Control of brown adipose tissue thermogenesis by pituitary-adrenal hormones in the obese Zucker (fa/fa) rat - ePrints Soton
Control of brown adipose tissue thermogenesis by pituitary-adrenal hormones in the obese Zucker (fa/fa) rat ... Control of brown adipose tissue thermogenesis by pituitary-adrenal hormones in the obese Zucker (fa/fa) rat ... Control of brown adipose tissue thermogenesis by pituitary-adrenal hormones in the obese Zucker (fa/fa) rat ... Al-Baker, Ibtisam (1985) Control of brown adipose tissue thermogenesis by pituitary-adrenal hormones in the obese Zucker (fa/fa ...
Isoform-Specific Regulation of 5′ AMP-Activated Protein Kinase in Skeletal Muscle From Obese Zucker (fa/fa) Rats in Response to...
The body weight of 11-week-old obese Zucker rats was significantly greater than that of age-matched lean rats (393 ± 7 vs. 267 ... 59.4 ± 2.1 mg, obese versus lean rats; P , 0.05). Obese Zucker rats displayed marked glucose intolerance, with blood glucose ... Obese male Zucker (fa/fa) rats (aged 11-12 weeks) and lean littermates were purchased from Charles River (Uppsala, Sweden) and ... Isoform-Specific Regulation of 5′ AMP-Activated Protein Kinase in Skeletal Muscle From Obese Zucker (fa/fa) Rats in Response to ...
Expression of fourteen novel obesity-related genes in zucker diabetic fatty rats - University of Regensburg Publication Server
... the mesenterium and subcutaneum as well as the hypothalamus of obese Zucker diabetic fatty (ZDF) and Zucker lean (ZL) rats at ... Expression of fourteen novel obesity-related genes in zucker diabetic fatty rats ... However, LYPLAL1, TFAP2B, SEC16B and FAIM2 were significantly lower expressed in the kidney fat of ZDF than ZL rats. NEGR1 was ... Interestingly, the expression pattern in the hypothalamus showed no differences between obese ZDF and lean ZL rats. ...
Mixed Effects Modeling Using Stochastic Differential Equations: Illustrated by Pharmacokinetic Data of Nicotinic Acid in Obese...
A DECREASED BRAIN-STEM CONTENT OF GABA MEDIATES HYPERINSULINEMIA IN OBESE ZUCKER RATS
By contrast no difference was observed between obese and lean rats in the GABAergic system of pancreas. Moreover Zucker rats ... By contrast no difference was observed between obese and lean rats in the GABAergic system of pancreas. Moreover Zucker rats ... A DECREASED BRAIN-STEM CONTENT OF GABA MEDIATES HYPERINSULINEMIA IN OBESE ZUCKER RATS. SQUADRITO, Francesco;CUCINOTTA, Domenico ... in obese rats, while the same therapeutic approach did not affect this parameter in lean rats. Furthermore sodium valproate ...
Volume 33 Issue 9, September 2010
Altered nitroxidergic and NMDA receptor-mediated modulation of baroreflex-mediated heart rate in obese Zucker rats *Jwo-Sheng ... Characterization of the L-arginine-NO-cGMP pathway in spontaneously hypertensive rat platelets: the effects of pregnancy * ... Combination therapy with irbesartan and efonidipine for attenuation of proteinuria in Dahl salt-sensitive rats *Shinji Takai ...
Laboratory rat - Wikipedia
Zucker, pioneer researchers in the study of the genetics of obesity. There are two types of Zucker rat: a lean Zucker rat, ... Zucker rat or Zucker diabetic fatty rat (ZDF rat), which is actually a recessive trait (fa/fa) of the leptin receptor, capable ... This and the Lewis rat are well-known stocks developed from Wistar rats. The Zucker rat was bred to be a genetic model for ... The biobreeding rat (a.k.a. the biobreeding diabetes-prone rat or BBDP rat) is an inbred strain that spontaneously develops ...
Rosiglitazone prevents ischaemic injury in the obese Zucker rat heart - Oxford Cardiovascular Science
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10 slices from six rats; p , 0.05 at 1.3-1.5×, PLSD) (Fig. 7A). Moreover, the D:Non-D EPSP ratio in rats deprived for 4-6 d ... Zucker RS, Regehr WG (2002) Short-term synaptic plasticity. Annu Rev Physiol 64:355-405. ... rats, we deprived rats for just 2 d beginning at P20. This brief deprivation did not alter input-output curves in deprived ... 2003); n = 11 D column cells, 11 non-D column cells, six slices, five rats; 21-25 d of age] (Fig. 1F). The D:Non-D EPSP ratio ...
Melatonin administration in diabetes: Regulation of plasma Cr, V, and Mg in young male Zucker diabetic fatty rats<...
... in Zucker diabetic fatty (ZDF) and Zucker lean (ZL) rats. At the age of 6 weeks, ZDF (n = 30) and ZL (n = 30) groups were each ... in Zucker diabetic fatty (ZDF) and Zucker lean (ZL) rats. At the age of 6 weeks, ZDF (n = 30) and ZL (n = 30) groups were each ... in Zucker diabetic fatty (ZDF) and Zucker lean (ZL) rats. At the age of 6 weeks, ZDF (n = 30) and ZL (n = 30) groups were each ... in Zucker diabetic fatty (ZDF) and Zucker lean (ZL) rats. At the age of 6 weeks, ZDF (n = 30) and ZL (n = 30) groups were each ...
Leptin receptor defect with diabetes causes skeletal muscle atrophy in female obese Zucker rats where peculiar depots networked...
Tibialis anterior muscles of 45-week-old female obese Zucker rats with defective leptin receptor and non-insulin dependent ... Leptin receptor defect with diabetes causes skeletal muscle atrophy in female obese Zucker rats where peculiar depots networked ... Leptin receptor defect with diabetes causes skeletal muscle atrophy in female obese Zucker rats where peculiar depots networked ... Leptin receptor defect with diabetes causes skeletal muscle atrophy in female obese Zucker rats where peculiar depots networked ...
Prediction of Methionine and Homocysteine levels in Zucker diabetic fatty (ZDF) rats as a T2DM animal model after consumption...
... following the development of a mathematical model for MMC in Zucker Diabetic Fatty (ZDF) rats, as a representative T2DM animal ... The levels of methionine and homocysteine were elevated approximately two- and three-fold, respectively, in ZDF rats, while ... there were no changes observed in the normal control rats. These results can be interpreted to mean that both methionine and ... performed simulations to compare the changes in plasma methionine and homocysteine concentrations between ZDF and normal rats, ...
Improved glucose homeostasis in male obese zucker rats coincides with enhanced baroreflexes and activation of the nucleus...
Hippocampal insulin resistance and cognitive dysfunction | Nature Reviews Neuroscience
Genetically obese Zucker rats have abnormally low brain insulin content. Life Sci. 36, 627-633 (1985). ... Astrogliosis in the brain of obese Zucker rat: a model of metabolic syndrome. Neurosci. Lett. 543, 136-141 (2013). ... Gerges, N. Z., Aleisa, A. M. & Alkadhi, K. A. Impaired long-term potentiation in obese Zucker rats: possible involvement of ... Memory impairment in obese Zucker rats: an investigation of cognitive function in an animal model of insulin resistance and ...
Dr. Alice Liu M.D., Endocrinologist in San Carlos, CA | Sutter Health
Differential adipogenic and inflammatory properties of small adipocytes in Zucker Obese and Lean rats. *Article ...
HORMONAL-CONTROL OF GROWTH IN THE GENETICALLY-OBESE ZUCKER RAT .1. LINEAR GROWTH, PLASMA INSULIN-LIKE GROWTH FACTOR-I (IGP-I)...
The genetically obese Zucker rat is a widely used model of early-onset obesity. Like obese children, these obese rats are ... In the present study, we investigated linear growth and its hormonal control in Zucker rats (male and female) from 4-20 weeks ... HORMONAL-CONTROL OF GROWTH IN THE GENETICALLY-OBESE ZUCKER RAT .1. LINEAR GROWTH, PLASMA INSULIN-LIKE GROWTH FACTOR-I (IGP-I) ... HORMONAL-CONTROL OF GROWTH IN THE GENETICALLY-OBESE ZUCKER RAT .1. LINEAR GROWTH, PLASMA INSULIN-LIKE GROWTH FACTOR-I (IGP-I) ...
Biblio | Page 4 | Linus Pauling Institute | Oregon State University
Rats, Zucker. Legette LCL, Luna AYMoreno, Reed RL, Miranda CL, Bobe G, Proteau RR, Stevens JF. 2013. Xanthohumol lowers body ... Xanthohumol lowers body weight and fasting plasma glucose in obese male Zucker fa/fa rats.. Phytochemistry. 91:236-41. ... Xanthohumol lowers body weight and fasting plasma glucose in obese male Zucker fa/fa rats.. Phytochemistry. 91:236-41. ... Xanthohumol lowers body weight and fasting plasma glucose in obese male Zucker fa/fa rats.. Phytochemistry. 91:236-41. ...
JCI - Protein kinase C is increased in the liver of humans and rats with non-insulin-dependent diabetes mellitus: an alteration...
The Zucker diabetic fatty rat offered such a model system. Immunodetectable membrane PKC-alpha, -beta, -epsilon, and -zeta were ... Protein kinase C is increased in the liver of humans and rats with non-insulin-dependent diabetes mellitus: an alteration not ... Protein kinase C is increased in the liver of humans and rats with non-insulin-dependent diabetes mellitus: an alteration not ... Normalization of circulating glucose in the rat model by either insulin or phlorizin treatment did not result in a reduction in ...
Febuxostat Attenuates Renal Damage besides Exerting Hypouricemic Effect in Streptozotocin-Induced Diabetic Rats
Sham-injected rats served as controls. The control and diabetic rats were treated with and without febuxostat for 8 weeks, ... Rat livers were extracted for detecting gene expression, content, and bioactivity of XO.,i, Results,/i,. Diabetic rats showed ... induced diabetic rats.,i, Methods,/i,. Diabetes was induced by the intraperitoneal injection of STZ in male Sprague-Dawley rats ... in these rats. Although hepatic gene expression, content, and activity of XO increased significantly in diabetic rats, ...
Anti-diabetic activity of chromium picolinate and biotin in rats with type 2 diabetes induced by high-fat diet and...
Anti-diabetic activity of chromium picolinate and biotin in rats with type 2 diabetes induced by high-fat diet and ... Pioglitazone induces in vivo adipocyte differentiation in the obese Zucker fa/fa rat. Diabetes 46, 1393-1399.Google Scholar ... The rats were divided into five groups as follows: (1) non-diabetic rats fed a regular diet; (2) diabetic rats fed a HFD; (3) ... 2-fold in diabetic control rats, compared with rats fed a regular diet (P= 0·0001). Diabetic rats fed a diet supplemented with ...
NIOSHTIC-2 Search Results - Full View
Lean Zucker rats have a normal metabolic profile, while obese Zucker rats display symptoms of metabolic disorder or Type II ... This study examined the effects of vibration in obese and lean rats. Zucker rats were exposed to 4h of vibration for 10 ... Obese Zucker rats displayed very few changes in sensorineural function. However they did display significant changes in ... The changes in transcript levels suggested that obese Zucker rats had some level of sensory nerve injury prior to exposure, and ...
Frontiers | Lipid Oxidation Assessed by Indirect Calorimetry Predicts Metabolic Syndrome and Type 2 Diabetes
Profiling of Zucker diabetic fatty rats in their progression to the overt diabetic state. Metabolism (2000) 49:684-8. doi: ... In another study, ZDF rats displayed a significantly higher RQ than their lean littermates during hyperinsulinemia and, as the ... of muscle carnitine palmitoyltransferase-1 promotes intramyocellular lipid accumulation and insulin resistance in rats. ...
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Tissue-Specific Oxidative Stress Modulation by Exercise: A Comparison between MICT and HIIT in an Obese Rat Model
... on the pro/antioxidant status of different tissues in obese Zucker rats. ,i,Methods,/i,. Eight-week-old male Zucker rats (,i,fa ... on the pro/antioxidant status of different tissues in obese Zucker rats. Methods. Eight-week-old male Zucker rats (fa/fa, ) ... In this study, we analyzed the effects of MICT and HIIT in Zucker rats (fa/fa). This animal model of obesity is the best known ... Seventy-five adult (8-week-old) male Zucker (fa/fa) rats were purchased from Charles River and were housed individually in an ...
Dr. Graham Holloway | Human Health & Nutritional Sciences
Subcellular Lipid Droplet Distribution in Red and White Muscles in the Obese Zucker Rat. Diabetologia. 2012; 55(2):479-88.. ... Decrease Blood Pressure and Prevent Diastolic Dysfunction in Obese Zucker Rats. Journal of Physiology. 595(13): 4351-4364, 2017 ... Submaximal ADP-Stimulated Respiration is Impaired in ZDF Rats and Recovered by Resveratrol. J. Physiol. 2013; 591 (Pt 23):6089- ... LA and ALA Prevent Glucose Intolerance in Obese Male Rats without Reducing Reactive Lipid Content, but Cause Tissue-Specific ...
The Role of Serotonin in Eating Disorders | SpringerLink
Altered serotonin metabolism in hypothalamic paraventricular nucleus of obese Zucker rats. Acta Physiologica Scandinavica 154( ... dopamine and 5-hydroxytryptamine in rat brain synaptosomes, rat heart and human blood platelets. Biochemical Pharmacology 26: ... Massi M, Marini S. Effect of the 5-HT2 antagonist ritanserin on food intake and on 5-HT-induced anorexia in the rat. ... Evidence that central 5-HT2 receptors do not play an important role in the anorectic activity of d-fenfluramine in the rat. ...
Profile | University of Otago
Suppression of pulsatile luteinizing hormone secretion but not luteinizing hormone surge in leptin resistant obese Zucker rats ... Ladyman, S. R., Sapsford, T. J., & Grattan, D. R. (2011). Loss of acute satiety response to cholecystokinin in pregnant rats. ... Ladyman, S. R. (2008). Leptin resistance during pregnancy in the rat. Journal of Neuroendocrinology, 20(269), 269-277. doi: ... in the rat hypothalamus is associated with leptin resistance during pregnancy. Endocrinology, 145(8), 3704-3711. ...
Nitric Oxide Enhancer | GreenMedInfo | Pharmacological Action
... extract in comparison to regular pomegranate juice and seed oil on nitric oxide and arterial function in obese Zucker rats.Jul ... L-arginine has a beneficial effect on the nitric-oxide producing pathway in rats treated with alloxan.Nov 01, 2007. ... The protective effects of Astragaloside Ⅳ on diastolic function of rat thoracic aortic rings impaired by microvesicles.Feb 07, ... Garlic and onion attenuates vascular inflammation and oxidative stress in fructose-fed rats.Jan 01, 2011. ...
Nutrients | Free Full-Text | Polycystic Ovary Syndrome in Insulin-Resistant Adolescents with Obesity: The Role of Nutrition...
Kusano, S.; Abe, H. Antidiabetic activity of white skinned sweet potato (Ipomoea batatas L.) in obese Zucker fatty rats. Biol. ... Prasad, K. Secoisolariciresinol diglucoside from flaxseed delays the development of type 2 diabetes in Zucker rat. J. Lab. Clin ... Xu, J.; Dun, J.; Yang, J.; Zhang, J.; Lin, Q.; Huang, M.; Ji, F.; Huang, L.; You, X.; Lin, Y. Letrozole Rat Model Mimics Human ... Larner, J.; Huang, L.C.; Schwartz, C.F.; Oswald, A.S.; Shen, T.Y.; Kinter, M.; Tang, G.Z.; Zeller, K. Rat liver insulin ...