ETS2 | Cancer Genetics Web
Proto-Oncogene Protein c-ets-1. *Transcriptional Regulator ERG. *Signal Transduction. *Leukaemia ... ETS-2 and ETS variant gene‑4 (ETV‑4), in PCa as a proof of principle. Using western blot analysis, we show that ERG, ETS-1, ETS ... The encoded protein is also a protooncogene and shown to be involved in regulation of telomerase. A pseudogene of this gene is ... V-ets erythroblastosis virus E26 oncogene homolog 2 (ETS2) and Single Minded 2 (SIM2) are two such TFs that regulate several ...http://www.cancerindex.org/geneweb/ETS2.htm
ZFIN Publication: Zhu et al., 2005
Proto-Oncogene Protein c-ets-1/biosynthesis. *Transcription Factors. *Zebrafish/embryology*. *Zebrafish/genetics ... This element contains critical ETS-binding sites conserved between zebrafish and pufferfish. Furthermore, we show that ets1 is ... we generated stable transgenic zebrafish that express green fluorescent protein (EGFP) or DsRed under the control of an lmo2 ...https://zfin.org/ZDB-PUB-050518-14
"Co-stimulation of the bone-related Runx2 P1 promoter in mesenchymal ce" by Ying Zhang, Mohammad Q. Hassan et al.
Taken together, our data suggest that basal Runx2 gene transcription is regulated by dynamic interactions between SP1 and ETS- ... both proteins are transiently co-expressed when Runx2 expression is enhanced. ... and ETS-like factors (e.g. ETS1 and ELK1). Forced expression of SP1 increases Runx2 P1 promoter activity through the Y-repeats ... reveal that Y-repeat binds at least two different classes of transcription factors related to GC box binding proteins (e.g. SP1 ...https://escholarship.umassmed.edu/oapubs/2147/
ETS1 Gene - GeneCards | ETS1 Protein | ETS1 Antibody
Protein Coding), ETS Proto-Oncogene 1, Transcription Factor, including: function, proteins, disorders, pathways, orthologs, and ... Protein details for ETS1 Gene (UniProtKB/Swiss-Prot). Protein Symbol:. P14921-ETS1_HUMAN. Recommended name:. Protein C-ets-1 ... ETS1 (ETS Proto-Oncogene 1, Transcription Factor) is a Protein Coding gene. Diseases associated with ETS1 include Jacobsen ... Avian Erythroblastosis Virus E26 (V-Ets) Oncogene Homolog-1 2 3 * V-Ets Avian Erythroblastosis Virus E26 Oncogene Homolog 1 2 3 ...http://www.genecards.org/cgi-bin/carddisp.pl?id_type=entrezgene&id=2113
Gene Module Based Regulator Inference Identifying miR-139 as a Tumor Suppressor in Colorectal Cancer
Proto-Oncogene Protein c-ets-1. Cancer cells--Proliferation. Abstract. : Colorectal cancer is one of the most commonly ... By integrating gene differential expression and co-expression information with a protein-protein interaction network, the ... A known oncogene ETS1, a key transcription factor in the gene module, was experimentally verified as a novel target of miR-139 ...http://libtreasures.utdallas.edu/xmlui/handle/10735.1/4229
Ets1 - Protein C-ets-1 - Mus musculus (Mouse) - Ets1 gene & protein
Proto-oncogene. ,p>This section describes post-translational modifications (PTMs) and/or processing events.,p>,a href='/help/ ... PROSITE; a protein domain and family database. More...PROSITEi. View protein in PROSITE. PS00345 ETS_DOMAIN_1, 1 hit. PS00346 ... View protein in InterPro. IPR000418 Ets_dom. IPR003118 Pointed_dom. IPR013761 SAM/pointed_sf. IPR016311 Transform_prot_C-ets. ... View protein in InterPro. IPR000418 Ets_dom. IPR003118 Pointed_dom. IPR013761 SAM/pointed_sf. IPR016311 Transform_prot_C-ets. ...https://www.uniprot.org/uniprot/P27577
The transcription factor ETS-1: its role in tumour development and strategies for its inhibition. - Nuffield Department of...
With regard to the involvement of some ETS transcription factors, especially Ets-1, in malignant transformation and tumour ... the prototype of the ETS family of transcription factors. ETS family members play important roles in development, ... Several ets genes are rearranged in human leukaemia, Ewing tumours and prostate cancer to produce chimeric oncoproteins. ... Most of them are downstream nuclear targets of Ras-MAP kinase signalling and the deregulation of ets genes results in malignant ...https://www.ndorms.ox.ac.uk/publications/272425
Academic Dissertations;SPDEF protein human;Breast Neoplasms;Proto-Oncogene Protein c-ets-1 ... Academic Dissertations;Academic Dissertations--South Carolina;Proto-Oncogene Proteins c-akt;Vascular Endothelial Growth Factors ... Role of the ETS transcription factor PDEF in breast development and cancer ...http://digital.library.musc.edu/cdm/search/searchterm/Originally/mode/all/page/2
Academic Dissertations;SPDEF protein human;Breast Neoplasms;Proto-Oncogene Protein c-ets-1 ... Oncogene Proteins, Viral;Ceramides;DNA-Binding Proteins;Repressor Proteins;Cell Cycle Checkpoints;Apoptosis;DNA Damage;Mutation ... p38 Mitogen-Activated Protein Kinases;Tumor Necrosis Factor-alpha;Extracellular Signal-Regulated MAP Kinases;Interferon-gamma; ... Role of the ETS transcription factor PDEF in breast development and cancer ...http://digital.library.musc.edu/cdm/search/searchterm/activate/mode/all/order/creato
Expression and function of transcription factor cMyb during cranial neural crest development. - Radcliffe Department of Medicine
Proto-Oncogene Protein c-ets-1, Transcription Factors, Twist-Related Protein 1 ... Gene regulatory network, Neural crest, Neural plate border, Transcription factor, cMyb, Animals, Avian Proteins, Chick Embryo, ...https://www.rdm.ox.ac.uk/publications/449222
Localization and Modulation of the DNA-binding Activity of the Human c-ets-1 Protooncogene | Cancer Research
... ets fusion protein that is located in the nucleus of the transformed cells. The cellular homologue of v-ets (c-ets-1) is highly ... indicating that these differences may be partly responsible for the activation of the ets oncogene. ... ets gene products are DNA-binding proteins and their DNA-binding activity is located in the carboxy terminal (46 amino acid ... ets. The viral protein responsible for transformation is a gag-myb- ...http://cancerres.aacrjournals.org/content/50/16/5013.long
Yin yang 1 regulates the expression of snail through a distal enhancer. - PubMed - NCBI
ETS1 protein, human. *Proto-Oncogene Protein c-ets-1. *SOX Transcription Factors ... Proteins specifically binding these sequences were detected by electrophoretic mobility shift assay. The Ets/YY1 binding ... Sequence-specific binding of proteins to the Ets/YY1 site in vitro ... A mutant DNA affinity column consisting of concatamerized Ets/YY1 EMSA probe bearing a mutation in the Ets/YY1 site was ...https://www.ncbi.nlm.nih.gov/pubmed/19208738
Expression analysis of ETS1 gene in peripheral blood mononuclear cells with systemic lupus erythematosus by real-time reverse...
Proto-Oncogene Protein c-ets-1/genetics*. *Reverse Transcriptase Polymerase Chain Reaction ...https://www.ncbi.nlm.nih.gov/pubmed/20819682?dopt=Abstract
Rapamycin-induced inhibition of HTLV-I LTR activity is rescued by c-Myb | Retrovirology | Full Text
Ets and c-Myb, are implicated in the rapamycin-sensitivity of the HTLV-I LTR. An in vitro analysis of the role of SRE- and NF- ... Rohwer F, Todd S, McGuire KL: The effect of IL-2 treatment on transcriptional attenuation in proto-oncogenes pim-1 and c-myb in ... Beimling P, Moelling K: Direct interaction of CREB protein with 21 bp Tax-response elements of HTLV-I LTR. Oncogene. 1992, 7: ... a member of the Ets oncogene family, and ATF2/CREBP1. We have highlighted the reduction in available c-Myb as being a potential ...https://retrovirology.biomedcentral.com/articles/10.1186/1742-4690-4-24
Activation of the HIV-1 enhancer by the LEF-1 HMG protein on nucleosome-assembled DNA in vitro. - Sheridan P. L.
Proto-Oncogene Proteins/metabolism ; Proto-Oncogene Proteins c-ets ; Recombinant Proteins/metabolism ; Sp1 Transcription Factor ... Individually or collectively, none of the three enhancer-binding proteins (LEF-1, Ets-1, and TFE-3) could activate ... en] Animals ; Base Sequence ; Binding Sites ; Cloning, Molecular ; DNA, Viral/metabolism ; DNA-Binding Proteins/metabolism ; ... protein that activates the T cell receptor alpha (TCR alpha) enhancer in a context-restricted manner in T cells. In this paper ...http://orbi.ulg.ac.be/handle/2268/135381
Mef2c is activated directly by Ets transcription factors through an evolutionarily conserved endothelial cell-specific enhancer...
Thus, these studies identify mef2c as a direct transcriptional target of Ets factors via an evolutionarily conserved ... This mef2c endothelial cell enhancer contains four perfect consensus Ets transcription factor binding sites that are ... efficiently bound by Ets-1 protein in vitro and are required for enhancer function in transgenic embryos. ... Proto-Oncogene Proteins, Proto-Oncogene Proteins c-ets, Sequence Alignment, Sequence Analysis, DNA, Transcription Factors, ...https://www.dpag.ox.ac.uk/publications/68224
Novel tempeh (fermented soyabean) isoflavones inhibit in vivo angiogenesis in the chicken chorioallantoic membrane assay. -...
The isoflavones also inhibited Ets 1 expression, providing some insight into the molecular mechanisms of their action. ... their capacity to inhibit vascular endothelial growth factor-induced endothelial cell proliferation and expression of the Ets 1 ... Proto-Oncogene Proteins c-ets, Proto-Oncogene Protein c-ets-1 ... New role for Wiskott-Aldrich Syndrome protein * NDORMS ... Proto-Oncogene Proteins, Transcription Factors, Cell Proliferation, Structure-Activity Relationship, Soy Foods, ...https://www.ndorms.ox.ac.uk/publications/271204
Efficacy of ETS-1 transcriptional silencing. Expression | Open-i
Expression level of ETS-1 in the Panc-1 cells was decreased after ETS-1 shRNA transfection. (A) Brightfield and flu ... Proto-Oncogene Protein c-ets-1/genetics*/metabolism. Minor. *Cadherins/genetics. *Cell Adhesion ... v-ets erythroblastosis virus E26 oncogene homolog 1 (ETS-1) plays crucial roles in a spectrum of malignancies. ETS-1 has gained ... v-ets erythroblastosis virus E26 oncogene homolog 1 (ETS-1) plays crucial roles in a spectrum of malignancies. ETS-1 has gained ...https://openi.nlm.nih.gov/detailedresult.php?img=PMC4306275_OR-33-02-0559-g01&req=4
Cumate Solution (1,000x in 95% Ethanol) | System Biosciences
2017) ETS Proto-oncogene 1 Transcriptionally Up-regulates the Cholangiocyte Senescence-associated Protein Cyclin-dependent ... Move your genome engineering projects forward with confidence with products for verifying Cas9 mRNA and protein expression. ... 2017) The Highly Dynamic Nature of ERdj5 Is Key to Efficient Elimination of Aberrant Protein Oligomers through ER-Associated ... Whether you're interested in characterizing exosomal RNA or proteins for biomarker profiling, SBI offers a range of intuitive, ...https://www.systembio.com/products/gene-expression-systems/cumate-inducible-systems/cumate-solution/
Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence. - The Christie Research Publications...
Proto-Oncogene Proteins. -. dc.subject.mesh. Proto-Oncogene Proteins c-ets. -. dc.subject.mesh. Proto-Oncogene Proteins c-raf. ... Proto-Oncogene Protein c-ets-2. -. dc.subject.mesh. ... Proto-Oncogene Protein c-ets-1. -. dc.subject.mesh. ... Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence.. Authors:. Ohtani, Naoko; Zebedee, ... Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence. 2001, 409 (6823):1067-70 Nature. en ...http://christie.openrepository.com/christie/handle/10541/85725
evolution - U.S. Transhumanist Party / Transhuman Party - Official Website
ETS1 - Chromosome 11 - (ETS Proto-Oncogene 1, Transcription Factor) is a Protein Coding gene. Among its related pathways are ... OXT - Chromosome 20 - (Oxytocin/Neurophysin I Prepropeptide) is a Protein Coding gene. This gene encodes a precursor protein ... DRD5 - Chromosome 4 - (Dopamine Receptor D5) is a Protein Coding gene. This receptor is expressed in neurons in the limbic ... GO annotations related to this gene include protein kinase activity and signal transducer activity. An important paralog of ...http://transhumanist-party.org/tag/evolution/
Genetic variability and functional implication of the long control region in HPV-16 variants in Southwest China
ETS proto-oncogene 1 (ETS1) and signal transducer and activator of transcription 3 (STAT3), respectively. While, the mutations ... For example, the E2 protein has been shown to be primarily a transcriptional repressor, and mutations of the E2 binding sites ... ETS transcription factors and their emerging roles in human cancer. Eur J Cancer. 2005; 41: 2462-2478. pmid:16213704 * View ... implied that deletions or mutations of YY1-binding sites played a significant role in the over-expression of viral oncogenes ...http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0182388
ELK1 Gene - GeneCards | ELK1 Protein | ELK1 Antibody
Protein Coding), ELK1, ETS Transcription Factor, including: function, proteins, disorders, pathways, orthologs, and expression ... complex by binding to the the serum response factor and the serum response element in the promoter of the c-fos proto-oncogene ... Protein Symbol:. P19419-ELK1_HUMAN. Recommended name:. ETS domain-containing protein Elk-1 Protein Accession:. P19419. ... ELK1 (ELK1, ETS Transcription Factor) is a Protein Coding gene. Diseases associated with ELK1 include Hypervitaminosis A. Among ...http://www.genecards.org/cgi-bin/carddisp.pl?gene=ELK1
FLI1 - Wikipedia
... is a protein that in humans is encoded by the FLI1 gene, which is a proto-oncogene. Fli-1 is a member of the ETS transcription ... 1998). "Erg proteins, transcription factors of the Ets family, form homo, heterodimers and ternary complexes via two distinct ... 1998). "The ets family member Tel binds to the Fli-1 oncoprotein and inhibits its transcriptional activity". J. Biol. Chem. 273 ... FLI1 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH) This article incorporates text from ...https://en.wikipedia.org/wiki/FLI1
Proto-oncogene 232 UniProt Keyword (15) Complete proteome 20,231 DNA-binding 2,008 ... This gene encodes a member of the ETS family of transcription factors, which are defined by the presence of a conserved ETS DNA ... These proteins function either as transcriptional activators or repressors of numerous genes, and are involved in stem cell ...https://pharos.nih.gov/idg/targets/P14921