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*  Scheraga Group Homepage
... and empirical energy calculations to determine the stable conformations of proteins, polypeptides, enzyme-substrate complexes, ... protein-protein interactions, nucleic acids, protein-nucleic acid interactions, and the pathways and thermodynamics of folding ... dictate the folding of a polypeptide chain in water into the three-dimensional structure of a native protein and (b) determine ... in studies of the pathways of protein folding, and the mechanism of action of thrombin on fibrinogen (an important reaction in ...
http://www.scheraga.chem.cornell.edu
*  Optical rotatory dispersion: applications to organic chemistry - Carl Djerassi - Google Books
... peak persion plain dispersion curves polarized polypeptides positive Cotton effect proline proteins random conformation RD ...
https://books.google.co.in/books/about/Optical_rotatory_dispersion.html?id=0UNRAAAAMAAJ&hl=en
*  Protein Conformation | Life Sciences | Subjects | Wiley
Derek J. Chadwick and Kate Widdows are editors for Protein Conformation and other scientific titles. ... protein engineering and molecular modeling offer provocative insights into current views on the protein folding problem and ... Comparative Analysis of Protein Three-Dimensional Structures and an Approach to the Inverse Folding Problem (T. Blundell). ... How the amino acid sequence of a protein determines its three-dimensional structure is a major problem in biology and chemistry ...
https://www.wiley.com/en-us/Protein+Conformation-p-9780470514153
*  Stabilization Energies of Protein Conformation | SpringerLink
The study of protein stability is currently undergoing a dramatic change. Early work, especially after Kauzmann (1959), ... In: Fasman G.D. (eds) Prediction of Protein Structure and the Principles of Protein Conformation. Springer, Boston, MA. * DOI ... Prediction of Protein Structure and the Principles of Protein Conformation pp 161-192 , Cite as ... Amino Acid Substitution Cross Link Protein Stability Stabilization Energy Protein Conformation These keywords were added by ...
https://link.springer.com/chapter/10.1007/978-1-4613-1571-1_5
*  Protein Conformation | School of Pharmacy | UCSF
Research in my lab focuses on atomic-level mechanisms of protein regulation, protein-ligand interactions, and computer-aided ... I am interested in the structure, function, and evolution of proteins and their assemblies. As Associate Dean of Research, I ... DeGrado receives Protein Society's Stein and Moore Award. Wed Feb 11, 2015 ... The award is given annually by the international society "to recognize eminent leaders in protein science who have made ...
https://pharmacy.ucsf.edu/keywords/protein-conformation
*  Understanding Enzymes: Protein Conformation Coupled Catalysis
The role of conformational changes in enzyme catalysis will be discussed. A model will be advanced consisting of conformational ensembles and multiple reaction pathways to explain the incredible catalytic efficiency of enzymes. The results of ensemble and single-molecule experiments obtained with dihydrofolate reductase will be presented that support this model ...
https://smartech.gatech.edu/handle/1853/32761
*  Using the Malvern Zetasizer Nano for Protein Conformation Studies
... News Nov 14, 2006 ... The Zetasizer Nano is a protein characterization tool. Offering sensitivity it is designed to allow protein molecules with a ... Protein structure correlates closely with function and is a parameter of significant interest. Using DLS, conformational ... and can also be used to measure the affinity of carbohydrate binding proteins, such as Lectin, with monosaccharides. ...
https://www.technologynetworks.com/analysis/news/using-the-malvern-zetasizer-nano-for-protein-conformation-studies-213219
*  Protein - Conformation of proteins in interfaces | Britannica.com
Conformation of proteins in interfaces: Like many other substances with both hydrophilic and hydrophobic groups, soluble ... Proteins, when forming an interfacial film, are present as a monomolecular layer-i.e., a layer one molecule in height. Although ... Within the interface, proteins spread, forming thin films. Measurements of the surface tension, or interfacial tension, of such ... proteins tend to migrate into the interface between air and water or oil and water; the term oil here means a hydrophobic ...
https://www.britannica.com/science/protein/Conformation-of-proteins-in-interfaces
*  Maintaining and Enhancing Diversity of Sampled Protein Conformations in Robotics-Inspired Methods
... ... Our results show a significant increase in the diversity of the conformations sampled for proteins consisting of up to 500 ... The ability to efficiently sample structurally diverse protein conformations allows one to gain a high-level view of a ... Abella, Jayvee R., Moll, Mark and Kavraki, Lydia E.. "Maintaining and Enhancing Diversity of Sampled Protein Conformations in ...
https://scholarship.rice.edu/handle/1911/102294
*  Detecting intermediate protein conformations using algebraic topology | BMC Bioinformatics | Full Text
At every iteration a parent protein conformation is chosen from the conformation pool, then a rotatable bond between two C- α ... For each selected protein, the C- α based representation of the start and target points are used to obtain the conformations ... Therefore, the search space made out of all possible conformations that a protein can assume is large and its enumeration is ... Shehu A, Olson B. Guiding the search for native-like protein conformations with an ab-initio tree-based exploration. Int J ...
https://bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-017-1918-z
*  Albumin-coated SPIONs: an experimental and theoretical evaluation of protein conformation, binding affinity and competition...
... an experimental and theoretical evaluation of protein conformation, binding affinity and competition with serum proteins. ... an experimental and theoretical evaluation of protein conformation, binding affinity and competition with serum proteins ... Proteins are commonly the first biomolecules that NPs encounter when they interact with biological systems either in vitroor in ... We believe that a complete understanding of the behavior and morphology of BSA-SPIONs and how the protein interacts with SPIONs ...
http://icmab.es/albumin-coated-spions-an-experimental-and-theoretical-evaluation-of-protein-conformation-binding-affinity-and-competition-with-serum-proteins
*  Lack of complex N glycans on HIV 1 envelope glycoproteins preserves protein conformation and entry function - IAVI -...
Title: Lack of complex N glycans on HIV 1 envelope glycoproteins preserves protein conformation and entry function Abstract: ... The folding and conformation of Env proteins was little affected by the manipulation of the glycosylation. Viruses produced in ... Lack of complex N-glycans on HIV-1 envelope glycoproteins preserves protein conformation and entry function. Virology 2010;401( ... Lack of complex N glycans on HIV 1 envelope glycoproteins preserves protein conformation and entry function ...
https://www.iavi.org/newsroom/iavi-partner-scientific-publications/lack-of-complex-n-glycans-on-hiv-1-envelope-glycoproteins-preserves-protein-conformation-and-entry-function
*  Gas-phase hydrogen/deuterium exchange in a travelling wave ion guide for the examination of protein conformations
We conclude that HDX of protein ions in a TWIG is highly sensitive to protein conformation, enables the detection of conformers ... Accumulating evidence suggests that solution-phase conformations of small globular proteins and large molecular protein ... protein charge state) influence part a, the gas-phase conformation of the protein influence part b. ... The conformations revealed in these short times should better reflect the conformational landscape of protein ions at the ...
http://pubmedcentralcanada.ca/pmcc/articles/PMC2794942/
*  "Protein conformation in a vaccine matters" by Trudy G. Morrison
Our results demonstrate that the conformation of antigens in VLPs is of critical importance for optimal stimulation of ... protein conformation, respiratory syncytial virus, vaccine, fusion protein ... Morrison, Trudy G., "Protein conformation in a vaccine matters" (2015). Open Access Articles. 2612. https://escholarship. ... Our results demonstrate that the conformation of antigens in VLPs is of critical importance for optimal stimulation of ...
https://escholarship.umassmed.edu/oapubs/2612/
*  Knowledge-based prediction of protein backbone conformation using a structural alphabet
Predicting the local structure of a protein in terms of protein blocks is the general objective of this work. A new approach, ... This form of analyzing proteins involves drafting its structure as a string of Protein Blocks. ... to scan this database and predict most probable backbone conformations for the protein local structures. Though PB-kPRED uses ... One such library, Protein Blocks, is composed of 16 standard 5-residues long structural prototypes. ...
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0186215
*  PSP - Protein Structure Prediction (protein 3D conformation prediction at rest) | AcronymFinder
... protein 3D conformation prediction at rest). PSP is defined as Protein Structure Prediction (protein 3D conformation prediction ... protein 3D conformation prediction at rest) abbreviated? PSP stands for Protein Structure Prediction ( ... PSP stands for Protein Structure Prediction (protein 3D conformation prediction at rest). ... Protein structure prediction, 2d ed. To that end, this reference sheds light on the methods used for protein structure ...
https://www.acronymfinder.com/Protein-Structure-Prediction-
*  Publication | Laboratory for Protein Conformation Diseases | RIKEN
An infectious conformation compatible with two highly divergent yeast prion proteins. Cell 121, 49-62 (2005). ... Tanaka, M. A protein transformation protocol for introducing yeast prion particles into yeast. Methods in Enzymology (Guide to ... Nekooki-Machida, Y., Kurosawa, M., Nukina, N., Ito, K., Oda, T., and Tanaka, M. Distinct conformations of in vitro and in vivo ... Ohhashi, Y., Ito, K., Toyama, B.H., Weissman, J.S., and Tanaka M. Differences in prion strain conformations result from non- ...
http://www.motomasalab.brain.riken.jp/pub_eng.html
*  Freeze-Quench Study on Protein Conformation State - Elka Georgieva
... it is not well understood to what extent protein conformations represented by these distributions correspond to conformations ... Freeze-Quench Study on Protein Conformation State Georgieva, Elka R. Cornell University, Ithaca, NY, United States ... However, for a folded protein or a protein complex the picture may be more complex, since many bonds allow for substantial ... proteins. Similar arguments, such as protein confinement by the crystal lattice and using cryogenic temperatures for collecting ...
http://grantome.com/grant/NIH/P41-RR016292-11-8171
*  HDX Solution - HDX Solution - unlock insights in protein structure conformation | Bruker
The Bruker HDX Solution enables you to answer these questions and unlock insights into protein structure conformation, ... Do you want to understand more about the protein-ligand (drug/protein) interactions and their relationship to drug activity? ... monitor protein/protein-drug interactions and perform epitope mapping. In recent years Hydrogen Deuterium Exchange Mass ... technique within the arsenal of analytical tools available for providing such insights into protein structure conformation. ...
https://www.bruker.com/it/products/mass-spectrometry-and-separations/hdx-solution/overview.html
*  RCSB PDB - 1A13: G PROTEIN-BOUND CONFORMATION OF MASTOPARAN-X, NMR, 14 STRUCTURES Methods Report Page
G protein-bound conformation of mastoparan-X: heteronuclear multidimensional transferred nuclear overhauser effect analysis of ...
http://www.rcsb.org/pdb/explore/materialsAndMethods.do?structureId=1A13
*  Significance of bound water to local chain conformations in protein crystals | PNAS
Significance of bound water to local chain conformations in protein crystals Message Subject (Your Name) has sent you a message ... Significance of bound water to local chain conformations in protein crystals. C H Robert and P S Ho ... The fractional water occupancy of each was found by comparison of the total number of conformations in the database regardless ... We examine how the polypeptide chain in protein crystal structures exploits the multivalent hydrogen-bonding potential of bound ...
https://www.pnas.org/content/92/16/7600
*  Protofold: A Successive Kinetostatic Compliance Method for Protein Conformation Prediction | Journal of Mechanical Design |...
Protofold: A Successive Kinetostatic Compliance Method for Protein Conformation Prediction Kazem Kazerounian, Khalid Latif and ... Kazerounian K, Latif K, Alvarado C. Protofold: A Successive Kinetostatic Compliance Method for Protein Conformation Prediction ... Return to: Protofold: A Successive Kinetostatic Compliance Method for Protein Conformation Prediction ... the final conformation of the protein. This methodology is implemented in a computer software package named PROTOFOLD . In this ...
http://mechanicaldesign.asmedigitalcollection.asme.org/article.aspx?articleid=1448578
*  A particularly labile Asp-Pro bond in the green mamba muscarinic toxin MTX2. Effect of protein conformation on the rate of...
Modelling studies indicate that the native toxin conformation can catalyse the Asp53-Pro54 bond cleavage. The implications of ... may irreversibly affect the structural integrity of Asp-Pro containing peptides and proteins. ... Effect of protein conformation on the rate of cleavage.}, author={I S{\'e}galas and Robert Thai and Ren{\'e}e M{\'e}nez and ... Effect of protein conformation on the rate of cleavage.. @article{Sgalas1995APL, title={A particularly labile Asp-Pro bond in ...
https://www.semanticscholar.org/paper/A-particularly-labile-Asp-Pro-bond-in-the-green-of-S%C3%A9galas-Thai/47dc368a88c3e5cd08f3ba4202898cddeed37ca0
*  Lysine Acetylation Controls Local Protein Conformation by Influencing Proline Isomerization - Oxford Neuroscience
trans conformation and reduces K4me3. Environmental stress-induced genes are most sensitive to the changes atK14 influencing H3 ... tail conformation and K4me3. By contrast, ribosomal protein genes maintain K4me3, required for their repression during stress, ... Lysine Acetylation Controls Local Protein Conformation by Influencing Proline Isomerization Howe FS., Boubriak I., Sale MJ., ... trans conformation and reduces K4me3. Environmental stress-induced genes are most sensitive to the changes atK14 influencing H3 ...
https://www.neuroscience.ox.ac.uk/publications/506203
*  Effects of Protein Conformation in Docking: Improved Pose Prediction Through Protein Pocket Adaptation - Certara
Computational methods for docking ligands have been shown to be remarkably dependent on precise protein conformation, where ... Effects of Protein Conformation in Docking: Improved Pose Prediction Through Protein Pocket Adaptation. ...
https://www.certara.com/citations/effects-of-protein-conformation-in-docking-improved-pose-prediction-through-protein-pocket-adaptation/