ATP binding to the sigma 54-dependent activator XylR triggers a protein multimerization cycle catalyzed by UAS DNA.  - PubMed -...ATP binding to the sigma 54-dependent activator XylR triggers a protein multimerization cycle catalyzed by UAS DNA. - PubMed -...

ATP binding to the sigma 54-dependent activator XylR triggers a protein multimerization cycle catalyzed by UAS DNA.. Pérez- ... ATP hydrolysis by XylR, the cognate regulator of the system, is preceded by the multimerization of XylR at the enhancer, which ... is itself triggered by the sole allosteric effect of ATP binding to the protein. Since ADP is unable to support multimerization ... This notion is supported further by the properties of mutant proteins that seem to be frozen, in either the nonmultimerized or ...
more infohttps://www.ncbi.nlm.nih.gov/pubmed/8706137?dopt=Abstract

Adipocyte Spliced Form of X-Box-Binding Protein 1 Promotes Adiponectin Multimerization and Systemic Glucose Homeostasis |...Adipocyte Spliced Form of X-Box-Binding Protein 1 Promotes Adiponectin Multimerization and Systemic Glucose Homeostasis |...

Protein Lysates, Immunoprecipitation, and Western Blot. Protein lysate, cytosol and nuclear protein extraction, ... protein disulfide isomerase family A, member 6, ER protein 44, and disulfide bond oxidoreductase A-like protein. Thus, we ... A disulfide-bond A oxidoreductase-like protein (DsbA-L) regulates adiponectin multimerization. Proc Natl Acad Sci USA 2008;105: ... Adipocyte Spliced Form of X-Box-Binding Protein 1 Promotes Adiponectin Multimerization and Systemic Glucose Homeostasis. ...
more infohttp://diabetes.diabetesjournals.org/content/63/3/867.full

Adipocyte Spliced Form of X-Box-Binding Protein 1 Promotes Adiponectin Multimerization and Systemic Glucose Homeostasis |...Adipocyte Spliced Form of X-Box-Binding Protein 1 Promotes Adiponectin Multimerization and Systemic Glucose Homeostasis |...

Protein Lysates, Immunoprecipitation, and Western Blot. Protein lysate, cytosol and nuclear protein extraction, ... protein disulfide isomerase family A, member 6, ER protein 44, and disulfide bond oxidoreductase A-like protein. Thus, we ... A disulfide-bond A oxidoreductase-like protein (DsbA-L) regulates adiponectin multimerization. Proc Natl Acad Sci USA 2008;105: ... Adipocyte Spliced Form of X-Box-Binding Protein 1 Promotes Adiponectin Multimerization and Systemic Glucose Homeostasis. ...
more infohttp://diabetes.diabetesjournals.org/content/63/3/867?ijkey=a7d6b270b8169df2a874893c14e3a247c03faeae&keytype2=tf_ipsecsha

Biochemical properties of bacterial reverse transcriptase-related (rvt) gene products: multimerization, protein priming, and...Biochemical properties of bacterial reverse transcriptase-related (rvt) gene products: multimerization, protein priming, and...

Biochemical properties of bacterial reverse transcriptase-related (rvt) gene products: multimerization, protein priming, and ... The C-terminal domain may be capable of protein priming, which is abolished by site-directed mutagenesis of the catalytic ... Furthermore, we investigated the highly conserved N- and C-terminal domains, which distinguish RVT proteins from other RTs. We ... To investigate biochemical properties of bacterial RVTs, we conducted in vitro studies of recombinant HaRVT protein from the ...
more infohttp://vivo.mblwhoilibrary.org/display/publication232766

Biochemical properties of bacterial reverse transcriptase-related (rvt) gene products : multimerization, protein priming, and...Biochemical properties of bacterial reverse transcriptase-related (rvt) gene products : multimerization, protein priming, and...

Biochemical properties of bacterial reverse transcriptase-related (rvt) gene products : multimerization, protein priming, and ... Oligomer; Reverse transcription; RNA-dependent DNA polymerase; Coiled-coil; Multimerization Abstract. Cellular reverse ... The C-terminal domain may be capable of protein priming, which is abolished by site-directed mutagenesis of the catalytic ... Further, we investigated the highly conserved N- and C-terminal domains, which distinguish RVT proteins from other RTs. We show ...
more infohttps://darchive.mblwhoilibrary.org/handle/1912/10375

A scissor blade-like closing mechanism implicated in transmembrane signaling in a Bacteroides hybrid two-component system.A scissor blade-like closing mechanism implicated in transmembrane signaling in a Bacteroides hybrid two-component system.

Protein Binding. Protein Kinases / chemistry, genetics, metabolism. Protein Multimerization. Protein Structure, Tertiary. ... 0/Bacterial Proteins; 9005-49-6/Heparin; 9050-30-0/Heparitin Sulfate; EC 2.7.-/Protein Kinases ... Bacterial Proteins / chemistry, genetics, metabolism*. Bacteroides / genetics, metabolism*. Binding Sites / genetics. Cell ... 22539977 - Role of dlg5/lp-dlg, a membrane-associated guanylate kinase family protein, in epitheli.... 22387217 - Indirubin ...
more infohttp://www.biomedsearch.com/nih/scissor-blade-like-closing-mechanism/22532667.html

Insights into the regulation of the human COP9 signalosome catalytic subunit, CSN5/Jab1.Insights into the regulation of the human COP9 signalosome catalytic subunit, CSN5/Jab1.

Protein Multimerization. Protein Structure, Quaternary. Protein Structure, Tertiary. Protein Subunits. Recombinant Fusion ... 0/Intracellular Signaling Peptides and Proteins; 0/NEDD8 protein, human; 0/Protein Subunits; 0/Recombinant Fusion Proteins; 0/ ... Intracellular Signaling Peptides and Proteins / chemistry*, genetics, metabolism*. Models, Molecular. Molecular Dynamics ... Ubiquitins; 74-79-3/Arginine; 7440-66-6/Zinc; EC 3.4.-/Peptide Hydrolases; EC 3.4.-.-/COPS5 protein, human ...
more infohttp://www.biomedsearch.com/nih/Insights-into-regulation-human-COP9/23288897.html

Lynch M[au] - PubMed - NCBILynch M[au] - PubMed - NCBI

Stochastic protein multimerization, activity, and fitness.. Hagner K, Setayeshgar S, Lynch M. ... Evolution of protein interfaces in multimers and fibrils.. Zabel WJ, Hagner KP, Livesey BJ, Marsh JA, Setayeshgar S, Lynch M, ...
more infohttps://www.ncbi.nlm.nih.gov/pubmed?cmd=search&term=Lynch+M%5Bau%5D&dispmax=50

Constrained solution scattering modelling of human antibodies and complement proteins reveals novel biological insights |...Constrained solution scattering modelling of human antibodies and complement proteins reveals novel biological insights |...

Complications arise if protein multimerization occurs. The complement fragment C3d is a 35 kDa cleavage fragment of C3b that ... 7. Modelling of protein-protein complexes. The utility of constrained modelling is enhanced by its extension to protein-protein ... 2007 Small-angle X-ray scattering from RNA, proteins, and protein complexes. Annu. Rev. Biophys. Biomol. Struct. 36, 307-327. ( ... It is applicable to protein sizes above approximately 15 kDa. The first overall views of many protein structures have been ...
more infohttp://rsif.royalsocietypublishing.org/content/6/Suppl_5/S679

The Hp UreI urea channel hexamera, Ribbon diagram of he | Open-iThe Hp UreI urea channel hexamera, Ribbon diagram of he | Open-i

This central lipid plug is reminiscent of those reported for other membrane protein oligomers such as bacteriorhodopsin9. The ... This central lipid plug is reminiscent of those reported for other membrane protein oligomers such as bacteriorhodopsin9. The ...
more infohttps://openi.nlm.nih.gov/detailedresult.php?img=PMC3974264_nihms416126f1&req=4

Role of p40 is conserved for the murine IL-12p70 produc | Open-iRole of p40 is conserved for the murine IL-12p70 produc | Open-i

Protein Multimerization*. Minor. *Animals. *Humans. *Immunotherapy. *Macaca mulatta. *Melanoma/genetics/immunology/metabolism/ ...
more infohttps://openi.nlm.nih.gov/detailedresult.php?img=PMC3585113_zbc0131341010002&req=4

Pharmaceuticals | Free Full-Text | A Short Peptide Inhibitor as an Activity-Based Probe for Matriptase-2Pharmaceuticals | Free Full-Text | A Short Peptide Inhibitor as an Activity-Based Probe for Matriptase-2

Looking for Novel Capsid Protein Multimerization Inhibitors of Feline Immunodeficiency Virus. Previous Article in Journal. The ...
more infohttps://www.mdpi.com/1424-8247/11/2/49

Publications | Biodesign Institute | ASUPublications | Biodesign Institute | ASU

Stochastic protein multimerization, activity, and fitness. Phys. Rev. E 98: 062401.Warren, W. C., R. García-Pérez, S. Xu, K. P ... Simple evolutionary pathways to complex proteins. Protein Science 14: 2217-2225. PDF ... Evolution of protein interfaces in multimers and fibrils. J. Chem. Physics 150: 225102. ... Evolutionary diversification of the multimeric states of proteins. Proc. Natl. Acad. Sci. USA 110: E2821-E2828.PDF ...
more infohttps://biodesign.asu.edu/michael-lynch/publications

ZFIN Publication: Yu et al., 2015ZFIN Publication: Yu et al., 2015

Protein Multimerization. *Recombinant Fusion Proteins/chemistry. *Transfection. *Zebrafish. PubMed:. 26098020 Full text @ Nat. ... A naturally monomeric infrared fluorescent protein for protein labeling in vivo. Yu, D., Baird, M.A., Allen, J.R., Howe, E.S., ... Infrared fluorescent proteins (IFPs) provide an additional color to GFP and its homologs in protein labeling. Drawing on ... A naturally monomeric infrared fluorescent protein for protein labeling in vivo. Nature Methods. 12(8):763-5. ...
more infohttps://zfin.org/ZDB-PUB-150623-3

Subcompartments of the macrophage recycling endosome direct the differential secretion of IL-6 and TNFα | JCBSubcompartments of the macrophage recycling endosome direct the differential secretion of IL-6 and TNFα | JCB

Lumenal protein multimerization in the distal secretory pathway/secretory granules. Curr. Opin. Cell Biol. 14:448-453. ... The supernatant was assayed for protein content (Bio-Rad Laboratories protein assay), and 20-50 μg of total protein from each ... GAIP, a Galphai-3-binding protein, is associated with Golgi-derived vesicles and protein trafficking. Am. J. Physiol. 276:C497- ... utilizing specific soluble NSF attachment protein receptor (SNARE) proteins to fuse with the recycling endosome. Within ...
more infohttp://jcb.rupress.org/content/178/1/57.long

SMBE Satellite Meeting, Mechanisms of Protein Evolution IISMBE Satellite Meeting, "Mechanisms of Protein Evolution II"

Michael Lynch (Indiana) described a model for the evolution of protein multimerization state. Jeff Thorne (North Carolina State ... SMBE Satellite Meeting, Mechanisms of Protein Evolution II. Mechanisms of Protein Evolution II was held as an SMBE Satellite ... These proteins share the TSP C-terminal region domain architecture, as determined by domain composition and analysis of ... In the meeting, many themes touching on protein evolution were touched upon and several of the talks are mentioned below. Andy ...
more infohttps://www.smbe.org/smbe/MEETINGS/MeetingAnnouncements/TabId/337/ArtMID/1392/ArticleID/19/SMBE-Satellite-Meeting-Mechanisms-of-Protein-Evolution-II.aspx

Synthetic oligodeoxynucleotides containing suppressive TTAGGG motifs i by John J. Kaminski III, Stefan A. Schattgen et al."Synthetic oligodeoxynucleotides containing suppressive TTAGGG motifs i" by John J. Kaminski III, Stefan A. Schattgen et al.

Nuclear Proteins; *Nucleotide Motifs; Oligodeoxyribonucleotides; Protein Binding; Protein Multimerization; Signal Transduction ... Animals; Anti-Inflammatory Agents; Cell Line; Cluster Analysis; Cytoskeletal Proteins; Cytosol; DNA; DNA-Binding Proteins; Gene ...
more infohttps://escholarship.umassmed.edu/faculty_pubs/519/

Biochemical and biophysical characterization of human recombinant IgE-binding protein, an S-type animal lectin<...Biochemical and biophysical characterization of human recombinant IgE-binding protein, an S-type animal lectin<...

IgE-binding protein (εBP) was originally identified by virtue of its affinity for IgE. It is now known to be a β-galactoside- ... abstract = "IgE-binding protein (εBP) was originally identified by virtue of its affinity for IgE. It is now known to be a β- ... N2 - IgE-binding protein (εBP) was originally identified by virtue of its affinity for IgE. It is now known to be a β- ... AB - IgE-binding protein (εBP) was originally identified by virtue of its affinity for IgE. It is now known to be a β- ...
more infohttps://ucdavis.pure.elsevier.com/en/publications/biochemical-and-biophysical-characterization-of-human-recombinant

Oxidative modifications of glyceraldehyde 3-phosphate dehydrogenase regulate metabolic reprogramming of stored red blood cells ...Oxidative modifications of glyceraldehyde 3-phosphate dehydrogenase regulate metabolic reprogramming of stored red blood cells ...

Generation of intermolecular disulfides underlies reversible protein multimerization, a phenomenon observed in oxidative stress ... QconCAT proteins were expressed and purified as previously described.22 Known concentrations of QconCAT proteins were mixed ... Insights into tyrosine phosphorylation control of protein-protein association from the NMR structure of a band 3 peptide ... or structural proteins, such as ankyrin, α/β-spectrin, protein 3.2, or actin, does not affect GAPDH activity.7 In light of ...
more infohttp://www.bloodjournal.org/content/128/12/e32?ijkey=eacfaa458bb55ea453f2910d1a16ecee69c69df9&keytype2=tf_ipsecsha&sso-checked=true

Stress Granules and ALS: A Case of Causation or Correlation? | Springer for Research & DevelopmentStress Granules and ALS: A Case of Causation or Correlation? | Springer for Research & Development

... is a fatal neurodegenerative disease characterized by cytoplasmic protein aggregates within motor neurons. These aggregates are ... Free mRNA in excess upon polysome dissociation is a scaffold for protein multimerization to form stress granules. Nucleic Acids ... Tar DNA binding protein of 43 kDa (TDP-43), 14-3-3 proteins and copper/zinc superoxide dismutase (SOD1) interact to modulate ... Calcium-responsive transactivator (CREST) protein shares a set of structural and functional traits with other proteins ...
more infohttps://rd.springer.com/chapter/10.1007%2F978-3-319-89689-2_7

A human infection with a novel reassortant H3N2 swine virus in ChinaA human infection with a novel reassortant H3N2 swine virus in China

Influenza A matrix protein M1 induces lipid membrane deformation via protein multimerization 2 days ago ...
more infohttp://flu.org.cn/en/article-14651.html

Identification of Novel Functions for Hepatitis C Virus Envelope Glycoprotein E1 in Virus Entry and Assembly | Journal of...Identification of Novel Functions for Hepatitis C Virus Envelope Glycoprotein E1 in Virus Entry and Assembly | Journal of...

Characterization of hepatitis C virus core protein multimerization and membrane envelopment: revelation of a cascade of core- ... 8). These results therefore suggest that the D263A mutation does not drastically affect core protein multimerization. ... HCV core protein quantification.HCV core protein was quantified by a fully automated chemiluminescent microparticle immunoassay ... Oligomerization of hepatitis C virus core protein is crucial for interaction with the cytoplasmic domain of E1 envelope protein ...
more infohttps://jvi.asm.org/content/91/8/e00048-17

Department of Entomology: FacultyDepartment of Entomology: Faculty

2003) The C-Terminus of the Hermes Transposase Contains a Protein Multimerization Domain. Insect Biochem. and Molec. Biol. 33: ... Green fluorescent protein as a genetic marker in transgenic Aedes aegypti. Insect Molec. Biol .9: 1-10. Saville, K. J., W. D. ... Interferon antagonist proteins of influenza and vaccinia viruses are suppressors of RNA silencing. Proc. Natl. Acad. Sci. USA, ... Nuclear Location of the Hermes Transposase Depends on Basic Amino Acid Residues at the N-Terminus of the Protein. Journal of ...
more infohttp://www.entomology.ucr.edu/faculty/atkinson.html

An integrated map of HIV genome-wide variation from a population perspective | Retrovirology | Full TextAn integrated map of HIV genome-wide variation from a population perspective | Retrovirology | Full Text

... in addition to the impact of protein multimerization and immune selective pressure on HIV-1 diversity, HIV-human protein ... We found that amino acid diversity in monomeric proteins was higher than in multimeric proteins, and diversified positions were ... Moreover, intrinsic disorder regions in HIV-1 proteins coincided with high levels of amino acid diversity, facilitating a large ... number of interactions between HIV-1 and human proteins. This first large-scale analysis provided a detailed mapping of HIV ...
more infohttps://retrovirology.biomedcentral.com/articles/10.1186/s12977-015-0148-6