Topical Hypericum perforatum Improves Tissue Regeneration in Full-Thickness Excisional Wounds in Diabetic Rat Model
Forty-eight female diabetic rats were randomly divided into four groups (,svg xmlns:xlink=http://www.w3.org/1999/xlink xmlns ... In this experimental study, 48 female Wistar rats (. g; 2-3 months old) kept in standard cages with food and water ad libitum ... Forty-eight female diabetic rats were randomly divided into four groups (. ): gel base treated group, HP 5% gel treated group, ... On day 0, rats were wounded (a 1 cm2 circular full-thickness skin wound) under general anesthesia induced by ether inhalation ...
Increased Clearance of Reactive Aldehydes and Damaged Proteins in Hypertension-Induced Compensated Cardiac Hypertrophy: Impact...
Hypertensive rats presented signs of cardiac oxidative stress, depicted by increased lipid peroxidation. However, these changes ... Sedentary SHR displayed cardiac hypertrophy with preserved ventricular function compared to normotensive rats, characterizing a ... counteract the deleterious effect of excessive oxidative stress in hypertension-induced compensated cardiac hypertrophy in rats ... impact of ET on cardiac protein quality control during compensated ventricular hypertrophy in spontaneously hypertensive rats ( ...
Influence of Chronic Alcohol Use on Osteoblastic Differentiation of Bone Marrow Cells, Bone Properties, and Hepatic and Renal...
Wistar rats were divided into three groups (,span class=inline_break,,svg xmlns:xlink=http://www.w3.org/1999/xlink xmlns= ... The aim of this study was to evaluate the effects of chronic use of 20% alcohol on rats regarding osteoblastic differentiation ... in rats, with similar formation of nodules in all groups (,span class=inline_break,,svg xmlns:xlink=http://www.w3.org/1999/ ... Wistar rats were divided into three groups (. ) in accordance with a 24-week diet. After euthanasia, kidneys, liver, and tibias ...
Prostaglandin Analogous and Antioxidant Activity Mediated Gastroprotective Action of Tabernaemontana divaricata (L.) R. Br....
Adult male Wistar rats weighing 150-200 gm were used for the evaluation of antiulcer activity. The animals were maintained ... stem hydro-alcoholic extract in three gastric-ulceration models of wistar rats," Boletín Latinoamericano y del Caribe de ... on aspirin-induced gastric lesions in Wistar rats," Pharmacologyonline, vol. 1, pp. 279-293, 2008. ... Flower Methanolic Extract against Chemically Induced Gastric Ulcers in Rats. Mohammed Safwan Ali Khan. ,1,2Abdul Manan Mat Jais ...
A Novel Herbal Medicine for Dyslipidemia: Assessments in Experimental Models
HDL cholesterol levels increased in rats with high doses of GANMO compared to those with low doses. GANMO at both doses ... In the exogenous hyperlipidemia model, rats were given oral administration of oil-cholesterol mixture and GANMO for 4 ... In the endogenous hyperlipidemia model, rats were previously treated with GANMO tablets and intraperitoneally injected with ... Wistar Albino rats (180-220 g) were divided into 5 groups with 10 rats per group. Rats were given oral medication twice per day ...
A 90-Day Oral Toxicological Evaluation of the Methylurate Purine Alkaloid Theacrine
Four groups of Hsd.Brl.Han Wistar rats (ten/sex/group) were administered theacrine by gavage doses of 0 (vehicle only), 180, ... J. Vandenberghe, Life-Span Data and Historical Data in Carcinogenicity Testing in Wistar Rats Crl:(WI) BR. Addendum 5.8, ... Male and female SPF Hsd.Brl.Han Wistar rats (Toxi-Coop, Budapest, Hungary) were housed individually, with a 12-hour light-dark ... Four groups of Hsd.Brl.Han Wistar rats (ten/sex/group) were administered theacrine by gavage doses of 0 (vehicle only), 180, ...
Antihyperlipidemic and Antioxidant Potential of Paeonia emodi Royle against High-Fat Diet Induced Oxidative Stress
... in high-fat diet induced hyperlipidemic/oxidative stressed rats. ... Male Wistar rats were induced with hyperlipidemia using high- ... Male Wistar rats (. g) were purchased from the Indian Institute for Integrative Medicine (IIIM), Jammu, India, and they were ... Male Wistar rats were induced with hyperlipidemia using high-fat diet and were treated orally with hydroalcoholic and aqueous ... Male Wistar rats fed with high-fat diet showed a marked elevation in serum triglycerides, total, and LDL cholesterol. ...
Screening of Indigenous Oxalate Degrading Lactic Acid Bacteria from Human Faeces and South Indian Fermented Foods: Assessment...
strains were used to colonize the rat intestine by oral administration. Sixteen male albino Wistar rats with an average body ... The impact of probiotics on rat gut microbiota was evaluated using culture-dependent analysis in faecal samples. Rat faecal ... Analysis of faecal microbiota composition in rats before and after oral administration of selected Lactobacillus. Each rat ... strains from rat faecal samples on days 3, 7, and 14. The data is represented as mean value of log CFU/g faeces. strains were ...
Comparison of the Spasmolytic Effects of Jakyak-Gamcho Decoctions Derived via Different Extractants
... before and 1 and 2 h after injection in rats. ,i,Results,/i,. The relative amounts of effective index components were, on ... Four male Wistar rats aged 7-8 weeks and weighing 172.5-183.1 g were used in a preliminary experiment to determine the ... In the actual experiment, 5 male Wistar rats aged 7-8 weeks and weighing 178.6-195.8 g were used in each group. A distilled ... As each individual rat possesses different muscle force, it is not appropriate to simply compare the muscle cramp-induced ...
Transplantation of Neural Stem Cells Cotreated with Thyroid Hormone and GDNF Gene Induces Neuroprotection in Rats of Chronic...
EAE rats were, respectively, injected with NSCs, T3/NSCs, GDNF-T3/NSCs, and saline at 10 days and sacrificed at 60 days after ... Growth, Induction, and Infection of Rat Neurospheres. The cerebral hemispheres dissected from newborn Wistar rats (Animal House ... EAE is induced in female Wistar rats by guinea pig spinal cord homogenate emulsified with complete Freunds adjuvant (CFA, ... NSCs were isolated from newborn Wistar rats cerebral hemispheres and proliferated into round floating spheres after 5~7 days of ...
A New Model of Diarrhea with Spleen-Kidney Yang Deficiency Syndrome
Rats were randomly divided into 4 groups: the control (C)-, high (H)-, middle (M)-, and low (L)- dose groups. The groups ... for 4 weeks was used to create a rat model of diarrhea with spleen-kidney yang deficiency syndrome. ... i, Objective,/i,. The aim of this study was to examine a new method to create a rat model of diarrhea with spleen-kidney yang ... Twenty-four male Wistar rats (70 ± 10 g) were obtained from the Laboratory Animal Center of the Academy of Military Medical ...
Honey as a Potential Natural Antioxidant Medicine: An Insight into Its Molecular Mechanisms of Action
Administration of honey and Aloe vera solution showed a marked decrease in expression of Ki67-LI in tumor cells in Wistar rats ... to blood pressure and oxidative stress in streptozotocin-induced diabetic wistar-kyoto rats and spontaneously hypertensive rats ... and alanine transaminase against isoproterenol-induced myocardial infarction in Wistar rats [168]. It shows that honey gives ... "Sundarban honey confers protection against isoproterenol-induced myocardial infarction in Wistar rats," BioMed Research ...
AcT-2: A Novel Myotropic and Antimicrobial Type 2 Tryptophyllin from the Skin Secretion of the Central American Red-Eyed Leaf...
... and to contract rat urinary bladder smooth muscle (EC,sub,50,/sub, = 9.3 ,i,μ,/i,M). The peptide could also ... Rat Smooth Muscle Bioassays. Male Wistar rats (250-300 g) were euthanized by carbon dioxide asphyxiation followed by cervical ... In rat tail artery smooth muscle preparations, AcT-2 caused a dose-dependent relaxation with an EC50 of 5.1 nM (Figure 3(a)). ... After removing the fur on the abdomen of rats, the body cavity was opened and any visible fat was removed. The exposed urinary ...
Effects of Angiotensin-Converting Enzyme Inhibitor Derived from Tropaeolum majus L. in Rat Preimplantation Embryos: Evidence...
Pregnant Wistar rats received orally the HETM (3, 30, and 300 mg/kg/day) from the 1st to the 7th gestational day. Rats ... Pregnant Wistar rats received orally the HETM (3, 30, and 300 mg/kg/day) from the 1st to the 7th gestational day. Rats were ... B. Liuti et al., "Evaluation of subchronic toxicity of the hydroethanolic extract of Tropaeolum majus in Wistar rats," Journal ... Wistar rats were obtained from the Federal University of Parana, Brazil, and maintained under controlled conditions at 22 ± 2°C ...
Anatomic Changes in the Macroscopic Morphology and Microarchitecture of Denervated Long Bone Tissue after Spinal Cord Injury in...
The study design was based on two main groups of juvenile male Wistar rats with SCI: one was followed for 33 days with ... Significant reduction of bone mass and periosteal radii was observed in the SCI rats, whereas PS and ES efficiently improved ... The SEM images showed less and thin trabecular bone in SCI rats. PS and ES efficiently ameliorated the bone microarchitecture ... The femur and tibia were assessed macroscopically and microscopically by scanning electronic microscopy (SEM). The SCI rats ...
The Effect of Two Types of Exercise Preconditioning on the Expression of TrkB, TNF-α, and MMP2 Genes in Rats with Stroke
Forty male adult Wistar rats were exposed to aerobic exercises following randomization into four groups, including swimming + ... Forty male adult Wistar rats were exposed to aerobic exercises following randomization into four groups, including swimming + ... This experimental study was performed with 40 male adult Wistar rats breed at the age of eight weeks and an approximate weight ... 23] investigated the effect of running exercise on wheel running users on TrkB values in male Wistar rat hippocampus. The ...
Simvastatin Blocks Blood-Brain Barrier Disruptions Induced by Elevated Cholesterol Both In Vivo and In Vitro
To further test the results in vivo, rat brain microvascular endothelial cells (RBMECs) were stimulated with cholesterol in the ... Primary cultures of rat brain microvessel endothelial cells (RBMECs) were isolated from Wistar rat (approximately 100 g) brains ... Rat primary brain endothelial cells were stimulated for 24 h with 10 μM cholesterol in the presence or absence of simvastatin ( ... In brief, fresh rat brains were obtained, and the surface vessels and meninges of the brains were removed. The grey matter was ...
The Anxiolytic Effects of Valtrate in Rats Involves Changes of Corticosterone Levels
The aim of the present study was to investigate the anxiolytic effects of valtrate in rats. The animals were orally ... Valtrate (10 mg/kg, p.o.) significantly reduced the corticosterone level in the rat serum. Taken together, these results ... exhibited the anxiolytic effect in rats by increasing the time and entry percentage into the open arms in the EPM and the ... Then the corticosterone levels in the rat serum were measured by enzyme-linked immunosorbent assay (ELISA). The valtrate (10&# ...
miR-181a Ameliorates the Progression of Myasthenia Gravis by Regulating TRIM9
"Combinatory effects of bone marrow-derived mesenchymal stem cells and indomethacin on adjuvant-induced arthritis in Wistar rats ... V. A. Lennon, J. M. Lindstrom, and M. E. Seybold, "Experimental autoimmune myasthenia: a model of myasthenia gravis in rats and ... 14], 2.5 mg rat-derived peptide (Shanghai Gill Biochemical Co. Ltd.) was taken by microbalance in the precision instrument room ... α-subunit induces experimental myasthenia gravis in rats," The Journal of Immunology, vol. 172, no. 4, pp. 2697-2703, 2004. ...
Beneficial Effects of Bauhinia rufa Leaves on Oxidative Stress, Prevention, and Treatment of Obesity in High-Fat Diet-Fed C57BL...
"Kaempferol and zinc gluconate mitigate neurobehavioral deficits and oxidative stress induced by noise exposure in Wistar rats ... P. M. Amália, M. N. Possa, M. C. Augusto, and L. S. Francisca, "Quercetin prevents oxidative stress in cirrhotic rats," ... "Adipogenic and lipolytic effects of ascorbic acid in ovariectomized rats," Yonsei medical journal, vol. 59, no. 1, pp. 85-91, ... Skeels leaves and continuous aerobic training in rats with diabetes induced by a high-fat diet and low doses of streptozotocin ...
Decreased Fast Ripples in the Hippocampus of Rats with Spontaneous Recurrent Seizures Treated with Carbenoxolone and Quinine
Male Wistar rats (190-200 g) were housed individually in cages in a temperature-controlled room (. °C), on a 12 h light/dark ... rats each one) and three experimental groups of animals (. each one) with recurrent spontaneous seizures, the latter receiving ... Control rats were anaesthetized as indicated above and they were positioned in a stereotaxic frame such that lambda and the ... In terms of their behavior, the rats that received CBX showed vibrissae movements, and while they remained in a state of sleep ...
Aqueous Root Bark Extract of Daniellia oliveri (Hutch. & Dalz.) (Fabaceae) Protects Neurons against Diazepam-Induced Amnesia in...
... effects of Leea macrophylla methanol root extracts on diazepam-induced memory impairment in amnesic Wistar albino rat," ... J. A. Harris and R. F. Westbrook, "Benzodiazepine-induced amnesia in rats: reinstatement of conditioned performance by noxious ... "Effects of boswellia papyrifera gum extract on learning and memory in mice and rats," Iran Journal of Biomedical Science, vol. ... "Effect of atorvastatin and rosuvastatin on learning and memory in rats with diazepam-induced amnesia," Folia Medical, vol. 55, ...
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Safety Evaluation of Artocarpus altilis as Pharmaceutical Agent in Wistar Rats. List of Authors. *Sudha Sairam ...
Changes in Mitochondria-Related Gene Expression upon Acupuncture at LR3 in the D-Galactosamine-Induced Liver Damage Rat Model
Liver tissues were extracted from experimental and untreated control rats for histopathological analysis and expression ... in experimental rats, who then received either sham (ALF), manual acupuncture (MA), electroacupuncture (EA), or silymarin (PC, ... Pathogen-free male Wistar rats (150-180 g) were purchased from SamTako Bio (Osan, Korea) and housed under controlled ... Twenty-five male Wistar rats were randomly divided into five groups, including four experimental groups (ALF, positive control ...