Network compression as a quality measure for protein interaction networks.. Royer L, Reimann M, Stewart AF, Schroeder M.. PLoS ... Combined sequence-based and genetic mapping analysis of complex traits in outbred rats.. Rat Genome Sequencing and Mapping ... Maps for the world of genomic medicine: the 2011 CSHL Personal Genomes meeting.. Zheng-Bradley X, Flicek P.. Hum Mutat. 2012 ... An integrated map of genetic variation from 1,092 human genomes. 1000 Genomes Project Consortium, Abecasis GR, Auton A, Brooks ...
Gotoh H., Miura I. and Wakana S. Genetic mapping of a male factor subfertility locus on mouse chromosome 4. Mammalian Genome ... Hirawatari K., Hanzawa N., Miura I., Wakana S. and Gotoh H. A Cascade of epistatic interactions regulating teratozoospermia in ... Protein-restricted diet during pregnancy after insemination alters behavioral phenotypes of the progeny. Genes & Nutrition 2017 ... Okumura K., Saito M., Isogai E., Miura I., Wakana S., Kominami R. and Wakabayashi Y. Congenic mapping and allele-specific ...
A comprehensive mapping of interactions among Epstein-Barr virus (EBV) proteins and interactions of EBV proteins with human ... a more detailed mapping of their interactions with core herpesvirus proteins, other gamma-specific proteins, and human proteins ... proteome-scale mapping of EBV-EBV and EBV-human direct protein-protein interactions. Such maps represent a rich source of ... Map of the EBV Interactome Network.. To map interactions among EBV proteins, a library or ORFeome of 80 full and 107 partial ...
To map these protein-DNA interactions comprehensively across entire mammalian genomes, we developed a large-scale chromatin ... In vivo protein-DNA interactions connect each transcription factor with its direct targets to form a gene network scaffold. ... However, the protein has eight zinc fingers in its DNA binding domain, and other C2H2 zinc finger proteins such as Zif268 bind ... of which about half mapped to single sites in the human genome (table S1). Sequence reads that map to multiple sites in the ...
This image represents a zoomed region of the Yeast Protein Interaction Map in 3D (VRML) ...
Researchers have produced a detailed map that outlines thousands of physical interactions that take place between proteins ... Researchers have produced a detailed map that outlines thousands of physical interactions that take place between proteins ... From these assays, the scientists identified 2,846 protein-protein interactions, most of which included a protein whose ... Thus, mapping the multitude of interactions among proteins is likely to lead to new insights about drug targets or ...
... to map protein-gene interactions involved in Alzheimers disease. ... Researchers Map Protein-Gene Interactions Involved in Alzheimers Disease By doing so, UC San Diego scientists hope to create a ... Home / Newsroom / Releases / Researchers Map Protein-Gene Interactions Involved in Alzheimers Disease ... The new study combined analyses of gene perturbations and protein interactions, said senior author Robert Rissman, PhD, ...
... data analysis and protein structure modeling. Over the past three years, we have developed tailored experimental methods for ... mass spectrometry and modeling method called MS3D to the structure determination of the rhodopsin-transducin membrane protein ... all steps in the MS3D method for rhodopsin, including protein purification, a functional assay, cross-linking, proteolysis and ... complex (RTC). Herein we describe experimental progress made to adapt the MS3D approach for characterizing membrane protein ...
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Global views of the protein-interaction map. Two global views of protein interaction network are illustrated: a protein class/ ... Confidence scores for protein-protein interactions (A) Drosophila protein-protein interactions have been binned according to ... Global views of the protein-interaction map. (A) Protein family/human disease ortholog view. Proteins are color-coded according ... Statistical properties of the refined Drosophila interaction map. The high-confidence Drosophila protein-protein interactions ...
The study has identified over 2,300 protein interactions. The full dataset and the resulting protein interaction map can be ... By assigning specific functions to cancer-related proteins, this protein-protein interaction map constitutes a first step ... A protein interaction map for a better insight in cancer development. 01.03.2005 ... The number of interactions between proteins is thought to be huge. Exploration of these complex protein networks requires ...
Drug Interaction Knowledge Base Ontology LOOM http://www.biopax.org/release/biopax-level3.owl#Protein Drug Interaction ... http://www.semanticweb.org/ontologies/2010/3/Ontology1271664172453.owl#protein Protein-ligand interaction ontology LOOM ... Create New Mapping Delete. Mapping To. Ontology. Source. http://www.bioassayontology.org/bao#BAO_0000175 BioAssay Ontology LOOM ... http://psink.de/scio/Protein Spinal Cord Injury Ontology LOOM http://purl.obolibrary.org/obo/MI_0326 Molecular Interactions ...
The interaction networks presented here provide a set of hypothesis for further experimental investigation into the DENV life ... Dengue virus manipulates cellular processes to its advantage through specific interactions with the hosts protein interaction ... Mapping protein interactions between Dengue virus and its human and insect hosts PLoS Negl Trop Dis. 2011 Feb 15;5(2):e954. doi ... Protein-protein interactions between the virus and its host are one avenue through which dengue can connect and exploit these ...
Towards a proteome-scale map of the human protein-protein interaction network. Nature 437 ... Towards a proteome-scale map of the human protein-protein interaction network. Nature 437 (2005) by J F Rual, K Venkatesan, T ... In the network querying problem, one is given a protein complex or pathway of species A and a protein-protein interaction ... In the network querying problem, one is given a protein complex or pathway of species A and a protein-protein interaction ...
Mapping the Nonstructural Protein Interaction Network of Porcine Reproductive and Respiratory Syndrome Virus. Jiangwei Song, ... Mapping the Nonstructural Protein Interaction Network of Porcine Reproductive and Respiratory Syndrome Virus ... Mapping the Nonstructural Protein Interaction Network of Porcine Reproductive and Respiratory Syndrome Virus ... Mapping the Nonstructural Protein Interaction Network of Porcine Reproductive and Respiratory Syndrome Virus ...
Toward a protein-protein interaction map of the budding yeast: A comprehensive system to examine two-hybrid interactions in all ... Toward a protein-protein interaction map of the budding yeast: A comprehensive system to examine two-hybrid interactions in all ... Toward a protein-protein interaction map of the budding yeast: A comprehensive system to examine two-hybrid interactions in all ... Toward a protein-protein interaction map of the budding yeast: A comprehensive system to examine two-hybrid interactions in all ...
Protein-protein interactions in the yeast pheromone response pathway: Ste5p interacts with all members of the MAP kinase ... Ste5p, a protein of unknown biochemical function, interacted with protein kinases that operate at each step of the MAP kinase ... We have used the two-hybrid system of Fields and Song to identify protein-protein interactions that occur in the pheromone ... All of the interactions we detected involved at least one member of the MAP kinase cascade that is a central element of the ...
Further investigation of these predicted protein-protein interactions should provide targets to combat the clinical ... In this work, we used a computational method based on protein structures to predict interactions between DENV and its human and ... proteins encoded by DENV must interact with and alter the behavior of protein networks in both of these hosts. ... We predict numerous interactions, with many involved in known cell death, stress, and immune system pathways. ...
C-reactive protein. AAIM. antibody-array interaction mapping. KNG. kininogen. SAP. serum amyloid P component. Bis-Tris. 2-[bis( ... Antibody-Array Interaction Mapping, a New Method to Detect Protein Complexes Applied to the Discovery and Study of Serum ... Antibody-Array Interaction Mapping, a New Method to Detect Protein Complexes Applied to the Discovery and Study of Serum ... Antibody-Array Interaction Mapping, a New Method to Detect Protein Complexes Applied to the Discovery and Study of Serum ...
... chemical shift mapping and 15N NMR relaxation studies. ... Interactions of human nucleotide excision repair protein XPA ... INTERACTIONS OF HUMAN NUCLEOTIDE EXCISION REPAIR PROTEIN XPA WITH RPA70 AND DNA: CHEMICAL SHIFT MAPPING AND 15N NMR RELAXATION ... Pre-calculated protein structure alignments at the RCSB PDB website. Bioinformatics 26: 2983-2985 ...
Protein-protein interactions in the yeast pheromone response pathway: Ste5p interacts with all members of the MAP kinase ... Protein-protein interactions in the yeast pheromone response pathway: Ste5p interacts with all members of the MAP kinase ... Protein-protein interactions in the yeast pheromone response pathway: Ste5p interacts with all members of the MAP kinase ... Protein-protein interactions in the yeast pheromone response pathway: Ste5p interacts with all members of the MAP kinase ...
Studies into interactions between MAP kinase and MAP kinase kinase proteins of Arabidopsis ... In this study, the yeast two -hybrid system was used to identify protein-protein interactions between all Arabidopsis MAPKs and ... The Arabidopsis thaliana genome contains genes encoding 10 MAP kinase kinase (MKK) and 20 Map kinase (MAPK) proteins, however ... the result from the qualitative β-galactosidase filter assay showed that 6 MAPK proteins interacted with 6 MKK proteins. ...
Self-Association and Mapping of the Interaction Domain of Hepatitis E Virus ORF3 Protein. Shweta Tyagi, Shahid Jameel, Sunil K ... Self-Association and Mapping of the Interaction Domain of Hepatitis E Virus ORF3 Protein ... Self-Association and Mapping of the Interaction Domain of Hepatitis E Virus ORF3 Protein ... Self-Association and Mapping of the Interaction Domain of Hepatitis E Virus ORF3 Protein ...
Coupled with next generation sequencing, ChIP-seq experiments map protein-DNA... ... is the most widely used method to analyze protein-DNA interactions in vivo. ... Johnson DS, Mortazavi A, Myers RM, Wold B (2007) Genome-wide mapping of in vivo protein-DNA interactions. Science 316:1497-1502 ... Xu C., Corces V.G. (2018) Genome-Wide Mapping of Protein-DNA Interactions on Nascent Chromatin. In: Vavouri T., Peinado M. (eds ...
Systematic protein-protein interaction mapping for clinically relevant human GPCRs. Kate Sokolina, Saranya Kittanakom, Jamie ... Moonlighting proteins and proteinprotein interactions as neurotherapeutic targets in the G protein‐coupled receptor field. ... Snider J, Kotlyar M, Saraon P, Yao Z, Jurisica I, Stagljar I (2015) Fundamentals of protein interaction network mapping. Mol ... Hamdan FF, Percherancier Y, Breton B, Bouvier M (2006) Monitoring proteinprotein interactions in living cells by ...