The transcription factor c-Jun protects against sustained hepatic endoplasmic reticulum stress thereby promoting hepatocyte...
Proto-Oncogene Proteins c-jun/physiology*. Substance. *Proto-Oncogene Proteins c-jun ... ER stress was induced pharmacologically in vitro and in vivo and resulted in a rapid and robust induction of c-Jun protein ... activating protein 1) transcription factor c-Jun is a prototypic JNK target and important regulator of hepatocyte survival, ... Moreover, sustained ER stress in hepatocytes lacking c-Jun resulted in increased cell damage and apoptosis. ER stress is also a ...https://www.ncbi.nlm.nih.gov/pubmed/21953113?dopt=Abstract
DNAJB4 | Cancer Genetics Web
Proto-Oncogene Proteins c-jun. *Transcription Factor AP-1. *Adenocarcinoma. *Gene Enhancer Elements ... protein binding - protein folding - response to heat - response to unfolded protein - unfolded protein binding Data from Gene ... early unfolded protein response signaling (phospho-PERK, phospho-eIF2α, CHOP (CCAAT/enhancer-binding protein homologous protein ... What does this gene/protein do?. Show (10). DNAJB4 is implicated in:. - cytoplasm - heat shock protein binding - nucleolus - ...http://www.cancerindex.org/geneweb/DNAJB4.htm
Jun proteins modulate the ovary-specific promoter of aromatase gene in ovarian granulosa cells via a cAMP-responsive element.
Genes, jun. Granulosa Cells. Mice. Promoter Regions, Genetic*. Proto-Oncogene Proteins c-jun / genetics, metabolism*. ... 0/Proto-Oncogene Proteins c-jun; 60-92-4/Cyclic AMP; EC 18.104.22.168/Aromatase ... The Jun-mediated repression was specific to the aromatase promoter, as Jun proteins stimulated known AP1-responsive promoters ... we unraveled an important role of Jun proteins in modulating ovary-specific aromatase expression. Ectopic expression of the Jun ...http://www.biomedsearch.com/nih/Jun-proteins-modulate-ovary-specific/15688015.html
Molecular mechanism of c-jun antisense gene transfection in alleviating injury of cardiomyocytes treated with burn serum and...
To explore the molecular mechanism of c-jun antisense gene transfection in alleviating injury of cardiomyocytes treated with ... JNK Mitogen-Activated Protein Kinases / metabolism. Myocytes, Cardiac / metabolism*. Proto-Oncogene Proteins c-jun / metabolism ... 0/Proto-Oncogene Proteins c-jun; 0/Troponin T; 0/Tubulin; EC 22.214.171.124/JNK Mitogen-Activated Protein Kinases ... Expression of troponin T and beta-tubulin protein, c-jun protein, protein kinase Ca (PKCa), and c-jun N-terminal kinase (JNK) ...http://www.biomedsearch.com/nih/Molecular-mechanism-c-jun-antisense/15573245.html
ISL-1 promotes NHL cells proliferation and affects cell | Open-i
LIM-Homeodomain Proteins/genetics/metabolism*. *Lymphoma, Non-Hodgkin/metabolism*/pathology*. *Proto-Oncogene Proteins c-jun/ ... ChIP, Co-IP and ChIP-re-IP analysis revealed that ISL-1 could participate with p-STAT3 and p-c-Jun to form a p-STAT3/p-c-Jun/ ... ChIP, Co-IP and ChIP-re-IP analysis revealed that ISL-1 could participate with p-STAT3 and p-c-Jun to form a p-STAT3/p-c-Jun/ ... When ISL-1 protein level was up or down-regulated, notable promotion or inhibition of cell growth were observed in ...https://openi.nlm.nih.gov/detailedresult.php?img=PMC4125377_1476-4598-13-181-2&req=4
C) Aliquots of formaldehyde crosslinked mononucleosome | Open-i
Proto-Oncogene Proteins c-fos/genetics/metabolism. *Proto-Oncogene Proteins c-jun/genetics/metabolism ... Proto-Oncogene Proteins c-fos/genetics/metabolism. *Proto-Oncogene Proteins c-jun/genetics/metabolism ... Recovery of c-fos, c-jun and hbb coding region sequences were quantified by real-time PCR. Average % input recoveries and s.d. ... Recovery of c-fos, c-jun and hbb coding region sequences were quantified by real-time PCR. Average % input recoveries and s.d. ...https://openi.nlm.nih.gov/detailedresult.php?img=PMC2168397_7601967f5b&req=4
HKU Scholars Hub: Induction of c-Jun phosphorylation in spinal motoneurons in neonatal and adult rats following axonal injury
Proto-Oncogene Proteins C-Jun - Metabolism. en_US. dc.subject.mesh. Rats. en_US. ... We further showed that expression of p-c-Jun was not correlated with the expression of growth-associated protein-43 (GAP-43), ... We further showed that expression of p-c-Jun was not correlated with the expression of growth-associated protein-43 (GAP-43), ... p-c-Jun) and almost all injured motoneurons in these animals died. Similarly, root avulsion in adult rats also induced p-c-Jun ...http://hub.hku.hk/handle/10722/149732
melanoma of the cornea drug therapy 2000:2010[pubdate] *count=100 - BioMedLib™ search engine
Genes, jun. Melanoma, Experimental / drug therapy. Neovascularization, Pathologic / drug therapy. Proto-Oncogene Proteins c-jun ... Proto-Oncogene Proteins c-jun; 0 / Vascular Endothelial Growth Factor A; EC 126.96.36.199 / Matrix Metalloproteinase 2 ... Mitogen-Activated Protein Kinase 1 / metabolism. Mitogen-Activated Protein Kinase 3. Mitogen-Activated Protein Kinases / ... Mitogen-Activated Protein Kinase 1; EC 188.8.131.52 / Mitogen-Activated Protein Kinase 3; EC 184.108.40.206 / Mitogen-Activated Protein ...http://www.bmlsearch.com/?kwr=melanoma+of+the+cornea+drug+therapy+2000:2010%5Bpubdate%5D&cxts=100&stmp=b1
"Activation of the mouse Ig germline epsilon promoter by IL-4 is depend" by Ching-Hung Shen and Janet Stavnezer
We demonstrate that AP-1 (Fos and Jun), induced transiently by CD40 ligand or LPS, binds a DNA element in the mouse GL epsilon ... Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; STAT6 Transcription Factor; Signal Transduction; Spleen; Trans- ... We demonstrate that AP-1 (Fos and Jun), induced transiently by CD40 ligand or LPS, binds a DNA element in the mouse GL epsilon ... Adjuvants, Immunologic; Animals; B-Lymphocytes; Base Sequence; CCAAT-Enhancer-Binding Proteins; CD40 Ligand; Cell Line; Cells, ...https://escholarship.umassmed.edu/wfc_pp/189/
"Role of the JNK Signal Transduction Pathway in Cell Survival: a Disser" by Jennifer A. Lamb
JNK phosphorylates the amino terminal domain of all three Jun transcription factors (JunB, c-Jun and JunD) all members of the ... are evolutionarily conserved serine/threonine protein kinases that are activated by proinflammatory cytokines, environmental ... Signal Transduction; Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-jun; Cell Survival; Transcription Factor AP-1 ... The c-Jun NH2-terminal kinases (JNK) are evolutionarily conserved serine/threonine protein kinases that are activated by ...https://escholarship.umassmed.edu/gsbs_diss/232/
Search Articles | University of Toronto Libraries
Proto-Oncogene Proteins - physiology , Survival Analysis , Mice , Microscopy, Fluorescence , Proto-Oncogene Proteins c-jun , ... PROTEINS , CELL BIOLOGY , Signal Transduction , Proto-Oncogene Proteins c-jun - genetics , Oxidative Stress - physiology , ... DNA-Binding Proteins - deficiency , Protein Subunits - metabolism , DNA-Binding Proteins - metabolism , SMARCB1 Protein , ... Proto-Oncogene Proteins - deficiency , Mice, Knockout , Locomotion , Mammary Neoplasms, Animal - pathology , Animals , ...https://query.library.utoronto.ca/index.php/search/q?kw=Author:Bourachot,%20Brigitte
CRK CRK proto-oncogene, adaptor protein [Homo sapiens (human)] - Gene - NCBI
Biophys J, 2016 Jun 21. PMID 27332121, Free PMC Article * Reciprocal regulation of Abl kinase by Crk Y251 and Abi1 controls ... CRK CRK proto-oncogene, adaptor protein [Homo sapiens] CRK CRK proto-oncogene, adaptor protein [Homo sapiens]. Gene ID:1398 ... proto-oncogene c-Crk. v-crk avian sarcoma virus CT10 oncogene homolog. v-crk sarcoma virus CT10 oncogene-like protein. ... CRK proto-oncogene, adaptor proteinprovided by HGNC. Primary source. HGNC:HGNC:2362 See related. Ensembl:ENSG00000167193 MIM: ...https://www.ncbi.nlm.nih.gov/gene/1398
HRAS - HRas proto-oncogene, GTPase - Bos taurus (Bovine) - HRAS gene & protein
Entry version 57 (20 Jun 2018). Sequence version 1 (16 Nov 2011). Previous versions , rss ... Protein-protein interaction databases. STRING: functional protein association networks. More...STRINGi. 9913.ENSBTAP00000055845 ... Protein-protein interaction databases. STRING: functional protein association networks. More...STRINGi. 9913.ENSBTAP00000055845 ... Protein predictedi ,p>This indicates the type of evidence that supports the existence of the protein. Note that the protein ...https://www.uniprot.org/uniprot/G3N1U2
Lck - Proto-oncogene tyrosine-protein kinase LCK - Mus musculus (Mouse) - Lck gene & protein
Last modified:June 10, 2008 - v1. ,p>The checksum is a form of redundancy check that is calculated from the sequence. It is ... Proto-oncogene tyrosine-protein kinase LCKImported. ,p>Information which has been imported from another database using ... tr,B2KG65,B2KG65_MOUSE Proto-oncogene tyrosine-protein kinase LCK (Fragment) OS=Mus musculus GN=Lck PE=4 SV=1 ... Protein. Similar proteins. Organisms. Length. Cluster ID. Cluster name. Size. B2KG65. P06241. H2QTK7. F7FVL2. G7P3M8. G1TA73. ...http://www.uniprot.org/uniprot/B2KG65
Protein focus | InterPro | EMBL-EBI
We combine protein signatures from a number of member databases into a single searchable resource, capitalising on their ... InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites ... July: SRC, proto-oncogene tyrosine-protein kinase. June: Green fluorescent protein To top ... InterPro protein focus. Protein Focus (formally known as Protein of the Month) explores the function and family relationships ...http://www.ebi.ac.uk/interpro/protein-focus
Expression of Proto-oncogenes and Gene Mutation of Sarcomeric Proteins in Patients With Hypertrophic Cardiomyopathy |...
Reiss K, Capasso MJ, Huang HE, Meggs LG, Li P, Anversa P. ANG II receptors, c-myc, and c-jun in myocytes after myocardial ... Expression of Proto-oncogenes and Gene Mutation of Sarcomeric Proteins in Patients With Hypertrophic Cardiomyopathy. Hisashi ... The ras proto-oncogene family encodes low-molecular-weight GTP-binding proteins, which serve as essential transducers of ... Expression of Proto-oncogenes and Gene Mutation of Sarcomeric Proteins in Patients With Hypertrophic Cardiomyopathy ...http://circres.ahajournals.org/content/83/6/594
Receptor Tyrosine Protein Kinase ERBB 4 (Tyrosine Kinase Type Cell Surface Receptor HER4 or Proto Oncogene Like Protein c ErbB...
Tyrosine Kinase Type Cell Surface Receptor HER4 or Proto Oncogene Like Protein c ErbB 4 or p180erbB4 or HER4 or ERBB4 or EC 2.7 ... Global Markets Directs, Receptor Tyrosine Protein Kinase ERBB 4 (... ... 111 Pages Report] Check for Discount on Receptor Tyrosine Protein Kinase ERBB 4 ( ... Jun 05, 2016: Puma Biotechnology Presents Positive Phase II Data at the 2016 ASCO Annual Meeting 96 May 18, 2016: Puma ...http://www.reportsnreports.com/reports/628278-receptor-tyrosine-protein-kinase-erbb-4-tyrosine-kinase-type-cell-surface-receptor-her4-or-proto-oncogene-like-protein-c-erbb-4-or-p180erbb4-or-her4-or-erbb4-or-ec-27101-pipeline-review-h1-2016.html
Tyrosine Protein Kinase Mer (Proto Oncogene c Mer or Receptor Tyrosine Kinase MerTK or MERTK or EC 220.127.116.11) - Pipeline Review,...
Tyrosine Protein Kinase Mer (Proto Oncogene c Mer or Receptor... ... Proto Oncogene c Mer or Receptor Tyrosine Kinase MerTK or MERTK ... 54 Pages Report] Check for Discount on Tyrosine Protein Kinase Mer ( ... Jun 08, 2010: Graham s Work In Pediatric Leukemia Genes Earns Him $1.3 Million In Grants To Test Targeted Drugs. Jun 08, 2010: ... Tyrosine Protein Kinase Mer (Proto Oncogene c Mer or Receptor Tyrosine Kinase MerTK or MERTK or EC 18.104.22.168) - Proto-oncogene ...http://www.reportsnreports.com/reports/1074270-tyrosine-protein-kinase-mer-proto-oncogene-c-mer-or-receptor-tyrosine-kinase-mertk-or-mertk-or-ec-27101-pipeline-review-h1-2017.html
IRS4 - Wikipedia
Koval, A P; Karas M; Zick Y; LeRoith D (Jun 1998). "Interplay of the proto-oncogene proteins CrkL and CrkII in insulin-like ... Koval AP, Karas M, Zick Y, LeRoith D (1998). "Interplay of the proto-oncogene proteins CrkL and CrkII in insulin-like growth ... The IRS4 protein is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation. IRS4 has been shown to ... Tyrosine-phosphorylated IRS4 protein has been shown to associate with cytoplasmic signalling molecules that contain SH2 domains ...https://en.wikipedia.org/wiki/IRS4
Serine/Threonine Protein Kinase A Raf (Proto Oncogene A Raf or Proto Oncogene Pks or ARAF or EC 22.214.171.124) - Pipeline Review, H2...
Proto Oncogene A Raf or Proto Oncogene Pks or ARAF or EC 126.96.36.199) - Pipeline Review, H2 2018 Serine/Threonine Protein - Market ... Jun 09, 2016: Basilea reports presentation of data on clinical oncology program BAL3833 at ASCO meeting. Apr 21, 2016: Basilea ... Serine/Threonine Protein Kinase A Raf (Proto Oncogene A Raf or Proto Oncogene Pks or ARAF or EC 188.8.131.52) - Pipeline Review, H2 ... Proto Oncogene A Raf or Proto Oncogene Pks or ARAF or EC 184.108.40.206) - Overview. Serine/Threonine Protein Kinase A Raf (Proto ...https://www.marketresearch.com/Global-Markets-Direct-v3480/Serine-Threonine-Protein-Kinase-Raf-11771275/