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*  Frontiers | Obesity in the Otsuka Long Evans Tokushima Fatty Rat: Mechanisms and Discoveries | Nutrition
The current review focuses on the Otsuka Long Evans Tokushima Fatty (OLETF) rat obesity model. Since its recognition in the ... Study of the OLETF rats has revealed important differences in the organization of the DMH in rats and mice and elucidated ... Study of the OLETF rats has revealed important differences in the organization of the DMH in rats and mice and elucidated ... OLETF rats have a deficit in their ability to limit the size of meals and in contrast to CCK1 receptor knock-out mice, do not ...
https://www.frontiersin.org/articles/10.3389/fnut.2016.00021/full
*  Lack of vasopressin-independent upregulation of AQP-2 gene expression in homozygous Brattleboro rats | Regulatory, Integrative...
... homozygous Brattleboro rats, 12-h dehydration; lanes 5 and6, Long-Evans rats, control;lanes 7 and8, Long-Evans rats, 64-h ... and these values were much less than those of Long-Evans rats. Tissue content of AQP-2 was greater in the dehydrated Long-Evans ... There was a positive correlation (r = 0.51,P , 0.01) in the Long-Evans rats but not in the homozygous Brattleboro rats (r = ... Northern blot analysis of expression of rat AQP-2 mRNA in kidney of homozygous Brattleboro and Long-Evans rats.A: homozygous ...
http://ajpregu.physiology.org/content/277/2/R427
*  Effects of Haemorrhage in Rats Lacking Vasopressin (Brattleboro Strain): Influence of Naloxone | Clinical Science
Long Evans) rats.. 2. To produce similar reductions in blood pressure, less blood had to be taken from the Brattleboro rats ... the Brattleboro rats remained hypotensive at a time when the Long Evans rats were normotensive. These findings suggest that ... blood pressure recovery was slower in Brattleboro rats than in Long Evans rats. Naloxone did not affect the response to rapid ... there was no difference between the recovery of blood pressure in Brattleboro rats and Long Evans rats. Naloxone improved blood ...
http://www.clinsci.org/content/65/1/19
*  Oral administration of green algae, Euglena gracilis, inhibits hyperglycemia in OLETF rats, a model of spontaneous type 2...
... rats. OLETF rats were fed an AIN-93 M diet containing cellulose, Euglena, or paramylon for 10 weeks. Long-Evans Tokushima ... the effects of Euglena and paramylon on hyperglycemia were examined in Otsuka Long-Evans Tokushima fatty (OLETF; type 2 ... rats. OLETF rats were fed an AIN-93 M diet containing cellulose, Euglena, or paramylon for 10 weeks. Long-Evans Tokushima ... In the present study, the effects of Euglena and paramylon on hyperglycemia were examined in Otsuka Long-Evans Tokushima fatty ...
http://pubs.rsc.org/en/Content/ArticleLanding/FO/2016/C6FO00606J
*  Role of cholecystokinin (CCK)-A receptor for pancreatic growth after weaning: a study in a new rat model without gene...
... rats, which have been established as an animal model of non-insulin-dependent diabetes mellitus, show no expression of the ... This work extends a recent observation that Otsuka Long-Evans Tokushima Fatty (OLETF) ... Long-Evans Tokushima; LETO) rats. The pancreatic wet weight increased significantly with age in both OLETF and LETO rats but ... This work extends a recent observation that Otsuka Long-Evans Tokushima Fatty (OLETF) rats, which have been established as an ...
http://www.ndsl.kr/ndsl/search/detail/article/articleSearchResultDetail.do?cn=NART00001743
*  Long Evans Outbred Rat Model | Taconic Biosciences
Long Evans rats are used in neurological, toxicological and ophthalmologic studies and are preferred for surgeries requiring ... Long and Dr. Evans in 1915 by intercrossing Wistar Institute white female rats to wild grey male rats. Simonsen Laboratories ... Reported higher resistance to respiratory problems than outbred albino rats, making the Long Evans rat the preferred stock for ... Fluid and electrolyte handling in Long Evans and Brattleboro rats following injection of polyethylene glycol. ...
https://www.taconic.com/rat-model/long-evans
*  Poly-arginine Peptide R18D Reduces Neuroinflammation and Functional Deficits Following Traumatic Brain Injury in the Long-Evans...
... following TBI in the Long-Evans rat. Following a closed-head impact delivered via a weight-drop apparatus, peptide was ... Peptide R18D Reduces Neuroinflammation and Functional Deficits Following Traumatic Brain Injury in the Long-Evans Rat. ... Marmarou A, Foda MA, van den Brink W et al (1994) A new model of diffuse brain injury in rats. Part I: Pathophysiology and ... Taupin V, Toulmond S, Serrano A et al (1993) Increase in IL-6, IL-1 and TNF levels in rat brain following traumatic lesion: ...
https://link.springer.com/article/10.1007%2Fs10989-018-09799-8
*  Temporal Thresholds for Infarction and Hypothermic Protection in Long-Evans Rats. Factors Affecting Apparent Reperfusion...
Temporal Thresholds for Infarction and Hypothermic Protection in Long-Evans Rats. Factors Affecting Apparent Reperfusion Injury ... Temporal Thresholds for Infarction and Hypothermic Protection in Long-Evans Rats. Factors Affecting Apparent Reperfusion Injury ... Temporal Thresholds for Infarction and Hypothermic Protection in Long-Evans Rats. Factors Affecting Apparent Reperfusion Injury ... Temporal Thresholds for Infarction and Hypothermic Protection in Long-Evans Rats. Factors Affecting Apparent Reperfusion Injury ...
http://stroke.ahajournals.org/content/early/2008/01/03/STROKEAHA.107.495788
*  The inhibitory effects of corncob bedding on sexual behavior in the ovariectomized Long-Evans rat treated with estradiol...
The inhibitory effects of corncob bedding on sexual behavior in the ovariectomized Long-Evans rat treated with estradiol ... The inhibitory effects of corncob bedding on sexual behavior in the ovariectomized Long-Evans rat treated with estradiol ... The inhibitory effects of corncob bedding on sexual behavior in the ovariectomized Long-Evans rat treated with estradiol ...
https://www.journals.elsevier.com/hormones-and-behavior/audioslides-gallery/the-inhibitory-effects-of-corncob-bedding-on-sexual-behavior
*  Long-term colony housing in Long Evans rats: immunological, ho...
Long-term colony housing in Long Evans rats: immunological, hormonal, and behavioral consequences.: The distribution pattern ... Long-term colony housing in Long Evans rats: immunological, hormonal, and behavioral consequences.. Authors * Stefanski, V ... pattern and the function of blood immune cells were investigated for 10 weeks in three mixed-sex colonies of Long Evans rats. ... The persistency of changes in subdominant males offers the opportunity to investigate the effects of long-term immuno- ...
https://www.mysciencework.com/publication/show/long-term-colony-housing-long-evans-rats-immunological-hormonal-behavioral-consequences-cfee646f
*  KAKEN - Research Projects | Protective effects of Lycopene on hepatocarcinogenesis in Long-Evans Cinnamon rats (KAKENHI-PROJECT...
A high incidence of hepatocellular carcinoma (HCC) in long surviving Long Evans Cinnamon (LEC) rats was reported. In order to ... Protective effects of Lycopene on hepatocarcinogenesis in Long-Evans Cinnamon rats. Research Project ... All rats were sacrificed in 76 week life for autopsy and histopathological examination was performed. Fifty five percent (1 1/ ... Percentage of HCC bearing rats did not differ among the three groups. Number of preneoplastic lesions stained with GST-P per ...
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-10670480/
*  Microbiology Society Journals | Isolation and molecular characterization of group B Streptococcus from laboratory Long-Evans...
We describe polymicrobial sepsis including GBS in two gravid adult female Long-Evans rats experiencing acute mortality from a ... Phylogenetic analyses revealed that one rat-derived GBS strain was more closely related to human-derived strains than other rat ... The rat strains have virulence factors known to contribute to pathogenicity, and shared serotypes with human invasive isolates ... To our knowledge, this is the first investigation of genotypic and phenotypic features of rat-derived GBS strains and their ...
https://jmm.microbiologyresearch.org/content/journal/jmm/10.1099/jmm.0.000627
*  Clozapine N-Oxide Administration Produces Behavioral Effects in Long-Evans Rats: Implications for Designing DREADD Experiments ...
Male Long-Evans rats (Harlan Laboratories; rats were bred in our facilities) weighing 300-330 g at the start of behavioral ... Using wild-type male Long-Evans rats, we investigated the effects of CNO at commonly used doses (1-5 mg/kg) on acoustic startle ... The results from these studies show that CNO, in male Long-Evans rats, is not an inert ligand. Regardless of whether the ... Our experiments were conducted in adult male Long-Evans rats, which, in addition to being a common outbred strain used in many ...
http://www.eneuro.org/content/3/5/ENEURO.0219-16.2016
*  Alpha-lipoic acid attenuates cardiac fibrosis in Otsuka Long-Evans Tokushima Fatty rats | Cardiovascular Diabetology | Full Text
... rats. Animals were separated into non-diabetic Long-Evans Tokushima Otsuka (LETO) rats and diabetes-prone OLETF rats with or ... signalling was lower in OLETF rats than in LETO rats, and that ALA treatment increased the signalling in OLETF rats. ... were expressed at higher levels in OLETF rat hearts than in LETO rat hearts, and the levels of these factors were decreased by ... and fibrosis in the hearts of Otsuka Long-Evans Tokushima fatty (OLETF) ...
https://cardiab.biomedcentral.com/articles/10.1186/1475-2840-11-111
*  Hypoglycemic Effects of Fermented Chaga Mushroom (Inonotus obliquus) in the Diabetic Otsuka Long-Evans Tokushima Fatty (OLETF)...
... on the OLETF rat were compared to the normal diet fed OLETF rat and the non-diabetic Long-Evans Tokushima Otsuka (LETO) rat. ... on the OLETF rat were compared to the normal diet fed OLETF rat and the non-diabetic Long-Evans Tokushima Otsuka (LETO) rat. ... These studies were conducted using the genetically manipulated diabetic Otsuka Long-Evans Tokushima Fatty (OLETF) rat. The ... These studies were conducted using the genetically manipulated diabetic Otsuka Long-Evans Tokushima Fatty (OLETF) rat. The ...
http://agris.fao.org/agris-search/search.do?request_locale=en&recordID=KR2007000481&sourceQuery=&query=&sortField=&sortOrder=&agrovocString=&advQuery=¢erString=&enableField=&aggregatorField=&typeresultsField=
*  The Effects of Stress and Nicotine on Heart Histopathology Differ in Male and Female Sprague-Dawley and Long-Evans Rats ::...
The Effects of Stress and Nicotine on Heart Histopathology Differ in Male and Female Sprague-Dawley and Long-Evans Rats ... The Effects of Stress and Nicotine on Heart Histopathology Differ in Male and Female Sprague-Dawley and Long-Evans Rats. ...
http://digitalcollections.lrc.usuhs.edu/cdm/ref/collection/p15459coll1/id/11727/
*  Effect of long-term treatment with royal jelly on insulin resistance in Otsuka Long-Evans Tokushima Fatty (OLETF) rats<...
Effect of long-term treatment with royal jelly on insulin resistance in Otsuka Long-Evans Tokushima Fatty (OLETF) rats. In: ... Effect of long-term treatment with royal jelly on insulin resistance in Otsuka Long-Evans Tokushima Fatty (OLETF) rats. / ... Effect of long-term treatment with royal jelly on insulin resistance in Otsuka Long-Evans Tokushima Fatty (OLETF) rats. ... title = "Effect of long-term treatment with royal jelly on insulin resistance in Otsuka Long-Evans Tokushima Fatty (OLETF) rats ...
https://okayama.pure.elsevier.com/en/publications/effect-of-long-term-treatment-with-royal-jelly-on-insulin-resista
*  Long Term Temporal Changes in Structure and Function of Rat Visual System After Blast Exposure | IOVS | ARVO Journals
Long-Evans rats (n = 54; 399 ± 68 g; age, 10-14 weeks) were administered carprofen orally (20 mg) 1 day before and 1 day after ... Methods: Male Long-Evans rats were exposed to 230 kPa side-on primary blast overpressure using a compressed air driven shock ... DeMar J, Sharrow K, Hill M, Berman J, Oliver T, Long J. Effects of primary blast overpressure on retina and optic tract in rats ... Long Term Temporal Changes in Structure and Function of Rat Visual System After Blast Exposure ...
https://iovs.arvojournals.org/article.aspx?articleid=2670449
*  Uridine modulates neuronal activity and inhibits spike-wave discharges of absence epileptic Long Evans and Wistar Albino Glaxo...
... between 150-270min and 90-270min in Long Evans and WAG/Rij rats, respectively. The effect of Urd was long-lasting in both rat ... used to provide evidence for the presence of Urd-sensitive neurons in the thalamus and the cerebral cortex of Long Evans rats. ... neuronal activity and inhibits spike-wave discharges of absence epileptic Long Evans and Wistar Albino Glaxo/Rijswijk rats ... neuronal activity and inhibits spike-wave discharges of absence epileptic Long Evans and Wistar Albino Glaxo/Rijswijk rats. ...
http://real.mtak.hu/17108/
*  Frontiers | Long-Term Effects of Intermittent Adolescent Alcohol Exposure in Male and Female Rats | Behavioral Neuroscience
Thus, Wistar rats were given free access to ethanol (20% in drinking water) or tap water for 2-h sessions during three days, ... a significant deficit in recognition memory was observed in both male and female rats. Western Blot analyses resulted in an ... a significant deficit in recognition memory was observed in both male and female rats. Western Blot analyses resulted in an ... Thus, Wistar rats were given free access to ethanol (20% in drinking water) or tap water for 2-h sessions during three days, ...
https://www.frontiersin.org/articles/10.3389/fnbeh.2017.00233/full
*  Long-term treatment of l-3-n-butylphthalide attenuated neurodegenerative changes in aged rats - Semantic Scholar
In the present study, l-NBP (10 and 30 mg/kg) long-term (3-month) treatment of aged rat (21-month-old) significantly improved ... Our results indicated that long-term treatment with l-NBP might prevent age-related neurodegenerative changes by modulation of ... attenuated the neurodegenerative changes in aged rats. l-NBP treatment significantly increased the choline acetyltransferase ... significantly attenuated cerebral hypoperfusion-induced learning dysfunction and brain damage in rats. ...
https://www.semanticscholar.org/paper/Long-term-treatment-of-l-3-n-butylphthalide-changes-Ma-Xu/25e92d09e39d25554bb9309aa4d1af04e3ca6d40
*  1998 Annual Report | Developmental Effects of Dietary Soy Phytoestrogens | Research Project Database | Grantee Research...
Rats, Long-Evans; Sex Differentiation; Sex Maturation., RFA, Health, Scientific Discipline, Environmental Chemistry, Health ... in Long-Evans hooded rats. We hypothesize that gestational and neonatal exposure to levels of dietary soy phytoestrogens in the ... initial cyclicity in Long-Evans hooded rats. On PND 1, litter size, sex, birth anogenital distance (bAGD), and birth body ... Fifteen adult dams and four adult sires of the Long-Evans hooded strain were purchased from Harlan-Sprague Dawley (Indianapolis ...
https://cfpub.epa.gov/ncer_abstracts/index.cfm/fuseaction/display.highlight/abstract/140/report/1998
*  Studies on Long-Term Depression in Area CA1 of the Anesthetized and Freely Moving Rat | Journal of Neuroscience
Male Long-Evans rats, 3 months of age at the time of surgery, were used. The animals were housed individually and kept in a 12: ... synapses was tested for in a group of 8 freely moving Long-Evans rats implanted bilaterally with stimulating electrodes in the ... whereas the present experiments were performed in Long-Evans rats. Thus, it is unlikely that strain differences account for the ... Studies on Long-Term Depression in Area CA1 of the Anesthetized and Freely Moving Rat. Ursula Staubli and Joey Scafidi ...
http://www.jneurosci.org/content/17/12/4820
*  The Small G Protein H-Ras in the Mesolimbic System Is a Molecular Gateway to Alcohol-Seeking and Excessive Drinking Behaviors |...
Male Long-Evans rats (Harlan; 400-450 g at the time of surgery, 4-5 months old) and male C57BL/6J mice (The Jackson Laboratory ... 2008) Intermittent access to 20% ethanol induces high ethanol consumption in Long-Evans and Wistar rats. Alcohol Clin Exp Res ... Rat operant self-administration experiments were conducted in a within-subject design, whereas rat two-bottle choice and mouse ... C, The NAc of rats lever pressing for 20% alcohol and control rats that were never exposed to alcohol were collected at the end ...
http://www.jneurosci.org/content/32/45/15849.full
*  A comparison of economic demand and conditioned-cued reinstatement of methamphetamine-seeking or food-seeking in rats.
Male Long-Evans rats were lever pressed under increasing fixed-ratio requirements for either food pellets or methamphetamine ( ... Male Long-Evans rats were lever pres ... Rats. Rats, Long-Evans. Recurrence. Reinforcement Schedule. ... In some rats, methamphetamine demand also became less elastic. Continued access to food had no effect on food demand. ...
http://www.biomedsearch.com/nih/comparison-economic-demand-conditioned-cued/21597363.html