Intracellular calcium regulates agrin-induced acetylcholine receptor c by Laura Jalso Megeath and Justin R. Fallon  "Intracellular calcium regulates agrin-induced acetylcholine receptor c" by Laura Jalso Megeath and Justin R. Fallon
Clamping intracellular calcium levels by loading with the fast chelator BAPTA inhibited agrin-induced AChR aggregation. In ... Early signal transduction events in agrin-mediated postsynaptic differentiation include activation of a receptor tyrosine ... kinase and phosphorylation of acetylcholine receptors (AChRs), but later steps in this pathway are unknown. Here, we have ... Agrin; Animals; Calcium; Chelating Agents; Chick Embryo; Egtazic Acid; Phosphorylation; *Receptor Aggregation; Receptors, ...
more infohttps://escholarship.umassmed.edu/oapubs/1180/
Agrin-induced Reorganization of Extracellular Matrix Components on Cultured Myotubes: Relationship to AChR Aggregation -...  Agrin-induced Reorganization of Extracellular Matrix Components on Cultured Myotubes: Relationship to AChR Aggregation -...
Acetylcholine receptors (AChRs) ~, for example, are packed into the synaptic membrane at densities approaching 15-20,000 per ... 1. Abbreviations used in this paper: AChR, acetyicholine receptor; HSPG, heparan sulfate proteoglycan. 1978; Burden et al., ... and type IV collagen on cultured chick myotubes during agrininduced aggregation of AChRs. Myotubes displayed significant ... induces the accumulation of acetylcholine receptors (AChRs) and other synaptic components into discrete patches on cultured ...
more infohttps://www.semanticscholar.org/paper/Agrin-induced-Reorganization-of-Extracellular-Matr-Ni/ac4b3f37de0e5c1bcc13ca40f16b18b7ad1e9204
Mast cells are best known for their function in hypersensitive reactions, - Synthesis and Structure-activity Relationship of...  Mast cells are best known for their function in hypersensitive reactions, - Synthesis and Structure-activity Relationship of...
When a multivalent antigen binds to IgE occupying the high affinity receptor for IgE (FcRI), receptor aggregation and following ... Mast cells are best known for their function in hypersensitive reactions, where aggregation of FcRI leads to the release of ... It provides previously been confirmed that the aggregation of FcRI can result in elevated success of mast cells (activation- ... additional recommending that account activation through these Fc-receptors contributes to mast cell success. Right here that ...
more infohttp://www.conferencedequebec.org/2018/01/09/mast-cells-are-best-known-for-their-function-in-hypersensitive-reactions/
Schwarte RC and Godfrey EW (2004), 
		
		
			Nitric oxide synthase activity is required for ... -
		
		Xenbase Paper
	  Schwarte RC and Godfrey EW (2004), Nitric oxide synthase activity is required for ... - Xenbase Paper
Inhibition of NOS reduced AChR aggregation at embryonic Xenopus NMJs by 50-90%, whereas overexpression of NOS increased AChR ... including acetylcholine receptors (AChRs). We examined whether nitric oxide synthase (NOS) activity is required for agrin- ... NOS inhibitors completely blocked agrin-induced AChR aggregation in cultured embryonic muscle cells. Application of NO donors ... induced aggregation of postsynaptic AChRs at the embryonic NMJ in vivo and in cultured muscle cells. ...
more infohttp://www.xenbase.org/literature/article.do?method=display&articleId=3108
IDEALS @ Illinois: Structural and Functional Aspects of Dystroglycan During Agrin -Mediated Acetylcholine Receptor Clustering...  IDEALS @ Illinois: Structural and Functional Aspects of Dystroglycan During Agrin -Mediated Acetylcholine Receptor Clustering...
Evidence points toward an indirect role for dystroglycan, a role which is important for the aggregation and stabilization of ... Structural and Functional Aspects of Dystroglycan During Agrin -Mediated Acetylcholine Receptor Clustering at the Mammalian ... Structural and Functional Aspects of Dystroglycan During Agrin -Mediated Acetylcholine Receptor Clustering at the Mammalian ... Structural and Functional Aspects of Dystroglycan During Agrin -Mediated Acetylcholine Receptor Clustering at the Mammalian ...
more infohttps://www.ideals.illinois.edu/handle/2142/84805
Herpes simplex virus thymidine kinase/ganciclovir-induced apoptosis involves ligand-independent death receptor aggregation and...  Herpes simplex virus thymidine kinase/ganciclovir-induced apoptosis involves ligand-independent death receptor aggregation and...
TK/GCV strongly induced CD95 receptor expression and CD95 receptor aggregation in the absence of CD95-L induction. CD95-L- ... FADD is recruited to death receptors of the TNF receptor family such as CD95, the TNF receptors, and TRAIL-DR5 upon activation ... Without aggregation of CD95, the few antibody molecules will bind to single receptors only, resulting in unappreciable amounts ... These results suggest that CD95 receptor aggregation in the absence of CD95-L may trigger the caspase cascade in TK/GCV therapy ...
more infohttps://www.pnas.org/content/96/15/8699?ijkey=d2a1f50621b758da69da161de5f83fc74064b7b1&keytype2=tf_ipsecsha
Identification of Erbin Interlinking MuSK and ErbB2 and Its Impact on Acetylcholine Receptor Aggregation at the Neuromuscular...  Identification of Erbin Interlinking MuSK and ErbB2 and Its Impact on Acetylcholine Receptor Aggregation at the Neuromuscular...
A hallmark of the postsynaptic apparatus is the aggregation of acetylcholine receptors (AChRs) (Sanes and Lichtman, 1999). ... 2004) Neuregulin inhibits acetylcholine receptor aggregation in myotubes. J Biol Chem 279:31622-31628. ... Identification of Erbin Interlinking MuSK and ErbB2 and Its Impact on Acetylcholine Receptor Aggregation at the Neuromuscular ... Identification of Erbin Interlinking MuSK and ErbB2 and Its Impact on Acetylcholine Receptor Aggregation at the Neuromuscular ...
more infohttp://www.jneurosci.org/content/30/19/6620
A Novel Variant in the Platelet Endothelial Aggregation Receptor-1 Gene Is Associated With Increased Platelet Aggregability |...  A Novel Variant in the Platelet Endothelial Aggregation Receptor-1 Gene Is Associated With Increased Platelet Aggregability |...
Platelet endothelial aggregation receptor 1 (PEAR1), a novel epidermal growth factor repeat-containing transmembrane receptor, ... A Novel Variant in the Platelet Endothelial Aggregation Receptor-1 Gene Is Associated With Increased Platelet Aggregability. J ... A Novel Variant in the Platelet Endothelial Aggregation Receptor-1 Gene Is Associated With Increased Platelet Aggregability ... Maximal aggregation to ADP was also reduced, but by a lesser amount. However, residual aggregation to all 3 agonists was ...
more infohttp://atvb.ahajournals.org/content/28/8/1484.long
PEAR1 elisa kit | Mouse platelet endothelial aggregation receptor 1 ELISA Kit-NP 001027585.1  PEAR1 elisa kit | Mouse platelet endothelial aggregation receptor 1 ELISA Kit-NP 001027585.1
Mouse platelet endothelial aggregation receptor 1 ELISA Kit-NP_001027585.1 (MBS9332849) product datasheet at MyBioSource, ELISA ... platelet endothelial aggregation receptor 1 (PEAR1), ELISA Kit. Also Known As Mouse Platelet endothelial aggregation receptor 1 ... platelet endothelial aggregation receptor 1 isoform a NCBI Official Synonym Full Names platelet endothelial aggregation ... Platelet endothelial aggregation receptor 1 UniProt Synonym Protein Names Jagged and Delta protein; Protein Jedi; Multiple ...
more infohttps://www.mybiosource.com/prods/ELISA-Kit/Mouse/platelet-endothelial-aggregation-receptor-1/PEAR1/datasheet.php?products_id=9332849
Cytosolic Fc receptor TRIM21 inhibits seeded tau aggregation | PNAS  Cytosolic Fc receptor TRIM21 inhibits seeded tau aggregation | PNAS
Cytosolic Fc receptor TRIM21 inhibits seeded tau aggregation. William A. McEwan, Benjamin Falcon, Marina Vaysburd, Dean Clift, ... 5 C-E). Thus, TRIM21 appears to be the only FcR expressed and functional in neurons, and therefore the sole receptor capable of ... TRIM21 is the only protective Fc receptor in SHSY-5Y neuroblastoma cells. (A) Levels of seeding in SHSY-5Y cells treated as ... 2013) Intracellular antibody-bound pathogens stimulate immune signaling via the Fc receptor TRIM21. Nat Immunol 14(4):327-336. ...
more infohttps://www.pnas.org/content/114/3/574
Pharmacological Evaluation of SKL-18287, a New Long-Acting Glucagon-Like Peptide-1 Receptor Agonist with Enhanced Aggregation...  Pharmacological Evaluation of SKL-18287, a New Long-Acting Glucagon-Like Peptide-1 Receptor Agonist with Enhanced Aggregation...
... receptor agonist, SKL-18287, (EC50: 1.2 and 0.13 nM for mouse and human, respectively) with extended in vivo half-life (T1/2 ... Pharmacological Evaluation of SKL-18287, a New Long-Acting Glucagon-Like Peptide-1 Receptor Agonist with Enhanced Aggregation ... Very recently, we have reported a new glucagon-like peptide-1 (GLP-1) receptor agonist, SKL-18287, (EC50: 1.2 and 0.13 nM for ... Prasad-Reddy L, Isaacs D (2015) A clinical review of GLP-1 receptor agonists: efficacy and safety in diabetes and beyond. Drugs ...
more infohttps://rd.springer.com/article/10.1007%2Fs10989-018-9777-7
JCI -
Activation of the murine EP3 receptor for PGE2 inhibits cAMP production and promotes platelet aggregation  JCI - Activation of the murine EP3 receptor for PGE2 inhibits cAMP production and promotes platelet aggregation
... the EP2 receptor, the EP4 receptor, and some isoforms of the EP3 receptor (9). This raised the possibility that these receptors ... or EP3 receptor. Only loss of the IP receptor affected the ability of PGE2 to inhibit platelet aggregation. To observe this ... inhibition of platelet aggregation by Gs-coupled receptors such as the IP receptor is associated with increased intracellular ... induced aggregation in platelets lacking both the IP and TP receptors. (d) Comparison of aggregation induced by 5 μM ADP in the ...
more infohttps://www.jci.org/articles/view/10881
Potentiation of clopidogrel active metabolite formation by rifampicin leads to greater P2Y12 receptor blockade and inhibition...  Potentiation of clopidogrel active metabolite formation by rifampicin leads to greater P2Y12 receptor blockade and inhibition...
Increasing numbers of unblocked receptors were required for an aggregation response with a decreasing concentration of ADP. PA ... Clopidogrel AM levels were determined over 4 h after the clopidogrel loading dose and unblocked P2Y(12) receptor number was ... active metabolite formation by rifampicin leads to greater P2Y12 receptor blockade and inhibition of platelet aggregation after ... Rifampicin increases the inhibitory effect of clopidogrel on platelet aggregation (PA). We studied the response to clopidogrel ...
more infohttp://umu.diva-portal.org/smash/record.jsf?pid=diva2%3A865459
Triggering Receptor Expressed on Myeloid cells-1: a new player in platelet aggregation. | Sigma-Aldrich  Triggering Receptor Expressed on Myeloid cells-1: a new player in platelet aggregation. | Sigma-Aldrich
Triggering Receptor Expressed on Myeloid cells-1: a new player in platelet aggregation.. [Lucie Jolly, Jeremie Lemarie, Kevin ... Triggering Receptor Expressed on Myeloid cells-1 (TREM-1) is an immunoreceptor initially known to be expressed on neutrophils ... Another member of the TREM family, The Triggering receptor expressed on myeloid cells Like Transcript-1 (TLT-1) is exclusively ... Pharmacologic inhibition of TREM-1 reduces platelet activation as well as platelet aggregation induced by collagen, ADP, and ...
more infohttps://www.sigmaaldrich.com/catalog/papers/28837205
A soluble form of the Mer receptor tyrosine kinase inhibits macrophage clearance of apoptotic cells and platelet aggregation |...  A soluble form of the Mer receptor tyrosine kinase inhibits macrophage clearance of apoptotic cells and platelet aggregation |...
A soluble form of the Mer receptor tyrosine kinase inhibits macrophage clearance of apoptotic cells and platelet aggregation. ... A soluble form of the Mer receptor tyrosine kinase inhibits macrophage clearance of apoptotic cells and platelet aggregation. ... A soluble form of the Mer receptor tyrosine kinase inhibits macrophage clearance of apoptotic cells and platelet aggregation ... Soluble receptors and their membrane-bound counterparts can act agonistically, as is the case with the IL-6 receptor.49 However ...
more infohttp://www.bloodjournal.org/content/109/3/1026?ijkey=dec10cd92b8dc1b1b32bef6f2bb593c875d634dd&keytype2=tf_ipsecsha&sso-checked=true
Beta 2-integrin and L-selectin are obligatory receptors in neutrophil aggregation [see comments] | Blood | American Society of...  Beta 2-integrin and L-selectin are obligatory receptors in neutrophil aggregation [see comments] | Blood | American Society of...
Beta 2-integrin and L-selectin are obligatory receptors in neutrophil aggregation [see comments] SI Simon SI Simon ... Beta 2-integrin and L-selectin are obligatory receptors in neutrophil aggregation [see comments]. Blood 1993; 82 (4): 1097-1106 ... We have recently found that antibodies to L-selectin, the homing receptor on neutrophils, are as effective as those to beta 2- ... We examined the aggregation of neutrophils from patients genetically deficient in beta 2-integrin and clinically leukocyte ...
more infohttps://ashpublications.org/blood/article/82/4/1097/170680/Beta-2integrin-and-Lselectin-are-obligatory
Integrins can collaborate with growth factors for phosphorylation of receptor tyrosine kinases and MAP kinase activation: roles...  Integrins can collaborate with growth factors for phosphorylation of receptor tyrosine kinases and MAP kinase activation: roles...
... roles of integrin aggregation and occupancy of receptors.. S Miyamoto, H Teramoto, J S Gutkind, K M Yamada ... roles of integrin aggregation and occupancy of receptors. ... collaborate with growth factors for phosphorylation of receptor ... Integrins can collaborate with growth factors for phosphorylation of receptor tyrosine kinases and MAP kinase activation: ...
more infohttp://jcb.rupress.org/content/135/6/1633/tab-article-info
Integrins can collaborate with growth factors for phosphorylation of receptor tyrosine kinases and MAP kinase activation: roles...  Integrins can collaborate with growth factors for phosphorylation of receptor tyrosine kinases and MAP kinase activation: roles...
... roles of integrin aggregation and occupancy of receptors.. S Miyamoto, H Teramoto, J S Gutkind, K M Yamada ... roles of integrin aggregation and occupancy of receptors. ... collaborate with growth factors for phosphorylation of receptor ... Integrins can collaborate with growth factors for phosphorylation of receptor tyrosine kinases and MAP kinase activation: ...
more infohttp://jcb.rupress.org/content/135/6/1633/tab-pdf
AID 212287 - In vitro thromboxane A2 receptor antagonism through inhibition of U-46619 induced platelet aggregation in human...  AID 212287 - In vitro thromboxane A2 receptor antagonism through inhibition of U-46619 induced platelet aggregation in human...
In vitro thromboxane A2 receptor antagonism through inhibition of U-46619 induced platelet aggregation in human whole blood. ...
more infohttps://pubchem.ncbi.nlm.nih.gov/bioassay/212287
Abstract 1699: Differential aggregation rates and therapeutic response of pancreatic cancer cell lines to sigma-2 receptor...  Abstract 1699: Differential aggregation rates and therapeutic response of pancreatic cancer cell lines to sigma-2 receptor...
Differential aggregation rates and therapeutic response of pancreatic cancer cell lines to sigma-2 receptor activation in 3D ... Abstract 1699: Differential aggregation rates and therapeutic response of pancreatic cancer cell lines to sigma-2 receptor ... Abstract 1699: Differential aggregation rates and therapeutic response of pancreatic cancer cell lines to sigma-2 receptor ... Abstract 1699: Differential aggregation rates and therapeutic response of pancreatic cancer cell lines to sigma-2 receptor ...
more infohttp://cancerres.aacrjournals.org/content/75/15_Supplement/1699