Activation of AKT is associated with metastasis of nasopharyngeal carcinoma. - PubMed - NCBI
Proto-Oncogene Proteins c-akt/biosynthesis*. *Proto-Oncogene Proteins c-akt/genetics ... The knockdown of AKT in SUNE-1 cells markedly increased apoptotic cell rate. Radiotherapy can increase the levels of AKT in NPC ... Activation of AKT is associated with metastasis of nasopharyngeal carcinoma.. Liu Y1, Chen LH, Yuan YW, Li QS, Sun AM, Guan J. ... The levels of AKT in SUNE-1 cells were also assessed. The frequency of apoptotic SUNE-1 cells was evaluated by flow cytometry. ...https://www.ncbi.nlm.nih.gov/pubmed/22116667?dopt=Abstract
RNA Therapeutics - & related info | Mendeley
RNA modifications impact numerous cellular processes such as pre-mRNA splicing and protein synthesis. The elucidation of the ... Proto-Oncogene Proteins c-akt. *Proto-Oncogene Proteins c-akt: metabolism. *R Medicine (General) ... RNA modifications impact numerous cellular processes such as pre-mRNA splicing and protein synthesis. The elucidation of the ...https://www.mendeley.com/research-papers/rna-therapeutics-1/
AKT/PKB signaling: navigating downstream. - PubMed - NCBI
Proto-Oncogene Proteins c-akt/genetics. *Proto-Oncogene Proteins c-akt/metabolism* ... The serine/threonine kinase Akt, also known as protein kinase B (PKB), is a central node in cell signaling downstream of growth ... Akt-mediated phosphorylation of these proteins leads to their activation (arrows) or inhibition (blocking arrows). Regulation ... AKT and PDK1 bind to PIP3 at the plasma membrane, and PDK1 phosphorylates the activation loop of AKT at T308. RTK signaling ...https://www.ncbi.nlm.nih.gov/pubmed/17604717?dopt=Abstract
Overexpression of Akt inhibits NGF-induced growth arrest and neuronal differentiation of PC12 cells.
PC12 cells ectopically expressing wild-type or dominant-inhibitory forms of Akt were analyzed. NGF-induced neurite outgrowth ... To investigate the role of Akt in nerve growth factor (NGF)-induced neuronal differentiation, ... Protein-Serine-Threonine Kinases*. Proto-Oncogene Proteins / genetics, physiology*. Proto-Oncogene Proteins c-akt. Rats. ... EC 184.108.40.206/Protein-Serine-Threonine Kinases; EC 220.127.116.11/Proto-Oncogene Proteins c-akt; EC 18.104.22.168/CDC2 Protein Kinase ...http://www.biomedsearch.com/nih/Overexpression-Akt-inhibits-NGF-induced/11112692.html
RNA interference demonstrates a novel role for integrin-linked kinase as a determinant of pancreatic adenocarcinoma cell...
... facilitates signal transduction between extracellular events and important intracellular survival pathways involving protein ... kinase B/Akt. We examined the role of ILK in determining pancreatic adenocarcinoma cellular chem ... Proto-Oncogene Proteins / metabolism. Proto-Oncogene Proteins c-akt. RNA Interference*. RNA, Small Interfering / genetics, ... EC 22.214.171.124/AKT1 protein, human; EC 126.96.36.199/Protein-Serine-Threonine Kinases; EC 188.8.131.52/Proto-Oncogene Proteins c-akt; EC ...http://www.biomedsearch.com/nih/RNA-interference-demonstrates-novel-role/15867245.html
Endothelial-specific CYP4A2 overexpression leads to renal injury and hypertension via increased production of 20-HETE. |...
AMP-Activated Protein Kinases. *Proto-Oncogene Proteins c-akt. *Acetylcholine. Topics. *AMP-Activated Protein Kinases ( ... HET0016 treatment decreased oxidative stress and increased the phosphorylated state of key proteins that regulate endothelial ... function, including eNOS, AKT, and AMPK. Collectively, these findings demonstrate that augmentation of vascular endothelial 20- ...http://www.curehunter.com/public/pubmed19675180.do
MEDLINE - Resultado p gina 1
Proto-Oncogene Proteins c-akt); EC 184.108.40.206 (AMP-Activated Protein Kinases); YAS4TBQ4OQ (plumbagin). ... Prote nas Proto-Oncog nicas c-akt/metabolismo. Transdu o de Sinais/gen tica. Serina-Treonina Quinases TOR/metabolismo. ... Plumbagin inhibits the growth of cancer cells mainly through the modulation of the signals of PI3K/Akt/mTOR, AMPK, Ras, and so ... OPN-induced the phosphorylation of FAK and AKT was impaired without affecting their total forms by plumbagin treatment. OPN ...http://bases.bireme.br/cgi-bin/wxislind.exe/iah/online/?IsisScript=iah/iah.xis&nextAction=lnk&base=MEDLINE&lang=p&format=detailed.pft&indexSearch=EX&exprSearch=B01.650.940.800.575.9220.127.116.110.937
MEDLINE - Resultado p gina 1
Proto-Oncogene Proteins c-akt); EC 18.104.22.168 (Mitogen-Activated Protein Kinase 3); EC 22.214.171.124 (Phosphoenolpyruvate ... Prote nas Proto-Oncog nicas c-akt/metabolismo. [Mh] Termos MeSH secund rio:. Animais. Carcinoma Hepatocelular/metabolismo. ... induce phosphorylation of Akt and suppress Pck1 expression in hepatoma cells.. [So] Source:. Biochem Cell Biol;94(3):270-8, ... This was associated with the phosphorylation of Akt and Erk1/2 in a time-dependent manner. Further analysis of the purified ...http://bases.bireme.br/cgi-bin/wxislind.exe/iah/online/?IsisScript=iah/iah.xis&nextAction=lnk&base=MEDLINE&lang=p&format=detailed.pft&indexSearch=EX&exprSearch=B01.650.940.800.575.912.250.456
Expression of CDC47/MCM7 (A), Akt (B) and Phospho-Akt ( | Open-i
... and Phospho-Akt (C) in response to 17β-estradiol (E2) in rat endometrium. Animals were ovariectomized for at least 10 day ... Protein Processing, Post-Translational/physiology*. *Protein-Serine-Threonine Kinases/metabolism*. *Proto-Oncogene Proteins/ ... Akt protein expression was maximal at estrus. IHC revealed that Akt expression was high in both stromal and epithelial cells at ... Akt protein expression was maximal at estrus. IHC revealed that Akt expression was high in both stromal and epithelial cells at ...https://openi.nlm.nih.gov/detailedresult.php?img=PMC161822_1477-7827-1-47-6&req=4
TNO Repository search for: subject:'Cell Membrane'
Protein Binding · Protein-Serine-Threonine Kinases · Protein-Tyrosine Kinases · Proto-Oncogene Proteins c-akt · Pyridines · ... Protein-Serine-Threonine Kinases, EC 126.96.36.199; Protein-Tyrosine Kinases, EC 188.8.131.52; Proto-Oncogene Proteins c-akt, EC 2.7. ... Fungal protein · KRE6 protein, S cerevisiae · Membrane protein · Multienzyme complex · Saccharomyces cerevisiae protein · SKN1 ... Nutrition · Bacterial protein · Binding protein · Collagen binding s protein · Unclassified drug · Bacterium adherence · Gene ...https://repository.tudelft.nl/search/tno/?q=subject%3A%22Cell%20Membrane%22
A Schematic Representation of the Potential for Novel M | Open-i
Protein Kinases/physiology. *Proto-Oncogene Proteins c-akt/physiology. *Receptor, Epidermal Growth Factor/antagonists & ... or activate oncogenes such as MDM2 and CDKs 4 and 6; alterations in EGFR are less common or absent... Frequently, loss of PTEN ... or activate oncogenes such as MDM2 and CDKs 4 and 6; alterations in EGFR are less common or absent... Frequently, loss of PTEN ... and feedback loop inhibition of AKT (see Figure 4A in ). In seven of 14 patients (50%), suppression of mTOR correlated ...https://openi.nlm.nih.gov/detailedresult.php?img=PMC2211557_pmed.0050021.g003&req=4
Epidermal growth factor receptor, c-erbB2 and c-erbB3 receptor interaction, and related cell cycle kinetics of SK-BR-3 and...
Proto-Oncogene Proteins/metabolism. MESH. Proto-Oncogene Proteins c-akt. MESH. Receptor, Epidermal Growth Factor/metabolism. ... However, only SK-BR-3 cells showed a constitutive activation of both protein kinase B (PKB)/Akt and MAPK signaling pathways. ... In contrast, the concurrent activation of MAPK and PKB/Akt by EGF treatment led to an inhibition of proliferation in SK-BR-3 ... Growth factor treatment caused an amplified PKB/Akt activation in this cell line. The induction of EGFR/c-erbB2 complexes in ...https://epub.uni-regensburg.de/15396/
adenoma of alveoli 2005:2010[pubdate] *count=100 - BioMedLib™ search engine
Proto-Oncogene Proteins / metabolism. Proto-Oncogene Proteins c-akt. Ribosomal Protein S6 Kinases / biosynthesis. TOR Serine- ... mTOR protein, mouse; EC 184.108.40.206 / Protein-Serine-Threonine Kinases; EC 220.127.116.11 / Proto-Oncogene Proteins c-akt; EC 18.104.22.168 ... Proto-Oncogene Proteins; 624KN6GM2T / temsirolimus; EC 2.7.- / Protein Kinases; EC 22.214.171.124 / MTOR protein, human; EC 126.96.36.199 / ... Chemical-registry-number] 0 / BNip3 protein, mouse; 0 / DNA-Binding Proteins; 0 / Membrane Proteins; 0 / Mitochondrial Proteins ...http://www.bmlsearch.com/?kwr=adenoma+of+alveoli+2005:2010%5Bpubdate%5D&cxts=100&stmp=b0
acinic cell tumor salivary gland 2005:2010 - BioMedLib™ search engine
Proto-Oncogene Proteins c-akt. Salivary Ducts / pathology. Signal Transduction. *MedlinePlus Health Information. consumer ... Proto-Oncogene Proteins c-kit / analysis. Time Factors. Translocation, Genetic. Ubiquitin-Protein Ligases / analysis. Young ... KRT7 protein, human; 0 / Keratin-5; 0 / Keratin-7; EC 188.8.131.52 / Proto-Oncogene Proteins c-kit; EC 184.108.40.206 / MIB1 ligase, ... Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / ETV6-NTRK3 fusion protein, human; 0 / Oncogene Proteins, Fusion ...http://bmlsearch.com/?kwr=acinic%20cell%20tumor%20salivary%20gland%202005:2010
embryonal carcinoma of testis diagnosis drug therapy 2000:2010[pubdate] *count=100 - BioMedLib™ search engine
Proto-Oncogene Proteins c-akt; EC 220.127.116.11 / CDK2 protein, human; EC 18.104.22.168 / Cyclin-Dependent Kinase 2; Q20Q21Q62J / ... Chemical-registry-number] 0 / Antineoplastic Agents; 0 / MDM4 protein, human; 0 / Nuclear Proteins; 0 / Proto-Oncogene Proteins ... EC 3.4.- / Endopeptidases; EC 3.4.- / USP2 protein, human; EC 22.214.171.124 / MDM2 protein, human; EC 126.96.36.199 / Proto-Oncogene ... Neoplasm Proteins / biosynthesis. Neoplasm Proteins / genetics. Prodrugs / therapeutic use. Prostatic Neoplasms / pathology. ...http://www.bmlsearch.com/?kwr=embryonal+carcinoma+of+testis+diagnosis+drug+therapy+2000:2010%5Bpubdate%5D&cxts=100&stmp=b1
Tumor Suppressor Proteins - Proteins, Tumor Suppressor Summary Report | CureHunter
Proteins that are normally involved in holding cellular growth in check. Deficiencies or abnormalities in these proteins may ... Proto-Oncogene Proteins c-akt (Protein Kinase B) 8. clinoptilolite 9. Oncogene Proteins (Oncogene Protein) ... Amino Acids, Peptides, and Proteins*Proteins: 90489*Neoplasm Proteins: 2*Tumor Suppressor Proteins: 254*Retinoblastoma Protein ... Proteins, Tumor Suppressor; Proteins, Growth Suppressor; Proteins, Metastasis Suppressor; Growth Suppressor Proteins; ...http://www.curehunter.com/public/keywordSummaryD025521-Tumor-Suppressor-Proteins-Proteins--Tumor-Suppressor.do
ZFIN Publication: Blackburn et al., 2014
Proto-Oncogene Proteins c-akt/antagonists & inhibitors. *Proto-Oncogene Proteins c-akt/metabolism* ... Akt pathway activation was acquired in a subset of these evolved clones, which increased the number of leukemia-propagating ... Clonal evolution enhances leukemia-propagating cell frequency in T cell acute lymphoblastic leukemia through Akt/mTORC1 pathway ... which was reversed by combined treatment with an Akt inhibitor. Thus, T-ALL clones spontaneously and continuously evolve to ...http://zfin.org/ZDB-PUB-140513-379
green tea - BioMedLib™ search engine
... bcl-2-Associated X Protein; 17885-08-4 / Phosphoserine; EC 188.8.131.52 / Proto-Oncogene Proteins c-akt; EC 184.108.40.206 / Histone ... Cites] Oncogene. 2003 Jul 31;22(31):4851-9 [12894226.001]. *[Cites] Prostate Cancer Prostatic Dis. 2003;6(4):281-5 [ ... Amino Acid, Peptide, or Protein. A220.127.116.11.1.8. Carbohydrate. A18.104.22.168.1.9. Lipid. A22.214.171.124.1.9.1. Steroid. A126.96.36.199.1.9.2. ... Chemical-registry-number] 0 / Anticarcinogenic Agents; 0 / Codon; 0 / Tea; 0 / Tumor Suppressor Protein p53 ...http://bmlreview.com/?kwr=green+tea&smntc=neoplastic+process&kwr=&ck=&cxts=10&fntszff=100&hghlght=maroon&srtrdr=relevance&annttn=none&pdthm=2010&hqryhstry=5062b3f288e4d101&pgwdth=100&mld=&wft=wims&b4s=962115769
Welcome to LibAge, the ageing reference resource
Entries tagged Proto-Oncogene Proteins c-akt (825). Sort:. Number of citations. Author. Title. Year. PubMed ID. ... 2001) "Protein kinase B (PKB/Akt)--a key regulator of glucose transport?" FEBS Lett. 492(3):199-203 (PubMed) ... 2002) "Akt induces enhanced myocardial contractility and cell size in vivo in transgenic mice." Proc. Natl. Acad. Sci. U.S.A. ... 1998) "The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: linkage of double-strand break repair to the cellular ...http://libage.ageing-map.org/entries/tags/91/
ZFIN Publication: Ju et al., 2009
Proto-Oncogene Proteins c-akt/genetics. *Proto-Oncogene Proteins c-akt/metabolism* ... indicating activation of the PI3K-AKT pathway. These results suggest that co-activation of the hedgehog and AKT pathways ... Co-activation of hedgehog and AKT pathways promote tumorigenesis in zebrafish. Ju, B., Spitsbergen, J., Eden, C.J., Taylor, M.R ... Ju, B., Spitsbergen, J., Eden, C.J., Taylor, M.R., and Chen, W. (2009) Co-activation of hedgehog and AKT pathways promote ...http://zfin.org/ZDB-PUB-090629-30
Cerebral Hemorrhage, Traumatic; Brain Hemorrhage, Cerebral, Traumatic; Cerebral Hematoma, Traumatic; Intracerebral Hemorrhage,...
Proto-Oncogene Proteins c-akt. 1. + +. 373. Nicergoline. 1. + +. 374. Muscimol. 1. + +. ...https://lookfordiagnosis.com/results.php?symptoms=Cerebral+Hemorrhage%2C+Traumatic%3B%20Brain%20Hemorrhage%2C%20Cerebral%2C%20Traumatic%3B%20Cerebral%20Hematoma%2C%20Traumatic%3B%20Intracerebral%20Hemorrhage%2C%20Traumatic&lang=1&parent=%2F&mode=F&therapy_ap=1
"Ligation of TLR5 promotes myeloid cell infiltration and differentiatio" by Seung-Jae Kim, Zhenlong Chen et al.
Proto-Oncogene Proteins c-akt; RANK Ligand; Receptor Activator of Nuclear Factor-kappa B; Synovial Fluid; Toll-Like Receptor 5 ... JNK Mitogen-Activated Protein Kinases; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Middle Aged; Monocytes; Myeloid ...https://escholarship.umassmed.edu/rheumatology_pubs/49/
Transfusion effects on cardiomyocyte growth and proliferation in fetal sheep after chronic anemia<...
Mitogen-Activated Protein Kinase 8 Proto-Oncogene Proteins c-akt Mitogen-Activated Protein Kinase Kinases ... Protein levels of mitogen-activated protein kinases and protein kinase B were similar between controls and their respective ... Protein levels of mitogen-activated protein kinases and protein kinase B were similar between controls and their respective ... Protein levels of mitogen-activated protein kinases and protein kinase B were similar between controls and their respective ...https://ohsu.pure.elsevier.com/en/publications/transfusion-effects-on-cardiomyocyte-growth-and-proliferation-in--2
"Pathological axonal death through a MAPK cascade that triggers a local" by Jing Yang, Zhuhao Wu et al.
The adaptor protein Sarm1 is required for activation of this MAPK cascade, and this Sarm1-MAPK pathway disrupts axonal energy ... Further, MKK4, a key component in the Sarm1-MAPK pathway, is antagonized by AKT signaling, which modulates the degenerative ... The protective cytoNmnat1/Wld(s) protein inhibits activation of this MAPK cascade. ... Using traumatic injury as a model, we systematically investigate mitogen-activated protein kinase (MAPK) families and delineate ...https://escholarship.umassmed.edu/davis/13/
Characterization of FOXO1,3 and 4 transcription factors in ovaries of fetal, prepubertal and adult rhesus macaques<...
Proto-Oncogene Proteins c-akt 1-Phosphatidylinositol 4-Kinase Ovarian Follicle Granulosa Cells ... In the current study, protein localization of FOXO1, 3, and 4 as well as their upstream regulator, AKT/p-AKT, was examined in ... In the current study, protein localization of FOXO1, 3, and 4 as well as their upstream regulator, AKT/p-AKT, was examined in ... In the current study, protein localization of FOXO1, 3, and 4 as well as their upstream regulator, AKT/p-AKT, was examined in ...https://ohsu.pure.elsevier.com/en/publications/characterization-of-foxo13-and-4-transcription-factors-in-ovaries