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*  DNA and factor VII-activating protease protect against the cytotoxicity of histones | Blood Advances
... histone proteolysis by FSAP was more efficient than APC-mediated proteolysis (Figure 1B). ... Nevertheless, proteolysis of histones by FSAP seems efficient. FSAP binds to histones with high affinity (apparent Kd, 42 nM), ... F) Histone proteolysis after incubation in the presence of 1.3%, 2.5%, and 5% serum was determined in the samples from panel E ... The proteolysis of free histones may serve as a mechanism to protect against the harmful effects of free histones. Future ...
http://www.bloodadvances.org/content/1/26/2491?sso-checked=true
*  E. coli proteolysis
... Rob mbzrl at mbn1.biochem.nottingham.ac.uk Thu May 15 09:50:07 EST 1997 *Previous message: Green ... but seem to be having problems with proteolysis - we think this may be occuring at double basic sites but are not completely ...
http://www.bio.net/bionet/mm/proteins/1997-May/005555.html
*  Chemistry of proteolysis - Vladimir K. Antonov - Google Books
Proteolysis is the enzymatic hydrolysis of the amide bond in peptides and proteins. This book describes the chemical process ... books.google.com - Proteolysis is the enzymatic hydrolysis of the amide bond in peptides and proteins. This book describes the ... Proteolysis is the enzymatic hydrolysis of the amide bond in peptides and proteins. This book describes the chemical process ... It offers data on the regularities of the homogeneous...https://books.google.com/books/about/Chemistry_of_proteolysis.html?id= ...
https://books.google.com/books?id=OpYvAQAAIAAJ&dq=related:LCCN83178010&lr=&source=gbs_similarbooks_r&hl=en
*  Target-directed proteolysis at the ribosome | PNAS
Target-directed proteolysis at the ribosome. Tanja Henrichs, Natasha Mikhaleva, Charlotte Conz, Elke Deuerling, Dana Boyd, ... Target-directed proteolysis at the ribosome. Tanja Henrichs, Natasha Mikhaleva, Charlotte Conz, Elke Deuerling, Dana Boyd, ... Target-directed proteolysis at the ribosome. Tanja Henrichs, Natasha Mikhaleva, Charlotte Conz, Elke Deuerling, Dana Boyd, ... B) Proteolysis of SecA195 by cytoplasmic and ribosomal TEV protease. Western blot analysis was performed with anti-TEV antibody ...
https://www.pnas.org/content/102/12/4246/tab-figures-data
*  Limited Proteolysis | Thermo Fisher Scientific - AU
High resolution accurate mass MScombined with limited proteolysis aids in studying the quaternary structure of protein ... Sequencing can also be performed using limiting proteolysis. In this approach, enzymes are introduced in a limited amount with ...
https://www.thermofisher.com/au/en/home/industrial/mass-spectrometry/proteomics-protein-mass-spectrometry/proteomics-protein-mass-spectrometry-workflows/protein-structure-analysis-mass-spectrometry/limited-proteolysis.html
*  KEGG PATHWAY: Ubiquitin mediated proteolysis + T30050
Ubiquitin mediated proteolysis + T30050 [ Pathway menu , Organism menu , Pathway entry , Download KGML , Show description , ...
http://www.genome.jp/kegg-bin/show_pathway?T30050_04120+M00389
*  KEGG PATHWAY: Ubiquitin mediated proteolysis + T30020
Ubiquitin mediated proteolysis + T30020 [ Pathway menu , Organism menu , Pathway entry , Download KGML , Show description , ...
http://www.genome.jp/kegg-bin/show_pathway?T30020_04120+M00382
*  Calpain-mediated proteolysis of talin regulates adhesion dynamics. - PubMed - NCBI
Calpain-mediated proteolysis of talin regulates adhesion dynamics.. Franco SJ1, Rodgers MA, Perrin BJ, Han J, Bennin DA, ... Here, we show that proteolysis of talin by the intracellular calcium-dependent protease calpain is critical for focal adhesion ... We have generated a single point mutation in talin that renders it resistant to proteolysis by calpain. Quantification of ... Together, these findings identify calpain-mediated proteolysis of talin as a mechanism by which adhesion dynamics are regulated ...
https://www.ncbi.nlm.nih.gov/pubmed/15448700?dopt=Abstract
*  Structural basis for intramembrane proteolysis by rhomboid serine proteases | PNAS
Structural basis for intramembrane proteolysis by rhomboid serine proteases Message Subject (Your Name) has sent you a message ... Structural basis for intramembrane proteolysis by rhomboid serine proteases. Adam Ben-Shem, Deborah Fass, and Eitan Bibi ... Intramembrane proteolysis is catalyzed by polytopic integral membrane enzymes (1). Through the controlled release of membrane- ... 1 A). The architectural principles that allow water-mediated proteolysis within the lipid bilayer interior may apply to other ...
https://www.pnas.org/content/104/2/462?ijkey=eb716a5eb42d25b42fc87861aad0c5c0fd89b836&keytype2=tf_ipsecsha
*  Proteolysis | definition of proteolysis by Medical dictionary
... proteolysis explanation free. What is proteolysis? Meaning of proteolysis medical term. What does proteolysis mean? ... Looking for online definition of proteolysis in the Medical Dictionary? ... proteolysis. Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia. proteolysis. [pro″te-ol´ĭ-sis] the splitting of ... proteolysis. the splitting of protein molecules by the HYDROLYSIS of their PEPTIDE BONDS.. proteolysis. the splitting of ...
https://medical-dictionary.thefreedictionary.com/proteolysis
*  Angiogenesis in Vitro: Cytokine Interactions and Balanced Extracellular Proteolysis | SpringerLink
Cytokine Interactions and Balanced Extracellular Proteolysis. In: Maragoudakis M.E., Gullino P.M., Lelkes P.I. (eds) ... interactions between angiogenesis-modulating cytokines and the role of balanced extracellular proteolysis. M.D. thesis, Faculty ...
https://link.springer.com/chapter/10.1007/978-1-4757-9188-4_19
*  Platelet Receptor Proteolysis | Arteriosclerosis, Thrombosis, and Vascular Biology
Proteolysis of the cytoplasmic tail of β3 by calpain abolishes αIIbβ3-dependent clot contraction. Both calmodulin and calpain ... Platelet Receptor Proteolysis. A Mechanism for Downregulating Platelet Reactivity. Robert K. Andrews, Denuja Karunakaran, ... Extracellular proteolysis of receptors irreversibly inactivates receptor-mediated adhesion and signaling, as well as releasing ... Clinical Implications of Platelet Proteolysis. The pathology of thrombus formation in thrombotic disease can be described as a ...
http://atvb.ahajournals.org/content/27/7/1511.full
*  Intraluminal thrombus enhances proteolysis in abdominal aortic aneurysms.
... is a source of fibrinolytic activity and proteolysis that could weaken the aneurysm wall. Plasmin, tissue plasminogen activator ... Plasmin activation of MMPs at the interface between intraluminal thrombus and the aneurysm wall may enhance proteolysis and ... is a source of fibrinolytic activity and proteolysis that could weaken the aneurysm wall. Plasmin, tissue plasminogen activator ...
http://www.biomedsearch.com/nih/Intraluminal-thrombus-enhances-proteolysis-in/16849017.html
*  Cut2 proteolysis required for sister-chromatid seperation in fission yeast. - PubMed - NCBI
Cut2 proteolysis required for sister-chromatid seperation in fission yeast.. Funabiki H1, Yamano H, Kumada K, Nagao K, Hunt T, ... Here we report the anaphase-specific proteolysis of the Schizosaccharomyces pombe Cut2 protein, which is essential for sister- ... Although mitotic cyclins are well-known substrates for ubiquitin-mediated proteolysis at the metaphase-anaphase transition, ... their degradation is not essential for separation of sister chromatids; several lines of evidence suggest that proteolysis of ...
https://www.ncbi.nlm.nih.gov/pubmed/8632802?dopt=Abstract
*  2018 Plasminogen Activation and Extracellular Proteolysis (GRS) Seminar GRC
The 2018 Gordon Research Seminar on Plasminogen Activation and Extracellular Proteolysis (GRS) will be held in Ventura, CA. ... Extracellular Proteolysis in Tissue Development, Homeostasis, and Repair Discussion Leaders: Brittany Aicher (University of ... Extracellular Proteolysis in Regulation of Innate Immune Responses, Inflammation and Cancer / Keynote Session: Biophysical ... The Gordon Research Seminar on Plasminogen Activation and Extracellular Proteolysis is a unique forum for graduate students, ...
https://www.grc.org/plasminogen-activation-and-extracellular-proteolysis-grs-conference/2018/
*  Protease that decomposes proteins recalcitrant to proteolysis - Microbial Chemistry Research Foundation
... pure cultures of microorganisms high in protease activity and capable of decomposing proteins recalcitrant to proteolysis as ... 99-GP-2-D-5 (FERM P-19336) capable of producing a protease decomposing protein recalcitrant to proteolysis and microbial ... The protease capable of decomposing proteins recalcitrant to proteolysis of the present invention preferably has a N terminus ... The present invention also provides a protease capable of decomposing proteins recalcitrant to proteolysis which is obtained by ...
http://www.freepatentsonline.com/8765441.html
*  Enhancing immunogenicity by limiting susceptibility to lysosomal proteolysis | JEM
Limited lysosomal proteolysis of HRP results in enhanced immunogenicity. (A) HRP (H) and apo-HRP (a) give rise only to complete ... Enhancing immunogenicity by limiting susceptibility to lysosomal proteolysis. Lélia Delamarre, Rachael Couture, Ira Mellman, E ... Differential susceptibility of RNase-A and RNase-S to lysosomal proteolysis. (A) RNase-A, RNase-S, and their FITC derivatives ... Proteolysis in MHC class II antigen presentation: who's in charge? Immunity. 12:233-239. ...
http://jem.rupress.org/content/203/9/2049
*  Apolipoprotein A-I proteolysis in aortic valve stenosis: role of cathepsin S | SpringerLink
ApoA-I proteolysis is increased in AVS. Targeting circulating cathepsin S may lead to new therapies for human aortic valve ... Mendez AJ, Oram JF (1997) Limited proteolysis of high density lipoprotein abolishes its interaction with cell-surface binding ... Apolipoprotein A-I proteolysis in aortic valve stenosis: role of cathepsin S. ...
https://link.springer.com/article/10.1007%2Fs00395-018-0689-7
*  Proteolysis - PrimePCR | Life Science | Bio-Rad
View our wet-lab validated real-time PCR primer assays for your cell signaling pathway of interest. Use our predesigned PCR plates or customize your own.
http://www.bio-rad.com/en-us/prime-pcr-assays/pathway/proteolysis
*  JCI - CHK1 targets spleen tyrosine kinase (L) for proteolysis in hepatocellular carcinoma
CHK1 targets spleen tyrosine kinase (L) for proteolysis in hepatocellular carcinoma. Jian Hong,1,2 Kaishun Hu,1,3 Yunfei Yuan,1 ... GSK-3 beta targets Cdc25A for ubiquitin-mediated proteolysis, and GSK-3 beta inactivation correlates with Cdc25A overproduction ...
https://www.jci.org/articles/view/61380
*  Proteolysis - Wikipedia
Consequently, dis-regulation of proteolysis can cause disease and is used by some venoms. Proteolysis is important as an ... Low pH or high temperatures can also cause proteolysis non-enzymatically. Proteolysis in organisms serves many purposes; for ... The rate of proteolysis may also depend on the physiological state of the organism, such as its hormonal state as well as ... The rate of proteolysis however can be significantly increased by extremes of pH and heat. Strong mineral acids can readily ...
https://en.wikipedia.org/wiki/Proteolysis
*  Extracellular Proteolysis of Apolipoprotein E (apoE) by Secreted Serine Neuronal Protease
Proteolysis of apoE4 generated higher levels of low molecular weight fragments compared to apoE3. Primary glial cultures ... Here we identified a novel way by which apoE undergoes proteolysis in the extracellular space via a secreted neuronal protease ...
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0093120
*  Post-translational Modifications, Proteolysis & Proteomics | Molecular Systems Biology
SWATH‐MS combines deep proteome coverage with quantitative consistency and accuracy and is often the method of choice for personalized medicine, drug screens or systems biology. This tutorial provides guidelines on how to set up SWATH‐MS experiments, perform the mass spectrometric measurements and analyse the data. ...
http://msb.embopress.org/collection/post-translational-modifications-proteolysis-proteomics
*  Post-translational Modifications, Proteolysis & Proteomics | EMBO Molecular Medicine
Mendelian hypertension is rare; however, Mendelian syndromes have taught us an amazing amount about mechanisms of distal sodium and chloride reabsorption, as well as how systemic hypertension might come about. In this issue of EMBO Molecular Medicine, Schumacher et al (2015) present a mouse model of the Cullin‐3 (CUL3Δ403-459) mutation, which causes a form of pseudohypoaldosteronism type‐2 (PHA‐2). CUL3 is involved in ubiquitination. Surprising is the severity of the hypertension, which may be explained in part on the basis of CUL3 actions in vascular cells. The findings underscore the role of "cleanup" in the maintenance of normal physiology.. See also: F‐R Schumacher et al (October 2015) ...
http://embomolmed.embopress.org/collection/post-translational-modifications-proteolysis-proteomics