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*  Pretreatment With Intracoronary Enalaprilat Protects Human Myocardium During Percutaneous Coronary Angioplasty | JACC: Journal...
1997) Angiotensin-converting enzyme inhibitors potentiate preconditioning through bradykinin B2 receptor activation in human ... and ACE inhibitors potentiate ischemic PC in human atrial trabeculae through activation of bradykinin receptors (6). ... 1999) Bradykinin-induced preconditioning in patients undergoing coronary angioplasty. J Am Coll Cardiol 34:639-650. ... Both adenosine and bradykinin (whose bioavailability is enhanced by ACE inhibitors) can trigger PC experimentally (13), ...
http://www.onlinejacc.org/content/49/15/1607
*  JCI - Senescence-associated phenotypes in Akita diabetic mice are enhanced by absence of bradykinin B2 receptors
Thus, absence of the bradykinin B2 receptor increases the oxidative stress, mitochondrial DNA damage, and many senescence- ... Senescence-associated phenotypes in Akita diabetic mice are enhanced by absence of bradykinin B2 receptors. ... Senescence-associated phenotypes in Akita diabetic mice are enhanced by absence of bradykinin B2 receptors. ... or absence of the bradykinin B2 receptor, increase kidney damage in diabetic mice. We demonstrate here that this is part of a ...
https://www.jci.org/articles/view/26958/pdf
*  Excess of Aminopeptidase A in the Brain Elevates Blood Pressure via the Angiotensin II Type 1 and Bradykinin B2 Receptors...
Both bradykinin B1 [20, 21] and B2 receptor were reported to contribute neurogenic hypertension; however, B2 receptor is ... Bradykinin in the cerebrospinal fluid (CSF) [17] and bradykinin B1 and B2 receptors [18] increased in SHR. The pressor response ... Protocol 2 (Icv Administration of APA under AT1 Receptor Blockade, Inhibition of Aminopeptidase Activity, or Bradykinin B2 ... Excess of Aminopeptidase A in the Brain Elevates Blood Pressure via the Angiotensin II Type 1 and Bradykinin B2 Receptors ...
https://www.hindawi.com/journals/ijhy/2017/3967595/
*  Age-dependent renal responses to the bradykinin B2- receptor antagonist icatibant in conscious lambs | Regulatory, Integrative...
Age-dependent renal responses to the bradykinin B2- receptor antagonist icatibant in conscious lambs ... 2000) Renal haemodynamic effects of B2 receptor agonist, bradykinin, and B2 receptor antagonist, HOE 140, in conscious lambs. ... 1996) Renal bradykinin and vasopressin receptors: ligand selectivity and classification. Kidney Int 50:586-592. ... 1997) Ontogeny of bradykinin B2 receptors in the rat kidney: implications for segmental nephron maturation. Kidney Int 51:739- ...
http://ajpregu.physiology.org/content/281/4/R1311
*  Proangiogenic Effect of Angiotensin-Converting Enzyme Inhibition Is Mediated by the Bradykinin B2 Receptor Pathway |...
Proangiogenic Effect of Angiotensin-Converting Enzyme Inhibition Is Mediated by the Bradykinin B2 Receptor Pathway ... Male (8-week-old) knockout mice lacking the bradykinin B2 receptor gene (B2−/−) and wild-type J129Sv/Bl6 controls (Jackson ... Gohlke P, Kuwer I, Schnell A, Amann K, Mall G, Unger T. Blockade of bradykinin B2 receptors prevents the increase in capillary ... Proangiogenic Effect of Angiotensin-Converting Enzyme Inhibition Is Mediated by the Bradykinin B2 Receptor Pathway. Jean- ...
http://circres.ahajournals.org/content/89/8/678
*  Bradykinin B2 Receptor-antagonist Anatibant In Neurotrauma (BRAIN) - AdisInsight
Your email address will be used to create a unique number used exclusively to identify you on AdisInsight. Your email address will not be stored or maintained within AdisInsight. Your unique identifier number will be stored in your browser data on your device. This will allow us to know it's you when you access AdisInsight from your computer, tablet, or phone. To do this you will need to enter your email address the first time to visit AdisInsight from a new device. After that we will recognize you and you will not have to enter your email again unless you have deleted your browser data. We will use your unique identifier number to provide anonymous information to your subscribing organization to allow them to accurately assess the value AdisInsight delivers. For additional information on how we protect your personal information, please refer to our privacy policy . ...
https://adisinsight.springer.com/trials/700020306?error=cookies_not_supported&code=3bb615f6-d33f-4b09-8252-c00502270fc7
*  Bradykinin receptor B2 - Wikipedia
Bradykinin receptor B2 is a G-protein coupled receptor for bradykinin, encoded by the BDKRB2 gene in humans. The B2 receptor is ... "Entrez Gene: BDKRB2 bradykinin receptor B2". "Bradykinin Receptors: B2". IUPHAR Database of Receptors and Ion Channels. ... also potentiates bradykinin action on B2 receptors. Kallidin also signals through the B2 receptor. An antagonist for the ... "Two B1 and B2 bradykinin receptor antagonists fail to inhibit the Ca2+ response elicited by bradykinin in human skin ...
https://en.wikipedia.org/wiki/Bradykinin_receptor_B2
*  AID 277735 - Antagonist potency at human bradykinin B2 receptor assessed as effect on inositol monophosphate accumulation in...
Antagonist potency at human bradykinin B2 receptor assessed as effect on inositol monophosphate accumulation in CHOdhfr- cells. ...
https://pubchem.ncbi.nlm.nih.gov/bioassay/277735
*  Molecular structure and expression of rat bradykinin B2 receptor gene. Evidence for alterative splicing - MDC Repository
Molecular structure and expression of rat bradykinin B2 receptor gene. Evidence for alterative splicing ... Molecular structure and expression of rat bradykinin B2 receptor gene. Evidence for alterative splicing. ... Alternative Splicing, Amino Acid Sequence, Base Sequence, Bradykinin Receptors, DNA Sequence Analysis, Exons, Genetic Promoter ...
http://edoc.mdc-berlin.de/1076/
*  Correction to "Negative and positive regulatory epitopes in the C-terminal domains of the human B1 and B2 bradykinin receptor...
Correction to "Negative and positive regulatory epitopes in the C-terminal domains of the human B1 and B2 bradykinin receptor ... Correction to "Negative and positive regulatory epitopes in the C-terminal domains of the human B1 and B2 bradykinin receptor ... Correction to "Negative and positive regulatory epitopes in the C-terminal domains of the human B1 and B2 bradykinin receptor ... Correction to "Negative and positive regulatory epitopes in the C-terminal domains of the human B1 and B2 bradykinin receptor ...
http://molpharm.aspetjournals.org/content/62/3/762
*  Metabolically stable bradykinin B2 receptor agonists enhance transvascular drug delivery into malignant brain tumors by...
Metabolically stable bradykinin B2 receptor agonists, methionine-lysine-bradykinin and labradimil, enhance the transvascular ... In this study we investigated the systemic actions of labradimil, as well as other bradykinin B2 receptor agonists with a range ... The decrease in systemic blood pressure correlated with the known metabolic stability of the bradykinin B2 receptor agonist ... Metabolically stable bradykinin B2 agonists, methionine-lysine-bradykinin and labradimil, had differential effects on the ...
https://translational-medicine.biomedcentral.com/articles/10.1186/1479-5876-7-33
*  Bradykinin B1 and B2 receptors both have protective roles in renal ischemia/reperfusion injury. - PubMed - NCBI
Bradykinin B1 and B2 receptors both have protective roles in renal ischemia/reperfusion injury.. Kakoki M1, McGarrah RW, Kim HS ... Thus, both the B1 and B2 bradykinin receptors play an important role in reducing DNA damage, apoptosis, morphological and ... Bradykinin B1 and B2 receptors both have protective roles in renal ischemia/reperfusion injury ... Bradykinin B1 and B2 receptors both have protective roles in renal ischemia/reperfusion injury ...
https://www.ncbi.nlm.nih.gov/pubmed/17452647
*  Uneven Evolutionary Rates of Bradykinin B1 and B2 Receptors in Vertebrate Lineages
Bradykinin B1/chemistry/*genetics, Receptor; Bradykinin B2/chemistry/*genetics, Reverse Transcriptase Polymerase Chain Reaction ... The two bradykinin receptor subtypes B1 and B2 are well characterized in mammals, but have received little attention in non- ... Uneven Evolutionary Rates of Bradykinin B1 and B2 Receptors in Vertebrate Lineages. Bromée, Torun Uppsala University, ... The bradykinin and neuropeptide Y (NPY) receptors belong to the superfamily of G-protein coupled receptors (GPCRs). The GPCRs ...
http://uu.diva-portal.org/smash/record.jsf?pid=diva2:167267
*  IL-1{beta} Induced Transcriptional Up-regulation of Bradykinin B1 and B2 Receptors in Murine Airways.
IL-1 beta up-regulated bradykinin B-1 and B2 receptor expression and increased contractile response to bradykinin B-1 and B-2 ... IL-1 beta up-regulated bradykinin B-1 and B2 receptor expression and increased contractile response to bradykinin B-1 and B-2 ... IL-1{beta} Induced Transcriptional Up-regulation of Bradykinin B1 and B2 Receptors in Murine Airways.. Zhang, Yaping LU ; Adner ... In addition, IL-1 beta did not affect bradykinin B-1 and B-2 receptor mRNA stability. Remicade, an anti-TNF-a antibody, ...
https://lup.lub.lu.se/search/publication/164628
*  Bradykinin B1/B2 Receptor Agonist | MediLumine
Bradykinin B1/B2 Receptor Agonist. Bradykinin B1/B2 Receptor Agonist 344 USD ... Bradykinin Receptor Modulators *Bradykinin B2 Receptor Agonist. *Bradykinin B1 Receptor Agonist. *Bradykinin B1/B2 Receptor ... Côté J, Savard M, Neugebauer W, Fortin D, Lepage M, Gobeil F. Dual kinin B1 and B2 receptor activation provides enhanced blood- ... Receptor Modulators. -Systems and Accessories. Applications. User Guides / Application Notes / Posters. Videos. Services. Order ...
http://www.medilumine.com/bradykinin-b1b2-receptor-agonist/
*  Pharmaceutical Chemicals - Market Size, Market Share, Market Leaders, Demand Forecast, Sales, Company Profiles, Market Research...
7.9.3 Bradykinin B2 Receptor Antagonists. Bradykinin B2 Receptor Antagonists. $82.00. *. 7.9.4 Cardiac Glycosides. Cardiac ... 7.6 Angiotensin II Receptor Antagonists. Angiotensin II Receptor Antagonists. $82.00. *. Table , ANGIOTENSIN II ANTAGONIST ...
https://www.freedoniagroup.com/industry-study/pharmaceutical-chemicals-3280.htm
*  Compound Report Card
Bradykinin B2 receptor Homo sapiens 0.991 CHEMBL2622 Aldose reductase Rattus norvegicus 0.984 ...
https://www.ebi.ac.uk/chembldb/index.php/compound/inspect/CHEMBL1020
*  Medical education | The Medical Journal of Australia
Successful treatment of ACE inhibitor-induced angioedema with icatibant, a bradykinin B2 receptor antagonist ...
https://www.mja.com.au/journal/medical-education?page=6
*  MEDLINE Data Changes - 2015. NLM Technical Bulletin. 2014 Nov-Dec
Receptor, Bradykinin B1 /antagonists & inhibitors. Bradykinin B1 Receptor Antagonists. Receptor, Bradykinin B2 /antagonists & ... Receptors, Bradykinin /antagonists & inhibitors. Bradykinin Receptor Antagonists. Receptors, CCR5 /antagonists & inhibitors. ... Receptors, Islet Amyloid Polypeptide /agonists. Amylin Receptor Agonists. Receptors, Opioid /antagonists & inhibitors. Narcotic ... Receptor, Endothelin A /antagonists & inhibitors. Endothelin A Receptor Antagonists. Receptor, Endothelin B /antagonists & ...
https://www.nlm.nih.gov/pubs/techbull/nd14/nd14_medline_data_changes_2015.html
*  Blinded Safety & Efficacy Placebo Controlled Study of Icatibant for Angiotensin Converting Enzyme Inhibitor Induced Angioedema ...
Bradykinin B2 Receptor Antagonists. Bradykinin Receptor Antagonists. Complement Inactivating Agents. Immunosuppressive Agents. ... Bradykinin. Molecular Mechanisms of Pharmacological Action. Protease Inhibitors. Anti-Inflammatory Agents, Non-Steroidal. ...
https://clinicaltrials.gov/ct2/show/NCT01919801
*  The Effect of Ischaemic-Reperfusion and Remote Ischaemic Preconditioning in Man - A Bradykinin Dependent Pathway - Full Text...
Drug: bradykinin receptor antagonist (HOE-140) Systemic infusion of bradykinin receptor antagonist (HOE-140) ... Bradykinin. Kininogens. Icatibant. Bradykinin Receptor Antagonists. Vasodilator Agents. Cysteine Proteinase Inhibitors. ... Systemic infusion of bradykinin receptor antagonist (HOE-140).. Procedure: Forearm vascular study Forearm blood flow measured ... Procedure: Forearm vascular study Drug: Placebo Drug: bradykinin receptor antagonist (HOE-140) Not Applicable ...
https://clinicaltrials.gov/ct2/show/NCT00965393
*  Open-label, Single-arm Study to Assess the Pharmacokinetics, Safety, and Tolerability of a Single Subcutaneous Dose of...
Bradykinin B2 Receptor Antagonists. Bradykinin Receptor Antagonists. Complement Inactivating Agents. Immunosuppressive Agents. ... Bradykinin. Molecular Mechanisms of Pharmacological Action. Sensory System Agents. Physiological Effects of Drugs. Analgesics, ...
https://clinicaltrials.gov/ct2/show/NCT02045264?recr=Open&cond=%22Genetic+Diseases%2C+Inborn%22&rank=12
*  Efficacy and Safety Study of Intra-articular Multiple Doses of Icatibant in Patients With Painful Knee Osteoarthritis - Full...
Bradykinin B2 Receptor Antagonists. Bradykinin Receptor Antagonists. Molecular Mechanisms of Pharmacological Action. Complement ... Bradykinin. Anti-Inflammatory Agents, Non-Steroidal. Analgesics, Non-Narcotic. Analgesics. Sensory System Agents. Peripheral ...
https://clinicaltrials.gov/ct2/show/NCT00303056
*  Icatibant (Professional Patient Advice) - Drugs.com
Selective Bradykinin B2 Receptor Antagonist. Pharmacology. Icatibant is a selective competitive antagonist for the bradykinin B ... Icatibant inhibits bradykinin from binding at the B2 receptor, thereby treating the symptoms associated with acute attack. ... Patients with HAE have an absence or dysfunction of C1-esterase-inhibitor which leads to the production of bradykinin. The ... presence of bradykinin may cause symptoms of localized swelling, inflammation, and pain. ...
https://www.drugs.com/ppa/icatibant.html