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*  Orotic acid, nucleotide-pool imbalance, and liver-tumor promotion: a possible mechanism for the mitoinhibitory effects of...
This study was designed to determine the possible mechanism by which orotic acid exerts its mitoinhibitory effect on rat ... Rats. Rats, Inbred F344. Ribonucleoside Diphosphate Reductase / antagonists & inhibitors. Transforming Growth Factor alpha / ... This study was designed to determine the possible mechanism by which orotic acid exerts its mitoinhibitory effect on rat ... or plasma from rats exposed to various liver cell-proliferative stimuli, such as two-thirds partial hepatectomy, lead nitrate, ...
http://www.biomedsearch.com/nih/Orotic-acid-nucleotide-pool-imbalance/1531940.html
*  Fat depot origin affects fatty acid handling in cultured rat and human preadipocytes.
As cultured rat preadipocytes became differentiated, FFA transfer into preadipocytes increased and was more rapid in single pe ... Rats. Rats, Inbred F344. Stem Cells / metabolism*. Substrate Specificity. Tumor Suppressor Proteins*. ... As cultured rat preadipocytes became differentiated, FFA transfer into preadipocytes increased and was more rapid in single ... 3507236 - The effect of storage on rat tissues and human plasma amino acid levels determined by h.... 6295766 - The acute ...
http://www.biomedsearch.com/nih/Fat-depot-origin-affects-fatty/11158926.html
*  Interleukin 15 offers selective protection from irinotecan-induced intestinal toxicity in a preclinical animal model.
Rats. Rats, Inbred F344. Grant Support. ID/Acronym/Agency: CA16056/CA/NCI NIH HHS; R01 CA65761/CA/NCI NIH HHS ... in the modulation of the therapeutic selectivity of CPT-11 in normal rats and rats bearing advanced colorectal cancer. The ... A rat model with dose-limiting toxicity profiles that are similar to those observed in patients treated with CPT-11 was ... Morphological examination of rat intestinal tissues after treatment with LD of CPT-11 revealed dramatic protection of duodenal ...
http://www.biomedsearch.com/nih/Interleukin-15-offers-selective-protection/9699654.html
*  Neurotransmitter alterations associated with feeding and satiety.
Chronically malnourished rats were sacrificed in a food-deprived state, following eating a small amount of food, or following ... Rats. Rats, Inbred F344. Satiation / physiology*. Satiety Response / physiology*. Serotonin / metabolism*. Grant Support. ... Chronically malnourished rats were sacrificed in a food-deprived state, following eating a small amount of food, or following ... 18377969 - Feeding specific glutamate surge in the rat lateral hypothalamus revealed by low-flow p.... 17276349 - Fly foie gras ...
http://www.biomedsearch.com/nih/Neurotransmitter-alterations-associated-with-feeding/3620959.html
*  Acute heat treatment improves insulin-stimulated glucose uptake in aged skeletal muscle.
Rats. Rats, Inbred F344. Grant Support. ID/Acronym/Agency: AG-031575/AG/NIA NIH HHS; HD-002528/HD/NICHD NIH HHS; P20 RR-016475/ ... In the present study, one bout of in vivo heat treatment applied to 24-mo-old Fischer 344 rats improved insulin-stimulated ...
http://www.biomedsearch.com/nih/Acute-heat-treatment-improves-insulin/21148343.html
*  The Ly-49D receptor activates lysis of H-2d-expressin | Open-i
Rats. *Rats, Inbred F344. *Receptors, NK Cell Lectin-Like. *Recombinant Proteins/immunology ... Bottom Line: To define Ly-49D-ligand interactions, we transfected the mouse Ly-49D receptor into the rat NK line, RNK-16 (RNK. ... Bottom Line: To define Ly-49D-ligand interactions, we transfected the mouse Ly-49D receptor into the rat NK line, RNK-16 (RNK. ... To define Ly-49D-ligand interactions, we transfected the mouse Ly-49D receptor into the rat NK line, RNK-16 (RNK.mLy-49D). As ...
https://openi.nlm.nih.gov/detailedresult.php?img=PMC2192910_JEM981115.f3&req=4
*  Quantification of numbers of regenerating BDA+ axons in | Open-i
Mentions: Transplantation of GDAs into stab-wound lesions of the dorsal column white matter pathways of adult rat spinal cord ( ... Mentions: Transplantation of GDAs into stab-wound lesions of the dorsal column white matter pathways of adult rat spinal cord ( ... Grid-walk analysis of GDA-transplanted rats with rubrospinal tract injuries revealed significant improvements in locomotor ... Grid-walk analysis of GDA-transplanted rats with rubrospinal tract injuries revealed significant improvements in locomotor ...
https://openi.nlm.nih.gov/detailedresult.php?img=PMC1561531_jbiol35-2&req=4
*  A) Fluorescence micrograph of the liver including HCC | Open-i
5-Aminolaevulinic acid was intravenously injected to male Fisher rats with HCC at a dose of 500 mg x kg(-1), and the ... 5-Aminolaevulinic acid was intravenously injected to male Fisher rats with HCC at a dose of 500 mg x kg(-1), and the ...
https://openi.nlm.nih.gov/detailedresult.php?img=PMC2376916_89-6601135f6&req=4
*  Semi-quantitative studies of 6-NO2Trp-containing protei | Open-i
Proteomic analysis of endogenous nitrotryptophan-containing proteins in rat hippocampus and cerebellum. ... Proteomic analysis of endogenous nitrotryptophan-containing proteins in rat hippocampus and cerebellum. ... containing proteins are produced in the hippocampus and cerebellum of the adult rat under physiological conditions in vivo. ... containing proteins are produced in the hippocampus and cerebellum of the adult rat under physiological conditions in vivo. ...
https://openi.nlm.nih.gov/detailedresult.php?img=PMC3475453_bsr341i004&req=4
*  Steady-state distribution of endogenous GPI-anchored pr | Open-i
Rats, Inbred F344. *Recombinant Fusion Proteins/metabolism. *Transfection. *Viral Envelope Proteins/metabolism ... Fischer rat thyroid (FRT) cells constitute an ideal model to test this hypothesis, since they missort both endogenous and ... Fischer rat thyroid (FRT) cells constitute an ideal model to test this hypothesis, since they missort both endogenous and ...
https://openi.nlm.nih.gov/detailedresult.php?img=PMC2140173_JCB14620.f7&req=4
*  Antiproliferative activity of casodex (ICI 176.334) in hormone-dependent tumours - Publikationsserver der Universität...
Rats, Inbred F344. MESH. Receptors, Androgen/metabolism. MESH. Testosterone/antagonists & inhibitors. MESH. ... In rats bearing Dunning R3327-G prostate carcinomas casodex exerted a strong antitumour effect at the beginning of therapy. ... Analysis of endocrine effects in rats after 15 days of treatment revealed a strong reduction of the weights of prostates and ... Analysis of endocrine effects in rats after 15 days of treatment revealed a strong reduction of the weights of prostates and ...
https://epub.uni-regensburg.de/4758/
*  The development of HCC in rats exposed to DENA+RS and k | Open-i
The development of HCC in rats exposed to DENA+RS and killed after one year. Panel A: macroscopic appearance, with withish-grey ... Rats were exposed to a protocol for the induction of hepatocellular carcinoma (HCC). Using an orthotopic and syngeneic system ... Rats were exposed to a protocol for the induction of hepatocellular carcinoma (HCC). Using an orthotopic and syngeneic system ... Figure 1: The development of HCC in rats exposed to DENA+RS and killed after one year. Panel A: macroscopic appearance, with ...
https://openi.nlm.nih.gov/detailedresult.php?img=PMC3927807_aging-06-026-g001&req=4
*  Generation of the conditional SIRT1 transgenic mice tha | Open-i
Mice, Inbred C57BL. *Models, Biological. *Rats. *Rats, Inbred F344. *Sirtuin 1. *beta Catenin/metabolism ... We observed that rats on a CR diet have ∼2-fold higher levels of SIRT1 in the gut epithelium relative to ad lib-fed controls ( ... We observed that rats on a CR diet have ∼2-fold higher levels of SIRT1 in the gut epithelium relative to ad lib-fed controls ( ... rats. β-actin served as the loading control in all lanes. (B) Schematic representation of the strategy used for the generation ...
https://openi.nlm.nih.gov/detailedresult.php?img=PMC2289879_pone.0002020.g001&req=4
*  Stage-specific functions of the small Rho GTPases Cdc42 and Rac1 for adult hippocampal neurogenesis - Danish National Research...
Rats; Rats, Inbred F344; cdc42 GTP-Binding Protein; rac1 GTP-Binding Protein Main Research Area: Medical science Publication ...
http://www.forskningsdatabasen.dk/catalog/235074113
*  CTSL1 | Cancer Genetics Web
Rats, Inbred F344. *Enzyme Activation. *Ovarian Cancer. *Mice, Transgenic. *Intracellular Signaling Peptides and Proteins ...
http://cancer-genetics.org/CTSL1.htm
*  Zarbl, H.<...
Sunil, V. R., Vayas, K. N., Fang, M., Zarbl, H., Massa, C., Gow, A., Cervelli, J. A., Kipen, H., Laumbach, R., Lioy, P. J., Laskin, J. & Laskin, D., Feb 1 2017, In : Experimental and Molecular Pathology. 102, 1, p. 50-58 9 p.. Rutgers, The State University. Research output: Contribution to journal › Article ...
https://www.researchwithnj.com/en/persons/helmut-zarbl
*  OPUS at UTS: Intrapleural polymeric films containing cisplatin for malignant pleural mesothelioma in a rat tumour model: a...
Rats, Inbred F344. en_US. dc.subject.mesh. Xenograft Model Antitumor Assays. en_US. ... Methods: An orthotopic rat recurrence model of malignant pleural mesothelioma was used. Five animals per group were evaluated. ... Methods: An orthotopic rat recurrence model of malignant pleural mesothelioma was used. Five animals per group were evaluated. ... Mesothelioma cells were injected subpleurally in the anaesthetised rats. Six days later, a pleural tumour of 5.5 mm was ...
https://opus.lib.uts.edu.au/handle/10453/23525
*  成果報告
Slc:Wistar Outbred Rats Show Close Genetic Similarity with F344 Inbred Rats.. Exp Anim. 2015 Feb 5;64(1):25-9. ... Efficient collection and cryopreservation of embryos in F344 strain inbred rats.. Cryobiology. 2013 Aug 5. [Epub ahead of print ... NBRP-Rat: The worldwide rat resource center. The XVIIIth International Workshop on Genetic Systems in the Rat(京都市)2010.11.30- ... Stress-reactive rats (high-avoidance female rats) have a shorter lifespan than stress-nonreactive rats (low-avoidance female ...
http://www.anim.med.kyoto-u.ac.jp/nbr/publications_jp.aspx
*  Steven Lindley | Stanford Medicine Profiles
Differences in the behavioral responses of Lewis and Fischer (F344) inbred rat strains to stress and psychoactive drugs have ... Together these findings suggest that the inbred, behaviorally divergent F344 and Lewis rats have selective differences in ... corticosterone levels on multiple dopamine neurochemical estimates were examined in inbred Fischer and Lewis inbred rat strains ... In unstressed control animals, the Lewis strain had lower DA concentrations in the dorsal striatum (ST; 80.3% of F344) and ...
https://med.stanford.edu/profiles/steven-lindley
*  a), (b), and (c)) Neural electrophysiology of group A | Open-i
Rats. *Rats, Inbred F344. *Rats, Sprague-Dawley. *Tissue Engineering. Related in: MedlinePlus ... Rats in group A were repaired by acellular nerve grafts only. Rats in group B were repaired by tissue engineering nerve. In ... Rats in group A were repaired by acellular nerve grafts only. Rats in group B were repaired by tissue engineering nerve. In ... Bottom Line: To investigate the effect of tissue engineering nerve on repair of rat sciatic nerve defect.After six and twelve ...
https://openi.nlm.nih.gov/detailedresult.php?img=PMC4120921_NP2014-139085.003&req=4
*  Table of Contents | Disease Models & Mechanisms
Editors' choice: Transferring a Tp53-knockout allele from an outbred rat stock to the F344 inbred rat genetic background alters ... Summary: Feeding with a cafeteria diet (CAF) is a reproducible model of human metabolic syndrome in the rat. By using inbred ... Identification of a nutrient-sensing transcriptional network in monocytes by using inbred rat models on a cafeteria diet Neus ... A rat model for hepatitis E virus Yannick Debing, Niraj Mishra, Erik Verbeken, Kaat Ramaekers, Kai Dallmeier, Johan Neyts ...
http://dmm.biologists.org/content/9/10
*  Changes in male rat urinary protein profile during puberty: a pilot study | BMC Research Notes | Full Text
Earliest patterns comprised rat urinary protein 1, already evident in Sprague-Dawley and Wistar strains at 36 and 52 days, ... By 44 and 57 days major rat protein (α2u-globulin) occurred as the progressively more dominant protein, though as two forms ... Crystal structure of the first-characterised lipocalin of male rats, α2u-globulin, has been determined and peptide sequences ... No significant change in urinary testosterone had occurred in Wistars when major rat protein became evident, but testosterone ...
https://0-bmcresnotes-biomedcentral-com.brum.beds.ac.uk/articles/10.1186/1756-0500-6-232
*  Repeated fear-induced diurnal rhythm disruptions predict PTSD-like sensitized physiological acute stress responses in F344 rats...
Rats, Inbred F344. *Stress Disorders, Post-Traumatic/physiopathology*. *Stress, Physiological/physiology*. *Stress, ... Adult male F344 rats implanted with biotelemetry devices were exposed to repeated conditioned fear or control conditions for 22 ... Repeated fear-induced diurnal rhythm disruptions predict PTSD-like sensitized physiological acute stress responses in F344 rats ... Rats exposed to repeated fear had fear-evoked increases in behavioural freezing and HR/CBT during exposure to the fear ...
https://www.ncbi.nlm.nih.gov/pubmed/24447583?access_num=24447583&link_type=MED&dopt=Abstract
*  Strain differences influence timing and magnitude of both acute and late inflammatory reactions after intratracheal...
The DA rat strain was used to establish a lung exposure model. Five other inbred rat strains (PVG, PVG.1AV1, LEW, WF and F344) ... All rat strains displayed a biphasic pattern of leukocyte infiltration in the lungs, dominated by neutrophils 2 days after ... The number of macrophages was higher in the DA rat compared with the other strains. The infiltration of lymphocytes in the ... With a novel focus on the immune system this paper investigate whether late phase pulmonary effects developed in rats exposed ...
http://onlinelibrary.wiley.com/doi/10.1002/jat.2878/abstract?globalMessage=0
*  Prednisolone has a positive effect on the kidney but not on the liver of brain dead rats: a potencial role in complement...
Our study aimed to evaluate this disparity by investigating the effect of prednisolone administration on BD rats. METHODS: BD ... mechanisms in the liver may explain the disparity between the effects of prednisolone on the kidney and liver of BD rats. The ... induction was performed in ventilated rats by inflating a Fogarty catheter placed in the epidural space. Prednisolone (22.5 mg/ ... Rats, Inbred F344, Real-Time Polymerase Chain Reaction ... METHODS: BD induction was performed in ventilated rats by ...
https://www.situ.ox.ac.uk/publications/466758