Protein phosphorylation - Wikipedia
Protein phosphorylation is a reversible post-translational modification of proteins. In eukaryotes, protein phosphorylation ... Compared to the protein phosphorylation of prokaryotes, studies of protein phosphorylation in eukaryotes from yeast to human ... its interactions with other proteins may be regulated by phosphorylation of these interacting proteins. Phosphorylation ... Phosphorylation of the enzyme GSK-3 by AKT (Protein kinase B) as part of the insulin signaling pathway. Phosphorylation of Src ...
Systematic phosphorylation analysis of human mitotic protein complexes
Most, if not all, of the mitotic processes are regulated by a set of mitotic protein kinases that control protein act … ... Progression through mitosis depends on a large number of protein complexes that regulate the major structural and physiological ... of the mitotic processes are regulated by a set of mitotic protein kinases that control protein activity by phosphorylation. ... Systematic phosphorylation analysis of human mitotic protein complexes Sci Signal. 2011 Nov 8;4(198):rs12. doi: 10.1126/ ...
Protein-analysis] 2010 Symposium on Plant Protein Phosphorylation
... Kroll, Melody M. via proteins%40net.bio.net (by krollmm from ... The Symposium on Plant Protein Phosphorylation provides an interdisciplinary research venue for scholars studying protein ... ANNOUNCEMENT * 2010 SYMPOSIUM ON PLANT PROTEIN PHOSPHORYLATION BOND LIFE SCIENCES CENTER COLUMBIA, MISSOURI, USA MAY 26-28, ... is part of an ongoing series of international meetings on protein phosphorylation in plants. This years Symposium will include ...
Protein Phosphorylation | Lund University Publications
RegPhos 2.0: an updated resource to explore protein kinase-substrate phosphorylation networks in mammals
Owing to an increasing number of in vivo phosphorylation sites that have been identified by mass spectrometry (MS)-based ... Protein phosphorylation catalyzed by kinases plays crucial roles in regulating a variety of intracellular processes. ... RegPhos 2.0: an updated resource to explore protein kinase-substrate phosphorylation networks in mammals Database (Oxford). ... Protein phosphorylation catalyzed by kinases plays crucial roles in regulating a variety of intracellular processes. Owing to ...
inhibitory G-protein coupled receptor phosphorylation Antibodies | Invitrogen ...
PRIME PubMed | FK506-binding protein 52 phosphorylation: a potential mechanism for regulating steroid hormone receptor activity
FK506-binding protein 52 phosphorylation: a potential mechanism for regulating steroid hormone receptor activity. Download ... FK506-binding protein 52 phosphorylation: a potential mechanism for regulating steroid hormone receptor activity.. Mol ... "FK506-binding Protein 52 Phosphorylation: a Potential Mechanism for Regulating Steroid Hormone Receptor Activity." Molecular ... FK506-binding protein 52 phosphorylation: a potential mechanism for regulating steroid hormone receptor activity. Mol ...
Molecular Vision: Inhibition of p38 mitogen-activated protein kinase phosphorylation decrease tert-butyl hydroperoxide...
Protein concentration was determined using Bio-Rad Protein Assay Kit II (Bio-Rad Lab). The proteins were separated by 10% ... Inhibition of p38 mitogen-activated protein kinase phosphorylation decrease tert-butyl hydroperoxide-induced apoptosis in human ... Mitogen-activated protein kinases (MAPKs) comprise a large family of proteins activated by a wide range of proinflammatory ... implied that the proteins downstream to phospho-p38MAPK could not be activated after blockage of the p38MAPK phosphorylation by ...
Cyclic GMP-dependent protein kinase stimulates the plasmalemmal Ca2+ pump of smooth muscle via phosphorylation of...
The effect of phosphorylation by cyclic GMP-dependent protein kinase (G-kinase) on the activity of the plasmalemmal Ca2+- ... Cyclic GMP-dependent protein kinase stimulates the plasmalemmal Ca2+ pump of smooth muscle via phosphorylation of ... Evidence is presented showing that the apparent phosphorylation occurs in a contaminant protein, possibly myosin light-chain ... Cyclic GMP-dependent protein kinase stimulates the plasmalemmal Ca2+ pump of smooth muscle via phosphorylation of ...
Evidence for Biphasic Effects of Protein Kinase C on Serotonin Transporter Function, Endocytosis, and Phosphorylation |...
Protein kinase C (PKC)-mediated phosphorylation of SERT occurs on the plasma membrane during the initial phase of rapid ... Evidence for Biphasic Effects of Protein Kinase C on Serotonin Transporter Function, Endocytosis, and Phosphorylation. ... Evidence for Biphasic Effects of Protein Kinase C on Serotonin Transporter Function, Endocytosis, and Phosphorylation. ... Evidence for Biphasic Effects of Protein Kinase C on Serotonin Transporter Function, Endocytosis, and Phosphorylation. ...
Proteomic analysis of ERK1/2-mediated human sickle red blood cell membrane protein phosphorylation.
Proteomic analysis of ERK1/2-mediated human sickle red blood cell membrane protein phosphorylation. ... RESULTS: To further characterize global ERK1/2-induced changes in membrane protein phosphorylation within human RBCs, a label- ... Proteomic analysis of ERK1/2-mediated human sickle red blood cell membrane protein phosphorylation. Clin Proteomics, 10(1). pp ... of misfolded proteins and receptor ubiquitination. Glycophorin A was the most affected protein in sickle RBCs by this ERK1/2 ...
Shade-induced nuclear localization of PIF7 is regulated by phosphorylation and 14-3-3 proteins in Arabidopsis | eLife
A phosphorylation dependent translocation of PIF7 and involvement of 14-3-3 proteins reveal novel regulation mechanisms in ... phosphorylation of PIF7 results in the cytoplasmic location of this protein and enables its binding to 14-3-3 proteins. When ... Phosphorylation sites of PIF7 mediate its binding to 14-3-3 proteins. There are two types of specific 14-3-3 binding motifs in ... Phosphorylation sites of PIF7 are important for the localization and function of this protein.. (a) Subcellular localization of ...
"Increased Insulin-like Growth Factor Binding Protein-1 Phosphorylation" by Sahil S Singal, Karen Nygard et al.
To test the hypothesis that human IUGR is associated with increased decidual IGFBP-1 phosphorylation at discrete sites, we used ... Together, our data links for the first time, increased decidual IGFBP-1 phosphorylation at discrete sites with human IUGR. ... we found that IGFBP-1 phosphorylation (pSer101; +40%, p=0.0677/pSer119; +60%, p=0.0064/pSer169; +100%, p=0.0021) was markedly ... reported that hypoxia and/or leucine deprivation triggered hyperphosphorylation of insulin-like growth factor binding protein-1 ...
Angiotensin AT1 Receptor Phosphorylation and Desensitization in a Hepatic Cell Line. Roles of Protein Kinase C and...
Angiotensin AT1 Receptor Phosphorylation and Desensitization in a Hepatic Cell Line. Roles of Protein Kinase C and ... Angiotensin AT1 Receptor Phosphorylation and Desensitization in a Hepatic Cell Line. Roles of Protein Kinase C and ... Angiotensin AT1 Receptor Phosphorylation and Desensitization in a Hepatic Cell Line. Roles of Protein Kinase C and ... Angiotensin AT1 Receptor Phosphorylation and Desensitization in a Hepatic Cell Line. Roles of Protein Kinase C and ...
1244-P: The Protein Phosphatase PPm1k Regulates Ribosomal Protein S6 Phosphorylation in Beta Cells | Diabetes | American...
Phosphorylation of ribosomal protein S6 (RPS6) on ser235/236 and ser240/244 in the pancreatic beta cell increases cell size and ... 1244-P: The Protein Phosphatase PPm1k Regulates Ribosomal Protein S6 Phosphorylation in Beta Cells YANN DELEYE; YANN DELEYE ... The Protein Phosphatase PPm1k Regulates Ribosomal Protein S6 Phosphorylation in Beta Cells. Diabetes 1 June 2021; 70 ( ... Phosphorylation of ribosomal protein S6 (RPS6) on ser235/236 and ser240/244 in the pancreatic beta cell increases cell size and ...
Phosphorylation of multiple proteins involved in ciliogenesis by Tau Tubulin Kinase 2 | Faculty of Medicine Masaryk University ...
Phosphorylation of multiple proteins involved in ciliogenesis by Tau Tubulin Kinase 2. ... Phosphorylation of multiple proteins involved in ciliogenesis by Tau Tubulin Kinase 2 ... Finally, we show that TTBK2 is also required for efficient phosphorylation of many S/T sites in CEP164 and provide evidence ... To initiate their assembly, coordinated actions of multiple proteins are needed. Tau tubulin kinase 2 (TTBK2) is a key player ...
Predikin and PredikinDB: a computational framework for the prediction of protein kinase peptide specificity and an associated...
Predikin now consists of two components: (i) PredikinDB, a database of phosphorylation sites that links substrates to kinase ... The new features significantly enhance the ability of Predikin to analyse protein kinases and their substrates. Predikin is ... contact the substrate in the region of the phosphorylation site and so determine the sequence surrounding the phosphorylation ... generate scoring matrices and score putative phosphorylation sites in query sequences. The performance of Predikin as measured ...
G-protein-dependent and -independent pathways regulate proteinase-activated receptor-2 mediated p65 nf kappa b serine 536...
... predominantly G-protein-independent pathway involved in PAR-2 regulation of NFκB phosphorylation in keratinocytes. ... Goh, F.G. and Sloss, C.M. and Cunningham, M.R. and Nilsson, M. and Cadalbert, Laurence and Plevin, R.J. (2008) G-protein- ... also did not effect NFκB phosphorylation. Taken together these data indicate dependency for Gq/11 in early phosphorylation of ... G-protein-dependent and -independent pathways regulate proteinase-activated receptor-2 mediated p65 nf kappa b serine 536 ...
Biochemical studies of the excitable membrane of Paramecium tetraurelia VI. Endogenous protein substrates for in vitro and in...
The endogenous protein kinases of isolated Paramecium tetraurelia cilia phosphorylated approximately 30 ciliary polypeptides in ... Endogenous protein substrates for in vitro and in vivo phosphorylation in cilia and ciliary membranes. R M Lewis, R M Lewis ... Endogenous protein substrates for in vitro and in vivo phosphorylation in cilia and ciliary membranes.. J Cell Biol 1 October ... showed normal patterns of ciliary protein phosphorylation in vitro, with and without added cyclic nucleotides, at both pH 6.0 ...
Protein Phosphorylation | LUDC
Protein phosphorylation is a biological process that regulates most aspects of cellular life, and the enzymes that catalyze ... An overall aim of our research is to study the regulation and function of protein phosphorylation cascades that are important ... We are currently investigating two protein kinases, namely AMP-activated protein kinase (AMPK) and Salt-inducible kinase 2 ( ... Our work on SIK2 will address if downregulation of this protein is a causative factor in development of obesity and insulin ...
Protein phosphorylation-dependent regulation of circadian timekeeping<...
Protein phosphorylation-dependent regulation of circadian timekeeping. Masao Doi*, Toshiyuki Okano. *Corresponding author for ... Protein phosphorylation-dependent regulation of circadian timekeeping. / Doi, Masao; Okano, Toshiyuki. In: Seikagaku. The ... Protein phosphorylation-dependent regulation of circadian timekeeping. Seikagaku. The Journal of Japanese Biochemical Society. ... Doi, M., & Okano, T. (2005). Protein phosphorylation-dependent regulation of circadian timekeeping. Seikagaku. The Journal of ...
Trifluoperazine inhibits hippocampal long-term potentiation and the phosphorylation of a 40,000 dalton protein. - Department of...
In addition, calmodulin stimulates and TFP inhibits the phosphorylation of the 40,000 dalton protein (as well as that of ... several other proteins) in a dose-dependent fashion. ... and changes in the endogenous phosphorylation of a 40,000 ... dalton protein in the hippocampus in a calcium-dependent manner. In the present paper we report that 40 microM trifluoperazine ... Trifluoperazine inhibits hippocampal long-term potentiation and the phosphorylation of a 40,000 dalton protein. ...
Protein Phosphorylation - Profiles - Lund University
Protein Phosphorylation - Principal investigator, Research team manager, Professor. *Department of Experimental Medical Science ... Glucose Transport and Protein Trafficking - Research engineer. *EXODIAB: Excellence of Diabetes Research in Sweden - Research ...
Plasmodium vivax inhibits erythroid cell growth through altered phosphorylation of the cytoskeletal protein ezrin | Malaria...
These proteins display interactions and are involved in the regulation of the cellular cytoskeleton. Particularly affected was ... findings suggest that parasite proteins are able to inhibit erythroid cell growth by down-regulation of ezrin phosphorylation, ... Inhibitory effect on erythroid cell growth by P. vivax is regulated by ezrin phosphorylation. Protein phosphorylation is ... The protein-protein interaction networks determined using the KEGG human protein database revealed that ezrin functions in ...
Argonaute Utilization for miRNA Silencing Is Determined by Phosphorylation-Dependent Recruitment of LIM-Domain-Containing...
As core components of the microRNA-induced silencing complex (miRISC), Argonaute (AGO) proteins interact with TNRC6 proteins, ... Evaluating how phosphorylation alters the structure/function relationship of the microRNA biogenesis protein TRBP. Plevin, M. J ... proteins interact with TNRC6 proteins, recruiting other effectors of translational repression/mRNA destabilization. Here, we ... proteins interact with TNRC6 proteins, recruiting other effectors of translational repression/mRNA destabilization. Here, we ...
Phosphorylation of two cytosolic proteins. An early event of T-cell activation - Wikidata
Phosphorylation of two cytosolic proteins. An early event of T-cell activation (English) ... Phosphorylation of two cytosolic proteins. An early event of T-cell activation. scientific article ... Changes in Protein Phosphorylation in Rous Sarcoma Virus-Transformed Chicken Embryo Cells ... Further evidence for a phospholipase C-coupled G protein in hamster fibroblasts. Induction of inositol phosphate formation by ...
Scholarly Article or Book Chapter | G-Protein Phosphorylation: Aspects of Binding Specificity and Function in the Plant Kingdom...
G-Protein Phosphorylation: Aspects of Binding Specificity and Function in the Plant Kingdom ... protein. With a small repertoire of G proteins in plants, phosphorylation by receptor kinases is critical in regulating the ... Oliveira, C., Jones, A., Pacheco Batista Fontes, E., & Braga Dos Reis, P. (2022). G-Protein Phosphorylation: Aspects of Binding ... G-Protein Phosphorylation: Aspects of Binding Specificity and Function in the Plant Kingdom. Public Deposited ...
Protein and phosphorylation profiling | scioPhospho
Highly parallel protein expression and phosphorylation status analysis with antibody microarrays ... 1,300 highly relevant proteins are profiled in a single assay. *Phosphorylation status combined with protein expression levels ... Features 1,300 highly relevant proteins are profiled in a single assay Phosphorylation status combined with protein expression ... protein profiling and phosphorylation status scioPhospho combines the advantages of a robust and cost-efficient protein ...
scioPhospho: protein profiling and phosphorylation status
... highly parallel protein analyses with antibody microarrays for pathway profiling, biomarker discovery and verification. ... 1,300 highly relevant proteins are profiled in a single assay. *Phosphorylation status combined with protein expression levels ... Features 1,300 highly relevant proteins are profiled in a single assay Phosphorylation status combined with protein expression ... protein profiling and phosphorylation status. scioPhospho combines the advantages of a robust and cost-efficient protein ...