Structure of the EphB6 receptor ectodomain. | NECAT
Home » Structure of the EphB6 receptor ectodomain.. Structure of the EphB6 receptor ectodomain.. Publication Type:. Journal ... where clustering of ligand-bound receptors relies on two distinct receptor/receptor interfaces. Interestingly, most unliganded ... p,Eph receptors are the largest group amongst the receptor tyrosine kinases and are divided into two subgroups, A and B, based ... To further our understanding of Eph receptor function, we crystallized the EphB6-ECD and determined its three-dimensional ...
EPHB6 - Wikipedia
Ephrin type-B receptor 6 is a protein that in humans is encoded by the EPHB6 gene. Ephrin receptors and their ligands, the ... "Entrez Gene: EPHB6 EPH receptor B6". Flanagan JG, Vanderhaeghen P (1998). "The ephrins and Eph receptors in neural development ... Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The ephrin receptor encoded by this ... 2000). "Ephrin-B2 is a candidate ligand for the Eph receptor, EphB6". FEBS Lett. 466 (1): 169-74. doi:10.1016/S0014-5793(99) ...
Integration of cancer-related genetic landscape of Eph receptors and ephrins with proteomics identifies a crosstalk between...
EPHB6. This identifies a crosstalk between EPHB6 and EGFR, and further experiments confirm the ability of EPHB6 to modulate ... Eph receptors and their ephrin ligands are viewed as promising targets for cancer treatment; however, targeting them is ... of cancer-related genetic landscape of Eph receptors and ephrins with proteomics identifies a crosstalk between EPHB6 and EGFR ... Taken together, our observations show EPHB6 involvement in EGFR action, suggesting its targeting might be beneficial in EGFR- ...
Prof Isabelle Lucet, Division Head | WEHI Researcher Profile
The intracellular domains of the EphB6 and EphA10 receptor tyrosine pseudokinases function as dynamic signalling hubs. Biochem ... Eph receptor signalling: from catalytic to non-catalytic functions. Oncogene. 2019 Sep;38(39):6567-6584. doi: 10.1038/s41388- ... Receptor tyrosine pseudokinases have emerged as critical players in developmental processes. Deregulation of this class of ... Improving cancer therapeutic design through structural biology of ephrin receptors * Student Research ...
GSE24574 BCL6 HIGH VS LOW TFH CD4 TCELL UP
NIF3L1 and EPHB6 Interaction - Wiki-Pi
Image Series List :: Spinal CordMolecular genetic evaluation of Cichorium endivia L. as an anticancer agent against colorectal cancer | International...
Human Genome Epidemiology Literature Finder|Home|PHGKB
Target Information | Therapeutic Target Database
Targeting the KLF5-EphA2 axis can restrain cancer stemness and overcome chemoresistance in basal-like breast cancer
A paradigm shift in EPH receptor interaction: biological relevance of EPHB6 interaction with EPHA2 and EPHB2 in breast ... Ephrin type-A receptor 2 (EphA2) is a member of the tyrosine receptor kinases, a family of membrane proteins recognized as ... Ephrin type-A receptor 2 (EphA2), a member of the receptor tyrosine kinase (RTK) family, is a type I transmembrane glycoprotein ... In addition, the multiple signaling patterns of the EphA2 receptor complicate targeting strategies, and the most appropriate ...
Recombinant Mouse EphA7 Protein (His Tag) | Beta LifeScience
EPHB6. The Eph family of receptor tyrosine kinases (comprising EphA and EphB receptors) has been implicated in synapse ... Interleukins and Receptors Growth Factors and Receptors Chemokines and Receptors Tumor Necrosis Factors and Receptors (TNFs) ... Ephrin type-A receptor 7, also known as EphA7, belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family ... Colony-Stimulating Factors and Receptors (CSFs) Interferons and Receptors (IFN) Other Cytokines ...
Semi-Quantitative Arrays
VIP Receptor 2, Visfatin, Vitamin D Receptor, Vitamin D-BP, Vitamin K-dependent protein S, Vitronectin, VWF, WIF-1, Wilms Tumor ... EphB6, Ephrin-B1, Ephrin-B2, EPHX2, Epiregulin, EPPK1, Eps15, ERAB, ErbB2, ErbB3, ErbB4, ERp29, ERp57, ERp72, ERRa, ... VIP Receptor 2, Visfatin, Vitamin D-BP, Vitamin D Receptor, Vitamin K-dependent protein S, Vitronectin, VNN1, VSIG4, VWF, WDR1 ... Endothelin Receptor A, Enolase 2, ENPP2, EN-RAGE, Eotaxin / CCL11, Eotaxin-2 / MPIF-2, Eotaxin-3 / CCL26, EpCAM, EphA1, EphA2, ...
MH DELETED MN ADDED MN
D12.776.543.750.630.500.781 Receptor, EphB5 D12.776.543.750.60.500.875 D12.776.543.750.630.500.875 Receptor, EphB6 D12.776. ... Receptor Aggregation G4.299.780 G4.774 Receptor Cross-Talk G4.299.785 G4.794 Receptor Protein-Tyrosine Kinases D12.776.543.750. ... 60 D12.776.543.750.630 Receptor Tyrosine Kinase-like Orphan Receptors D12.776.543.750.60.233 D12.776.543.750.630.233 Receptor, ... Receptor Activator of Nuclear Factor-kappa B D23.50.301.264.35.594 D23.101.100.110.594 Receptor Activity-Modifying Protein 1 ...
MH DELETED MN ADDED MN
D12.776.543.750.630.500.781 Receptor, EphB5 D12.776.543.750.60.500.875 D12.776.543.750.630.500.875 Receptor, EphB6 D12.776. ... Receptor Aggregation G4.299.780 G4.774 Receptor Cross-Talk G4.299.785 G4.794 Receptor Protein-Tyrosine Kinases D12.776.543.750. ... 60 D12.776.543.750.630 Receptor Tyrosine Kinase-like Orphan Receptors D12.776.543.750.60.233 D12.776.543.750.630.233 Receptor, ... Receptor Activator of Nuclear Factor-kappa B D23.50.301.264.35.594 D23.101.100.110.594 Receptor Activity-Modifying Protein 1 ...
MH DELETED MN ADDED MN
D12.776.543.750.630.500.781 Receptor, EphB5 D12.776.543.750.60.500.875 D12.776.543.750.630.500.875 Receptor, EphB6 D12.776. ... Receptor Aggregation G4.299.780 G4.774 Receptor Cross-Talk G4.299.785 G4.794 Receptor Protein-Tyrosine Kinases D12.776.543.750. ... 60 D12.776.543.750.630 Receptor Tyrosine Kinase-like Orphan Receptors D12.776.543.750.60.233 D12.776.543.750.630.233 Receptor, ... Receptor Activator of Nuclear Factor-kappa B D23.50.301.264.35.594 D23.101.100.110.594 Receptor Activity-Modifying Protein 1 ...
MH DELETED MN ADDED MN
D12.776.543.750.630.500.781 Receptor, EphB5 D12.776.543.750.60.500.875 D12.776.543.750.630.500.875 Receptor, EphB6 D12.776. ... Receptor Aggregation G4.299.780 G4.774 Receptor Cross-Talk G4.299.785 G4.794 Receptor Protein-Tyrosine Kinases D12.776.543.750. ... 60 D12.776.543.750.630 Receptor Tyrosine Kinase-like Orphan Receptors D12.776.543.750.60.233 D12.776.543.750.630.233 Receptor, ... Receptor Activator of Nuclear Factor-kappa B D23.50.301.264.35.594 D23.101.100.110.594 Receptor Activity-Modifying Protein 1 ...
MH DELETED MN ADDED MN
D12.776.543.750.630.500.781 Receptor, EphB5 D12.776.543.750.60.500.875 D12.776.543.750.630.500.875 Receptor, EphB6 D12.776. ... Receptor Aggregation G4.299.780 G4.774 Receptor Cross-Talk G4.299.785 G4.794 Receptor Protein-Tyrosine Kinases D12.776.543.750. ... 60 D12.776.543.750.630 Receptor Tyrosine Kinase-like Orphan Receptors D12.776.543.750.60.233 D12.776.543.750.630.233 Receptor, ... Receptor Activator of Nuclear Factor-kappa B D23.50.301.264.35.594 D23.101.100.110.594 Receptor Activity-Modifying Protein 1 ...
PUJANA BRCA2 PCC NETWORK
Alana L. Welm | School of Medicine
Cunha S, Lin YC, Goossen EA, DeVette CI, Albertella MR, Thomson S, Mulvihill MJ, Welm AL (2014). The RON receptor tyrosine ... EPHB6 augments both development and drug sensitivity of triple-negative breast cancer tumours. Oncogene, 37(30), 4073-4093. ... Arnesen S, Polaski JT, Blanchard Z, Osborne KS, Welm AL, OConnell RM, Gertz J (2023). Estrogen receptor alpha mutations ... hormone receptor positive metastatic breast cancer. Breast Cancer Res (23(1), p. 100). England. ...
ETV2 promotes osteogenic differentiation of human dental pulp stem cells through the ERK/MAPK and PI3K-Akt signaling pathways |...
Also, increased VEGF/VEGF receptor expression has been reported to be related to the PI3K-Akt and ERK/MAPK signaling pathways [ ... EphB6, and FBXO32). As shown in Fig. 4d, the results of qRT-PCR revealed that those genes displayed similar expression trends ... "regulation of signaling receptor activity." In particular, the term "positive regulation of ERK1 and ERK2 cascade" indicated ...
June | 2017 | immune-source.com
immune Uncategorized is a repressor of glucocorticoid receptor transcription.., R547, Rabbit polyclonal to GRF-1.GRF-1 the ... immune Uncategorized Rabbit Polyclonal to EPHB6., Tozadenant Intestinal fibrosis, caused by an extreme deposition of ... A non-IgE-dependent receptor Even, FMLP-R, which will not appear to make use of syk for signaling16, induces humble lack of ... As a result, within an atopic individual with 250,000 receptors, just 2500 are occupied with an antigen-specific IgE as well as ...
HER2/neu
receptor tyrosine kinase. Cellular component. • integral component of membrane. • membrane. • myelin. • receptor complex. • ... It is also frequently called HER2 (from human epidermal growth factor receptor 2) or HER2/neu.[5][6][7] ... "Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene". Science. 230 ( ... "ERBB2 erb-b2 receptor tyrosine kinase 2 [Homo sapiens (human)] - Gene - NCBI". www.ncbi.nlm.nih.gov. Retrieved 2016-06-14.. ...
Antibody
ELISA Kit
Mouse EphB2 Biotinylated Antibody BAF467: R&D Systems
There are two classes of receptors, designated A and B. Both the A and B class receptors have an extracellular region ... In Western blots, approximately 5% cross-reactivity with recombinant mouse (rm) EphB6, recombinant rat EphB1, and rmEphB3 is ... Soluble monomeric ligands bind the receptor but do not induce receptor autophosphorylation and activation (2). In vivo, the ... EphB2, also known as Cek5, Nuk, Erk, Qek2, Tyro5, Sek3, Hek5, and Drt (1), is a member of the Eph receptor family which binds ...
ThermoPA132946VEGF （BIOTIN）赛默飞-上海易汇生物科技有限公
Thermo OPA115292 PROKINETICIN RECEPTOR 2 EA ￥6,713.00 EA. Thermo OPA115394 PIERCE ANTI-ENDOTHELIN A RECEPTOR RABBIT POLYCLONAL ... Thermo PA129783 EPHB6 EA ￥6,713.00 EA. Thermo PA129786 TRPC6 EA ￥6,713.00 EA ... Thermo OPA115619 PIERCE ANTI-GASTRIN-RELEASI NG PEPTIDE RECEPTOR RABBIT ￥6,975.00 NG PEPTIDE RECEPTOR RABBIT ... Thermo PA120630 PIERCE ANTI-SOMATOSTATIN RECEPTOR 2 RABBIT POLYCLONAL ￥6,975.00 RECEPTOR 2 RABBIT POLYCLONAL ...
Volume 7, Issue 21 | Oncotarget
A Toll-like receptor 2 agonist-fused antigen enhanced antitumor immunity by increasing antigen presentation and the CD8 memory ... EphB6 overexpression and Apc mutation together promote colorectal cancer. EphB6 overexpression and Apc mutation together ... A Toll-like receptor 2 agonist-fused antigen enhanced antitumor immunity by increasing antigen presentation and the CD8 memory ... Nuclear receptor 4A1 (NR4A1) as a drug target for treating rhabdomyosarcoma (RMS). ...
Co-stimulatory and Co-inhibitory Molecules Research Areas: R&D Systems
Interactive Pathway: T Cell Co-Signaling Pathway: Ligand-Receptor Interactions * Mini-review: B7 & CD28/CTLA-4 Receptor ... EphB6. *Integrin alpha 4 beta 1. *Integrin alpha 4 beta 7/LPAM-1 ... Nectin and Nectin-like Ligand/Receptor Co-Signaling Molecules. ... receptor superfamily. Molecules in the IgSF are further classified as members of the B7/CD28 family, T cell immunoglobulin and ... and nectin and nectin-like binding receptor family. ...