ALAD is a zinc-binding protein which is important in the biosynthesis of heme, the co-factor found in hemoglobin. Lead ...

This seems to be at odds with the requirement of amino acids for protein biosynthesis in rapidly growing tumor cells; raising ... We recently discovered that the stress granule protein G3BP1 (Ras GTPase-activating protein-binding protein 1) anchors the TSC ... The tuberous sclerosis protein (TSC) complex acts as a relay for anabolic signaling and as a tumor suppressor. These functions ... Alexander Martin Heberle: "A stress granule protein integrates metabolic signals and controls lysosomal TSC recruitment and ...

This is a "connection" page, showing publications James Liao has written about Protein Biosynthesis. ...

Effects of modification in lysate preparation on protein composition and biosynthesis activity. Schindler PT, Baumann S, Reuss ... Protein kinase C alpha-dependent phosphorylation of golgi proteins. Radau B, Otto A, Muller EC, Westermann P. ... "Early" protein synthesis of Lactobacillus delbrueckii ssp bulgaricus in milk revealed by [S-35]methionine labeling and two- ... Identification of platelet proteins separated by two-dimensional gel electrophoresis and analyzed by matrix assisted laser ...

... which is critical for the translational initiation and elongation steps of protein biosynthesis. The team observed that in the ... Mutated worms showed protein accumulation via the unfolded protein response (UPR) pathway and subsequent ER stress.5 ... stress and downregulation of protein biosynthesis in peripheral tissues trigger pathways that induce sleep. ... Since sleep loss causes ER stress6 and impairs protein synthesis,7 Kawano and his colleagues believe that organisms cope with ...

JASSY - a Chloroplast Outer Membrane Protein Required for Jasmonate Biosynthesis. (2019) Guan L., Denkert N., Eisa A., Lehmann ... Cooperativity of membrane‑protein and protein-protein interactions control membrane remodeling by epsin 1 and affects clathrin‑ ... He could show that the membrane remodeling activity of the ENTH domain of epsin1 is regulated by protein-protein and protein- ... Specifically, we use recombinantly expressed proteins and purified native protein complexes in combination with a wide variety ...

... biosynthesis of cellulose, photosynthesis, protein ubiquitination, stress responses, and retroposition. Expression analysis ... Multi-environment field trials were conducted to evaluate the grain Zn, Fe and protein concentration of 32 bread wheat ( ... When the stress occurred during grain filling, seed dry weight decreased, and protein and total fatty acid concentrations ...

... dissecting the mechanism of coupling light-harvesting chlorophyll-binding protein transport and chlorophyll biosynthesis, ... including uncovering the regulatory mechanism orchestrating chloroplast protein translation and chlorophyll biosynthesis, ... He has made conceptual breakthrough that defines the roles of host lipogenic modulator SREBP and trafficking protein AP2M1 for ... Project Title: Control of chloroplast protein homeostasis. Dr Wang intends to focus on the molecular mechanisms underlying the ...

Here we identify Heterochromatin Protein 1β (HP1β) as an essential protein for proper differentiation, and, unexpectedly, for ... Recently, several chromatin-related proteins have been shown to regulate ESC pluripotency and/or differentiation, yet the role ... epigenetic signatures enriched for active chromatin marks and hyperdynamic binding of structural chromatin proteins. ... of the major heterochromatin proteins in pluripotency is unknown. ...

We show that ER membrane localisation for TAA/YUC proteins involved in auxin biosynthesis is already present early on in the ... Protein biochemistry and membrane targeting including protein-protein interactions, protein-membrane interactions, protein ... It was suggested that RTN proteins form protein complexes with proteins in the PD plasma membrane and desmotubule to stabilize ... and can therefore give information on protein-protein interactions as well as the membrane topology of the tested protein. ...

... biosynthesis of proteins) after acquiring its sequence of nucleotides from the latter during transcription (i.e. copying of DNA ... They will provide for powerful approaches in terms of probing protein function and structure both in vitro and in vivo. ... However, they are functionally compatible with all components of the cellular machinery required to make proteins. ... UAAs have been cotranslationally incorporated into proteins that have high efficiency and fidelity. The resulting incorporated ...

Identity and function of an essential nitrogen ligand of the nitrogenase cofactor biosynthesis protein NifB. Nature ... A second approach is to generate tools to study the enzyme that can help guide our understanding of the biological proteins. ... Our primary goal is to understand how the protein environment guides the reaction path, from generating a primary carbon ... We are interested in how the protein environment tunes the molybdenum center through direct ligation to the molybdenum or ...

Using Western blotting and/or radioimmunoprecipitation analysis, the biosynthesis and metabolism of viral surface protein may ... Using Western blotting and/or radioimmunoprecipitation analysis, the biosynthesis and metabolism of viral surface protein may ... The antibody immunoprecipitates gp46 surface protein from radiolabeled cell lysates, as well as viral precursor protein. ... No reactivity with the surface protein of HTLV-II (MoT) has been observed. The antibody is of the IgG1 subclass and has been ...

I am using computational protein design to create novel enzymes for the biosynthesis of modified natural product molecules. To ... Proteins are some of the most important functional units in our cells. To make proteins, our cells turn on genes (these are ... In humans, the homolog of SUT-2 protein is MSUT2. MSUT2, an RNA binding protein, is abundant in neurons and correlates with an ... Protein engineers have successfully built proteins with diverse shapes and molecular properties. But they are typically ...

... it has the highest batch protein biosynthesis yields, with up to 2.3 mg/mL reported for a model green fluorescent protein ( ... Protein glycosylation, or the attachment of sugar moieties (glycans) to proteins, is important for protein stability, activity ... have shown that fusing integral membrane proteins to MSP can be used to produce soluble, active membrane proteins (Mizrachi et ... After the reaction was complete, soluble proteins were separated by centrifugation at 20,000xg for 10 min at 4ºC. Proteins were ...

It is postulated that these proteins control the biosynthesis of potent mediators of inflammation such as prostaglandins and ... However, corticosteroids are thought to act by the induction of phospholipase A2 inhibitory proteins, collectively called ...

... dependent proteins in these families. While prevalent in mycobacteria, markers of F(420) biosynthesis appeared to be absent ... biosynthesis nominated many actinobacterial proteins as candidate F(420)-dependent enzymes. Three such families dominated the ... This dependence and the cofactors rarity may make F(420)-related proteins promising drug targets. ...

... protein synthesis, and the abundance of mRNA involved in polyamine biosynthesis, proliferation, and protein synthesis in C2C12 ... Polyamines increased (p , 0.05) the abundance of mRNA involved in polyamine biosynthesis, proliferation, and protein synthesis ... The cell type had no effect (p , 0.10) on proliferation, protein synthesis, or mRNA abundance at any time point. Each treatment ... Overall, C2C12 and Sol8 myoblasts do not differ (p , 0.10) in proliferation, protein synthesis, or mRNA abundance at the time ...

While parts of them may be similar to the proteins reportedly involved in solvent stress response in other Gram-positive ... Disruption of the particular genes in proline biosynthesis pathways clarified the essential role of the anabolic ProB-ProA-ProI ... Molecular modifications to increase gene dosage for proline biosynthesis as well as for glutamate acquisition enhanced butanol ... 108 butanol-responsive proteins were revealed, and classified into seven groups according to their biological functions. ...

It exerts its antimicrobial effect by blocking 2 consecutive steps in the biosynthesis of the nucleic acids and proteins ...

Protein Biosynthesis Biochemistry, Genetics and Molecular Biology 63% * Mitochondrion Biochemistry, Genetics and Molecular ... Biochemistry, PhD, Visualisation of RNA-protein interactions in living cells, University of Otago ...

A correction has been published: Persisting Enhanced Proinsulin-insulin and Protein Biosynthesis (3H-Leucine Incorporation) by ...

The ribosome is a complex molecular machine which plays an essential role in protein biosynthesis across all domains of life. ... They were successfully applied to study the Hsp90 chaperone protein and to several protein-protein and protein-peptide systems ... proteins constantly bump into other proteins which sometimes leads to biologically meaningful contact of the two proteins-the ... The process of protein-protein complex formation is of fundamental importance for a better understanding of a variety of ...

Since both genes are predicted to be involved in lipopolysaccharide (LPS) biosynthesis, flagellum assembly, or protein ... Recent studies on the functions of I/R-activated kinases, such as p38 mitogen-activated protein kinase (MAPK), showed that I/R ... Suitable for use with native or denaturation protocols, with no degradation of protein. This kit has been assembled to contain ... Alterations in oxidative phosphorylation complex proteins in the hearts of transgenic mice that overexpress the p38 MAP kinase ...

Protein Folding, Recombinant Proteins/biosynthesis, Spectrometry, Mass, Electrospray Ionization, Spectrometry, Mass, Matrix- ... Tissue Inhibitor of Metalloproteinases/biosynthesis, alpha-Macroglobulins/chemistry", ...

Recombinant Proteins/biosynthesis, Secretory Pathway/genetics",. author = "Browning, {Douglas F} and Richards, {Kirsty L} and ... Numerous high-value proteins are secreted into the Escherichia coli periplasm by the General Secretory (Sec) pathway, but Sec- ... A second target protein, an scFv, is also shown to be exported at much higher rates in TatExpress strains. ... A second target protein, an scFv, is also shown to be exported at much higher rates in TatExpress strains.", ...

Protein Catabolism 14% * Protein Biosynthesis 14% * Hormone Blood Level 14% * Liquid 14% ...