FDA OKs Pembrolizumab for Adjuvant Treatment of NSCLC
The agency expanded the indication for pembrolizumab to the adjuvant setting for patients with stage IB-IIIA NSCLC following ... Patients had not received neoadjuvant radiotherapy or chemotherapy.. Among the 1010 patients who received adjuvant platinum- ... The US Food and Drug Administration (FDA) approved pembrolizumab (Keytruda) in the adjuvant setting for patients with stage IB- ... Cite this: FDA OKs Pembrolizumab for Adjuvant Treatment of NSCLC - Medscape - Jan 27, 2023. ...
The HIF1α/JMY pathway promotes glioblastoma stem-like cell invasiveness after irradiation | Scientific Reports
Targeting JMY could thus open the way to the development of new therapeutic strategies to improve the efficacy of radiotherapy ... The standard GBM treatment includes surgical resection with adjuvant radiotherapy and chemotherapy2. The radiotherapy treatment ... Stupp, R. et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N. Engl. J. Med. 352, 987-996. https ... Targeting JMY could thus open the way to the development of new therapeutic strategies to improve the efficacy of radiotherapy ...
Nothing of the sufferers had received neo-adjuvant radiotherapy or chemotherapy - Factor Xa inhibitors for primary...
A Phase 3 Randomized Double-Blind Study of Pembrolizumab versus Placebo in Combination with Adjuvant Chemotherapy with or...
... in clinical trial on A Phase 3 Randomized Double-Blind Study of Pembrolizumab versus Placebo in Combination with Adjuvant ... Chemotherapy with or without Radiotherapy for the Treatment of Newly Diagnosed High-Risk Endometrial Carcinoma After Surgery ...
The Evidence of Glioblastoma Heterogeneity | Scientific Reports
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med 352, 987-996 (2005). ... chemotherapy and radiotherapy have been available for decades. The median survival of patients with glioblastoma multiforme ( ...
Assessment of Dose Delivery to Supraclavicular and Axillary Lymph Nodes in Adjuvant Breast Cancer Radiotherapy, with or...
... was examined with radiotherapy dose plan program. An AP planned field suitable for PTV, was designed and compared to AP+PA ... Assessment of Dose Delivery to Supraclavicular and Axillary Lymph Nodes in Adjuvant Breast Cancer Radiotherapy, with or without ... Assessment of Dose Delivery to Supraclavicular and Axillary Lymph Nodes in Adjuvant Breast Cancer Radiotherapy, with or without ... was examined with radiotherapy dose plan program. An AP planned field suitable for PTV, was designed and compared to AP+PA ...
Association of p53 mutations and a codon 72 single nucleotide polymorphism with lower overall survival and responsiveness to...
Women with p53 genetic alterations who did not receive adjuvant radiotherapy had the lowest survival rate (P = 0.0005). Treated ... Among women with p53 alterations, adjuvant radiotherapy substantially increased survival (P = 0.035). In multivariate analyses ... alterations and to evaluate the association of these alterations with clinical outcome and response to adjuvant radiotherapy in ... mutations and a codon 72 single nucleotide polymorphism with lower overall survival and responsiveness to adjuvant radiotherapy ...
Outcome of surgical and adjuvant radiotherapy treatment of T3-T4 squamous cell carcinoma of the floor of the mouth: evaluation...
Outcome of surgical and adjuvant radiotherapy treatment of T3-T4 squamous cell carcinoma of the floor of the mouth: evaluation ... All patients were treated by surgery and adjuvant radiotherapy. The statistical analysis was conducted using the stat-view ... T3-T4 tumours of the floor of the mouth are managed by surgical resection and adjuvant radiotherapy. There is a high rate of ... Outcome of surgical and adjuvant radiotherapy treatment of T3-T4 squamous cell carcinoma of the floor of the mouth: evaluation ...
Overview of adjuvant radiotherapy on survival, failure pattern and toxicity in stage I to II endometrial carcinoma: a long-term...
All patients underwent surgical staging and received adjuvant RT. Patients were divided into groups of low-risk (LR), ... and external beam pelvic radiotherapy (EBRT) with or without VBT on survival in stage I to II EC patients in China from a long- ... This research aimed to provide an overview of the impact of adjuvant vaginal brachytherapy (VBT) ... From: Overview of adjuvant radiotherapy on survival, failure pattern and toxicity in stage I to II endometrial carcinoma: a ...
Prostate Radiotherapy With Adjuvant Androgen Deprivation Therapy (ADT) Improves Metastasis-Free Survival Compared to...
title = "Prostate Radiotherapy With Adjuvant Androgen Deprivation Therapy (ADT) Improves Metastasis-Free Survival Compared to ... T1 - Prostate Radiotherapy With Adjuvant Androgen Deprivation Therapy (ADT) Improves Metastasis-Free Survival Compared to ... Prostate Radiotherapy With Adjuvant Androgen Deprivation Therapy (ADT) Improves Metastasis-Free Survival Compared to ... Prostate Radiotherapy With Adjuvant Androgen Deprivation Therapy (ADT) Improves Metastasis-Free Survival Compared to ...
Search Clinical Trials | Vanderbilt-Ingram Cancer Center
Mortality impact of less-than-standard therapy in older breast cancer patients
Radiotherapy, Adjuvant/methods * Retrospective Studies * Survival Rate/trends * Tamoxifen/therapeutic use * Treatment Outcome ... and the receipt of adjuvant tamoxifen in a large population-based cohort of older women with early-stage disease. STUDY DESIGN ...
Radiation Therapy For Mesothelioma | Types, Side Effects & Survival
The Role of Adjuvant Radiotherapy in Mesothelioma Treatment. ByHolly Zink October 17, 2023. October 5, 2023. ... Read More The Role of Adjuvant Radiotherapy in Mesothelioma Treatment. ... Hemithoracic Radiotherapy for Mesothelioma. ByHolly Zink May 17, 2023. A type of radiation therapy called hemithoracic ... Hemithoracic Radiotherapy for Mesothelioma. ByHolly Zink May 16, 2023. A type of radiation therapy called hemithoracic ...
Are all prostate cancer patients 'fit' for salvage radiotherapy?
Although there are clear criteria (pT3-pT4 disease and/or positive margins) for the use of adjuvant radiotherapy, no specific ... Key Words: Prostate cancer, Salvage radiotherapy, Comorbidity, Fit, Androgen deprivation therapy Core tip: Salvage radiotherapy ... Adjuvant radiotherapy for pathological T3N0M0 prostate cancer significantly reduces risk of metastases and improves survival: ... Table 3 Exclusion criteria in postoperative radiotherapy phase 3 trials. Postoperative radiotherapy. Trial. Exclusion criteria ...
Adrenocortical Carcinoma Treatment (PDQ®) - NCI
Sabolch A, Feng M, Griffith K, et al.: Adjuvant and definitive radiotherapy for adrenocortical carcinoma. Int J Radiat Oncol ... Sabolch A, Feng M, Griffith K, et al.: Adjuvant and definitive radiotherapy for adrenocortical carcinoma. Int J Radiat Oncol ... Adjuvant mitotane (under clinical evaluation).. Although adjuvant mitotane has shown some progression-free or disease-free ... Adjuvant mitotane (under clinical evaluation).. Although adjuvant mitotane has shown some progression-free or disease-free ...
Impact of time to initiation of radiotherapy on survival after resection of newly diagnosed glioblastoma | Radiation Oncology
To evaluate the effect of timing of radiotherapy (RT) on survival in patients with newly diagnosed primary glioblastoma (GBM) ... Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a ... Radiotherapy plus concomitant and adjuvant Temozolomide for glioblastoma. N Engl J Med. 2005;352:987-96 https://doi.org/10.1056 ... Katsigiannis, S., Krischek, B., Barleanu, S. et al. Impact of time to initiation of radiotherapy on survival after resection of ...
Partial breast brachytherapy: MedlinePlus Medical Encyclopedia
Low-dose radiotherapy - breast; High-dose radiotherapy - breast; Electronic balloon brachytherapy; EBB; Intracavitary ... This approach is called adjuvant (additional) radiation therapy because it is adding a treatment beyond surgery. ... Adjuvant partial breast radiation - brachytherapy; APBI - brachytherapy; Accelerated partial breast irradiation - brachytherapy ...
Cancers | Free Full-Text | Combinatorial Effect of PLK1 Inhibition with Temozolomide and Radiation in Glioblastoma
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N. Engl. J. Med. 2005, 352, 987-996. [Google Scholar ...
Search Results - The ASCO Post
Adjuvant Chemoradiotherapy vs Radiotherapy Alone in High-Risk Endometrial Cancer. As reported in The Lancet Oncology by ... Adjuvant Capecitabine After Resection for Biliary Tract Cancer. In the phase III BILCAP trial reported in The Lancet Oncology, ... ctDNA and Recurrence Risk After Surgery and Adjuvant Chemotherapy for Stage III Colon Cancer. In a cohort biomarker study ... In a report published by Garlipp et al in the British Journal of Surgery, the addition of selective internal radiotherapy (SIRT ...
Frontiers | Photothermal Therapy for the Treatment of Glioblastoma: Potential and Preclinical Challenges
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med (2005) 352(10):987-96. doi: 10.1056/ ... followed by radiotherapy and adjuvant plus concomitant chemotherapy with Temozolomide (TMZ) (Stupp protocol) (3). Since 2015, a ... for combined radiotherapy and PTT (40). Heating-dependent sustained release of IUdR was observed in vitro, which could be ...
Fifty-Year-Follow-up Results Compared with Shorter Follow-up of Breast Cancer Patients Undergoing Radical Mastectomy with or...
It is noteworthy that in our extremely long-term follow-up study the cohort with radical mastectomy plus adjuvant radiotherapy ... In contrast, the other three pairs of curves ((b), (c), (d)), in particular, those subjected to adjuvant radiotherapy continue ... Breast Cancer, Cure Rate, Long-Term Follow-up, Radical Mastectomy, Adjuvant Radiotherapy ... Of note, the subgroup undergoing radical mastectomy plus adjuvant radiotherapy has a lower cure rate (67%) than the subgroup ...
Management of colorectal cancer | The BMJ
Optic Nerve Decompression Surgery - Medical Clinical Policy Bulletins | Aetna
Adjuvant radiation therapy in resected high-grade localized skeletal osteosarcomas treated with neoadjuvant chemotherapy
To assess long-term outcomes and toxicity of adjuvant radiotherapy in the post-surgical management of patients with resected ... Seventy-two patients with primary resected osteosarcomas underwent adjuvant radiotherapy after neoadjuvant chemotherapy from ... Mar 9, 2016 , Magazine: Radiotherapy and Oncology Sole CV (1), Calvo FA (2), Alvarez E (3), Cambeiro M (4), Cuervo M (5), San ... A multimodal radiotherapy-containing approach is a well-tolerated component of treatment for patients with osteosarcomas ...
Frontiers | CAR-Engineered NK Cells for the Treatment of Glioblastoma: Turning Innate Effectors Into Precision Tools for Cancer...
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med. (2005) 352:987-96. doi: 10.1056/ ... Long-term follow-up of patients with recurrent malignant gliomas treated with adjuvant adoptive immunotherapy. Neurosurgery. ( ... Intralesional lymphokine-activated killer cells as adjuvant therapy for primary glioblastoma. J Immunother. (2009) 32:914-9. ... T cell activation in the presence of adjuvant temozolomide. Oncoimmunology. (2018) 7:e1412901. doi: 10.1080/2162402X. ...
Thieme E-Journals - Deutsche Zeitschrift für Onkologie / Abstract
et al . Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. The New England Journal of Medicine. 2005; ... and/or radio-therapy is an advanced hyperthermia technique that has been used as adjuvant treatment for patients with malignant ... Retrospective clinical study of adjuvant electro-hyperthermia treatment for advanced brain-gliomas. Hüseyin Sahinbas1 , ... The overall median survival time for patients with mostly advanced malignant glioma who received adjuvant electro-hyperthermia ...
Related Articles | Annals Singapore
Radiotherapy as Local Adjuvant Treatment for Endometrial Carcinoma-A Review of 45 Patients. K M Lee, H S Khoo Tan, M K S Leow, ... Radiotherapy is the mainstay treatment for locally advanced carcinoma of the cervix. It is also administered as an adjuvant ... Radiotherapy as an adjunct to surgery has long been used in the management of endometrial carcinoma with the intent to improve ... A Review of Patients with High-risk Carcinoma of the Cervix Treated with Combined Surgery and Postoperative Radiotherapy. H S ...
Sentinel Lymph Node Biopsy in Nonmelanoma Skin Cancer Patients
... a higher overall survival rate after adjuvant radiotherapy. However, Allen et al. could not demonstrate that an adjuvant ... sentinel lymph node biopsy and adjuvant radiotherapy," Annals of Surgical Oncology, vol. 15, no. 9, pp. 2509-2518, 2008. ... Patient 4 with MCC of the left leg had one metastatic SN (6 mm) out of 2. She refused any further adjuvant therapy. Both MCC N+ ... MCC is known to be radiosensitive, but the systematic use of radiotherapy to the primary tumour and/or the lymph node basin is ...
Vinorelbine and Celecoxib in Treating Women With Relapsed or Metastatic Breast Cancer
Radiotherapy. - At least 4 weeks since prior radiotherapy for metastatic disease. - Prior adjuvant radiotherapy allowed. ... Prior adjuvant or neoadjuvant hormonal therapy allowed. - Prior hormonal therapy for recurrent or metastatic disease allowed. ... Prior adjuvant or neoadjuvant chemotherapy allowed. - Prior chemotherapy for recurrent or metastatic disease allowed. - No ...
Vitreous relapse following primary chemotherapy for retinoblastoma: is adjuvant diode laser a risk factor? | British Journal of...
EBRT, external beam radiotherapy. *ILM, internal limiting membrane. *TTT, transpupillary thermotherapy. *retinoblastoma ... Vitreous relapse following primary chemotherapy for retinoblastoma: is adjuvant diode laser a risk factor? ... Vitreous relapse following primary chemotherapy for retinoblastoma: is adjuvant diode laser a risk factor? ... including adjuvant diode laser), and ocular preservation. Individual tumour foci treated with laser hyperthermia were also ...