Critical involvement of RQCD1 in the EGFR-Akt pathway in mammary carcinogenesis. | Profiles RNS
Proto-Oncogene Proteins c-akt. * Reverse Transcriptase Polymerase Chain Reaction. * Signal Transduction ... Critical involvement of RQCD1 in the EGFR-Akt pathway in mammary carcinogenesis. Int J Oncol. 2010 Nov; 37(5):1085-93. ... Critical involvement of RQCD1 in the EGFR-Akt pathway in mammary carcinogenesis. ... Critical involvement of RQCD1 in the EGFR-Akt pathway in mammary carcinogenesis. ...
Recombinant Anti-AKT1 + AKT2 antibody [EPR17062] (ab182729) | Abcam
Protein kinase B beta antibody. *Proto oncogene c Akt antibody. *Proto-oncogene c-Akt antibody ... AKT2 is a putative oncogene and is a general protein kinase capable of phophorylating several known proteins. AKT2 is amplified ... Lane 2 : Human AKT2 fragment recombinant protein. Lane 3 : Human AKT3 fragment recombinant protein. Lysates/proteins at 0.02 µg ... Signal Transduction Protein Phosphorylation Ser / Thr Kinases PKB / AKT Share by email ...
Piceatannol, natural polyphenolic stilbene, inhibits adipogenesis via modulation of mitotic clonal expansion and insulin...
Protein Conformation, Proto-Oncogene Proteins c-akt, Receptor, Insulin, Signal Transduction, Stilbenes, Time Factors, ... Akt pathway in the early phase of adipogenesis. Moreover, we showed that piceatannol is an inhibitor of IR kinase activity and ...
Cells | Free Full-Text | Shared and Divergent Epigenetic Mechanisms in Cachexia and Sarcopenia
... leading to the suppression of several signaling proteins (p85α, IGF-1, and MYB Proto-Oncogene Like 2 (B-myb)) and consequently ... PI3K/AKT/mTOR) signaling pathway. Moreover, different research has highlighted the connection between myogenesis and protein ... Sca-1 overexpression has been shown to promote the expression of fibrosis-related genes such as proto-oncogene protein (Wnt) ... Indeed, it was predicted that miR-205 targets the MYC proto-oncogene, bHLH transcription factor (MYC), thus leading to the ...
Precision medicine for human cancers with Notch signaling dysregulation (Review)
... serine-protein kinase ATM; MAML, mastermind like protein; CSL, CBF1-suppressor of hairless-LAG1; BMI1, BMI1 proto-oncogene ... Ramakrishnan G, Davaakhuu G, Chung WC, Zhu H, Rana A, Filipovic A, Green AR, Atfi A, Pannuti A, Miele L and Tzivion G: AKT and ... inactive tyrosine-protein kinase 7; RET, proto-oncogene tyrosine-protein kinase receptor Ret; RON, macrophage-stimulating ... 1), such as BMI1 proto-oncogene polycomb ring finger (BMI1) (33,34), cyclin D1 (CCND1) (35,36), CD44 (37), CDKN1A (p21) (38,39 ...
Proto-Oncogene Proteins c-abl | Profiles RNS
Proto-Oncogene Proteins c-abl. *Proto-Oncogene Proteins c-akt. *Proto-Oncogene Proteins c-bcl-2 ... "Proto-Oncogene Proteins c-abl" by people in this website by year, and whether "Proto-Oncogene Proteins c-abl" was a major or ... "Proto-Oncogene Proteins c-abl" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH ( ... Proto-Oncogene Proteins c-abl*Proto-Oncogene Proteins c-abl. *Proto Oncogene Proteins c abl ...
Proto-Oncogene Proteins c-rel | Profiles RNS
Proto-Oncogene Proteins c-akt. *Proto-Oncogene Proteins c-bcl-2. *Proto-Oncogene Proteins c-bcl-6 ... "Proto-Oncogene Proteins c-rel" by people in this website by year, and whether "Proto-Oncogene Proteins c-rel" was a major or ... "Proto-Oncogene Proteins c-rel" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH ( ... Proto-Oncogene Proteins c-rel*Proto-Oncogene Proteins c-rel. *Proto Oncogene Proteins c rel ...
Proto-Oncogene Proteins c-abl | Profiles RNS
Proto-Oncogene Proteins c-abl. *Proto-Oncogene Proteins c-akt. *Proto-Oncogene Proteins c-bcl-2 ... "Proto-Oncogene Proteins c-abl" by people in this website by year, and whether "Proto-Oncogene Proteins c-abl" was a major or ... "Proto-Oncogene Proteins c-abl" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH ( ... Proto-Oncogene Proteins c-abl*Proto-Oncogene Proteins c-abl. *Proto Oncogene Proteins c abl ...
Reference Citation Analysis: Find an Article, Find a Category, Find a Journal, Find a Scholar
Proto-Oncogene Proteins c-akt/metabolism. *Carcinoma, Renal Cell/drug therapy. *Phosphatidylinositol 3-Kinases/metabolism ... The core genes were obtained via protein-protein interaction networks (PPI) analysis and molecular docking was examined, and ... The protein levels were characterized by Western Blot, and mRNA levels were evaluated by a real-time quantitative PCR detecting ... Immunohistochemistry and Western blot were used to test protein expression levels. H&E staining was used to explore the side ...
ARGUN AKCAKANAT | Profiles RNS
Proto-Oncogene Proteins c-akt * Phosphatidylinositol 3-Kinases * Breast Neoplasms Explore _. Co-Authors (53) ... Phase II trial of AKT inhibitor MK-2206 in patients with advanced breast cancer who have tumors with PIK3CA or AKT mutations, ... Comparison of Akt/mTOR signaling in primary breast tumors and matched distant metastases. Cancer. 2008 Jun; 112(11):2352-8. ... Targeting the PI3-kinase/Akt/mTOR signaling pathway. Surg Oncol Clin N Am. 2013 Oct; 22(4):641-64. PMID: 24012393; PMCID: ...
Leukemia | Profiles RNS
Proline-Directed Protein Kinases | Profiles RNS
Proto-Oncogene Proteins c-akt. *Proto-Oncogene Proteins c-bcr. *Proto-Oncogene Proteins c-pim-1 ... Protein-Serine-Threonine Kinases [D08.811.913.696.620.682.700]. *Proline-Directed Protein Kinases [D08.811.913.696.620.682. ... A subclass of protein serine-threonine kinases that phosphorylate proteins on a SERINE or THREONINE residue that is immediately ... "Proline-Directed Protein Kinases" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH ( ...
NF-kappa B - metabolism
Proto-oncogene proteins c-akt - metabolism ; Signal transduction - drug effects ; Transcriptional activation - drug effects ; ... Oncogene protein v-akt - metabolism ; Phosphatidylinositol 3-kinases - antagonists & inhibitors ; Phosphatidylinositol 3- ... Jagged-1 protein - biosynthesis ; Jagged-1 protein - genetics ; Jagged-1 protein - metabolism ; Jurkat cells ; Leukemia- ... Mitogen-activated protein kinases - metabolism ; NF-kappa B - metabolism ; Skin - cytology ; Son of sevenless protein, ...
Glucose transporter type 1 - metabolism
Proto-oncogene proteins c-akt - metabolism ; Rats ; Rats, wistar. Charakt. formalna: Zagraniczny artyku Charakt. merytoryczna: ... bcl-X protein - metabolism ; bcl-2-associated X protein - metabolism ; Proto-oncogene proteins c-bcl-2 - metabolism ; ... Proto-oncogene proteins c-akt - metabolism ; Rats ; Rats, Wistar ; Stearoyl-CoA desaturase - metabolism ; Sterol regulatory ... bcl-X protein - metabolism ; bcl-X protein - biosynthesis ; bcl-2-associated X protein - metabolism ; bcl-2-associated X ...
Akt mediated phosphorylation of LARP6; critical step in biosynthesis of type I collagen. | DigiNole
Proto-Oncogene Proteins c-akt/metabolism. Ribonucleoproteins/chemistry. Ribonucleoproteins/metabolism. Sequence Homology, Amino ... suggesting that PI3K/Akt pathway targets S451 and we have identified Akt as the responsible kinase. Overexpression of S451A ... Akt inhibitor, GSK-2141795, which is in clinical trials for treatment of solid tumors, reduced collagen production by human ... Inhibition of PI3K/Akt pathway reduced the phosphorylation of LARP6, but had no effect on the S451A mutant, ...
Cellular mechanisms of cardiomyopathy | CU Experts | CU Boulder
Zn2+ influx activates ERK and Akt signaling pathways | CU Experts | CU Boulder
Search | Global Index Medicus
Recombinant Proteins (2) Biomarkers (2) Proto-Oncogene Proteins c-akt (2) Metabolism (2) ... Western blot assay was used to detect the expressions of B-cell lympho ma-2(Bcl-2),Bcl-2 associated X protein (Bax),caspase-3, ... Western blotting was used to detect the expression levels of apoptosis-related proteins in cells of control group and 1/2 IC 50 ... the protein expressions of Bax ,Cyt-C and cleaved-caspase- 3 were upregulated significantly , while those of Bcl- 2,caspase-3, ...
AKT1 Polyclonal Antibody (PA5-96351)
Protein kinase B; Protein kinase B alpha; protein kinase B-alpha; Proto-oncogene c-Akt; rac protein kinase alpha; RAC protein ... thymoma viral proto-oncogene 1; v-akt murine thymoma viral oncogene homolog 1; v-akt murine thymoma viral oncogene-like protein ... Protein Aliases: AKT1 kinase; AKT1m; Akt1m protein; C-AKT; CAKT; murine thymoma viral (v-akt) oncogene homolog 1; PKB; PKB ... protein kinase activity protein serine/threonine kinase activity protein serine/threonine/tyrosine kinase activity protein ...
WikiGenes - Metabolism
Proto-oncogene c-fos expression in growth regions of fetal bone and mesodermal web tissue. Dony, C., Gruss, P. Nature (1987) [ ... Mechanisms and consequences of activation of protein kinase B/Akt. Downward, J. Curr. Opin. Cell Biol. (1998) [Pubmed] ... The phylogenic conservation of the proto-oncogene c-fos suggests that this gene product is required for normal metabolic ... Escherichia coli single-stranded DNA-binding protein: multiple DNA-binding modes and cooperativities. Lohman, T.M., Ferrari, M. ...
Search | Global Index Medicus
Proto-Oncogene Proteins c-akt/metabolism , Signal Transduction , Sphingosine/analogs & derivatives , Stem Cells ... Tau protein levels decreased in the soluble and insoluble fractions when Hsp70 was overexpressed in HEK293T cells. Transfection ... Most importantly, an AKT activator completely abrogated the S1P-mediated downregulation of osteoblastic markers and partially ... Interestingly, a diurnal oscillation was detected in the heat shock 70 kDa protein 1A (Hsp70) chaperone that was in-phase with ...
DeCS 2017 - July 04, 2017 version
c-akt Proto-Oncogene Protein use Proto-Oncogene Proteins c-akt c-akt, Proto-Oncogene Proteins use Proto-Oncogene Proteins c-akt ... c-akt1, Proto-Oncogene Proteins use Proto-Oncogene Proteins c-akt c-akt2, Proto-Oncogene Proteins use Proto-Oncogene Proteins c ... c-bcr Proto-Oncogene Proteins use Proto-Oncogene Proteins c-bcr c-bcr, Proto-Oncogene Protein use Proto-Oncogene Proteins c-bcr ... c-crk Proto-Oncogene Proteins use Proto-Oncogene Proteins c-crk c-crk, Proto-Oncogene Protein use Proto-Oncogene Proteins c-crk ...
DeCS 2018 - July 31, 2018 version
c-akt Proto-Oncogene Protein use Proto-Oncogene Proteins c-akt c-akt, Proto-Oncogene Proteins use Proto-Oncogene Proteins c-akt ... c-akt1, Proto-Oncogene Proteins use Proto-Oncogene Proteins c-akt c-akt2, Proto-Oncogene Proteins use Proto-Oncogene Proteins c ... c-bcr Proto-Oncogene Proteins use Proto-Oncogene Proteins c-bcr c-bcr, Proto-Oncogene Protein use Proto-Oncogene Proteins c-bcr ... c-crk Proto-Oncogene Proteins use Proto-Oncogene Proteins c-crk c-crk, Proto-Oncogene Protein use Proto-Oncogene Proteins c-crk ...
DeCS 2016 - June 12, 2016 version
c-akt Proto-Oncogene Protein use Proto-Oncogene Proteins c-akt c-akt, Proto-Oncogene Proteins use Proto-Oncogene Proteins c-akt ... c-akt1, Proto-Oncogene Proteins use Proto-Oncogene Proteins c-akt c-akt2, Proto-Oncogene Proteins use Proto-Oncogene Proteins c ... c-bcr Proto-Oncogene Proteins use Proto-Oncogene Proteins c-bcr c-bcr, Proto-Oncogene Protein use Proto-Oncogene Proteins c-bcr ... c-crk Proto-Oncogene Proteins use Proto-Oncogene Proteins c-crk c-crk, Proto-Oncogene Protein use Proto-Oncogene Proteins c-crk ...
DeCS 2017 - December 21, 2017 version
c-akt Proto-Oncogene Protein use Proto-Oncogene Proteins c-akt c-akt, Proto-Oncogene Proteins use Proto-Oncogene Proteins c-akt ... c-akt1, Proto-Oncogene Proteins use Proto-Oncogene Proteins c-akt c-akt2, Proto-Oncogene Proteins use Proto-Oncogene Proteins c ... c-bcr Proto-Oncogene Proteins use Proto-Oncogene Proteins c-bcr c-bcr, Proto-Oncogene Protein use Proto-Oncogene Proteins c-bcr ... c-crk Proto-Oncogene Proteins use Proto-Oncogene Proteins c-crk c-crk, Proto-Oncogene Protein use Proto-Oncogene Proteins c-crk ...
Frontiers | When RON MET TAM in Mesothelioma: All Druggable for One, and One Drug for All?
... also known as Macrophage Stimulating Protein (MSP) or Hepatocyte Growth Factor-Like Protein (HGFL). In this study, we ... also known as Macrophage Stimulating Protein (MSP) or Hepatocyte Growth Factor-Like Protein (HGFL). In this study, we ... MST1R (RON) is a trans-membrane receptor tyrosine kinase (RTK), which is part of the c-MET proto-oncogene family. The only ... MST1R (RON) is a trans-membrane receptor tyrosine kinase (RTK), which is part of the c-MET proto-oncogene family. The only ...
WikiGenes - Hspa5 - heat shock protein 5
Reprogramming of gene expression in postischemic rat liver: induction of proto-oncogenes and hsp 70 gene family. Schiaffonati, ... A proteomic screen identified stress-induced chaperone proteins as targets of Akt phosphorylation in mesangial cells. Barati, M ... GRP78-binding protein regulates cAMP-induced glial fibrillary acidic protein expression in rat C6 glioblastoma cells. Oh-hashi ... Induction of glucose regulated protein (grp78) and inducible heat shock protein (hsp70) mRNAs in rat brain after kainic acid ...
EGFRv3 Polyclonal Antibody - Bioss
Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1; EGFR. ... Activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs ... Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor ... The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. ...
Mucin-4 | Profiles RNS
Protein Tyrosine Phosphatases, Non-Receptor. *Proto-Oncogene Proteins c-akt. *Proto-Oncogene Proteins c-fyn ... Mucin-4 may play a role in regulating cellular adhesion and in cell surface signaling from the ERBB-2 RECEPTOR PROTEIN-TYROSINE ... The alpha and beta chains result from the proteolytic cleavage of a precursor protein. ...
How PD-1 abrogates the anti-tumor immune response | Cancer Biology
The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), ... PD-1 does so by blocking PI3K/Akt and Ras/MEK/Erk, pathways that induce SKP2 (Figure 5). Akt controls Skp2 stability and the ... Cooperation between ERK and Skp2 has also been found in human breast cancer whereby synergistic activity of the two oncogenes ... this gene is established as a protooncogene causally involved in the pathogenesis of lymphomas. ...