We recently discovered that the stress granule protein G3BP1 (Ras GTPase-activating protein-binding protein 1) anchors the TSC ... The tuberous sclerosis protein (TSC) complex acts as a relay for anabolic signaling and as a tumor suppressor. These functions ... This seems to be at odds with the requirement of amino acids for protein biosynthesis in rapidly growing tumor cells; raising ... Alexander Martin Heberle: "A stress granule protein integrates metabolic signals and controls lysosomal TSC recruitment and ...

Sequence similarity was found to a putative Ras GTPase activating protein and a human interferon-gamma binding protein both in ... GTPase-activating proteins and nucleotide-exchange factors, including such proteins as Vav, Dbl and Bcr, and there are two PH ... GTPase-activating proteins and nucleotide-exchange factors. Its function is not known, but many proteins that contain a PH ... guanine nucleotide exchange proteins like vav, dbl, SoS and Saccharomyces cerevisiae CDC24, GTPase activating proteins like ...

Protein: P46940 IQGAP1, Ras GTPase-activating-like protein IQGAP1, human. Predictions only. Length 1,657 aa. ... Protein. RNA. Prediction (catRAPID). Interaction (ENCODE eCLIP). Gene UniProt Accession Transcript Symbol Ensembl Transcript ID ... Retrieved 100 of 98,524 protein-RNA pairs in 15.4 ms ...

The intracellular region of plexins is essential for signaling and contains a R-Ras/M-Ras GTPase activating protein (GAP) ... Plexins are Ras/Rap family GTPase activating proteins (GAPs) and we find that the PlexA GAP domain is phosphorylated by the ... The centrosomal protein RAS association domain family protein 1A (RASSF1A)-binding protein 1 regulates mitotic progression by ... This phosphorylation occurs in the active site of the plexin GTPase-activating protein (GAP) domain, which in turn inhibits ...

... a gene that encodes the Ras-GTPase activating protein neurofibromin. ... Isolation of Adult Human Astrocyte Populations from Fresh-frozen Cortex using Fluorescence-Activated Nuclei Sorting. , ColeCole ... Protein expression of OLIG2, a novel marker in RMS, was investigated utilizing antibody EP112 (Cell Marque). ... Fluorescence-activated nuclei sorting (FANS) can be utilized to efficiently isolate and research human neuronal nuclei (NeuN+) ...

... heat shock protein Hsp90, aminopeptidase N, cell division cycle CDC6, Ras GTPase activating protein (RasGAP), slit guidance ... Inadequate protein intake can impair protein balance and lead to skeletal muscle atrophy, impaired body growth, and functional ... Glucose, urea, total proteins, albumin and NEFA were affected (p , 0.01) by the parturition data-point. There was an ... Furthermore, the average daily milk yield of sampled cows was recorded at 8.7 kg, with fat and protein contents of 3.78% and ...

... the protein product of the NF1 gene, functions at least in part as a GTPase activating protein that regulates Ras proteins by ... Clapps group is also interested in the cellular and biochemical functions of an orphan group of proteins that are involved in ... stimulating their intrinsic GTPase activity. Haploinsufficiency of NF1, via its role in lineages of the tumor microenvironment ...

GTPASE-ACTIVATING PROTEINS PROTEINAS ACTIVADORAS DE GTPASA PROTEÍNAS ATIVADORAS DE RAS GTPASE RAS GTPASE-ACTIVATING PROTEINS ... COATOMER PROTEIN PROTEINA COATOMERA PROTEÍNA P120 ATIVADORA DE GTPASE P120 GTPASE ACTIVATING PROTEIN PROTEINA ACTIVADORA DE ... RAS-GRF1 RAS-GRF1 RAS-GRF1 RECEPTOR DO FATOR DE CRESCIMENTO NEURAL RECEPTOR, NERVE GROWTH FACTOR RECEPTOR DE FACTOR DE ... MITOGEN-ACTIVATED PROTEIN KINASES PROTEINO-QUINASAS MITOGENICA ACTIVADAS PROTEÍNA RAB2 DE LIGAÇÃO A GTP RAB2 GTP-BINDING ...

GTPASE-ACTIVATING PROTEINS PROTEINAS ACTIVADORAS DE GTPASA PROTEÍNAS ATIVADORAS DE RAS GTPASE RAS GTPASE-ACTIVATING PROTEINS ... COATOMER PROTEIN PROTEINA COATOMERA PROTEÍNA P120 ATIVADORA DE GTPASE P120 GTPASE ACTIVATING PROTEIN PROTEINA ACTIVADORA DE ... RAS-GRF1 RAS-GRF1 RAS-GRF1 RECEPTOR DO FATOR DE CRESCIMENTO NEURAL RECEPTOR, NERVE GROWTH FACTOR RECEPTOR DE FACTOR DE ... MITOGEN-ACTIVATED PROTEIN KINASES PROTEINO-QUINASAS MITOGENICA ACTIVADAS PROTEÍNA RAB2 DE LIGAÇÃO A GTP RAB2 GTP-BINDING ...

GTPASE-ACTIVATING PROTEINS PROTEINAS ACTIVADORAS DE GTPASA PROTEÍNAS ATIVADORAS DE RAS GTPASE RAS GTPASE-ACTIVATING PROTEINS ... COATOMER PROTEIN PROTEINA COATOMERA PROTEÍNA P120 ATIVADORA DE GTPASE P120 GTPASE ACTIVATING PROTEIN PROTEINA ACTIVADORA DE ... RAS-GRF1 RAS-GRF1 RAS-GRF1 RECEPTOR DO FATOR DE CRESCIMENTO NEURAL RECEPTOR, NERVE GROWTH FACTOR RECEPTOR DE FACTOR DE ... MITOGEN-ACTIVATED PROTEIN KINASES PROTEINO-QUINASAS MITOGENICA ACTIVADAS PROTEÍNA RAB2 DE LIGAÇÃO A GTP RAB2 GTP-BINDING ...

GTPASE-ACTIVATING PROTEINS PROTEINAS ACTIVADORAS DE GTPASA PROTEÍNAS ATIVADORAS DE RAS GTPASE RAS GTPASE-ACTIVATING PROTEINS ... COATOMER PROTEIN PROTEINA COATOMERA PROTEÍNA P120 ATIVADORA DE GTPASE P120 GTPASE ACTIVATING PROTEIN PROTEINA ACTIVADORA DE ... RAS-GRF1 RAS-GRF1 RAS-GRF1 RECEPTOR DO FATOR DE CRESCIMENTO NEURAL RECEPTOR, NERVE GROWTH FACTOR RECEPTOR DE FACTOR DE ... MITOGEN-ACTIVATED PROTEIN KINASES PROTEINO-QUINASAS MITOGENICA ACTIVADAS PROTEÍNA RAB2 DE LIGAÇÃO A GTP RAB2 GTP-BINDING ...

GTPASE-ACTIVATING PROTEINS PROTEINAS ACTIVADORAS DE GTPASA PROTEÍNAS ATIVADORAS DE RAS GTPASE RAS GTPASE-ACTIVATING PROTEINS ... COATOMER PROTEIN PROTEINA COATOMERA PROTEÍNA P120 ATIVADORA DE GTPASE P120 GTPASE ACTIVATING PROTEIN PROTEINA ACTIVADORA DE ... RAS-GRF1 RAS-GRF1 RAS-GRF1 RECEPTOR DO FATOR DE CRESCIMENTO NEURAL RECEPTOR, NERVE GROWTH FACTOR RECEPTOR DE FACTOR DE ... MITOGEN-ACTIVATED PROTEIN KINASES PROTEINO-QUINASAS MITOGENICA ACTIVADAS PROTEÍNA RAB2 DE LIGAÇÃO A GTP RAB2 GTP-BINDING ...

GTPASE-ACTIVATING PROTEINS PROTEINAS ACTIVADORAS DE GTPASA PROTEÍNAS ATIVADORAS DE RAS GTPASE RAS GTPASE-ACTIVATING PROTEINS ... COATOMER PROTEIN PROTEINA COATOMERA PROTEÍNA P120 ATIVADORA DE GTPASE P120 GTPASE ACTIVATING PROTEIN PROTEINA ACTIVADORA DE ... RAS-GRF1 RAS-GRF1 RAS-GRF1 RECEPTOR DO FATOR DE CRESCIMENTO NEURAL RECEPTOR, NERVE GROWTH FACTOR RECEPTOR DE FACTOR DE ... MITOGEN-ACTIVATED PROTEIN KINASES PROTEINO-QUINASAS MITOGENICA ACTIVADAS PROTEÍNA RAB2 DE LIGAÇÃO A GTP RAB2 GTP-BINDING ...

GTPASE-ACTIVATING PROTEINS PROTEINAS ACTIVADORAS DE GTPASA PROTEÍNAS ATIVADORAS DE RAS GTPASE RAS GTPASE-ACTIVATING PROTEINS ... COATOMER PROTEIN PROTEINA COATOMERA PROTEÍNA P120 ATIVADORA DE GTPASE P120 GTPASE ACTIVATING PROTEIN PROTEINA ACTIVADORA DE ... RAS-GRF1 RAS-GRF1 RAS-GRF1 RECEPTOR DO FATOR DE CRESCIMENTO NEURAL RECEPTOR, NERVE GROWTH FACTOR RECEPTOR DE FACTOR DE ... MITOGEN-ACTIVATED PROTEIN KINASES PROTEINO-QUINASAS MITOGENICA ACTIVADAS PROTEÍNA RAB2 DE LIGAÇÃO A GTP RAB2 GTP-BINDING ...

GTPASE-ACTIVATING PROTEINS PROTEINAS ACTIVADORAS DE GTPASA PROTEÍNAS ATIVADORAS DE RAS GTPASE RAS GTPASE-ACTIVATING PROTEINS ... COATOMER PROTEIN PROTEINA COATOMERA PROTEÍNA P120 ATIVADORA DE GTPASE P120 GTPASE ACTIVATING PROTEIN PROTEINA ACTIVADORA DE ... RAS-GRF1 RAS-GRF1 RAS-GRF1 RECEPTOR DO FATOR DE CRESCIMENTO NEURAL RECEPTOR, NERVE GROWTH FACTOR RECEPTOR DE FACTOR DE ... MITOGEN-ACTIVATED PROTEIN KINASES PROTEINO-QUINASAS MITOGENICA ACTIVADAS PROTEÍNA RAB2 DE LIGAÇÃO A GTP RAB2 GTP-BINDING ...

GTPASE-ACTIVATING PROTEINS PROTEINAS ACTIVADORAS DE GTPASA PROTEÍNAS ATIVADORAS DE RAS GTPASE RAS GTPASE-ACTIVATING PROTEINS ... COATOMER PROTEIN PROTEINA COATOMERA PROTEÍNA P120 ATIVADORA DE GTPASE P120 GTPASE ACTIVATING PROTEIN PROTEINA ACTIVADORA DE ... RAS-GRF1 RAS-GRF1 RAS-GRF1 RECEPTOR DO FATOR DE CRESCIMENTO NEURAL RECEPTOR, NERVE GROWTH FACTOR RECEPTOR DE FACTOR DE ... MITOGEN-ACTIVATED PROTEIN KINASES PROTEINO-QUINASAS MITOGENICA ACTIVADAS PROTEÍNA RAB2 DE LIGAÇÃO A GTP RAB2 GTP-BINDING ...

GTPASE-ACTIVATING PROTEINS PROTEINAS ACTIVADORAS DE GTPASA PROTEÍNAS ATIVADORAS DE RAS GTPASE RAS GTPASE-ACTIVATING PROTEINS ... COATOMER PROTEIN PROTEINA COATOMERA PROTEÍNA P120 ATIVADORA DE GTPASE P120 GTPASE ACTIVATING PROTEIN PROTEINA ACTIVADORA DE ... RAS-GRF1 RAS-GRF1 RAS-GRF1 RECEPTOR DO FATOR DE CRESCIMENTO NEURAL RECEPTOR, NERVE GROWTH FACTOR RECEPTOR DE FACTOR DE ... MITOGEN-ACTIVATED PROTEIN KINASES PROTEINO-QUINASAS MITOGENICA ACTIVADAS PROTEÍNA RAB2 DE LIGAÇÃO A GTP RAB2 GTP-BINDING ...

GTPASE-ACTIVATING PROTEINS PROTEINAS ACTIVADORAS DE GTPASA PROTEÍNAS ATIVADORAS DE RAS GTPASE RAS GTPASE-ACTIVATING PROTEINS ... COATOMER PROTEIN PROTEINA COATOMERA PROTEÍNA P120 ATIVADORA DE GTPASE P120 GTPASE ACTIVATING PROTEIN PROTEINA ACTIVADORA DE ... RAS-GRF1 RAS-GRF1 RAS-GRF1 RECEPTOR DO FATOR DE CRESCIMENTO NEURAL RECEPTOR, NERVE GROWTH FACTOR RECEPTOR DE FACTOR DE ... MITOGEN-ACTIVATED PROTEIN KINASES PROTEINO-QUINASAS MITOGENICA ACTIVADAS PROTEÍNA RAB2 DE LIGAÇÃO A GTP RAB2 GTP-BINDING ...

GTPASE-ACTIVATING PROTEINS PROTEINAS ACTIVADORAS DE GTPASA PROTEÍNAS ATIVADORAS DE RAS GTPASE RAS GTPASE-ACTIVATING PROTEINS ... COATOMER PROTEIN PROTEINA COATOMERA PROTEÍNA P120 ATIVADORA DE GTPASE P120 GTPASE ACTIVATING PROTEIN PROTEINA ACTIVADORA DE ... RAS-GRF1 RAS-GRF1 RAS-GRF1 RECEPTOR DO FATOR DE CRESCIMENTO NEURAL RECEPTOR, NERVE GROWTH FACTOR RECEPTOR DE FACTOR DE ... MITOGEN-ACTIVATED PROTEIN KINASES PROTEINO-QUINASAS MITOGENICA ACTIVADAS PROTEÍNA RAB2 DE LIGAÇÃO A GTP RAB2 GTP-BINDING ...

Ras (E4K9L) Rabbit Monoclonal Antibody (Alexa Fluor® 647 Conjugate) (CST #37182) is ready to ship. ... GTPase-activating proteins (GAPs) normally facilitate the inactivation of Ras. However, research studies have shown that in 30 ... Ras (E4K9L) Rabbit mAb (Alexa Fluor® 647 Conjugate) detects endogenous levels of total K-Ras, H-Ras, and N-Ras proteins. ... The 21 kDa guanine-nucleotide binding proteins (K-Ras, H-Ras, and N-Ras) cycle between active (GTP-bound) and inactive (GDP- ...

... is a complex multidomain protein that activates the small GTPase Ras (H-Ras, K-Ras, N-Ras, but not functionally distinct R-Ras ... Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post ... Nucleotide exchange activity of Sos is stimulated by allosteric Ras binding. By another (separable) guanine exchange factor ... Sos thus integrates signals that affect both gene expression and cytoskeletal reorganization; the Sos-mediated Ras-activation ...

ras GTPase-Activating Proteins 14% * Pathobiology of liver fibrosis. Enis, K.. National Institute of Diabetes and Digestive and ...

ras GTPase-Activating Proteins 32% 147 Scopus citations * RAS pathway activation and an oncogenic RAS mutation in sporadic ... Ras-GTP levels are elevated in human NF1 peripheral nerve tumors. Guha, A., Lau, N., Huvar, I., Gutmann, D., Provias, J., ... Reduced TSC2 RNA and protein in sporadic astrocytomas and ependymomas. Wienecke, R., Guha, A., Maize, J. C., Heideman, R. L., ... Regulation of human cortical interneuron development by the chromatin remodeling protein CHD2. Lewis, E. M. A., Chapman, G., ...

GTP-activating) protein (GAP) for Ras-related GTPase (Rag) C/D, which ultimately activates mTOR (30-32), implicating FLCN as a ... Cairns RA, et al. Regulation of cancer cell metabolism. Nat Rev Cancer. 2011;11(2):85-95.. View this article via: CrossRef ... Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell. 2011;144(5):646-674.. View this article via: CrossRef ... Loss of FLCN in luminal breast cancer cells activates a HIF-1α-dependent angiogenic program in a TFE3-dependent manner. (A-C) ...

synaptic Ras GTPase activating protein 1. 6. Rare Single Gene Mutation, Syndromic. 1. S. 50. ... protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-). 1. Rare Single Gene Mutation, Syndromic. 1. S. 4. ... Ribosomal protein S6 kinase, 90kDa, polypeptide 3. X. Rare Single Gene Mutation, Syndromic. 4. S. 9. ... vacuolar protein sorting 13 homolog B (yeast). 8. Rare Single Gene Mutation, Syndromic. 1. S. 18. ...

synaptic Ras GTPase activating protein 1 Enzyme modulator 145 0.584. 0.577. 1.00. 0.430. None 1.000. 4 0 2010. 2019. ... Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref. ... methyl-CpG binding protein 2 Epigenetic regulator 664 0.414. 0.846. 0.89. 0.500. None 0.919. 62 3 2000. 2019. ... contactin associated protein 2 203 0.530. 0.846. 2.9E-09. 0.500. None 0.975. 40 6 2008. 2019. ...

It shows genes and PPIs with information about pathways, protein-protein interactions (PPIs), Gene Ontology (GO) annotations ... a web resource for human protein-protein interactions. ... synaptic Ras GTPase activating protein 1. multiple PDZ domain ... Protein-Protein Interactions. 13 interactors: CAMK2A DLG3 DLG4 DLGAP4 GRIN1 GRIN2B GRIN2D KDR MPDZ PDGFRB TRIP6 ULK1 ULK2 13 ...

Ras GTPase-activating protein-binding protein 1. G3BP1. Q13283. 1 Reference(s). ... Mitogen-activated protein kinase 8. MAPK8. P45983. 6 Reference(s). T03VS9. Protein-tyrosine kinase 2-beta. PTK2B. Q14289. 1 ... Mitogen-activated protein kinase 1. MAPK1. P28482. 10 Reference(s). T85AXP. Cytochrome P450 3A4. CYP3A4. P08684. 6 Reference(s) ... Ras association domain-containing protein 1. RASSF1. Q9NS23. 1 Reference(s). T34HYH. Interleukin-1 alpha. IL1A. P01583. 2 ...

CHD8 - chromodomain helicase DNA binding protein 8 *SYNGAP1 - synaptic Ras GTPase activating protein 1 ... SYNGAP1 - synaptic Ras GTPase activating protein 1 *DYRK1A - dual specificity tyrosine phosphorylation regulated kinase 1A ...

It shows genes and PPIs with information about pathways, protein-protein interactions (PPIs), Gene Ontology (GO) annotations ... a web resource for human protein-protein interactions. ... RAS p21 protein activator (GTPase activating protein) 1. Image ... Protein-Protein Interactions. 30 interactors: AMPH BIN1 BLM CAMK1 CAMK2G CDK5 CRK ERG GRB2 ITSN2 KAT5 MAPK3 NOS1 NOS1AP PAK1 ...