Therapeutic importance of sulfated polysaccharides from seaweeds: updating the recent findings | 3 BiotechTherapeutic importance of sulfated polysaccharides from seaweeds: updating the recent findings | 3 Biotech
... inhibits TGF-beta1-induced pulmonary fibrosis in vitro and bleomycin-induced pulmonary fibrosis in vivo. The oligosaccharide ... MS80 proved to be a potent suppressor of bleomycin-induced rat pulmonary fibrosis in vivo (Jiang and Guan 2009). Du et al. ( ... 2012). Idiopathic pulmonary fibrosis is a pathological condition characterized by accumulation of excess fibroblasts, ... Jiang HD, Guan HS (2009) MS80, a novel sulfated oligosaccharide, inhibits pulmonary fibrosis by targeting TGF-beta1 both in ...
https://link.springer.com/article/10.1007/s13205-012-0061-9
Australasian interstitial lung disease registry (AILDR): objectives, design and rationale of a bi-national prospective database...Australasian interstitial lung disease registry (AILDR): objectives, design and rationale of a bi-national prospective database...
Idiopathic pulmonary fibrosis (31%) and connective-tissue disease related ILD (21.7%) were the two most common subtypes. ... The Idiopathic Pulmonary Fibrosis Clinical Research Network. Prednisone, azathioprine, and N-Acetylcysteine for pulmonary ... Diagnosis of idiopathic pulmonary fibrosis. an official ATS/ERS/JRS/ALAT clinical practice guideline. Am J Respir Crit Care Med ... Raghu G. Idiopathic pulmonary fibrosis: lessons from clinical trials over the past 25 years. Eur Respir J. 2017;50(4):1701209. ...
https://link.springer.com/article/10.1186/s12890-020-01297-2
Expanding roles for leukotrienes in airway inflammation | SpringerLinkExpanding roles for leukotrienes in airway inflammation | SpringerLink
Peters-Golden M, Bailie M, Marshall T, et al.: Protection from pulmonary fibrosis in leukotriene-deficient mice. Am J Respir ... the role of the cysteinyl leukotriene 2 receptor in increased vascular permeability and in bleomycin-induced pulmonary fibrosis ... Kim DC, Hsu FI, Barrett NA, et al.: Cysteinyl leukotrienes regulate Th2 cell-dependent pulmonary inflammation. J Immunol 2006, ... Division of Pulmonary and Critical Care Medicine, 6301 MSRB III, 1150 West Medical Center Drive, Ann Arbor, MI, 48109-5642, USA ...
https://link.springer.com/article/10.1007/s11882-008-0057-z?error=cookies_not_supported&code=a0891d6c-71a5-46cd-84d6-cda2a6c5bc4c
Adverse Drug Effects and Their Clinical Management: A Personal View | Drug SafetyAdverse Drug Effects and Their Clinical Management: A Personal View | Drug Safety
Examples are pulmonary fibrosis, which will usually need corticosteroid and even immunosuppressive therapy, and acute renal and ...
https://link.springer.com/article/10.1007/s40264-014-0167-6?error=cookies_not_supported&code=25d0c15c-1455-4347-aa6f-be4f9791c4e1
In vivo uptake and cellular distribution of gold nanoshells in a preclinical model of xenografted human renal cancer | Gold...In vivo uptake and cellular distribution of gold nanoshells in a preclinical model of xenografted human renal cancer | Gold...
... and life-threatening damages such as diffuse pulmonary fibrosis, and bone marrow aplasia. These severe complications linked to ... diffuse interstitial fibrosis and inflammatory infiltrate in the lung; and possible bone marrow fibrosis or brain damage. ... fibrosis and inflammatory infiltrate in the liver; glomerular sclerosis and interstitial fibrosis with inflammatory infiltrate ... No interstitial fibrosis or inflammatory infiltrate was detected in the lung or heart, whether at early or late time points ( ...
https://link.springer.com/article/10.1007/s13404-013-0115-8
TGF-β1 increases permeability of ciliated airway epithelia via redistribution of claudin 3 from tight junction into cell nuclei...TGF-β1 increases permeability of ciliated airway epithelia via redistribution of claudin 3 from tight junction into cell nuclei...
... development of an in vitro model of respiratory epithelial cells in idiopathic pulmonary fibrosis. J Pharmacol Toxicol Methods ... and it plays a major role in lung fibrosis and emphysema. Furthermore, more recent studies demonstrated that TGF-β1 signalling ...
https://link.springer.com/article/10.1007/s00424-020-02501-2
ALMS1 and Alström syndrome: a recessive form of metabolic, neurosensory and cardiac deficits | Journal of Molecular MedicineALMS1 and Alström syndrome: a recessive form of metabolic, neurosensory and cardiac deficits | Journal of Molecular Medicine
... neurological disturbances and fibrosis [48, 52, 78]. Moreover, data implicating pancreatic β cell primary cilia in the ... renal and pulmonary dysfunction, chronic otitis media in childhood, abnormal spinal curvature (scoliosis, kyphosis or lordosis ... dilated cardiomyopathy and multi-organ fibrosis. Elucidating the function of the mutated gene, ALMS1, is critical for the ... Fibrosis of multiple organs is a common finding [4]. ...
https://link.springer.com/article/10.1007/s00109-018-1714-x
Essentials in saline pharmacology for nasal or respiratory hygiene in times of COVID-19 | European Journal of Clinical...Essentials in saline pharmacology for nasal or respiratory hygiene in times of COVID-19 | European Journal of Clinical...
Takano H (2020) Pulmonary surfactant itself must be a strong defender against SARS-CoV-2. Medical Hypotheses 144:110020. https ... Wills PJ, Hall RL, Wm C, Cole PJ (1997) Sodium chloride increases the ciliary transportability of cystic fibrosis and ... Wheatley CM, Cassuto NA, Foxx-Lupo WT et al (2010) Variability in measures of exhaled breath Na+, influence of pulmonary blood ... SARS-CoV-2 attacks the AT2 cells, causing defective functionality of these cells, which may cause exhaustion of pulmonary ...
https://link.springer.com/article/10.1007/s00228-021-03102-3
Shifting paradigms of nontuberculous mycobacteria in cystic fibrosis | Respiratory ResearchShifting paradigms of nontuberculous mycobacteria in cystic fibrosis | Respiratory Research
These shifts are likely to benefit the management of all patients with pulmonary NTM, regardless of underlying pathology. ... are currently shifting based on an increasing attention within the field of cystic fibrosis (CF). ... Important paradigms of pulmonary disease with nontuberculous mycobacteria (NTM) ... Announced as the most important emerging threat to cystic fibrosis (CF) patients at the 2013 European Cystic Fibrosis ...
https://link.springer.com/article/10.1186/1465-9921-15-41
Inhibition of the activity of matrix metalloproteinase 2 by triethylene glycol dimethacrylate | Clinical Oral InvestigationsInhibition of the activity of matrix metalloproteinase 2 by triethylene glycol dimethacrylate | Clinical Oral Investigations
Matrix remodeling response of human periodontal tissue cells toward fibrosis upon nicotine exposure Article 15 October 2014 ... Cytotoxicity of the dental composite component TEGDMA and selected metabolic by-products in human pulmonary cells. Dent Mater ...
https://link.springer.com/article/10.1007/s00784-010-0443-5?error=cookies_not_supported&code=30be2c69-d4ae-4e32-9a55-b3a0692c476b
Immunological impact of graphene oxide sheets in the abdominal cavity is governed by surface reactivity | Archives of ToxicologyImmunological impact of graphene oxide sheets in the abdominal cavity is governed by surface reactivity | Archives of Toxicology
Finally, the pulmonary safety profile of large GO sheets cannot be drawn solely on the present results using the ... neither l-GO nor s-GO seemed to induce significant or visible granulomatous inflammation on the mesothelium or fibrosis at any ... 2013a). However, whilst the i.p. model has been fully validated to predict the potential pulmonary harm caused by natural ... Donaldson K, Murphy F, Schinwald A et al (2011) Identifying the pulmonary hazard of high aspect ratio nanoparticles to enable ...
https://link.springer.com/article/10.1007/s00204-018-2303-z
A Review of Predictive and Contrastive Self-supervised Learning for Medical Images | Machine Intelligence ResearchA Review of Predictive and Contrastive Self-supervised Learning for Medical Images | Machine Intelligence Research
Liver fibrosis and NAS scoring from CT images using self-supervised learning and texture encoding. In Proceedings of the 18th ... Seeking an optimal approach for computer-aided pulmonary embolism detection. In Proceedings of the 12th International Workshop ... Accurate and robust pulmonary nodule detection by 3D feature pyramid network with self-supervised feature learning. [Online], ...
https://link.springer.com/article/10.1007/s11633-022-1406-4
Risk factors for the recurrence of relapsing polychondritis | Arthritis Research & TherapyRisk factors for the recurrence of relapsing polychondritis | Arthritis Research & Therapy
Pulmonary function in patients with relapsing polychondritis. Chest. 1982;81:711-7. ... chronic repetitive inflammation can cause irreversible destruction and fibrosis of the trachea, resulting in a high risk of ...
https://link.springer.com/article/10.1186/s13075-022-02810-0
Evolving Role of Vitamin D in Immune-Mediated Disease and Its Implications in Autoimmune Hepatitis | SpringerLinkEvolving Role of Vitamin D in Immune-Mediated Disease and Its Implications in Autoimmune Hepatitis | SpringerLink
Vitamin D inhibits development of liver fibrosis in an animal model but cannot ameliorate established cirrhosis. Am J Physiol ... Metabolism of 25-hydroxyvitamin D3 by cultured pulmonary alveolar macrophages in sarcoidosis. J Clin Invest. 1983;72:1856-1860. ... Beyazit Y, Kocak E, Tanoglu A, Kekilli M. Oxidative stress might play a role in low serum vitamin D associated liver fibrosis ... Low vitamin D serum level is related to severe fibrosis and low responsiveness to interferon-based therapy in genotype 1 ...
https://link.springer.com/article/10.1007/s10620-018-5351-6?error=cookies_not_supported&code=6475bd1b-5d51-42ac-b16a-93df0268662b
Role of Nrf2/HO-1 system in development, oxidative stress response and diseases: an evolutionarily conserved mechanism |...Role of Nrf2/HO-1 system in development, oxidative stress response and diseases: an evolutionarily conserved mechanism |...
Down-regulated NF-E2-related factor 2 in pulmonary macrophages of aged smokers and patients with chronic obstructive pulmonary ... fibrosis, and angiogenesis. Iron is known to facilitate the generation of reactive oxygen species through Fenton reaction and ...
https://link.springer.com/article/10.1007/s00018-016-2223-0