Effect of muscle length on cross-bridge kinetics in intact cardiac trabeculae at body temperature.
Rats. Rats, Inbred BN. Sarcomeres / physiology*. Ventricular Myosins / physiology. Grant Support. ID/Acronym/Agency: R01 ... Intact muscle can be used to assess ktr in rat and rabbit myocardium First, we compared ktr in two species: the rat, which ... than in rat muscle (which contains predominantly α myosin). Analyses of k(tr) in rat muscle at optimal length (L(opt)) and 90% ... we used rats for most experiments. Male brown Norway rats (∼3 mo old and weighing 250 g; n = 11) were anesthetized ...http://www.biomedsearch.com/nih/Effect-muscle-length-cross-bridge/23277479.html
Effect of renin gene transfer on blood pressure in the spontaneously hypertensive rat.
BN) rats, we measured blood pressure in an SHR progenitor strain and an ... whether molecular variation in the renin gene contributes to the greater blood pressure of spontaneously hypertensive rats (SHR ... Rats. Rats, Inbred BN. Rats, Inbred SHR. Renin / biosynthesis*, genetics*. Triglycerides / blood. ... BN) rats, we measured blood pressure in an SHR progenitor strain and an SHR congenic strain that are genetically identical ...http://www.biomedsearch.com/nih/Effect-renin-gene-transfer-blood/9453331.html
JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
The Brown-Norway (BN) inbred rat presents a higher frequency of PDA. A previous study reported that 2 different quantitative ... Nevertheless, the genetic or molecular mechanisms underlying PDA phenotypes in BN rats have not been fully investigated yet. ... Using DA explants from rat fetuses at embryonic day 19 as a ex vivo model and primary cultured rat DA smooth muscle cells from ... We compared the transcriptional profiles of the DA and the aorta of Wistar rat fetuses on embryonic day 19 (preterm) and day 21 ...https://www.jove.com/visualize?author=Susumu%20Minamisawa%20
Chromosomal Mapping of Quantitative Trait Loci Controlling Elastin Content in Rat Aorta | Hypertension
Inbred BN rats were obtained from Iffa Credo (Domaine des Oncins, l'Arbesle, France) and inbred LOU rats were from our own ... The inbred Brown Norway (BN) rat strain shows an aortic elastin deficit (by 5.8% dry weight when compared with the inbred LOU ... Female LOU rats and male BN rats were mated to produce an F1 population. Rats of the F1 generation were mated to produce the ... We previously demonstrated that the inbred Brown Norway (BN) rat shows an aortic elastin deficit in both abdominal and thoracic ...http://hyper.ahajournals.org/content/45/3/460
Inbred BN rats were from Elevage Janvier (Le Genest St Isle, France) and inbred LOU/M rats from our own breeding stock. F1 rats ... Means ± SE of HN scores were calculated in rats homozygous (BN/BN) and heterozygous (BN/LOU) for this marker. Number of rats in ... rat (4, a), a male LOU rat (0, b), a male backcross (BC) rat (2, c), a male BC rat (4, d), and 2 female BC rats with extreme ... Subsequent studies in BN and LOU rats showed that this feature is absent in the LOU but not uncommon in the BN male rat (Table ...http://physiolgenomics.physiology.org/content/34/2/215
RePub, Erasmus University Repository: Improved antitumor response to isolated limb perfusion with tumor necrosis factor after...
Rats, Rats, Inbred BN, Sarcoma/*therapy, Soft Tissue Neoplasms/*therapy, Transfection/methods, Tumor Necrosis Factor-alpha/* ... Results of the TNF perfusions in rats suggest that this tumor is more sensitive to TNF therapy. CONCLUSIONS: EMAP-II is ... In an extremity perfusion model in tumor-bearing rats, we measured response rates to TNF therapy. RESULTS: Functional EMAP-II ... Immunostaining of paraffin-embedded tumor tissue sections in rats showed an overexpression of human EMAP-II. ...https://repub.eur.nl/pub/9996
Megalin-dependent cubilin-mediated endocytosis is a major pathway for the apical uptake of transferrin in polarized epithelia ...
Inbred BN Rats, Kidney, LDL-Receptor Related Protein 2, Transferrin, Yolk Sac, Animals, Dogs, Mice, Rats. ...http://edoc.mdc-berlin.de/5032/
NAVER Academic > Search...
Rats, Inbred BN, Somatostatin, genetics,... ... Melanin-Concentrating Hormone in Human Rat. 1995 Takahashi K et ... Role of insulin-like growth factor I in regulating growth hormone release and feedback in the male rat.. 1995 K Becker et al. ... Growth-hormone-releasing hormone mediates the sleep-promoting activity of interleukin-1 in rats.. 1995 F Jr Obál et al. ... Aging, Animals, Arcuate Nucleus of Hypothalamus, cytology, Cell Count, Female, Immunohistochemistry, Mice, Mice, Inbred C57BL, ...https://academic.naver.com/search.naver?field=3&query=Neuroendocrinology+61%EA%B6%8C+5%ED%98%B8
... from the inbred BN rat was substituted one at a time into the homogeneous background of the inbred SS rat. In this case, BN and ... the aortas of the SS-18BN, SS-XBN, SS-7BN, SS-(D8rat163-D8rat81)BN, SS-13BN, SS-15BN, SS-11BN, SS-10BN, SS-16BN, and SS-6BN ... whereas aortic rings of the SS-11BN, SS-5BN, SS-13BN, SS-3BN, SS-14BN, SS-4BN, SS-15BN, SS-12BN, SS-17BN, and SS-19BN generated ... SS-11BN, SS-18BN, SS-3BN, SS-17BN, SS-15BN, SS-12BN, SS-19BN, and SS-5BN generated significantly less force. Of the rats on a ...http://physiolgenomics.physiology.org/content/26/3/218
MGI-Guidelines for Nomenclature of Mouse and Rat Strains
1.2 Rats. 2. Laboratory codes. 3. Inbred Strains and Hybrids. 3.1 Definition 3.2 Nomenclature of Inbred Strains. 3.3 Indication ... SHR-Chr YBN. In this consomic rat strain, the Y chromosome from BN has been backcrossed onto SHR. ... 4.3 Mixed Inbred Strains. Incipient inbred stocks or inbred strains that are derived from up to three parental strains (one of ... 5.4 Segregating Inbred Strains. Segregating inbred strains are inbred stains in which a particular allele or mutation is ...http://www.informatics.jax.org/mgihome/nomen/strains.shtml
Trophoblast Differentiation - Michael Soares
The BN inbred rat has restricted trophoblast cell invasion and has been used to generate consomic rat strains with the Dahl SS ... inbred rat and BN consomic rat strains. Maternal hypoxia during critical phases of placentation can activate the invasive ... 2 is on investigating mechanisms underlying BN rat trophoblast cell invasion defects. We assert that intrauterine trophoblast ... Dhakal, Pramod; Soares, Michael J (2017) Single-step PCR-based genetic sex determination of rat tissues and cells. ...http://grantome.com/grant/NIH/R01-HD020676-22
Uterine rejection after allogeneic uterus transplantation in the rat is effectively suppressed by tacrolimus. - PubMed - NCBI
Rats, Inbred BN. *Rats, Inbred Lew. *Tacrolimus/pharmacology*. *Transplantation, Homologous. *Uterus/transplantation* ... Female rats.. INTERVENTION(S): Uteri from brown Norway rats were transplanted to Lewis rats, receiving either tacrolimus or no ... Uterine rejection after allogeneic uterus transplantation in the rat is effectively suppressed by tacrolimus.. Akhi SN1, Diaz- ...https://www.ncbi.nlm.nih.gov/pubmed/23218920
RBM20, a gene for hereditary cardiomyopathy, regulates titin splicing - MDC Repository
Base Sequence, Dilated Cardiomyopathy, Inbred BN Rats, Inbred F344 Rats, LIM Domain Proteins, Molecular Sequence Data, Muscle ... In addition to titin (TTN), we identified a set of 30 genes with conserved splicing regulation between humans and rats. This ... By positional cloning using a previously characterized rat strain with altered titin mRNA splicing, we identified a loss-of- ... The phenotype of Rbm20-deficient rats resembled the pathology seen in individuals with dilated cardiomyopathy caused by RBM20 ...http://edoc.mdc-berlin.de/12300/
Ferroportin and iron export from the macrophage
inbred bn rats*reducing diet*hypertrophic cardiomyopathy*metallothionein*hand strength*hematocrit*autopsy*nerve degeneration* ...https://www.labome.org/grant/k01/dk/ferroportin/and/ferroportin-and-iron-export-from-the-macrophage-7278826.html
Organic Eprints - The effects of organically and conventionally cultivated plant feed on fertility and health in two inbred...
Two inbred rat strains have been selected: the BN/hsdCpb which is characterised by a relatively low fertility and the GK/mol, a ... The effects of organically and conventionally cultivated plant feed on fertility and health in two inbred rat strains ... The effects of organically and conventionally cultivated plant feed on fertility and health in two inbred rat strains. Speech ... In addition, a macroscopical pathological evaluation of all rats at autopsy will be performed, after the reproductional phase ...http://orgprints.org/1587/
Neither the New Zealand Genetically Hypertensive Strain nor Dahl Salt-Sensitive Strain Has an A1079T Transversion in the α1...
23 Genomic DNA from 11 SS/Jr rats, 7 SR/Jr rats, 2 GH rats, 1 BN rat, 1 WKY rat, 1 SHR, 1 DRY rat, and 1 Lewis rat was assayed ... A putative 1079A→T mutation in the α1 isoform of the Na+, K+-ATPase (Atp1a1) gene of the Dahl salt-sensitive rat inbred by John ... 35398, SR/Jr; (6) RAT No. 34582, SR/Jr; (7) RAT No. 63803, SS/Jr; (8) RAT No. 364530, SS/Jr; (9) RAT No. 64578, SS/Jr; (10) BN ... 61644, SS/Jr; (6) RAT No. 62869, SS/Jr; (7) RAT No. 35315, SR/Jr; (8) RAT No. 34581, SR/Jr; (9) RAT No. 63335, SS/Jr; (10) RAT ...http://hyper.ahajournals.org/content/38/4/786
Adolescent Eating Disorders Predict Psychiatric, High-Risk Behaviors and Weight Outcomes in Young Adulthood. - Semantic Scholar
BN: OR = 5.72, 95% CI = 2.22-14.72; PD: OR = 4.88, 95% CI = 2.78-8.57; subthreshold BN: OR = 3.97, 95% CI = 1.44-10.98; and ... AN, BN, BED, PD, and OSFED were prospectively associated with depression (respectively AN: odds ratio [OR] = 1.39, 95% CI = ... 1.00-1.94; BN: OR = 3.39, 95% CI = 1.25-9.20; BED: OR = 2.00, 95% CI = 1.06-3.75; and PD: OR = 2.56, 95% CI = 1.38-4.74). All ... subthreshold BN, and BED at ages 14 and 16 years, are prospectively associated with later depression, anxiety disorders, ...https://www.semanticscholar.org/paper/Adolescent-Eating-Disorders-Predict-Psychiatric%2C-in-Micali-Solmi/f358c171edea781c516ed04d07ef3fdb1f9c470a
Genetic Isolation of a Chromosome 1 Region Affecting Blood Pressure in the Spontaneously Hypertensive Rat | Hypertension
Wistar-Kyoto rats,6 and in a series of recombinant inbred strains derived from SHR×BN-Lx rats.7 ... We measured blood pressure in 9 male congenic SHR.BN-D1Mit3/Igf2 rats and 12 male progenitor SHR rats in two separate studies. ... BN) strain. In male SHR congenic rats carrying the transferred BN chromosome segment, 24-hour average systolic and diastolic ... A genetic linkage map of the rat derived from recombinant inbred strains. Mamm Genome.. 1996;7:117-127. ...http://hyper.ahajournals.org/content/30/4/854
Protocols and Video Articles Authored by Saskia S. Arndt
Cognition and Social Interaction in Mice and Rats' ... In this study four phylogenetically distant inbred rat strains ... For example, the BN did not show recruitment of the basolateral amygdala, whereas the WKY, FH and LE did. During the hot plate ... Nociception and Conditioned Fear in Rats: Strains Matter PloS One. 2013 , Pubmed ID: 24376690 When using rats in pain research ... The rats from the thrice-a-day group suffered from more side-effects, as the growth rate was decreased and more plastic was ...https://www.jove.com/author/Saskia+S._Arndt
Genetic Variation in Renal Expression of Folate Receptor 1 (Folr1) Gene Predisposes Spontaneously Hypertensive Rats to...
In this study, in the BXH/HXB recombinant inbred (RI) strains derived from the SHR strain and the normotensive Brown Norway (BN ... BN-Lx/Cub rats (referred to as the BN strain), BXH/HXB RI strains7 derived from the SHR and BN progenitor strains, SHR.BN- ... D1Mit3/Igf2 congenic rats8 (referred to as the SHR.BN-chr.1 congenic strain), and SHR/Ola-TgN(EF1aFolr1)Ipcv transgenic rats ( ... Transgenic rats, derived by microinjections of SHR ova with the construct containing BN Folr1 cDNA under control of EF-1α ...http://hyper.ahajournals.org/content/67/2/335
List of MeSH codes (B01) - Wikipedia
... rats, inbred aci MeSH B01.050.157.760.090 --- rats, inbred bb MeSH B01.050.157.760.110 --- rats, inbred bn MeSH B01.050.157.760 ... rats, inbred aci MeSH B01.050.199.520.760.090 --- rats, inbred bb MeSH B01.050.199.520.760.110 --- rats, inbred bn MeSH B01.050 ... rats, inbred buf MeSH B01.050.157.760.165 --- rats, inbred dahl MeSH B01.050.157.760.200 --- rats, inbred f344 MeSH B01.050. ... rats, inbred lew MeSH B01.050.157.760.290 --- rats, inbred oletf MeSH B01.050.157.760.300 --- rats, inbred shr MeSH B01.050. ...https://en.wikipedia.org/wiki/List_of_MeSH_codes_(B01)
Characterization of antibody responses induced in rodents by exposure to food proteins: influence of route of exposure. -...
All test proteins were clearly immunogenic when administered by gavage to BN rats, with measurable, and in some cases very ... Furthermore, gavage treatment failed to induce detectable IgE responses in the BN rat, suggesting that the ability these ... none of the proteins provoked detectable IgE antibody following gavage administration to BN rats. In contrast, in BALB/c mice ... rats by daily gavage administration and in BALB/c strain mice following intraperitoneal or gavage exposure to food proteins of ...https://www.semanticscholar.org/paper/Characterization-of-antibody-responses-induced-in-Dearman-Caddick/a6d69e9f6195ee9118b8f2783810cc0c01a57c26
DiVA - Search result
... only in DA rats. Sensitization of the rats induced a prominent OVA-specific-IgE and IgG response in the BN rat while DA rats ... in naïve rats and in rats with induced allergic airway disease. The responses of two different inbred rat strains were compared ... DA rats were found to be higher responder compared to BN rats, both when it comes to responses in naïve and sensitized rats. ... Naïve rats were exposed to an aerosol of TiO2 NPs once daily for 10 days. Another subset of rats was sensitized to the allergen ...http://umu.diva-portal.org/smash/resultList.jsf?af=%5B%5D&aq=%5B%5B%7B%22personId%22%3A%22authority-person%3A63293%22%7D%5D%5D&aqe=%5B%5D&aq2=%5B%5B%5D%5D&language=en&query=
Comparative analysis of methods for gene transcription profiling data derived from different microarray technologies in rat and...
... we used biopsies of male inbred rats of the diabetic Goto-Kakizaki (GK) strain , the normoglycaemic Brown-Norway (BN) and ... WKY-STZ rats also referred as STZ throughout the article). Rats of the GK and BN strains were from the Oxford colony (GK/Ox, BN ... Rat liver transcriptome on Affymetrix), E-TABM-500 (Rat kidney transcriptome on Operon), E-TABM-502 (Rat kidney transcriptome ... The comparison between inbred rat strains for hepatic and renal gene expression, which was repeated on Affymetrix, Illumina and ...http://pubmedcentralcanada.ca/pmcc/articles/PMC2652496/
January | 2015 | Thrombin Inhibitors
We're making use of inbred ACI, COP and BN rats to define the mechanisms via which estrogens contribute to mammary cancer ... Interestingly, tumor development in ACI rats also needs the action of progesterone. By contrast, COP and BN rats are resistant ... have already been mapped in crosses concerning susceptible ACI rats and resistant COP or BN rats. Each with the mapped ... Rat aortic smooth muscle cells have been stimulated with PDGF BB for five min for ERK 12 and PLC1, 15 min for Akt ...http://thrombininhibitors.com/2015/01