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*  Nanotargeting Atherosclerotic Plaques | Medgadget
... in atherosclerotic plaques. Fumagillin is an antiangiogenesis drug. ... in atherosclerotic plaques. Fumagillin is an antiangiogenesis drug.. "Previously we reported that we can visualize plaques ... If a plaque ruptures, it can block blood flow to the heart or brain, causing heart attack or stroke.. While growing, plaques ... The diet caused numerous small plaques in the rabbits' aortas, but the plaques were considered to be at an early stage of ...
https://www.medgadget.com/2006/08/nanotargeting_a.html
*  Vascular endothelial growth factor enhances atherosclerotic plaque progression. - PubMed - NCBI
Vascular endothelial growth factor enhances atherosclerotic plaque progression.. Celletti FL1, Waugh JM, Amabile PG, Brendolan ... can promote angiogenesis but may also exert certain effects to alter the rate of atherosclerotic plaque development. To ... Plaque macrophage and endothelial cell content also increased disproportionately over controls. In order to confirm that the ... VEGF significantly increased macrophage levels in bone marrow and peripheral blood and increased plaque area 5-, 14- and 4-fold ...
https://www.ncbi.nlm.nih.gov/pubmed/11283668?dopt=Abstract
*  Imaging Modalities to Identity Inflammation in an Atherosclerotic Plaque
... leading to plaque rupture [4]. Detection of atherosclerotic plaques at this inflammatory stage with the use of invasive and ... distribution of the plaque, and severity of the plaque in addition to its ability to detect the plaque cross-sectional area, ... 10−5 cm2·s−1 in plaque lipid core, cm2·s−1 in a collagenous cap, and × 10−5 cm2·s−1 in normal media [84]. Water will diffuse ... Imaging Modalities to Identity Inflammation in an Atherosclerotic Plaque. Sunny Goel,1 Avraham Miller,1 Chirag Agarwal,1 Elina ...
https://www.hindawi.com/journals/rrp/2015/410967/
*  Atherosclerotic Plaque as Infected Biofilm | GreenMedInfo | Blog Entry
Formation of atherosclerotic plaque tends to occur at sites of injury, such as at bifurcations where shear forces are maximal, ... Atherosclerotic Plaque as Infected Biofilm. The main failing in most of Western Medicine is misdiagnosis. You cannot ... Stephen Fry runs his own microbiology lab where he examines high powered views of biofilms in atherosclerotic plaque material ... So, the idea of atherosclerotic plaque as infected biofilm certainly fits the pattern of commonly affected sites in the ...
http://www.greenmedinfo.com/blog/atherosclerotic-plaque-infected-biofilm
*  Biomechanical structural stresses of atherosclerotic plaques.
Degree of stenosis, which is the current criterion for assessment of atherosclerotic disease severity, has been observed to h ... Atherosclerotic plaques may rupture without warning, causing fatal clinical events such as myocardial infarction and stroke. ... Atherosclerotic plaques may rupture without warning, causing fatal clinical events such as myocardial infarction and stroke. ... We discuss the basic mechanics that govern plaque behavior, the material properties of atherosclerotic tissues and the studies ...
http://www.biomedsearch.com/nih/Biomechanical-structural-stresses-atherosclerotic-plaques/20936933.html
*  Multiple Atherosclerotic Plaque Rupture in Acute Coronary Syndrome | Circulation
Multiple atherosclerotic plaque rupture in acute coronary syndrome: a three-vessel intravascular ultrasound study. Circulation ... Multiple atherosclerotic plaque rupture in acute coronary syndrome: a three-vessel intravascular ultrasound study. Circulation ... Unfortunately, the coronary arteriographic appearance of a ruptured plaque does not tell how recently the plaque rupture has ... that plaque rupture is not the usual mechanism for increase in occlusiveness of smooth-appearing atherosclerotic lesions, and ...
http://circ.ahajournals.org/content/107/9/e65
*  Identification of Oxidized Phosphatidylinositols Present in OxLDL and Human Atherosclerotic Plaque | SpringerLink
Phospholipids and oxophospholipids in atherosclerotic plaques at different stages of plaque development. Lipids 39:97-109PubMed ... This is the first identification of OxPtdIns molecules in human OxLDL and atherosclerotic plaque. With these novel molecules ... Hydroxides decreased with increased oxidation achieving a minimum at 24 h (5.2 ± 0.3%). Human atherosclerotic plaques contained ... We sought to identify and quantitate oxidized phosphatidylinositol (OxPtdIns) species in OxLDL and human atherosclerotic plaque ...
https://link.springer.com/article/10.1007/s11745-016-4217-y
*  Chemokine Receptor 7 Knockout Attenuates Atherosclerotic Plaque DevelopmentClinical Perspective | Circulation
CCR7 Deficiency Increases Infiltration of DCs and T Cells in Atherosclerotic Plaques. To identify DCs within atherosclerotic ... Analysis of atherosclerotic plaque development after eating a high-cholesterol diet for 12 weeks. A, En face preparation of ... Atherosclerotic plaque development was analyzed after feeding 10-week-old male mice a high-cholesterol diet for 12 weeks. ... Here, we report that atherosclerotic plaque extent throughout the aorta was profoundly reduced in ccr7−/−/ldlr−/− mice after 12 ...
http://circ.ahajournals.org/content/122/16/1621
*  Atherosclerotic plaque | definition of atherosclerotic plaque by Medical dictionary
What is atherosclerotic plaque? Meaning of atherosclerotic plaque medical term. What does atherosclerotic plaque mean? ... Looking for online definition of atherosclerotic plaque in the Medical Dictionary? atherosclerotic plaque explanation free. ... atherosclerotic plaque. Also found in: Dictionary, Thesaurus, Encyclopedia. atherosclerotic plaque. The core lesion of ... See Complicated plaque. Atherosclerotic plaque. A deposit of fat and other substances that accumulate in the lining of the ...
https://medical-dictionary.thefreedictionary.com/Atherosclerotic+plaque
*  Aldehyde dehydrogenase 2 inhibits inflammatory response and regulates atherosclerotic plaque. - PubMed - NCBI
Changes of atherosclerotic plaques in aortas and carotid plaques composition in apoE−/− mice after lentivirus transfection ... Aldehyde dehydrogenase 2 inhibits inflammatory response and regulates atherosclerotic plaque.. Pan C1,2,3,4, Xing JH1,2,3,4, ... A. Representative en face photographs of aortas in three groups showing oil red O-stained atherosclerotic plaques. B. ... We also found that ALDH2 activity decreased in atherosclerotic plaques of human and aged apoE-/- mice. Moreover, in vitro ...
https://www.ncbi.nlm.nih.gov/pubmed/27191745
*  Numerical observer for atherosclerotic plaque classification in spectral computed tomography
... calcified plaque versus fatty-mixed plaque and (2) calcified plaque versus iodine-mixed blood. MECT outperformed DECT and ... Numerical observer for atherosclerotic plaque classification in spectral computed tomography. Auranuch Lorsakul, Georges El ... We used an extended cardiac-torso anthropomorphic digital phantom and three simulated plaque types (i.e., calcified plaque, ... "Numerical observer for atherosclerotic plaque classification in spectral computed tomography," Journal of Medical Imaging 3(3 ...
https://www.spiedigitallibrary.org/journals/Journal-of-Medical-Imaging/volume-3/issue-3/035501/Numerical-observer-for-atherosclerotic-plaque-classification-in-spectral-computed-tomography/10.1117/1.JMI.3.3.035501.short?SSO=1
*  Atherosclerotic Plaque as Infected Biofilm - One Radio Network
Formation of atherosclerotic plaque tends to occur at sites of injury, such as at bifurcations where shear forces are maximal, ... Atherosclerotic Plaque as Infected Biofilm' has no comments. Be the first to comment this post!. ... Stephen Fry runs his own microbiology lab where he examines high powered views of biofilms in atherosclerotic plaque material ... So, the idea of atherosclerotic plaque as infected biofilm certainly fits the pattern of commonly affected sites in the ...
https://oneradionetwork.com/archive/atherosclerotic-plaque-infected-biofilm/
*  Laser-induced fluorescence of atherosclerotic plaques | (1998) | Moise | Publications | Spie
... fibrous plaque, atherosclerotic plaque, calcified plaque and ulcerated plaque. As for statistics, the total number of ... Laser-induced fluorescence of atherosclerotic plaques Author(s): N. Moise; Mihail-Lucian Pascu; C. Carp; C. Volvoreanu ... we found proeminent differences both in spectral and temporal range between normal artery and atherosclerotic plaques which was ... In vitro laser-induced fluorescence (LIF) spectra and lifetimes of normal and atherosclerotic tissues are reported. The ...
http://spie.org/Publications/Proceedings/Paper/10.1117/12.312652
*  Stationary and high-frequency pulsed electron paramagnetic resonance of a calcified atherosclerotic plaque | SpringerLink
... electron paramagnetic resonance in medicine are demonstrated on an example of the investigation of a calcified atherosclerotic ... After the irradiation of the atherosclerotic plaque by x rays, a new type of paramagnetic centers-organomineral radicals-is ... The spectral and relaxation characteristics of these radicals depend on the calcification degree of the atherosclerotic plaque ... Stationary and high-frequency pulsed electron paramagnetic resonance of a calcified atherosclerotic plaque. ...
https://link.springer.com/article/10.1134%2FS0021364008130158
*  Effects of Crestor on Inflammation of Atherosclerotic Plaques - Tabular View - ClinicalTrials.gov
Effects of Crestor on Inflammation of Atherosclerotic Plaques. The safety and scientific validity of this study is the ... Effects of Crestor on Inflammation of Atherosclerotic Plaques. Official Title ICMJE Exploratory Study of New Imaging Biomarkers ... Subjects with a non-calcified plaque of at least 2 mm over an at least 6 mm length on first MR scan with an uptake of contrast ... The primary aim of this study is to investigate the effect of 40 mg dose of rosuvastatin on carotid plaque inflammation ...
https://clinicaltrials.gov/ct2/show/record/NCT00689416
*  Discordant Lipid Pattern and Carotid Atherosclerotic Plaque. Importance of Remnant Cholesterol
Carotid atherosclerotic plaque was recorded when atherosclerotic plaque was found in the carotid arteries on noninvasive, 2D- ... On the other hand, the diagnosis of carotid atherosclerotic plaque is a surrogate objective and constitutes an independent ... Keywords: Atherosclerosis / complications; Plaque, Atherosclerotic; Carotid Arteries; Cholesterol, LDL; Lipoproteins, LDL; ... increased mean intima-media thickness and more atherosclerotic plaques than patients with low non-HDL-C levels. Moreover, high ...
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2017000600526&lng=en&tlng=en
*  In vivo fluorescence imaging of atherosclerotic plaques - Integrative Biology Blog
The probe was used in vivo to image atherosclerotic plaques in living mice. The fluorescent probe is based on an activatable ... The team hope that probes like this could eventually be used to deliver MRI contrast agents to atherosclerotic plaques to ... In vivo fluorescence imaging of atherosclerotic plaques with activatable cell-penetrating peptides targeting thrombin activity ... The fluorescence intensity varies depending on the severity of the plaque and the histologic grade of the aorta. ...
http://blogs.rsc.org/ib/2012/04/27/in-vivo-fluorescence-imaging-of-atherosclerotic-plaques/
*  Sex Differences in Patients With Asymptomatic Carotid Atherosclerotic Plaque | Stroke
Because plaque rupture is a common precipitating event for thromboembolic events,3-5 CEA to remove atherosclerotic plaque prone ... Atherosclerotic plaque that is prone to rupture because of its intrinsic composition such as intraplaque hemorrhage and a large ... Sex Differences in Patients With Asymptomatic Carotid Atherosclerotic Plaque. In Vivo 3.0-T Magnetic Resonance Study. Hideki ... Sex Differences in Patients With Asymptomatic Carotid Atherosclerotic Plaque. Hideki Ota, Mathew J. Reeves, David C. Zhu, ...
http://stroke.ahajournals.org/content/41/8/1630
*  Human Atherosclerotic Plaque Inflammation Imaged Using PDG-PET/CT - Full Text View - ClinicalTrials.gov
Human Atherosclerotic Plaque Inflammation Imaged Using PDG-PET/CT. The safety and scientific validity of this study is the ... Plaque, Atherosclerotic. Pathologic Processes. Lentivirus Infections. Retroviridae Infections. RNA Virus Infections. Virus ... Tools for detecting and quantifying atherosclerotic pro/regression in people with diabetes and other CVD risk factors lack ... a standard measure of carotid atherosclerotic burden. We propose to obtain pilot data that shows feasibility for a novel ...
https://clinicaltrials.gov/show/NCT00958815?order=318
*  DSpace@MIT: Detection of morphological markers of vulnerable atherosclerotic plaque using multimodal...
Detection of morphological markers of vulnerable atherosclerotic plaque using multimodal spectroscopy. Research and Teaching ... Detection of morphological markers of vulnerable atherosclerotic plaque using multimodal spectroscopy. Download ... "Detection of Morphological Markers of Vulnerable Atherosclerotic Plaque Using Multimodal Spectroscopy." Journal of Biomedical ... Vulnerable plaques, which are responsible for most acute ischemic events, are presently invisible to x-ray angiography. Their ...
http://dspace.mit.edu/handle/1721.1/87654
*  Novel approaches to stabilize atherosclerotic plaques
... Project status: ... atherosclerosis based on local activation of protective anti-inflammatory immune and tissue repair responses in atherosclerotic ...
http://stias.ac.za/research/projects/novel-approaches-to-stabilize-atherosclerotic-plaques/
*  JCI - CAMKIIγ suppresses an efferocytosis pathway in macrophages and promotes atherosclerotic plaque necrosis
Macrophages in necrotic and symptomatic atherosclerotic plaques in humans as well as advanced atherosclerotic lesions in mice ... CAMKIIγ suppresses an efferocytosis pathway in macrophages and promotes atherosclerotic plaque necrosis. ... CAMKIIγ suppresses an efferocytosis pathway in macrophages and promotes atherosclerotic plaque necrosis. ... identify a macrophage CaMKIIγ/ATF6/LXRα/MerTK pathway as a key factor in the development of necrotic atherosclerotic plaques. ...
https://www.jci.org/articles/view/94735/pdf
*  Visualization of atherosclerotic vulnerable plaque
... Super Paramagnetic Iron Oxide As a Contrast Media for MRI Mitra Rajabi, MD ... Visualization of atherosclerotic vulnerable plaque * 1. Visualization of Atherosclerotic Vulnerable Plaque Super Paramagnetic ... Atherosclerotic plaque: Radionucli... by adamsh 629 views * Cardiovascular pathology coronary h... by Ivano-Frankivsk N... ... and intra plaque hemorrhage all of them representing vulnerable plaque may contribute to retaining of USPIO inside the plaque ...
https://www.slideshare.net/SHAPE_Society/visualization-of-atherosclerotic-vulnerable-plaque
*  Role of infrasound pressure waves in atherosclerotic plaque rupture: a theoretical approach.
... in atherosclerotic plaque rupture. Atherosclerotic plaques have been simulated partly, in two dimensions, as being short or ... in atherosclerotic plaque rupture.. METHODS: Atherosclerotic plaques have been simulated partly, in two dimensions, as being ... In future, detection of foci areas and repair (i.e. via Laser Healing Microtechnique) may attenuate atherosclerotic plaque ... has been examined around the simulated plaques.. RESULTS: The incidence of IPW on plaque surface results both in reflection and ...
http://www.biomedsearch.com/nih/Role-infrasound-pressure-waves-in/18221105.html
*  EFFECTS OF FCγRIIIA ON AORTIC ATHEROSCLEROTIC PLAQUE DESTABILISATION IN APOE−/− MICE | Heart
Results Aortic atherosclerotic plaque formation was induced in ApoE−/− mice after feeding on high-fat diet for 10 weeks which ... Thrombosis induced by atherosclerotic plaque destabilisation is the leading cause of the incidence of acute cardiovascular ... The role of FcγRIIIA inhibition by IVIG in atherosclerotic plaque destabilisation in ApoE−/− mice was similar to that with ... FcγRIIIA expression changes in mice with atherosclerotic plaque were determined by assaying the protein level of membrane CD16 ...
http://heart.bmj.com/content/98/Suppl_2/E70.3