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*  OriGene - PABPC1 (NM 002568) shRNA
Summary: This gene encodes a poly(A) binding protein. The protein shuttles between the nucleus and cytoplasm and binds to the 3 ... The binding of this protein to poly(A) promotes ribosome recruitment and translation initiation; it is also required for poly(A ... The gene is part of a small gene family including three protein-coding genes and several pseudogenes.[provided by RefSeq, Aug ... HuSH 29-mer shRNA against Luciferase Protein (in pRS Vector), 5 ug ...
http://www.origene.com/shRNA/TR310637.aspx
*  Insulin-like growth factor binding protein 7 for treatment of cancer - University of Massachusetts
Conjugates of insulin-like growth factor binding protein-4 and poly (ethylene glycol). 2006-05-11. Lang et al.. ... Wilson et al., "Interaction of IGF-Binding Protein-Related Protein 1 with a Novel Protein, Neuroendocrine Differentiation ... "Insulin-like growth factor binding protein-related protein 1 (IGFBP-rP1) is a potential tumor suppressor protein for prostate ... and insulin growth factor binding protein 7 (IGFBP7), which encodes a secreted protein with weak homology to IGF binding ...
http://www.freepatentsonline.com/9248163.html
*  Acervo Digital: An interaction between two RNA binding proteins, Nab2 and Pub1, links mRNA Processing/Export and mRNA stability
Poly(U) binding protein 1 (Pub1) is a cytoplasmic Saccharomyces cerevisiae mRNA binding protein that stabilizes transcripts ... as being a Pub1-interacting protein. Nab2 is an essential nucleocytoplasmic shuttling mRNA binding protein that regulates poly( ... An interaction between two RNA binding proteins, Nab2 and Pub1, links mRNA Processing/Export and mRNA stability. Author(s): * ... mRNA stability is modulated by elements in the mRNA transcript and their cognate RNA binding proteins. ...
https://acervodigital.unesp.br/handle/11449/7603
*  Cell-specific localization of insulin-like growth factor binding protein mRNAs in rat liver | Gastrointestinal and Liver...
2 μg poly(A)+-enriched RNA from adult rat liver; hepatocytes, 2 μg poly(A)+-enriched RNA from elutriated cells; Kupffer cell, ... 1994) Expression of insulin-like growth factor binding protein-4 and -5 mRNAs in adult rat forebrain. J. Comp. Neurol. 339:91- ... GH receptor mRNA (4.3 kb) and a smaller mRNA of 1.3 kb encoding GH binding protein were detected at high levels in liver (data ... Detection of IGF binding protein (IGFBP) mRNAs in rat liver and isolated hepatic cells by Northern blot hybridization. Growth ...
http://ajpgi.physiology.org/content/278/3/G447.long
*  Tankyrase 2: Tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
... ate the telomere-binding proteins TRF-1 and TRF-2, thus blocking their DNA-binding activity and controlling telomere extension ... Tankyrase 1 and tankyrase 2 are poly(ADP-ribosyl)ases that are distinguishable from other members of the enzyme family by the ... find other proteinsAll proteins. GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last ... Crystal structures of tankyrase 2 with the compounds showed that they bind to the nicotinamide binding site of the catalytic ...
http://www.gopubmed.org/tankyrase+2.html
*  RCSB PDB - Gene View - PABPC1 - poly(A) binding protein cytoplasmic 1
The PDB archive contains information about experimentally-determined structures of proteins, nucleic acids, and complex ... White boxes represent UTRs (untranslated regions). Orange: protein coding regions. The black lines connecting boxes represent ...
https://www.rcsb.org/pdb/gene/PABPC1
*  Poly(A)-binding protein - Wikipedia
Poly(A)-binding protein (PAB or PABP) is a RNA-binding protein which binds to the poly(A) tail of mRNA. The poly(A) tail is ... Rotavirus RNA-binding protein NSP3 interacts with eIF4GI and evicts the poly(A) binding protein from eIF4F. NSP3A by taking the ... This binding forms the characteristic loop structure of eukaryotic protein synthesis. Poly(A)-binding proteins in the cytosol ... poly(G), and poly(C) were reportedly lower or undetectable in comparison. This shows that the poly(A)-binding protein is ...
https://en.wikipedia.org/wiki/Poly(A)-binding_protein
*  Pabpc4 poly(A) binding protein, cytoplasmic 4 [Mus musculus (house mouse)] - Gene - NCBI
Pabpc4 poly(A) binding protein, cytoplasmic 4 [Mus musculus] Pabpc4 poly(A) binding protein, cytoplasmic 4 [Mus musculus]. Gene ... PABP; Poly-adenylate binding protein, unique domain. * XM_006503022.2 → XP_006503085.1 polyadenylate-binding protein 4 isoform ... PABP; Poly-adenylate binding protein, unique domain. * XM_017320151.1 → XP_017175640.1 polyadenylate-binding protein 4 isoform ... PABP; Poly-adenylate binding protein, unique domain. * XM_006503023.2 → XP_006503086.1 polyadenylate-binding protein 4 isoform ...
https://www.ncbi.nlm.nih.gov/gene/?term=230721
*  Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1) Antikörper
... binding protein 1-A , poly(A)-binding protein 1-A , polyadenylate-binding protein 1-A , xPABP1-A , poly(A) binding protein, ... Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1) Antigen-Profil Protein Überblick This gene encodes a poly(A) binding protein. ... polyadenylate-binding protein 1-like , poly(A) binding protein, cytoplasmic 1 , polyadenylate-binding protein 1 , PABP 1-A , ... Weitere Produktkategorien zu Poly(A) Binding Protein, Cytoplasmic 1 Antikörper * 75 anti-Poly(A) Binding Protein, Cytoplasmic 1 ...
http://www.antikoerper-online.de/abstract/Poly
*  WikiGenes - PABPC1L2B - poly(A) binding protein, cytoplasmic 1...
wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary ... knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound ...
https://www.wikigenes.org/e/gene/e/645974.html
*  PCBP2 - Poly(rC)-binding protein 2 - Homo sapiens (Human) - PCBP2 gene & protein
Poly(rC)-binding protein 2Imported. ,p>Information which has been imported from another database using automatic procedures.,/p ... tr,F8VXH9,F8VXH9_HUMAN Poly(rC)-binding protein 2 (Fragment) OS=Homo sapiens OX=9606 GN=PCBP2 PE=1 SV=1 ... Poly(rC)-binding protein 2 (Alpha-CP2) (Heterogeneous nuclear ribonucleoprotein E2, hnRNP E2) ... to allow unambiguous identification of a protein.,p>,a href='/help/protein_names' target='_top'>More...,/a>,/p>Protein namesi. ...
https://www.uniprot.org/uniprot/F8VXH9
*  PABPC1L2A (poly(A) binding protein cytoplasmic 1 like 2A)
... binding protein cytoplasmic 1 like 2A), Authors: Dessen P. Published in: Atlas Genet Cytogenet Oncol Haematol. ... RNA binding extracellular exosome Ontology : EGO-EBI. RNA binding extracellular exosome NDEx Network. PABPC1L2A. ... Protein : pattern, domain, 3D structure. UniProt/SwissProt. Q5JQF8 [function] [subcellular_location] [family_and_domains] [ ... Human Protein Atlas. ENSG00000186288-PABPC1L2A [pathology] [cell] [tissue]. ...
http://atlasgeneticsoncology.org/Genes/GC_PABPC1L2A.html
*  JCI - The poly(A)-binding protein partner Paip2a controls translation during late spermiogenesis in mice
Kuhn U, Pieler T. Xenopus poly(A) binding protein: functional domains in RNA binding and protein-protein interaction. J Mol ... General RNA-binding proteins have a function in poly(A)-binding protein-dependent translation. EMBO J. 2009;28(1):58-68.. View ... Poly(A)-binding protein-interacting protein 1 binds to eukaryotic translation initiation factor 3 to stimulate translation. Mol ... The multiple RNA-binding domains of the mRNA poly(A)-binding protein have different RNA-binding activities. Mol Cell Biol. 1991 ...
https://www.jci.org/articles/view/43350
*  Insights from a Paradigm Shift: How the Poly(A)-Binding Protein Brings Translating mRNAs Full Circle
U. Kühn and T. Pieler, "XenopusPoly(A) binding protein: functional domains in RNA binding and protein-protein interaction," ... H. Le, K. S. Browning, and D. R. Gallie, "The phosphorylation state of poly(A)-binding protein specifies its binding to poly(A ... Y. V. Svitkin, V. M. Evdokimova, A. Brasey et al., "General RNA-binding proteins have a function in poly(A)-binding protein- ... "Rotavirus RNA-binding protein NSP3 interacts with eIF4GI and evicts the poly(A) binding protein from eIF4F," EMBO Journal, vol ...
https://www.hindawi.com/journals/njos/2014/873084/ref/
*  Control of translation and miRNA-dependent repression by a novel poly(A) binding protein, hnRNP-Q. - PubMed - NCBI
... binds poly(A) by default when PABP binding is inhibited. In addition, hnRNP-Q2 competes with PABP for binding to poly(A) in ... The poly(A) binding protein (PABP) simultaneously interacts with the 3' poly(A) tail of the mRNA and the eukaryotic translation ... Control of translation and miRNA-dependent repression by a novel poly(A) binding protein, hnRNP-Q.. Svitkin YV1, Yanagiya A, ... poly(A), poly(G), poly(U), and poly(C), were included in the reaction mixtures at 5 µg/ml concentrations. (B) Recombinant hnRNP ...
https://www.ncbi.nlm.nih.gov/pubmed/23700384
*  Cytoplasmic poly (A) binding protein (PABPC2) critically regulates epidermal maintenance and turnover in planarian Schmidtea...
Cytoplasmic poly (A) binding protein (PABPC2) critically regulates epidermal maintenance and turnover in planarian Schmidtea ... Cytoplasmic poly (A) binding protein (PABPC2) critically regulates epidermal maintenance and turnover in planarian Schmidtea ... Cytoplasmic poly (A) binding protein (PABPC2) critically regulates epidermal maintenance and turnover in planarian Schmidtea ... Cytoplasmic poly (A) binding protein (PABPC2) critically regulates epidermal maintenance and turnover in planarian Schmidtea ...
http://dev.biologists.org/content/early/2017/08/16/dev.152942
*  Poly (C) Binding Protein family is a transcription factor in mu-opioid receptor gene expression | Molecular Pharmacology
Poly (C) Binding Protein family is a transcription factor in mu-opioid receptor gene expression. Sung-Su Kim, Krishan K. Pandey ... Poly (C) Binding Protein family is a transcription factor in mu-opioid receptor gene expression. Sung-Su Kim, Krishan K. Pandey ... Poly (C) Binding Protein family is a transcription factor in mu-opioid receptor gene expression. Sung-Su Kim, Krishan K. Pandey ... Poly (C) Binding Protein family is a transcription factor in mu-opioid receptor gene expression ...
http://molpharm.aspetjournals.org/content/early/2005/06/02/mol.105.012245
*  The rat poly Pyrimidine Tract binding protein (PTB) interacts with a single-stranded DNA motif in a liverspecific enhancer
Microsequencing revealed that this protein is the rat homologue of the mouse and human poly Pyrimidine Tract binding protein ( ... The rat poly Pyrimidine Tract binding protein (PTB) interacts with a single-stranded DNA motif in a liverspecific enhancer. In ... We characterized and purified a protein from rat liver which specifically binds to a DNA motif present in a liver-specific ... Binding is highly sequence-specific and coincides with a region known to be essential for function of the enhancer. ...
https://epub.ub.uni-muenchen.de/3214/index.html
*  A conserved role for cytoplasmic poly(A)‐binding protein 1 (PABPC1) in nonsense‐mediated mRNA decay | The EMBO Journal
Hosoda N, Lejeune F, Maquat LE (2006) Evidence that poly(A) binding protein C1 binds nuclear pre‐mRNA poly(A) tails. Mol Cell ... Bernstein P, Ross J (1989) Poly(A), poly(A) binding protein and the regulation of mRNA stability. Trends Biochem Sci 14: 373- ... Moreover, tethering the poly(A)‐binding protein (Pab1p) downstream of a PTC, which is likely to mimic a normal 3′ UTR, leads to ... A conserved role for cytoplasmic poly(A)‐binding protein 1 (PABPC1) in nonsense‐mediated mRNA decay. Isabelle Behm‐Ansmant, ...
http://emboj.embopress.org/content/26/6/1591
*  PLOS Pathogens: A Viral Nuclear Noncoding RNA Binds Re-localized Poly(A) Binding Protein and Is Required for Late KSHV Gene...
RNA is to bind poly(A) binding protein, which normally binds poly(A) tails of mRNAs in the cytoplasm but is re-localized into ... The interaction between PAN RNA and re-localized poly(A) binding protein is important for formation of new virus, in particular ... This poly(A) tail has been implicated as important for regulating mRNA translation, stability and export. During the lytic ... for the synthesis of proteins made late in infection. Our study provides new insight into the function of this noncoding RNA ...
http://journals.plos.org/plospathogens/article/comments?id=10.1371/journal.ppat.1002300
*  Evolutionary history exposes radical diversification among classes of interaction partners of the MLLE domain of plant poly(A)...
... binding proteins (PABPs) are evolutionarily conserved proteins that have important functions in the regulation of translation ... This class often consists of four to six highly conserved RNA-binding proteins, which suggests that major redundancy is present ... Most PABPs encode a C-terminal domain known as the MLLE domain (previously PABC or CTC), which can mediate protein interactions ... In earlier work we identified and predicted that four classes of MLLE-interacting proteins were present in Arabidopsis thaliana ...
https://bmcevolbiol.biomedcentral.com/articles/10.1186/s12862-015-0475-1
*  Presence of a Poly(A) Binding Protein and Two Proteins with Cell Cycle-Dependent Phosphorylation in Crithidia fasciculata mRNA...
The RBP63 protein is a member of the poly(A) binding protein family. Homologs of RBP45 and RBP33 proteins were found only among ... Identification of a C-terminal poly(A)-binding protein (PABP)-PABP interaction domain: role in cooperative binding to poly(A) ... RBP63 is a poly(A) binding protein that binds to the cycling sequence.Sequence analysis of RBP63 predicts it to be a member of ... Poly(A) binding protein is contained in the CSBP II protein complex. (A) Rabbit antibody developed against T. brucei PABP ...
https://ec.asm.org/content/3/5/1185?ijkey=6e425439bd14c6c2d1ee1ac5511bf73f0e38a535&keytype2=tf_ipsecsha
*  Differential utilization of poly(rC) binding protein 2 in translation directed by picornavirus IRES elements. - Semantic Scholar
... poly(rC) binding protein 2 (PCBP2). Upon depletion of PCBP2, these extracts possessed a significantly diminished capacity to ... Although a number of cellular proteins have been shown to be involved in picornavirus RNA translation, the precise role of ... translation reactions were conducted in HeLa cell cytoplasmic translation extracts that were depleted of the cellular protein, ... Poly(rC) binding protein 2 acts as a negative regulator of IRES-mediated translation of Hr mRNA. *Jeong-Ki Kim, Injung Kim, +5 ...
https://www.semanticscholar.org/paper/Differential-utilization-of-poly%28rC%29-binding-2-in-Walter-Nguyen/7fd73b17c2d81c4c89484d21d7025d2f50fc8e42
*  Lirias: Makorin Ring Zinc Finger Protein 1 (MKRN1), a Novel Poly(A)-binding Protein-interacting Protein, Stimulates Translation...
Makorin Ring Zinc Finger Protein 1 (MKRN1), a Novel Poly(A)-binding Protein-interacting Protein, Stimulates Translation in ... In this study we identify RING zinc finger protein Makorin 1 (MKRN1), a bona fide RNA-binding protein, as a binding partner of ... The poly(A)-binding protein (PABP), a key component of different ribonucleoprotein complexes, plays a crucial role in the ... Makorin Ring Zinc Finger Protein 1, 2011.pdf. main article. Published 3538Kb. Adobe PDF. View/Open. Request a copy ...
https://lirias.kuleuven.be/handle/123456789/334352
*  Poly(rC)-binding protein 1
... binding protein. It contains three K-homologous (KH) domains which may be involved in RNA binding. This encoded protein ... Expression of poly(C)-binding protein 1 (PCBP1) in NSCLC as a negative regulator of EMT and its clinical value.. ... Downregulated Poly-C binding protein-1 is a novel predictor associated with poor prognosis in Acute Myeloid Leukemia.. ... Poly r(C) binding protein-1 is central to maintenance of cancer stem cells in prostate cancer cells.. ...
https://pharos.nih.gov/idg/targets/PCBP1