Mechanical transduction of nitric oxide synthesis in the beating heart.
Rats. Rats, Inbred WKY. Stress, Mechanical. Grant Support. ID/Acronym/Agency: HL-55397/HL/NHLBI NIH HHS ... lower in the rat heart). In the present study, we demonstrate for the first time that increasing or decreasing ventricular ...http://www.biomedsearch.com/nih/Mechanical-transduction-nitric-oxide-synthesis/9285639.html
Monitoring of intragraft pressure of rejecting organs: increased tissue pressure can be reduced by hyaluronidase therapy.
Rats. Rats, Inbred WKY. Chemical. Reg. No./Substance: 9004-61-9/Hyaluronic Acid; EC 220.127.116.11/Hyaluronoglucosaminidase ... METHODS: At day 5 after syngeneic or allogeneic rat heterotopic heart transplantation, the interstitial pressure of the cardiac ... 18496148 - Red wine polyphenols improve endothelium-dependent dilation in rat cerebral arterioles.. ...http://www.biomedsearch.com/nih/Monitoring-intragraft-pressure-rejecting-organs/11152218.html
Effects of hyperbaric oxygenation on blood pressure levels of spontaneously hypertensive rats.
WKY) and spontaneously hypertensive rats (SHR) were subjected to hyperbaric oxygenation with an enhanced atmospheric pressure ( ... Rats. Rats, Inbred SHR. Rats, Inbred WKY. Comments/Corrections. Erratum In: Clin Exp Hypertens. 2010;32(5):318. ... Five-week-old normotensive Wistar-Kyoto rats (WKY) and spontaneously hypertensive rats (SHR) were subjected to hyperbaric ... There were no differences in BAPs between the normobaric and hyperbaric groups of WKY. In contrast, the hyperbaric group of SHR ...http://www.biomedsearch.com/nih/Effects-hyperbaric-oxygenation-blood-pressure/20504127.html
Upregulation of junctional adhesion molecule-A is a putative prognostic marker of hypertension.
We assess dynamics of junctional adhesion molecule-A (JAM-A) expression in rat models of hypertension and test wh ... Rats. Rats, Inbred SHR. Rats, Inbred WKY. Receptors, Cell Surface / genetics, metabolism*. Time Factors. Up-Regulation. ... We assess dynamics of junctional adhesion molecule-A (JAM-A) expression in rat models of hypertension and test whether JAM-A ... In Goldblatt 2K-1C hypertensive rats, JAM-A expression was augmented before any increase in blood pressure, and similarly JAM-A ...http://www.biomedsearch.com/nih/Upregulation-junctional-adhesion-molecule-putative/22918977.html
Basal plasma corticosterone levels of SHR and WKY males | Open-i
Basal plasma corticosterone levels of SHR and WKY males (M) and females (F), maternally separated (MS) or non-maternally ... In the present study we used an inbred animal model of ADHD, the spontaneously hypertensive rat (SHR), to investigate the long- ... Methods: We applied a rodent model of early life trauma, maternal separation, to SHR and Wistar-Kyoto rats (WKY), the ... Methods: We applied a rodent model of early life trauma, maternal separation, to SHR and Wistar-Kyoto rats (WKY), the ...https://openi.nlm.nih.gov/detailedresult.php?img=PMC3104368_1744-9081-7-11-3&req=4
"The proteasome inhibitor VELCADE reduces infarction in rat models of f" by Nils Henninger, Kenneth M. Sicard et al.
For time-window assessment, male Wistar-Kyoto rats were treated with 0.2 mg/kg VELCADE at 1, 2, or 3 h after the induction of ... male Sprague-Dawley rats received 0.2 mg/kg VELCADE after embolic MCAO (experiment 2). Infarct volume was calculated based on ... VELCADE treatment inhibited whole blood proteasome activity and achieved significant neuroprotection in two rat models of focal ... Rats; Rats, Inbred WKY; Rats, Sprague-Dawley ... For time-window assessment, male Wistar-Kyoto rats were treated ...https://escholarship.umassmed.edu/neuro_pp/169/
Response of AA-resistant Wistar Kyoto (WKY) rats to Bh | Open-i
... rats to Bhsp65 peptides after injection of M. tuberculosis. Rats were immunized with M. tuberculosis subcutaneousl ... In WKY rats, vigorous responses to the BCTD, to which the Lewis rat responded only in the late phase of AA, were observed very ... 1 A), WKY rats could raise significant T cell responses to the BCTD; Lewis rats raised T cell responses to the BCTD only in the ... 1 A), WKY rats could raise significant T cell responses to the BCTD; Lewis rats raised T cell responses to the BCTD only in the ...https://openi.nlm.nih.gov/detailedresult.php?img=PMC2196249_JEM.moudgil3&req=4
Frontiers | Enhanced Eyeblink Conditioning in Behaviorally Inhibited Individuals is Disrupted by Proactive Interference...
... inbred rat strain. WKY rats are a BI strain that has been suggested to be a model of stress and anxiety vulnerability. WKYs ... Paré, W. P. (1989). Stress ulcer susceptibility and depression in Wistar Kyoto (wky) rats. Physiol. Behav. 46, 993-998. doi: ... Paré, W. P. (1994). Open field, learned helplessness, conditioned defensive burying and forced-swim tests in wky rats. Physiol ... Another possible explanation is that WKY rats exhibit learned helplessness to US alone pre-exposures. A significant difference ...https://www.frontiersin.org/articles/10.3389/fnbeh.2016.00039/full
Spontaneous differentiation of PBMC CD8αα+CD3− cell | Open-i
Bottom Line: Isolated PBMC CD8αα+CD3- cells of Lewis rats were transferred into GN-prone Wistar-Kyoto rats at early ... Bottom Line: Isolated PBMC CD8αα+CD3- cells of Lewis rats were transferred into GN-prone Wistar-Kyoto rats at early ... Isolated PBMC CD8αα+CD3- cells of Lewis rats were transferred into GN-prone Wistar-Kyoto rats at early inflammatory stage (days ... Isolated PBMC CD8αα+CD3- cells of Lewis rats were transferred into GN-prone Wistar-Kyoto rats at early inflammatory stage (days ...https://openi.nlm.nih.gov/detailedresult.php?img=PMC4008668_nihms534088f3&req=4
Reducing pup litter size alters early postnatal calcium homeostasis and programs adverse adult cardiovascular and bone health...
Rats, Inbred WKY (MeSH) * Research Design (MeSH) published in * Nutrients Journal Research. keywords * AMNIOTIC-FLUID ... litter size alters early postnatal calcium homeostasis and programs adverse adult cardiovascular and bone health in male rats ...https://scholars.latrobe.edu.au/display/publication346223
Prolonged wakefulness alters neuronal responsiveness to local electrical stimulation of the neocortex in awake rats.. - Surrey...
Rats, Inbred WKY, Sleep, Sleep Deprivation, Time Factors, Wakefulness ... We recently found that sleep deprivation affects spontaneous neuronal activity in the neocortex of sleeping and awake rats. ... Prolonged wakefulness alters neuronal responsiveness to local electrical stimulation of the neocortex in awake rats.. ... Animals, Electric Stimulation, Electroencephalography, Evoked Potentials, Frontal Lobe, Male, Neocortex, Neurons, Rats, ...http://epubs.surrey.ac.uk/825215/
Austin Health Research Online: Impaired arterial baroreceptor reflex and cardiopulmonary vagal reflex in conscious...
Rats. en. dc.subject.other. Rats, Inbred SHR. en. dc.subject.other. Rats, Inbred WKY. en. ... Phenyldiguanide elicited dose-dependent bradycardic and hypotensive responses in WKY rats, but these were significantly ... had a reduced range and lower heart rate plateau in SHR than in WKY rats, which suggests impaired vagal control of the heart ... WKY) rats. The baroreceptor heart rate reflex, elicited by phenylephrine- and nitroprusside-induced changes in blood pressure, ...http://ahro.austin.org.au/austinjspui/handle/1/11265?mode=full
Austin Health Research Online: Advanced glycation end products cause epithelial-myofibroblast transdifferentiation via the...
Rats. Rats, Inbred WKY. Rats, Sprague-Dawley. Receptors, Immunologic.physiology. Transforming Growth Factor beta.analysis. ... Here we report specific binding of (125)I-AGE-BSA to cell membranes prepared from a rat proximal tubule cell line and show that ... Transdifferentiation was also apparent in the proximal tubules of diabetic rats and in a renal biopsy from a patient with type ... The AGE cross-link breaker, phenyl-4,5-dimethylthiazolium bromide (ALT 711) reduced transdifferentiation in diabetic rats in ...http://ahro.austin.org.au/austinjspui/handle/1/9370
Diverse Sensitivity of RHA/Verh and RLA/Verh Rats to Emotional and Spatial Aspects of a Novel Environment as a Result of a...
... avoidance rats constitute a well-recognized model of diverse emotional reactivity. The two Swiss lines display marked... ... Behavioral and neuroendocrine reactivity to stress in the WKHA/WKY inbred rat strains: a multifactorial and genetic analysis. ... Ramos A, Berton O, Mormède P, Chaouloff F (1997) A multiple-test study of anxiety-related behaviors in six inbred rat strains. ... Escorihuela RM, Fernández-Teruel A, Gil L, Aguilar R, Tobeña A, Driscoll P (1999) Inbred Roman high- and low-avoidance rats: ...https://link.springer.com/article/10.1007%2Fs10519-008-9234-z
rian.ie - Results
... inbred rat strain exhibits a stress-hyperresponsive and depressive- and anxiety-like phenotype. Additionally, WKY rats display ... Therefore the WKY rat represents a useful model with which to study the impact of genetic background and negative affect on ... Development and characterisation of a novel, anatomically relevant rat model of acute postoperative pain (2014) ... Development and characterisation of a novel, anatomically relevant rat model of acute postoperative pain (2014) ...http://rian.ie/en/search/results/q/k+all%3Ahigh%3BL%3A7775%2C25%3B
15-Deoxyspergualin potentiates the immunosuppressive effect of cyclosporine A in a rat heart allograft model
Rats, Rats, Inbred Strains, Rats, Inbred WKY, Transplantation, Heterotopic, Transplantation, Homologous National Category Basic ... 15-Deoxyspergualin potentiates the immunosuppressive effect of cyclosporine A in a rat heart allograft model. Gannedahl, G. ...http://umu.diva-portal.org/smash/record.jsf?pid=diva2:865883
Histogram distributions of impulsive, inattentive and h | Open-i
... inattentive and hyperactive behavior in 16 Spontaneously Hypertensive Rats (SHR) and 15 control Wistar-Kyoto (WKY) rats. ... dispersion in hyperactivity outside this interval was also significantly higher in SHR rats than in WKY rats. Some studies ... dispersion in hyperactivity outside this interval was also significantly higher in SHR rats than in WKY rats. Some studies ... SHR/NCrl rats had higher PDi than WKY/Nico controls for impulsiveness and inattention. There was a significant upward trend for ...https://openi.nlm.nih.gov/detailedresult.php?img=PMC2959001_1744-9081-6-56-1&req=4
Changes in renal WT-1 expression preceding hypertension development | BMC Nephrology | Full Text
Weekly, 5 rats per group were sacrificed with a lethal injection of pentobarbital, and their kidneys were removed, decapsulated ... Male spontaneously hypertensive and control rats were evaluated weekly from birth until week 8 of life. Their blood pressure ... Finally, SHRs were originally inbred from Wistar rats and their Wistar-Kyoto (WKY) inbred non-hypertensive controls. These rats ... newborn rat; 2 W: 2-week-old rat; 4 W: 4-week-old rat; 6 W: 6-week-old rat; and 8 W: 8-week-old rat. Magnification: 400X. b ...https://bmcnephrol.biomedcentral.com/articles/10.1186/s12882-016-0250-6
Effects of extract from Clerodendron trichotomum on blood pressure and renal function in rats and dogs.
To assess the action of the herb on blood pressure and renal function, the extract was administered to rats and dogs. ... Rats. Rats, Inbred SHR. Rats, Inbred WKY. Rats, Sprague-Dawley. Renal Circulation / drug effects. Species Specificity. Vascular ... To assess the action of the herb on blood pressure and renal function, the extract was administered to rats and dogs. ... 6205137 - Effects of l-tryptophan on blood pressure in normotensive and hypertensive rats.. 14654157 - Threshold estimates and ...http://www.biomedsearch.com/nih/Effects-extract-from-Clerodendron-trichotomum/8072307.html
Effects of antiserum against alpha-rat atrial natriuretic polypeptide in spontaneously hypertensive rats.
... we investigated the effects of specific rabbit antiserum against alpha-rat ANP (alpha-rANP) on hemodynamics, diuresis, and ... Rats. Rats, Inbred SHR / physiology*. Rats, Inbred Strains / physiology*. Rats, Inbred WKY / physiology. Sodium / urine. Stroke ... and natriuresis in spontaneously hypertensive rats (SHR) and Wistar-Kyoto rats (WKY). Intravenous administration of anti-alpha- ... rANP antiserum caused an obvious rise of mean blood pressure and cardiac output in both SHR and WKY compared with rats ...http://www.biomedsearch.com/nih/Effects-antiserum-against-alpha-rat/2529780.html
Inhibition of p38 mitogen-activated protein kinase is effective in the treatment of experimental crescentic glomerulonephritis...
The treated rats remained healthy with normal weight gain during the study. Both early and late treatment with p38 MAPK ... after induction of nephrotoxic nephritis in Wistar Kyoto rats. ... Rats, Rats, Inbred WKY, p38 Mitogen-Activated Protein Kinases ... after induction of nephrotoxic nephritis in Wistar Kyoto rats. The treated rats remained healthy with normal weight gain during ...https://www.kennedy.ox.ac.uk/publications/217274
Constitutive HIF-1α expression blunts the beneficial effects of cardiosphere-derived cell therapy in the heart by altering...
Rats, Inbred WKY. *Spheroids, Cellular. *Stroke Volume. *Time Factors. *Transfection. *Vascular Endothelial Growth Factor A/ ... Two million male rat CDCs were injected into the infarct following ligation of the mid-LAD in female syngeneic rats. Left ...https://www.ncbi.nlm.nih.gov/pubmed/21538185
Lempel-Ziv complexity of cortical activity during sleep and waking in rats. - Physiology, Anatomy and Genetics
Here, we used extensive data sets obtained in spontaneously awake and sleeping adult male laboratory rats, as well as during ... Rats, Rats, Inbred WKY, Sleep Deprivation, Sleep Stages, Wakefulness ... Here, we used extensive data sets obtained in spontaneously awake and sleeping adult male laboratory rats, as well as during ... Lempel-Ziv complexity of cortical activity during sleep and waking in rats. ...https://www.dpag.ox.ac.uk/publications/508534
Expression of Constitutively Active Angiotensin Receptors in the Rostral Ventrolateral Medulla Increases Blood Pressure |...
rats, inbred WKY. *blood pressure. Neurons of the rostral ventrolateral medulla (RVLM) play a critical role in the generation ... Male Wistar Kyoto (WKY) rats (280 to 300 g), obtained from the Animal Resource Centre (Canning Vale, West Australia, Australia ... Bilateral microinjections of adenoviruses were made into the RVLM of 18 male WKY rats, which had been previously implanted with ... rats (2-way ANOVA followed by Tukey post hoc test used for pairwise comparison). Data are shown only for those rats in which ...http://hyper.ahajournals.org/content/47/6/1054
Myocardial cell growth and blood pressure development in neonatal spontaneously hypertensive rats.
Rats, Rats, Inbred SHR, Rats, Inbred WKY ... normotensive strain Wistar Kyoto rats (WKY) and compared these ... Myocardial cell growth and blood pressure development in neonatal spontaneously hypertensive rats. Academic Article ... Femoral artery blood pressures were obtained from rats at 2 to 5-day intervals from birth to 21 days of age by using a ... Heart weight relative to body weight remained greater in SHR when compared to WKY throughout the 28-day study period, but cell ...http://scholars.uab.edu/display/pub1150031