Patent US6903098 - Use of phthalazine derivatives - Google Patents  Patent US6903098 - Use of phthalazine derivatives - Google Patents
... these phthalazine derivatives also show a selective inhibition of PARP-homologous enzymes. ... The present invention relates to the use of phthalazine derivatives as inhibitors of the enzyme poly(ADP-ribose) polymerase or ... In addition, the phthalazines I can be beneficial in the chemotherapy of tumors and metastasis thereof and can be used to treat ... The phthalazine derivatives I were measured in this way for an inhibitory effect on the enzyme poly(ADP-ribose) polymerase or ...
more infohttp://www.google.com/patents/US6903098?dq=5,742,768
Biotransformation of quinazoline and phthalazine by Aspergillus niger. | Sigma-Aldrich  Biotransformation of quinazoline and phthalazine by Aspergillus niger. | Sigma-Aldrich
Biotransformation of quinazoline and phthalazine by Aspergillus niger.. [John B Sutherland, Thomas M Heinze, Laura K ... Cultures of Aspergillus niger NRRL-599 in fluid Sabouraud medium were grown with quinazoline and phthalazine for 7 days. ... Quinazoline was oxidized to 4-quinazolinone and 2,4-quinazolinedione, and phthalazine was oxidized to 1-phthalazinone. ...
more infohttps://www.sigmaaldrich.com/catalog/papers/21169055
US3667954A - Tribromomethyl sulfonyl pyridazine or phthalazine photoactivators 
      - Google Patents  US3667954A - Tribromomethyl sulfonyl pyridazine or phthalazine photoactivators - Google Patents
CHARACTERRIZED BY USING AS THE PHOTO-ACTIVATOR A PYRIDAZINE OR PHTHALAZINE DERIVATIVE WHICH IS REPRESENTED BY THE GENERAL ... Tribromomethyl sulfonyl pyridazine or phthalazine photoactivators Download PDF Info. Publication number. US3667954A. US3667954A ... b) phthalazine derivatives of the formula: wherein R is hydrogen, hydroxy, lower alkyl, alkylsulfonyl, alkoxy, or ... US3667954A 1969-04-21 1970-04-22 Tribromomethyl sulfonyl pyridazine or phthalazine photoactivators Expired - Lifetime ...
more infohttps://patents.google.com/patent/US3667954A/en
Phthalazine Global Market and Forecast Research : ReportsnReports  Phthalazine Global Market and Forecast Research : ReportsnReports
65 Pages Report] Check for Discount on Phthalazine Global Market and Forecast Research report by ChemReport. DescriptionWe ... The price of Phthalazine in 2016 Major end users of Phthalazine Potential users of Phthalazine The main trading companies of ... Phthalazine Global Market and Forecast Research Table of Contents Part 1: General Information of Phthalazine Chapter 1: ... 2.2 Construction of Industry Chain of Phthalazine Chapter 3: End User of Phthalazine List of Tables Manufacturers and ...
more infohttp://www.reportsnreports.com/reports/678247-phthalazine-global-market-and-forecast-research.html
Phthalazine - Wikipedia  Phthalazine - Wikipedia
Phthalazine can be obtained by the condensation of w-tetrabromorthoxylene with hydrazine, or by the reduction of ... Phthalazine, also called benzo-orthodiazine or benzopyridazine, is a heterocyclic organic compound with the molecular formula ...
more infohttps://en.wikipedia.org/wiki/Phthalazine
Discovery of a potent, selective, and orally bioavailable pyridinyl-pyrimidine phthalazine aurora kinase inhibitor.  - PubMed -...  Discovery of a potent, selective, and orally bioavailable pyridinyl-pyrimidine phthalazine aurora kinase inhibitor. - PubMed -...
Converting the internally hydrogen-bonded six-membered pseudo-ring of the anthranilamide to a phthalazine (8a-b) led to a ... Discovery of a potent, selective, and orally bioavailable pyridinyl-pyrimidine phthalazine aurora kinase inhibitor.. Cee VJ1, ...
more infohttps://www.ncbi.nlm.nih.gov/pubmed/20684549
Pentaerythritol as efficient H- bonding organocatalyst for synthesis of indazolo[2,1- b]phthalazine-trione derivatives |...  Pentaerythritol as efficient H- bonding organocatalyst for synthesis of indazolo[2,1- b]phthalazine-trione derivatives |...
Biodegradable H-bonding organocatalyst Indazolo[2,1-b]phthalazine-triones Nontoxic Organocatalyst Pentaerythritol Solvent-free ... Pentaerythritol as efficient H-bonding organocatalyst for synthesis of indazolo[2,1-b]phthalazine-trione derivatives. ... phthalazine-trione derivatives via one-pot three-component condensation of aromatic aldehydes, phthalhydrazide, and dimedone ...
more infohttps://link.springer.com/article/10.1007%2Fs11164-019-03821-4
Carboxylate-bridged diiron(II) complexes with a sterically hindered phthalazine ligand  - Zurich Open Repository and Archive  Carboxylate-bridged diiron(II) complexes with a sterically hindered phthalazine ligand - Zurich Open Repository and Archive
Download PDF 'Carboxylate-bridged diiron(II) complexes with a sterically hindered phthalazine ligand'. Item availability may be ... complexes with a sterically hindered phthalazine ligand. Inorganica Chimica Acta, 337:212-222. ...
more infohttps://www.zora.uzh.ch/id/eprint/65619/
1,2-Dihydro-2-(p-tolylsulfonyl)phthalazine - Alfa Chemistry  1,2-Dihydro-2-(p-tolylsulfonyl)phthalazine - Alfa Chemistry
... phthalazine/ACM17802403 can be provided in Alfa Chemistry. We are dedicated to provide our customers the best products and ... Home > Product > Heterocyclic Organic Compound > 1,2-Dihydro-2-(p-tolylsulfonyl)phthalazine ...
more infohttp://www.alfa-chemistry.com/cas_17802-40-3.htm
PHTHALAZINE-CONTAINING ANTIDIABETIC COMPOUNDS - Patent application  PHTHALAZINE-CONTAINING ANTIDIABETIC COMPOUNDS - Patent application
0097] In another embodiment, the present invention discloses phthalazine compounds of Formula I of the formula ##STR00031## or ... Patent application title: PHTHALAZINE-CONTAINING ANTIDIABETIC COMPOUNDS. Inventors: Jason L. Davis (Albany, NY, US) Michael ... 0002] The present invention relates to certain phthalazine-containing compounds that are agonists of the G-protein coupled ... This invention provides for certain phthalazine-containing compounds of the formula (I) or a pharmaceutically acceptable salt, ...
more infohttp://www.patentsencyclopedia.com/app/20120004234
Synthesis and Biological Screening of 4-Benzyl-2H-phthalazine Derivatives - pdf descargar  Synthesis and Biological Screening of 4-Benzyl-2H-phthalazine Derivatives - pdf descargar
Synthesis and Biological Screening of 4-Benzyl-2H-phthalazine Derivatives. . Biblioteca virtual para leer y descargar libros, ... Keywords: phthalazine derivatives; anthracene derivatives; synthesis; antimicrobial activity phthalazine derivatives; ... Synthesis and Biological Screening of 4-Benzyl-2H-phthalazine Derivatives - Descarga este documento en PDF. Documentación en ...
more infohttp://libros.duhnnae.com/2017/jun5/149753594517-Synthesis-and-Biological-Screening-of-4-Benzyl-2H-phthalazine-Derivatives.php
Simultaneous Determination of Sulfamethoxazole and Phthalazine by HPLC and Multivariate Calibration Methods  Simultaneous Determination of Sulfamethoxazole and Phthalazine by HPLC and Multivariate Calibration Methods
... and Phthalazine (PHZ) by High Performance Liquid Chromatography (HPLC). Multivariate calibration techniques such as Classical ... Asadi, S., Gharbani, P. Simultaneous Determination of Sulfamethoxazole and Phthalazine by HPLC and Multivariate Calibration ... Asadi, S., Gharbani, P. (2013). Simultaneous Determination of Sulfamethoxazole and Phthalazine by HPLC and Multivariate ... "Simultaneous Determination of Sulfamethoxazole and Phthalazine by HPLC and Multivariate Calibration Methods". Iranian Journal ...
more infohttp://www.ijcce.ac.ir/article_5847.html
Synthesis of new analogs of 3-methyl-[1,2,4] triazolo [3,4-a] phthalazines via Suzuki coupling and evaluation of their...  Synthesis of new analogs of 3-methyl-[1,2,4] triazolo [3,4-a] phthalazines via Suzuki coupling and evaluation of their...
... phthalazines via Suzuki coupling and evaluation of their anticancer and antimicrobial activity ... C. K. Ryu, E. R. Park, Mi-Young Ma, Ji-HeeNho, Synthesis and antifungal activity of 6-arylamino-phthalazine-5,8-diones and 6,7- ... A series of new N-aryl substituted phenyl acetamide analogs of 3-methyl-[1,2,4] triazolo[3,4-a] phthalazines were synthesized ... Synthesis of new analogs of 3-methyl-[1,2,4] triazolo [3,4-a] phthalazines via Suzuki coupling and evaluation of their ...
more infohttp://medjchem.com/index.php/medjchem/article/view/869
Electro-Organic Synthesis: An Efficient Method for the Preparation of Nanosized Particles of Phthalazine Derivatives via One...  Electro-Organic Synthesis: An Efficient Method for the Preparation of Nanosized Particles of Phthalazine Derivatives via One...
This contribution describes an electrochemical approach for the preparation of nanosized particles of phthalazine in high ... "Electro-Organic Synthesis: An Efficient Method for the Preparation of Nanosized Particles of Phthalazine Derivatives via One- ... Electro-Organic Synthesis: An Efficient Method for the Preparation of Nanosized Particles of Phthalazine Derivatives via One- ... This contribution describes an electrochemical approach for the preparation of nanosized particles of phthalazine in high ...
more infohttp://www.analchemres.org/article_10300.html
Heterocyclic Communications  Heterocyclic Communications
Efficient synthesis of selected phthalazine derivatives. Bunce, Richard A. / Harrison, Todd / Nammalwar, Baskar ...
more infohttps://www.degruyter.com/view/j/hc.2012.18.issue-3/issue-files/hc.2012.18.issue-3.xml
Search | The Merck Index Online  Search | The Merck Index Online
The Merck Index* Online - search across all of the entries using text (names, classifications) and numerical (melting point, mol weight, boiling point) queries
more infohttps://www.rsc.org/Merck-Index/search
Patent US7524621 - Method of preparing silver carboxylate soaps - Google Patents  Patent US7524621 - Method of preparing silver carboxylate soaps - Google Patents
Phthalazine and phthalazine derivatives [such as those described in U.S. Pat. No. 6,146,822 (Asanuma et al.)], phthalazinone, ...
more infohttp://www.google.com/patents/US7524621?dq=5,664,133
BRCA1 | Cancer Genetics Web  BRCA1 | Cancer Genetics Web
Germline mutations in BRCA1 gene have been reported in up to 20 % of epithelial ovarian cancer (EOC) patients. Distinct clinical characteristics have been attributed to this special EOC population. We hypothesized that mutations in different BRCA1 gene exons may differently affect the clinical course of the disease. The aim of this study was to analyze, in a large cohort of primary EOCs, the clinical impact of mutations in BRCA1 gene exon 11, the largest exon of the gene sequence encoding the 60 % of BRCA1 protein. Two hundred sixty-three primary EOC patients, treated between 2000 and 2008 at Charité University Hospital of Berlin, were included. Patients' blood samples were obtained from the Tumor Ovarian Cancer (TOC) Network ( www.toc-network.de ). Direct sequencing of BRCA1 gene exon 11 was performed for each patient to detect mutations. Based on their BRCA1 exon 11 mutational status, patients were compared regarding clinico-pathological variables and survival. Mutations in BRCA1 exon 11 were ...
more infohttp://www.cancerindex.org/geneweb/BRCA1.htm
Molecules | Free Full-Text | Microwave Assisted Reactions of Some Azaheterocylic Compounds  Molecules | Free Full-Text | Microwave Assisted Reactions of Some Azaheterocylic Compounds
The N-alkylation reactions of imidazole, pyrimidine, pyridazine and phthalazine have been studied. The microwaves remarkably ... Keywords: Microwave N-alkylation; Imidazole; Pyrimidine; Pyridazine; Phthalazine Microwave N-alkylation; Imidazole; Pyrimidine ... The N-alkylation reactions of imidazole, pyrimidine, pyridazine and phthalazine have been studied. The microwaves remarkably ...
more infohttp://www.mdpi.com/1420-3049/14/1/403
Vatalanib - DrugBank  Vatalanib - DrugBank
This compound belongs to the class of organic compounds known as phthalazines. These are compounds containing a phthalazine ... Phthalazine / Aniline or substituted anilines / Aminopyridazine / Chlorobenzene / Halobenzene / Aryl chloride / Aryl halide / ... Phthalazines. Alternative Parents. Aniline and substituted anilines / Chlorobenzenes / Aminopyridazines / Pyridines and ...
more infohttps://www.drugbank.ca/drugs/DB04879
US4868179A - Method of reducing mortality associated with congestive heart failure using hydralazine and isosorbide dinitrate 
...  US4868179A - Method of reducing mortality associated with congestive heart failure using hydralazine and isosorbide dinitrate ...
Substituted phthalazines US4361564A (en) * 1978-11-30. 1982-11-30. Edwards K David G. Renoprotective treatments employing ... Substituted phthalazines US4361564A (en) * 1978-11-30. 1982-11-30. Edwards K David G. Renoprotective treatments employing ...
more infohttps://patents.google.com/patent/US4868179A/en
Plus it  Plus it
The apparent Km value of phthalazine for human liver cytosol used was 24.9 µM, and phthalazine was incubated at 10 µM with ... Inhibitory Activities for Phthalazine Oxidation to Phthalazone in Human Liver Cytosol.. The incubation mixture consisted of 25 ... AO activity measured as the oxidation of phthalazine to phthalazone was not inhibited by lenvatinib, M2′, or M3′ in human liver ... Samples were prepared in triplicate, and the AO reaction was initiated by the addition of phthalazine to obtain a final ...
more infohttp://dmd.aspetjournals.org/content/42/8/1326