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*  Inhibition of purine nucleoside phosphorylase by 8-aminoguanosine: selective toxicity for T lymphoblasts | Science
Inhibition of purine nucleoside phosphorylase by 8-aminoguanosine: selective toxicity for T lymphoblasts ... Inhibition of purine nucleoside phosphorylase by 8-aminoguanosine: selective toxicity for T lymphoblasts ... Inhibition of purine nucleoside phosphorylase by 8-aminoguanosine: selective toxicity for T lymphoblasts ... Inhibition of purine nucleoside phosphorylase by 8-aminoguanosine: selective toxicity for T lymphoblasts ...
http://science.sciencemag.org/content/214/4525/1137
*  Effects of some modulators on purine nucleoside phosphorylase activity in myocardial tissue
Purine nucleoside phosphorylase (PNP) in mammalian tissue is an enzyme responsible for formation of purine bases in DNA. It is ... Effects of some modulators on purine nucleoside phosphorylase activity in myocardial tissue. Åberg, Anna-Maja ... Analytical chemistry, myocardium, purine-nucleoside phosphorylase, enzyme activity, myocardial ischemia National Category ...
http://uu.diva-portal.org/smash/record.jsf?pid=diva2:303989
*  β-deuterium kinetic isotope effects in the purine nucleoside phosphorylase reaction | Biochemical Journal
β-deuterium kinetic isotope effects in the purine nucleoside phosphorylase reaction. X M Guo, M Ashwell, M L Sinnott, T A ... β-deuterium kinetic isotope effects in the purine nucleoside phosphorylase reaction. X M Guo, M Ashwell, M L Sinnott, T A ... β-deuterium kinetic isotope effects in the purine nucleoside phosphorylase reaction Message Subject (Your Name) has forwarded a ... for phosphorolysis of this compound by the purine nucleoside phosphorylase of Escherichia coli as a function of pH. 3. The pH ...
http://www.biochemj.org/content/278/2/487
*  Bromine in the structure of Crystal Structure of Schistosoma Mansoni Purine Nucleoside Phosphorylase Complexed With A Novel...
Crystal Structure of Schistosoma Mansoni Purine Nucleoside Phosphorylase Complexed With A Novel Monocyclic Inhibitor ... The binding sites of Bromine atom in the structure of Crystal Structure of Schistosoma Mansoni Purine Nucleoside Phosphorylase ... Bromine in the structure of Crystal Structure of Schistosoma Mansoni Purine Nucleoside Phosphorylase Complexed With A Novel ...
http://bromine.atomistry.com/pdb3e0q.html
*  Adenosine deaminase deficiency | Genetic and Rare Diseases Information Center (GARD) - an NCATS Program
Purine Nucleoside Phosphorylase Deficiency. Medscape Reference. July 2013; http://emedicine.medscape.com/article/887823- ...
https://rarediseases.info.nih.gov/diseases/5748/disease
*  RCSB PDB - Protein Feature View - Purine nucleoside phosphorylase - P00491 (PNPH HUMAN)
The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy) ... ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. UniProt ...
http://www.rcsb.org/pdb/protein/P00491
*  RCSB PDB - Protein Feature View - Purine nucleoside phosphorylase DeoD-type - Q5DYV8 (DEOD3 VIBF1)
Purine deoxynucleoside + phosphate = purine + 2'-deoxy-alpha-D-ribose 1-phosphate. UniProt ...
http://www.rcsb.org/pdb/protein/Q5DYV8
*  xapA - Purine nucleoside phosphorylase 2 - Escherichia coli (strain K12) - xapA gene & protein
This protein can degrade all purine nucleosides including xanthosine, inosine and guanosine, but cannot cleave adenosine, ... with the formation of the corresponding free purine bases and pentose-1-phosphate. ... The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy) ... phosphorylase_d. IPR035994. Nucleoside_phosphorylase_sf. IPR011268. Purine_phosphorylase. IPR018099. Purine_phosphorylase-2_CS ...
http://www.uniprot.org/uniprot/P45563
*  Purine Nucleoside Phosphorylase: Kinetics, Mechanism, and Specificity | Molecular Pharmacology
Ribosyl exchange reactions between purines and purine nucleosides catalyzed by crystalline purine nucleoside phosphorylase from ... Purine Nucleoside Phosphorylase: Kinetics, Mechanism, and Specificity Message Subject (Your Name) has forwarded a page to you ... An ordered sequential mechanism involving the isomerization of time free enzyme and the initial combination of the purine base ... The specificity of the enzyme toward the purine base in the synthesis of ribonucleosides was investigated. In order of ...
http://molpharm.aspetjournals.org/content/3/6/526
*  Purine nucleoside phosphorylase - Wikipedia
... purine deoxynucleoside phosphorylase, purine deoxyribonucleoside phosphorylase, purine nucleoside phosphorylase, and purine ... a purine-nucleoside phosphorylase (EC 2.4.2.1) is an enzyme that catalyzes the chemical reaction purine nucleoside + phosphate ... Purine nucleoside phosphorylase (PNP) also known as PNPase and inosine phosphorylase is an enzyme that in humans is encoded by ... Purine nucleoside phosphorylase is an enzyme involved in purine metabolism. PNP metabolizes inosine into hypoxanthine and ...
https://en.wikipedia.org/wiki/Purine_nucleoside_phosphorylase
*  deoD - Purine nucleoside phosphorylase DeoD-type - Helicobacter pylori (strain ATCC 700392 / 26695) - deoD gene & protein
IPR018016. Nucleoside_phosphorylase_CS. IPR000845. Nucleoside_phosphorylase_d. IPR035994. Nucleoside_phosphorylase_sf. ... IPR018016. Nucleoside_phosphorylase_CS. IPR000845. Nucleoside_phosphorylase_d. IPR035994. Nucleoside_phosphorylase_sf. ... Purine nucleoside phosphorylase DeoD-typeAdd BLAST. 233. Proteomic databases. PaxDb, a database of protein abundance averages ... Purine nucleoside phosphorylase DeoD-typeUniRule annotation. ,p>Manual validated information which has been generated by the ...
http://www.uniprot.org/uniprot/P56463
*  Purine nucleoside phosphorylase deficiency - Wikipedia
Purine nucleoside phosphorylase deficiency, often called PNP-deficiency, is a rare autosomal recessive metabolic disorder which ... The disorder is caused by a mutation of the purine nucleoside phosphorylase (PNP) gene, located at chromosome 14q13.1. PNP is a ... Markert ML (1991). "Purine nucleoside phosphorylase deficiency". Immunodefic Rev. 3 (1): 45-81. PMID 1931007. Online Mendelian ... Toro A, Grunebaum E (Oct 2006). "TAT-mediated intracellular delivery of purine nucleoside phosphorylase corrects its deficiency ...
https://en.wikipedia.org/wiki/Purine_nucleoside_phosphorylase_deficiency
*  PDB-1a9p: BOVINE PURINE NUCLEOSIDE PHOSPHORYLASE COMPLEXED WITH 9-DEAZAINOS... - Yorodumi
Purine salvage / Purine catabolism / purine-nucleoside phosphorylase activity / purine-nucleoside phosphorylase / nucleoside ... Purine catabolism .... >>. Purine nucleoside phosphorylase / Nucleoside phosphorylase domain / Purine nucleoside phosphorylase ... PURINE NUCLEOSIDE PHOSPHORYLASE. Function / homology. Purine nucleoside phosphorylase / Nucleoside phosphorylase domain / ... Purine nucleoside phosphorylase I, inosine/guanosine-specific / Purine phosphorylase, family 2, conserved site / Nucleoside ...
https://pdbj.org/emnavi/quick.php?id=pdb-1a9p
*  Unraveling the structural and functional differences between purine nucleoside phosphorylase and 5'-deoxy-5'...
Purine nucleoside metabolism in the archaeon Pyrococcus furiosus is catalyzed by purine nucleoside phosphorylase (PfPNP) and 5 ... methylthioadenosine phosphorylase and human purine nucleoside phosphorylase, residue changes at level of the same crucial ... Purine-Nucleoside Phosphorylase/chemistry*. *Purine-Nucleoside Phosphorylase/genetics. *Purine-Nucleoside Phosphorylase/ ... Unraveling the structural and functional differences between purine nucleoside phosphorylase and 5'-deoxy-5'- ...
https://www.ncbi.nlm.nih.gov/pubmed/21683167
*  Development of an enzyme cycling method by a purine nucleoside phosphorylase for assaying inorganic phosphate - Analytical...
Development of an enzyme cycling method by a purine nucleoside phosphorylase for assaying inorganic phosphate†. Shigeru Ueda * ... We have developed a novel enzymatic cycling method that uses purine nucleoside phosphorylase (PNP) (EC 2.4.2.1) from Bacillus ... Here, we attempted to expand the application of the principle to purine nucleoside phosphorylase (PNP) (EC 2.4.2.1), a ... Deoxy) purine nucleoside + Pi = purine base + (deoxy) ribose-1-phosphate (R-1-P). ...
http://pubs.rsc.org/en/content/articlehtml/2017/ay/c7ay02016c
*  Role of Purine Nucleoside Phosphorylase in Interactions between 2′,3′-Dideoxyinosine and Allopurinol, Ganciclovir, or Tenofovir
Inhibition of human purine nucleoside phosphorylase by acyclic nucleosides and nucleotides. Biochem. Pharmacol. 36:1237-1244. [ ... Antiviral acyclic nucleoside phosphonate analogues as inhibitors of purine nucleoside phosphorylase. Adv. Exp. Med. Biol. 431: ... Human erythrocytic purine nucleoside phosphorylase: reaction with sugar-modified nucleoside substrates. Biochemistry 19:102-107 ... Interactions of calf spleen purine nucleoside phosphorylase with antiviral acyclic nucleoside phosphonate inhibitors: kinetics ...
http://pubmedcentralcanada.ca/pmcc/articles/PMC375307/?lang=en-ca
*  A proof-of-principle pharmacokinetic, pharmacodynamic, and clinical study with purine nucleoside phosphorylase inhibitor...
The discovery of purine nucleoside phosphorylase (PNP) deficiency and T lymphocytopenia suggested that inhibition of this ... A proof-of-principle pharmacokinetic, pharmacodynamic, and clinical study with purine nucleoside phosphorylase inhibitor ...
https://www.sigmaaldrich.com/catalog/papers/16131572
*  AID 386684 - Inhibition of Plasmodium falciparum purine nucleoside phosphorylase assessed as slow onset inhibition constant by...
Inhibition of Plasmodium falciparum purine nucleoside phosphorylase assessed as slow onset inhibition constant by xanthine- ...
https://pubchem.ncbi.nlm.nih.gov/bioassay/386684
*  Human purine nucleoside phosphorylase - SynPharm
mengytyedykntaewllshtkhrpqvaiicgSglggltdkltqaqifdyseipnfprstvpghagrlvfgflngracvmmqgrfHmYegyplwkvtfpvrvfhllgvdtlvvtnAagglnpkfevgdimlirdhinlpgfsgqnplrgpnderfgdrFpamsdaydrtmrqralstwkqmgeqrelqegtyvmvagpsFEtvaecrvlqklgadavGMstvpevivarhcglrvfgfsliTNkVimdyeslekanHeevlaagkqaaqkleqfvsilmasiplpdkas ...
https://synpharm.guidetopharmacology.org/sequences/detail.jsp?id=81910
*  Grouper Iridovirus Purine Nucleoside Phosphorylase
Purine nucleoside phosphorylase (PNP) catalyzes the reversible phosphorolysis of purine ribonucleosides to the corresponding ... Crystal Structure of Grouper Iridovirus Purine Nucleoside Phosphorylase.Acta Crystallogr. D 66:155-162 (2010). ...
http://arginine.chem.cornell.edu/Structures2/GIVPNP.html
*  Localization of adenosine deaminase [ADA] and purine nucleoside phosphorylase [PNP] in human hepatic and renal tissues -...
lymphatic tissue nucleoside adenosine man endothelial cell purine nucleoside phosphorylase hepatic tissue kidney liver renal ... Localization of adenosine deaminase [ADA] and purine nucleoside phosphorylase [PNP] in human hepatic and renal tissues - ...
http://yadda.icm.edu.pl/yadda/element/bwmeta1.element.agro-article-cba12959-a2fa-4715-b78d-0db6a7fb4ac8
*  Purine Nucleoside Phosphorylase Deficiency - Turf Toe
purine nucleoside phosphorylase deficiency , distinguish between purines and pyrimidines , purine nucleotides and pyrimidine ... Contact Us , About Us , Privacy Policy , RSS Feed , purine nucleoside phosphorylase deficiency ... Many foods contain purines especially seafood and meat. Unless a patient has a family history or is taking medication that can ... The list of high purine food is actually quite long thus it is very important for gout patients to be wary of the food they ...
http://gout-remedies.net/kwfe.aspx