Pregnane - Wikipedia
It is a parent hydrocarbon for two series of steroids stemming from 5α-pregnane (originally allopregnane) and 5β-pregnane (17β- ... Pregnanes are steroid derivatives with carbons present at positions 1 through 21. Most biologically significant pregnane ... ISBN 978-0-85404-182-4. Media related to Pregnane at Wikimedia Commons Pregnanes at the U.S. National Library of Medicine ... Pregnane, also known as 17β-ethylandrostane or as 10β,13β-dimethyl-17β-ethylgonane, is a C21 steroid and, indirectly, a parent ...
3α,17α,20β,21-tetrahydroxy-5β-Pregnane-11-one
Androstane and pregnane steroids with potent allosteric GABA receptor chloride ionophore modulating properties | RTI
Runyon, S., Rogawski, MA., Cook, E., Kepler, J., Navarro, H., Kaminski, R., & Orr, M. (2013). Androstane and pregnane steroids ... Androstane and pregnane steroids with potent allosteric GABA receptor chloride ionophore modulating properties ... Androstane and pregnane steroids with potent allosteric GABA receptor chloride ionophore modulating properties. ...
REGULATION OF DRUG METABOLISM AND INFLAMMATION BY PREGNANE X RECEPTOR
Pregnane X Receptors | Pregnane X Receptors pathway | Pregnane X Receptors inhibitors
Check Pregnane X Receptors pathway , inhibitors reviews and assay information. ... Pregnane X Receptors Inhibitors on signaling pathway are available at Adooq Bioscience. ... Meclizine is a human pregnane X receptor (hPXR) agonist. It possesses anticholinergic, central nervous system depressant, and ...
Plus it
pregnane X receptor. Oatp2. organic anion transporting polypeptide. PCN. pregnenolone-16α-carbonitrile. PXR-KO. PXR-knockout ... Coordinate Regulation of Xenobiotic and Bile Acid Homeostasis by Pregnane X Receptor. Jeff Staudinger, Yaping Liu, Ajay Madan, ... Coordinate Regulation of Xenobiotic and Bile Acid Homeostasis by Pregnane X Receptor. Jeff Staudinger, Yaping Liu, Ajay Madan, ... Coordinate Regulation of Xenobiotic and Bile Acid Homeostasis by Pregnane X Receptor. Jeff Staudinger, Yaping Liu, Ajay Madan, ...
Plus it
Treatment of rats with pregnenolone-16α-carbonitrile (PCN), a ligand for the rodent pregnane X receptor (PXR), significantly ... Induction of Rat Organic Anion Transporting Polypeptide 2 by Pregnenolone-16α-carbonitrile Is via Interaction with Pregnane X ... Induction of Rat Organic Anion Transporting Polypeptide 2 by Pregnenolone-16α-carbonitrile Is via Interaction with Pregnane X ... Induction of Rat Organic Anion Transporting Polypeptide 2 by Pregnenolone-16α-carbonitrile Is via Interaction with Pregnane X ...
Pregnanes | Profiles RNS
"Pregnanes" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical Subject ... This graph shows the total number of publications written about "Pregnanes" by people in this website by year, and whether " ... Saturated derivatives of the steroid pregnane. The 5-beta series includes PROGESTERONE and related hormones; the 5-alpha series ... Below are the most recent publications written about "Pregnanes" by people in Profiles. ...
Pregnane X-receptor promotes stem cell-mediated colon cancer relapse.
EPP Ltd - 5α-Pregnane-3,11,20-trione
Melanogenesis inhibitory pregnane glycosides from Cynanchum atratum - Fingerprint - Korea University
In Vivo Responses of the Human and Murine Pregnane X Receptor to Dexamethasone in Mice<...
Scheer, N., Ross, J., Kapelyukh, Y., Rode, A., & Wolf, C. R. (2010). In Vivo Responses of the Human and Murine Pregnane X ... Scheer, N, Ross, J, Kapelyukh, Y, Rode, A & Wolf, CR 2010, In Vivo Responses of the Human and Murine Pregnane X Receptor to ... In Vivo Responses of the Human and Murine Pregnane X Receptor to Dexamethasone in Mice. In: Drug Metabolism and Disposition. ... In Vivo Responses of the Human and Murine Pregnane X Receptor to Dexamethasone in Mice. Drug Metabolism and Disposition. 2010 ...
Protein arginine methyltransferase 1 may be involved in pregnane x receptor-activated overexpression of multidrug resistance 1...
Purpose: Pregnane x receptor (PXR) - activated overexpression of the multidrug resistance 1 (MDR1) gene is an important way for ... Protein arginine methyltransferase 1 may be involved in pregnane x receptor-activated overexpression of multidrug resistance 1 ... Keywords: multidrug resistance, p-glycoprotein, protein arginine methyl transferase 1, pregnane X receptor ...
EP 0980384 A1 20000223 - PREGNANE 3,2O DIOL MONO- AND DI-SULPHATES
"The Interface between Cell Signaling Pathways and Pregnane X Receptor" by Robert S. Rogers, Annemarie Parker et al.
... pregnane X receptor (PXR, NR1I2) is a well-characterized nuclear receptor (NR) that regulates the expression of genes in the ... Highly expressed in the enterohepatic system, pregnane X receptor (PXR, NR1I2) is a well-characterized nuclear receptor (NR) ... PARylation, SUMOylation, acetylation, cell signaling, nuclear receptor, phosphorylation, pregnane X receptor, ubiquitination, ... The Interface between Cell Signaling Pathways and Pregnane X Receptor. Cells. 2021; 10(11). doi: 10.3390/cells10113262. ...
17-BETA-HYDROXY-5-ALPHA,17-ALPHA-PREGNANE-3-BETA,20-BETA,21-TRIYL TRIACETATE AldrichCPR | Sigma-Aldrich
Fecal 20-oxo-pregnane concentrations in free-ranging African elephants (Loxodonta africana) treated with porcine zona pellucida...
Quantitative High-Throughput Profiling of Environmental Chemicals and Drugs that Modulate Farnesoid X Receptor | Scientific...
When compared with other functionally related receptors such as the pregnane X receptor (PXR), the majority of the FXR-active ... Identification of clinically used drugs that activate pregnane X receptors. Drug Metab Dispos 39, 151-159, 10.1124/dmd. ... Activation of the steroid and xenobiotic receptor (human pregnane X receptor) by nontaxane microtubule-stabilizing agents. Clin ...
Frontiers | Immunological Feature and Transcriptional Signaling of Ly6C Monocyte Subsets From Transcriptome Analysis in Control...
Pregnenediones | Harvard Catalyst Profiles | Harvard Catalyst
Results for 'Nuclear Receptors' | Abcam: antibodies, proteins, kits...
Table of Contents - February 17, 2016, 36 (7) | Journal of Neuroscience
Isoform-Specific Regulation of Cytochromes P450 Expression by Estradiol and Progesterone | Drug Metabolism & Disposition
2003) Expression and potential roles of pregnane X receptor in endometrial cancer. J Clin Endocrinol Metab 88:4446-4454. ... In contrast, progesterone has been shown to enhance activities of pregnane X receptor (PXR)-driven promoters in various ... 2005) Human CYP2C8 is transcriptionally regulated by the nuclear receptors constitutive androstane receptor, pregnane X ... in the human liver and intestine is mediated by the xenobiotic sensors pregnane X receptor (PXR) and constitutively activated ...
Organochlorine Contaminant, Triclosan Leads to Increased Levels of Trihalomethanes in Drinking Water Sources across the United...
Carbohydrates and Starches
Receptor structure predicts drug interactions | The Scientist Magazine®
The human nuclear pregnane X receptor has a hydrophobic ligand-binding cavity with a small number of polar residues that are ... The human nuclear pregnane X receptor has a hydrophobic ligand-binding cavity with a small number of polar residues that are ... In the human liver, nuclear pregnane X receptor (hPXR) activates cytochrome P450-3A in response to a wide variety of drugs and ...