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*  IJMS | Free Full-Text | New Insights into Functional Roles of the Polypyrimidine Tract-Binding Protein | HTML
... is an intensely studied RNA binding protein involved in several post-transcriptional regulatory events of gene expression. ... Detailed studies of the structural properties of PTB have contributed to our understanding of the mechanism of RNA binding by ... Initially described as a pre-mRNA splicing regulator, PTB is now widely accepted as a multifunctional protein shuttling between ... Accordingly, PTB can interact with selected RNA targets, structural elements and proteins. There is increasing evidence that ...
http://www.mdpi.com/1422-0067/14/11/22906/htm
*  Activation of α-Tropomyosin Exon 2 Is Regulated by the SR Protein 9G8 and Heterogeneous Nuclear Ribonucleoproteins H and F
Protein kinase A phosphorylation modulates transport of the polypyrimidine tract-binding protein. Proc. Natl. Acad. Sci. USA ... Polypyrimidine tract binding protein antagonizes exon definition. Mol. Cell. Biol. 21:3281-3288. [PMC free article] [PubMed] ... Polypyrimidine tract-binding protein is involved in vivo in repression of a composite internal/3′-terminal exon of the Xenopus ... Autoregulation of polypyrimidine tract binding protein by alternative splicing leading to nonsense-mediated decay. Mol. Cell 13 ...
http://pubmedcentralcanada.ca/pmcc/articles/PMC1636816/?lang=en-ca
*  Frontiers | Post-Transcriptional Control of the Hypoxic Response by RNA-Binding Proteins and MicroRNAs | Frontiers in Molecular...
RBPs such as HuR (human antigen R), PTB (polypyrimidine tract-binding protein), heterogeneous nuclear ribonucleoproteins ( ... RBPs such as HuR (human antigen R), PTB (polypyrimidine tract-binding protein), heterogeneous nuclear ribonucleoproteins ( ... iron-response element binding proteins (IRPs), and cytoplasmic polyadenylation-element-binding proteins (CPEBs), selectively ... iron-response element binding proteins (IRPs), and cytoplasmic polyadenylation-element-binding proteins (CPEBs), selectively ...
https://www.frontiersin.org/articles/10.3389/fnmol.2011.00007/full
*  A novel isoform ratio switch of the polypyrimidine tract binding protein | Scholars@Duke
A novel isoform ratio switch of the polypyrimidine tract binding protein's profile, publications, research topics, and co- ... A novel isoform ratio switch of the polypyrimidine tract binding protein Book Section ... we present evidence for a novel switch in the ratio of the two major iso-forms of the polypyrimidine tract binding protein (PTB ... The two most prevalent isoforms of PTB were found to bind to an RNA probe containing a pyrimidine stretch. Western blot ...
https://scholars.duke.edu/display/pub1132996
*  HNRPF - Wikipedia
2000). "Cooperative assembly of an hnRNP complex induced by a tissue-specific homolog of polypyrimidine tract binding protein ... The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi- ... The hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre ... Matunis MJ, Xing J, Dreyfuss G (1994). "The hnRNP F protein: unique primary structure, nucleic acid-binding properties, and ...
https://en.wikipedia.org/wiki/HNRPF
*  ptbp1b, polypyrimidine tract binding protein 1b - Creative Biogene
PTBP1B; polypyrimidine tract binding protein 1b; cb363; sb:cb363; id:ibd2901; im:7145323; wu:fa04b05; wu:fb16f08; wu:fc58e03; ... Creative Biogene Introduces Innovative Expression Vectors for High Level of Protein Production ...
https://www.creative-biogene.com/symbolsearch_ptbp1b.html
*  Polypyrimidine tract-binding protein - Wikipedia
Polypyrimidine tract-binding protein, also known as PTB or hnRNP I, is an RNA-binding protein. PTB functions mainly as a ... polypyrimidine tract-binding protein at the US National Library of Medicine Medical Subject Headings (MeSH). ... Polypyrimidine tract Valcárcel J, Gebauer F (November 1997). "Post-transcriptional regulation: the dawn of PTB". Curr. Biol. 7 ...
https://en.wikipedia.org/wiki/Polypyrimidine_tract-binding_protein
*  Polypyrimidine tract-binding protein 2
This protein is very similar to the polypyrimidine tract binding protein (PTB) but most of its isoforms are expressed primarily ... RNA-binding protein which binds to intronic polypyrimidine tracts and mediates negative regulation of exons splicing. May ... The protein encoded by this gene binds to intronic polypyrimidine clusters in pre-mRNA molecules and is implicated in ... controlling the assembly of other splicing-regulatory proteins. ... HCA RNA Cell Line for Polypyrimidine tract-binding protein 2. A ...
https://pharos.nih.gov/idg/targets/PTBP2
*  Inserm - Expression analysis of the polypyrimidine tract binding protein (PTBP1) and its paralogs PTBP2 and PTBP3 during...
... family of RNA-binding proteins plays a critical role in development through the regulation of post-transcriptional events. We ... Abstract : The PTB (polypyrimidine tract binding protein) family of RNA-binding proteins plays a critical role in development ... Expression analysis of the polypyrimidine tract binding protein (PTBP1) and its paralogs PTBP2 and PTBP3 during Xenopus ... Expression analysis of the polypyrimidine tract binding protein (PTBP1) and its paralogs PTBP2 and PTBP3 during Xenopus ...
https://www.hal.inserm.fr/inserm-00870920
*  Buy PTBP1-polypyrimidine tract binding protein 1 Gene (PTXBC004383)
Buy online PTBP1-polypyrimidine tract binding protein 1 Gene from ProteoGenix cat# PTXBC004383. Shop among our wide range of ... polypyrimidine tract-binding protein 1; 57 kDa RNA-binding protein PPTB-1; RNA-binding protein; heterogeneous nuclear ... polypyrimidine tract binding protein (heterogeneous nuclear ribonucleoprotein I); polypyrimidine tract binding protein 1. ... polypyrimidine tract binding protein 1. Synonyms: HNRNP-I; HNRNPI; HNRPI; PTB; PTB-1; PTB-T; PTB2; PTB3; PTB4; pPTB; ...
https://www.proteogenix-products.com/7058-ptbp1-polypyrimidine-tract-binding-protein-1-gene.html
*  "A single polypyrimidine tract binding protein (PTB) binding site media" by Haihong Shen, Julie L. C. Kan et al.
Here we show that the inhibitor contains two binding sites for polypyrimidine tract binding protein (PTB). Mutational analysis ... Collectively, our results indicate that a single PTB binding site can function as an inhibitor that regulates alternative ... A single polypyrimidine tract binding protein (PTB) binding site mediates splicing inhibition at mouse IgM exons M1 and M2 ... Here we show that the inhibitor contains two binding sites for polypyrimidine tract binding protein (PTB). Mutational analysis ...
https://escholarship.umassmed.edu/oapubs/1621/
*  The rat poly Pyrimidine Tract binding protein (PTB) interacts with a single-stranded DNA motif in a liverspecific enhancer
Microsequencing revealed that this protein is the rat homologue of the mouse and human poly Pyrimidine Tract binding protein ( ... The rat poly Pyrimidine Tract binding protein (PTB) interacts with a single-stranded DNA motif in a liverspecific enhancer. In ... We characterized and purified a protein from rat liver which specifically binds to a DNA motif present in a liver-specific ... Binding is highly sequence-specific and coincides with a region known to be essential for function of the enhancer. ...
https://epub.ub.uni-muenchen.de/3214/index.html
*  New Arabidopsis DNA 08-Aug-1998
Arabidopsis thaliana polypyrimidine tract-binding protein homolog (PTB) mRNA, complete cds. PTB; polypyrimidine tract-binding ... like protein; F7J7.40; UV-damaged DNA-binding protein- like; F7J7.50; G10 - like protein; F7J7.60; amino acid transport protein ... putative DNA-binding protein; F4I18.18; F4I18.19; F4I18.20; DNA-binding protein, dbp; F4I18.21; putative ATP-dependent RNA ... Arabidopsis thaliana H-protein promoter binding factor-2a mRNA, complete cds. H-protein promoter binding factor-2a. AF079504 ...
http://www.bio.net/bionet/mm/arab-gen/1998-August/006547.html
*  Human PTBP1 peptide (ab23105) | Abcam
Polypyrimidine tract binding protein (heterogeneous nuclear ribonucleoprotein I). *Polypyrimidine Tract Binding Protein 1 ... Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the ... Proteins and Peptides. Proteomics tools. Agonists, activators, antagonists and inhibitors. Lysates. Multiplex miRNA assays. By ... May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons ...
https://www.abcam.com/human-ptbp1-peptide-ab23105.html
*  Spectroscopy - Science - Diamond Light Source
Crystallographic analysis of the interaction of splicing co-regulators polypyrimidine tract binding protein (PTB) and Raver1 ... Putting proteins under pressure Dec 3, 2014 Investigating protein-protein interactions at high ... read on Putting proteins ... read on Crystallographic analysis of the interaction of splicing co-regulators polypyrimidine tract binding protein (PTB) and ... Protein punch a blow for bacteria Mar 7, 2016 The incredible structure of a human pore that punches ... read on Protein punch a ...
http://www.diamond.ac.uk/Science/Research/Highlights/2016/Spectroscopy/
*  2010 - Science - Diamond Light Source
Crystallographic analysis of the interaction of splicing co-regulators polypyrimidine tract binding protein (PTB) and Raver1 ... Complex between Neisseria meningitidis factor H binding protein and two domains from human complement factor H Oct 12, 2010 The ...
https://www.diamond.ac.uk/Science/Research/Highlights/2010/
*  ptbp2b - PCR Primer Pair - Probe | PrimePCR | Bio-Rad
Polypyrimidine tract binding protein 2b. Aliases:. Not Available. RefSeq:. XM_005163345 NM_001100007 XR_223177. ...
http://www.bio-rad.com/en-us/prime-pcr-assays/assay/qdrecip0039156-primepcr-probe-assay-ptbp2b-zebrafish
*  ptbp1b - PCR Primer Pair - Probe | PrimePCR | Bio-Rad
Polypyrimidine tract binding protein 1b. Aliases:. Not Available. RefSeq:. XM_005155941 XM_005155939 XM_005155938 NM_001122654 ...
http://www.bio-rad.com/en-us/prime-pcr-assays/assay/qdrecip0039580-primepcr-probe-assay-ptbp1b-zebrafish
*  MicroRNA-124 Controls the Proliferative, Migratory, and Inflammatory Phenotype of Pulmonary Vascular FibroblastsNovelty and...
MicroRNA-124(miR-124) regulates polypyrimidine tract-binding protein 1 (PTBP1) mRNA and protein expression via direct binding ... Polypyrimidine tract-binding protein 1 (PTBP1) mRNA and protein expression is increased in adventitial fibroblasts isolated ... Polypyrimidine tract binding protein and Notch1 are independently re-expressed in glioma. Mod Pathol. 2006;19:1034-1041. ... Polypyrimidine tract-binding protein (PTB) differentially affects malignancy in a cell line-dependent manner. J Biol Chem. 2008 ...
http://circres.ahajournals.org/content/114/1/67
*  hnRNP I (mouse)
Home > Protein > hnRNP I mouse. human. rat. New Protein Search:. Polypyrimidine tract-binding protein 1 ... Protein Mutation Frequency in Cancer. The 'lollipop plot' above illustrates recurrent (observed in 3 or more out of 4440 TCGA ...
https://www.phosphosite.org/proteinAction.action?id=3990&showAllSites=true
*  ptbp2a - PCR Primer Pair - SYBR | PrimePCR | Bio-Rad
Polypyrimidine tract binding protein 2a. Aliases:. Not Available. RefSeq:. NM_001013562. Ensembl:. ENSDARG00000015230 ...
http://www.bio-rad.com/en-us/prime-pcr-assays/assay/qdrecid0019062-primepcr-sybr-green-assay-ptbp2a-zebrafish
*  Integrative analysis reveals functional and regulatory roles of H3K79me2 in mediating alternative splicing | SpringerLink
... is a co-transcriptional splicing process not only controlled by RNA-binding splicing factors, but also mediated by epigenetic ... Significance of polypyrimidine tract-binding protein 1 expression in colorectal cancer. Mol Cancer Ther. 2015;14(7):1705-16. ... Involvement of polypyrimidine tract-binding protein (PTBP1) in maintaining breast cancer cell growth and malignant properties. ... Paz I, Kosti I, Ares M, Cline M, Mandel-Gutfreund Y. RBPmap: a web server for mapping binding sites of RNA-binding proteins. ...
https://link.springer.com/article/10.1186/s13073-018-0538-1
*  Reed, R.<...
Polypyrimidine Tract-Binding Protein Medicine & Life Sciences planning data Social Sciences Blogging Medicine & Life Sciences ...
https://pennstate.pure.elsevier.com/en/persons/robyn-reed
*  ADHDgene Database
polypyrimidine tract binding protein 2. Location. 1p21.3. Position. chr1:97187221-97289294, 1. ... mRNA binding. molecular function. IEA 11. GO:2000177. regulation of neural precursor cell proliferation. biological process. ...
http://adhd.psych.ac.cn/geneDetail.do?name=PTBP2