT
*  RCSB PDB - Protein Feature View - Epidermal growth factor receptor substrate 15 - P42566 (EPS15 HUMAN)
Involved in the internalization of ligand-inducible receptors of the receptor tyrosine kinase (RTK) type, in particular EGFR. ... Involved in cell growth regulation. May be involved in the regulation of mitogenic signals and control of cell proliferation. ... Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent ...
https://www.rcsb.org/pdb/protein/P42566