JCI -
SHARPIN-mediated regulation of protein arginine methyltransferase 5 controls melanoma growth  JCI - SHARPIN-mediated regulation of protein arginine methyltransferase 5 controls melanoma growth
... a type II protein arginine methyltransferase, and increased its multiprotein complex and methyltransferase activity. Activated ... PRMT5 controlled the expression of the transcription factors SOX10 and MITF by SHARPIN-dependent arginine dimethylation and ...
more infohttps://www.jci.org/articles/view/95410/pdf
HSL7 - Protein arginine N-methyltransferase HSL7 - Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Bakers yeast) - HSL7...  HSL7 - Protein arginine N-methyltransferase HSL7 - Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) - HSL7...
... dimethylation of the guanidino nitrogens of arginine residues in target proteins (PubMed:18515076). Involved in the control of ... S-adenosyl-L-methionine-dependent protein-arginine N-methyltransferase that can catalyze both the mono- and symmetric (type II ... Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.PROSITE- ... Protein arginine N-methyltransferase HSL7Add BLAST. 827. Amino acid modifications. Feature key. Position(s). DescriptionActions ...
more infohttp://www.uniprot.org/uniprot/P38274
ENZYME: 2.-.-.  ENZYME: 2.-.-.
Type I protein arginine methyltransferase 2.1.1.320 Type II protein arginine methyltransferase 2.1.1.321 Type III protein ... arginine methyltransferase 2.1.1.322 Type IV protein arginine methyltransferase 2.1.1.323 (-)-pluviatolide 4-O- ... Protein-histidine pros-kinase 2.7.13.2 Protein-histidine tele-kinase 2.7.13.3 Histidine kinase 2.7.14.1 Protein arginine kinase ... O-methyltransferase 2.1.1.76 Quercetin 3-O-methyltransferase 2.1.1.77 Protein-L-isoaspartate(D-aspartate) O-methyltransferase ...
more infohttps://enzyme.expasy.org/EC/2.-.-.-
Phenylethanolamine N-methyltransferase - wikidoc  Phenylethanolamine N-methyltransferase - wikidoc
arginine→glutamate. Ornithine aminotransferase - Ornithine decarboxylase - Agmatinase. glutamate→alpha-ketoglutarate→TCA. ... Protein pages needing a picture. *Genes on chromosome 17. *Pages with broken file links ... 2.1.1 - Methyltransferases. 5-hydroxyindole-O-methyltransferase/Acetylserotonin O-methyltransferase - Betaine-homocysteine ... methyltransferase - Catechol-O-methyl transferase - Histamine N-methyltransferase - Homocysteine methyltransferase - 5- ...
more infohttp://wikidoc.org/index.php/Phenylethanolamine_N-methyltransferase
Protein Arginine Methyltransferases (PRMTs)  Protein Arginine Methyltransferases (PRMTs)
... recombinant proteins & enzymes, and other innovative research tools for studying Apoptosis, Metabolism, Cell Proliferation, ... Categories: Protein Arginine Methyltransferases (PRMTs) *DNA Methyltransferases (DNMTs)(45)*Antibodies & Blocking Peptides(30) ... BioVision develops and offers a wide variety of products including assay kits, antibodies, recombinant proteins & enzymes, and ...
more infohttps://www.biovision.com/products/epigenetics/writer-enzymes/protein-arginine-methyltransferases-prmts.html
Structural biology and chemistry of protein arginine methyltransferases - MedChemComm (RSC Publishing)  Structural biology and chemistry of protein arginine methyltransferases - MedChemComm (RSC Publishing)
Protein arginine methyltransferases (PRMTs), an emerging target class in drug discovery, can methylate histones and other ... Structural biology and chemistry of protein arginine methyltransferases M. Schapira and R. Ferreira de Freitas, Med. Chem. ... Protein arginine methyltransferases (PRMTs), an emerging target class in drug discovery, can methylate histones and other ... we review the growing body of structural information characterizing this protein family, including structures in complex with ...
more infohttps://pubs.rsc.org/en/content/articlelanding/2014/MD/C4MD00269E
Protein arginine methyltransferase 5 - Wikipedia  Protein arginine methyltransferase 5 - Wikipedia
"Entrez Gene: PRMT5 protein arginine methyltransferase 5". Kim S, Gunesdogan, U, Zylicz JJ, Hackett, JA, Cougot, D, Bao, S, Lee ... Protein arginine N-methyltransferase 5 is an enzyme that in humans is encoded by the PRMT5 gene. PRMT5 symmetrically ... Protein arginine methyltransferase 5 has been shown to interact with: CLNS1A, Janus kinase 2, SNRPD3, SUPT5H, and WD repeat- ... protein arginine methyltransferases, and tubulins alpha 3 and beta 1 that is independent of its association with preribosomal ...
more infohttps://en.wikipedia.org/wiki/Protein_arginine_methyltransferase_5
Exercise-induced Protein Arginine Methyltransferase Expression in Skeletal Muscle  Exercise-induced Protein Arginine Methyltransferase Expression in Skeletal Muscle
This study aimed to determine protein arginine methyltransferase 1 (PRMT1), -4 (also known as coactivator-associated arginine ... Acute physical activity also augmented (P < 0.05) the targeted methyltransferase activities of the PRMT in the myonuclear ... Despite the significant activation of canonical exercise-induced signaling involving AMP-activated protein kinase and ... methyltransferase 1 [CARM1]), and -5 expression and function during acute, exercise-induced skeletal muscle remodeling in vivo. ...
more infohttps://insights.ovid.com/pubmed?PMID=29112628
The protein arginine methyltransferase PRMT5 promotes D2-like dopamine receptor signaling | Science Signaling  The protein arginine methyltransferase PRMT5 promotes D2-like dopamine receptor signaling | Science Signaling
Protein arginine methylation is catalyzed by a family of enzymes termed protein arginine methyltransferases (PRMTs) (21). The ... were methylated by protein arginine methyltransferase 5 (PRMT5). By mutating these arginine residues, we further showed that ... The protein arginine methyltransferase PRMT5 promotes D2-like dopamine receptor signaling Message Subject. (Your Name) has ... The protein arginine methyltransferase PRMT5 promotes D2-like dopamine receptor signaling. By Neah Likhite, Christopher A. ...
more infohttp://stke.sciencemag.org/content/8/402/ra115
Protein arginine methyltransferase 1 promoted the growth and migration of cancer cells in esophageal squamous cell carcinoma |...  Protein arginine methyltransferase 1 promoted the growth and migration of cancer cells in esophageal squamous cell carcinoma |...
Dysregulation of protein arginine methyltransferase 1 (PRMT1) has been reported in several cancer types. However, its ... Colon cancer and protein arginine methyltransferase 1 gene expression. Anticancer Res. 2009;29:1361-6.PubMedGoogle Scholar ... The protein arginine methyltransferases CARM1 and PRMT1 cooperate in gene regulation. Nucleic Acids Res. 2008;36:3202-13. ... Protein arginine methyltransferase 1 promoted the growth and migration of cancer cells in esophageal squamous cell carcinoma. ...
more infohttps://link.springer.com/article/10.1007/s13277-015-4098-3
Loss of Protein Arginine Methyltransferase 8 Alters Synapse Composition and Function, Resulting in Behavioral Defects | Journal...  Loss of Protein Arginine Methyltransferase 8 Alters Synapse Composition and Function, Resulting in Behavioral Defects | Journal...
2008) Identification of proteins interacting with protein arginine methyltransferase 8: the Ewing sarcoma (EWS) protein binds ... Here we use mice lacking protein arginine methyltransferase 8 (PRMT8) in the brain to examine how loss of this protein affects ... The multifunctional protein arginine methyltransferase 8 (PRMT8) possesses both methyltransferase and phospholipase activities ... 2007) Specific regional distribution of protein arginine methyltransferase 8 (PRMT8) in the mouse brain. Brain Res 1155:1-9. ...
more infohttp://www.jneurosci.org/content/37/36/8655?rss=1
Abstract 3809: Protein arginine methyltransferase 1 (PRMT1) is a candidate therapeutic target for breast cancers | Cancer...  Abstract 3809: Protein arginine methyltransferase 1 (PRMT1) is a candidate therapeutic target for breast cancers | Cancer...
... we found that Protein Arginine Methyltransferase 1 (PRMT1) is overexpressed in TNBC at the mRNA level. At the protein level, ... Abstract 3809: Protein arginine methyltransferase 1 (PRMT1) is a candidate therapeutic target for breast cancers. David ... Protein arginine methyltransferase 1 (PRMT1) is a candidate therapeutic target for breast cancers. [abstract]. In: Proceedings ... Abstract 3809: Protein arginine methyltransferase 1 (PRMT1) is a candidate therapeutic target for breast cancers ...
more infohttp://cancerres.aacrjournals.org/content/76/14_Supplement/3809
Antibodies & Blocking Peptides - Protein Arginine Methyltransferases (PRMTs) - Writer Enzymes - Epigenetic Regulation - Cancer...  Antibodies & Blocking Peptides - Protein Arginine Methyltransferases (PRMTs) - Writer Enzymes - Epigenetic Regulation - Cancer...
... recombinant proteins & enzymes, and other innovative research tools for studying Apoptosis, Metabolism, Cell Proliferation, ... BioVision develops and offers a wide variety of products including assay kits, antibodies, recombinant proteins & enzymes, and ...
more infohttps://www.biovision.com/products/cancer-research/epigenetic-regulation/writer-enzymes/protein-arginine-methyltransferases-prmts/antibodies-blocking-peptides.html
Discovery and optimization of selective inhibitors of protein arginine methyltransferase 5 by docking-based virtual screening -...  Discovery and optimization of selective inhibitors of protein arginine methyltransferase 5 by docking-based virtual screening -...
Protein arginine methyltransferase 5 (PRMT5) is a type II PRMT enzyme critical for diverse cellular processes and different ... Protein arginine methyltransferase 5 (PRMT5) is a type II PRMT enzyme critical for diverse cellular processes and different ... Discovery and optimization of selective inhibitors of protein arginine methyltransferase 5 by docking-based virtual screening ... Discovery and optimization of selective inhibitors of protein arginine methyltransferase 5 by docking-based virtual screening Y ...
more infohttp://pubs.rsc.org/en/content/articlelanding/2017/ob/c7ob00070g
A role for protein arginine methyltransferase 5 (PRMT5) in the mechanism of novel anticancer agent, AS1411. | Cancer Research  A role for protein arginine methyltransferase 5 (PRMT5) in the mechanism of novel anticancer agent, AS1411. | Cancer Research
Several nucleolin-interacting proteins, including protein arginine methyltransferase 5 (PRMT5), were identified by MALDI-TOF- ... A role for protein arginine methyltransferase 5 (PRMT5) in the mechanism of novel anticancer agent, AS1411.. Yun Teng and Paula ... A role for protein arginine methyltransferase 5 (PRMT5) in the mechanism of novel anticancer agent, AS1411. ... A role for protein arginine methyltransferase 5 (PRMT5) in the mechanism of novel anticancer agent, AS1411. ...
more infohttp://cancerres.aacrjournals.org/content/66/8_Supplement/1295.1
prmt2 - Protein arginine N-methyltransferase 2 - Xenopus tropicalis (Western clawed frog) - prmt2 gene & protein  prmt2 - Protein arginine N-methyltransferase 2 - Xenopus tropicalis (Western clawed frog) - prmt2 gene & protein
Arginine methyltransferase that methylates the guanidino nitrogens of arginyl residues in proteins such as histones. Involved ... protein-arginine N-methyltransferase activity Source: UniProtKB. *protein-arginine omega-N asymmetric methyltransferase ... Protein arginine N-methyltransferase 2Add BLAST. 433. Proteomic databases. PaxDb, a database of protein abundance averages ... Protein arginine N-methyltransferase 2 (EC:2.1.1.319*Search proteins in UniProtKB for this EC number. ...
more infohttps://www.uniprot.org/uniprot/B3DLB3
Myelin basic protein)-arginine N-methyltransferase - Wikipedia  Myelin basic protein)-arginine N-methyltransferase - Wikipedia
... protein methylase I, S-adenosyl-L-methionine:[myelin-basic-protein]-arginine, and omega-N-methyltransferase. Ghosh SK, Paik WK ... In enzymology, a [myelin basic protein]-arginine N-methyltransferase (EC 2.1.1.126) is an enzyme that catalyzes the chemical ... The systematic name of this enzyme class is S-adenosyl-L-methionine:[myelin-basic-protein]-arginine Nomega-methyltransferase. ... Nomega-methyl-arginine Thus, the two substrates of this enzyme are S-adenosyl methionine and myelin basic protein-arginine, ...
more infohttps://en.wikipedia.org/wiki/(Myelin_basic_protein)-arginine_N-methyltransferase
Roles of Protein Arginine Methyltransferase 7 and Jumonji Domain-Conta by Yu-Jie Hu  "Roles of Protein Arginine Methyltransferase 7 and Jumonji Domain-Conta" by Yu-Jie Hu
Among the enzymes that catalyze the methylation, protein arginine methyltransferase 7 (PRMT7) is known to modify histones to ... Jumonji domain-containing protein 6 (JMJD6) is a putative arginine demethylase that potentially antagonize PRMT7. However, the ... These biological processes can be modulated by posttranslational modifications including arginine methylation. ... and CCAAT/enhancerbinding proteins (C/EBPs). The underlying mechanisms by which JMJD6 regulate differentiation involve ...
more infohttps://escholarship.umassmed.edu/gsbs_diss/797/
Vemurafenib - Small Molecule Inhibitors of Protein Arginine Methyltransferases  Vemurafenib - Small Molecule Inhibitors of Protein Arginine Methyltransferases
Background During mammalian protein will not have ENGase activity and phrase. *Compelled expression of lineage-specific ... Background It is reported the iron-responsive element-binding protein 2 (IREB2) gene. by Ross Marshall ... 21] also found increased IREB2 protein in human being lung cells via assessment of COPD individuals with controls. Therefore ... Background It is reported the iron-responsive element-binding protein 2 (IREB2) gene rs2568494 polymorphism might be associated ...
more infohttp://welbourneprimary.com/tag/vemurafenib/
LDE225 - Small Molecule Inhibitors of Protein Arginine Methyltransferases  LDE225 - Small Molecule Inhibitors of Protein Arginine Methyltransferases
Background During mammalian protein will not have ENGase activity and phrase. *Compelled expression of lineage-specific ... The promoters, including sequences for repressor or activator proteins binding, for the and genes had been deleted and changed ... S2). Remember that prior observations indicate that 95% from the Bla SS-PspA fusion proteins is certainly partitioned between ... the anticipated size from the Bla SS-PspA fusion proteins that reacted particularly with an anti-PspA polyclonal antibody (Fig ...
more infohttp://welbourneprimary.com/tag/lde225/