IXIARO contains protamine sulfate, a compound known to cause hypersensitivity reactions in some individuals [See Description ( ... IXIARO contains protamine sulfate, a compound known to cause hypersensitivity reactions in some individuals. (5.1) (5) ... The virus suspension is treated with protamine sulfate to remove contaminating DNA and proteins. The resulting partially ... and protamine sulfate (not more than 1µg/mL). No preservatives, stabilizers, or antibiotics are added to the formulation. ...

... protamine, potassium chloride, folic acid, and acetaminophen. Preliminary studies indicate that the concomitant use of ...