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*  The role of His66 and His72 in the reaction mechanism of bovine liver low-M(r) phosphotyrosine protein phosphatase. | IRIS...
The role of His66 and His72 in the reaction mechanism of bovine liver low-M(r) phosphotyrosine protein phosphatase. ... Site-directed mutagenesis of a synthetic gene coding for low-M(r) phosphotyrosine protein phosphatase from bovine liver has ... The role of His66 and His72 in the reaction mechanism of bovine liver low-M(r) phosphotyrosine protein phosphatase. ... Site-directed mutagenesis of a synthetic gene coding for low-M(r) phosphotyrosine protein phosphatase from bovine liver has ...
https://flore.unifi.it/handle/2158/312981
*  Hypoxic Induction of the Hypoxia-Inducible Factor Is Mediated via the Adaptor Protein Shc in Endothelial Cells | Circulation...
Subsequently, Western blot analysis was performed with anti-phosphotyrosine antibodies. Data are mean±SEM (n=4). P,0.05 for ... Western blot analysis using anti-phosphotyrosine antibodies revealed significantly increased tyrosine phosphorylation of the ... anti-phosphotyrosine from Upstate Technology, 1:500; and anti-myc from Santa Cruz, 1:250) at 4°C overnight and secondary ... an amino-terminal phosphotyrosine binding domain, a central collagen homology domain, and a carboxy-terminal Src homology 2 ...
http://circres.ahajournals.org/content/91/1/38
*  Phosphopeptide Enrichment Spin Columns
Enrich for any type of phosphopeptide-phosphotyrosine, phosphoserine, or phosphothreonine *Obtain increased sensitivity in mass ...
http://www.clontech.com/US/Products/Protein_Expression_and_Purification/Purify_Phospho-_and_Glycoproteins/Phosphopeptide_Spin_Columns
*  PTPN1 (protein tyrosine phosphatase, non-receptor type 1)
... by dephosphorylating phospho-tyrosines of the scaffold protein GAB1. These phospho-tyrosines are the docking sites of the ERK ... PTP1B, in fact, dephosphorylates activating phospho-tyrosines present on the Insulin receptor molecule (INSR; OMIM 147670) in ... Troglitazone activates PTP1B, which subsequently reduces phosphotyrosine 705 in the prosurvival protein STAT3. Reduction of ... association since it is bound to the cytoplasmic domain of N-cadherin and it is responsible for dephosphorylating phospho-tyrosine ...
http://atlasgeneticsoncology.org/Genes/PTPN1ID41909ch20q13.html
*  Phosphotyrosine-binding domain - Wikipedia
In molecular biology, Phosphotyrosine-binding domains are protein domains which bind to phosphotyrosine. The phosphotyrosine- ... The phosphotyrosine-binding domain of insulin receptor substrate-1 is not related to the phosphotyrosine-binding domain of ... Two arginines in this domain are responsible for hydrogen bonding phosphotyrosine residues on an Ac-LYASSNPApY-NH2 peptide in ... Insulin receptor substrate-1 proteins contain both a pleckstrin homology domain and a phosphotyrosine binding (PTB) domain. The ...
https://en.wikipedia.org/wiki/Phosphotyrosine-binding_domain
*  The phosphotyrosine binding-like ... preview & related info | Mendeley
A molecular model of talin F3 indicated that it resembles a phosphotyrosine-binding (PTB) domain. PTB domains recognize peptide ...
https://www.mendeley.com/research-papers/phosphotyrosine-bindinglike-domain-talin-activates-integrins/
*  Anti-Phosphotyrosine antibody (HRP) (ab17301) | Abcam
Rabbit polyclonal Phosphotyrosine antibody conjugated to HRP. Validated in WB, ELISA and tested in Species independent. ... Specific to phosphotyrosine-containing proteins. It has minimal or no reactivity with phosphothreonine or phosphoserine- ...
https://www.abcam.com/phosphotyrosine-antibody-hrp-ab17301.html
*  Phospho Tyrosine Hydroxylase (S19) antibody (ab51194) | Abcam
Rabbit polyclonal Tyrosine Hydroxylase (phospho S19) antibody. Validated in ELISA, IHC and tested in Human. Immunogen corresponding to synthetic peptide.
https://www.abcam.com/tyrosine-hydroxylase-phospho-s19-antibody-ab51194.html
*  PE anti-Phosphotyrosine Antibody anti-Phosphotyrosine - PY20
PE anti-Phosphotyrosine Antibody - Phosphorylation is a common modification of proteins that can result in alterations in ... KLH-conjugated phosphotyrosine Formulation Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. Preparation The ... The cells were then fixed with 2% paraformaldehyde, permeabilized with 90% methanol and stained with anti-phosphotyrosine ( ... The cells were then fixed with 2% paraformaldehyde, permeabilized with 90% methanol and stained with anti-phosphotyrosine ( ...
https://www.biolegend.com/en-us/products/pe-anti-phosphotyrosine-antibody-13057
*  Patent US4543439 - Production and use of monoclonal antibodies to phosphotyrosine-containing ... - Google Patents
The antibodies, which have demonstrated affinity for a variety of molecules containing o-phosphotyrosine residues, were ... biological reagent useful in biological/medical research for isolating and identifying phosphotyrosine-containing proteins. In ... phosphotyrosine analogs and phosphotyrosine-containing proteins, forming fused cell hybrids between antibody-producing cells ... which antibodies demonstrate specificity for a phosphotyrosine moiety on phosphotyrosine-containing proteins; and testing for ...
http://www.google.ca/patents/US4543439
*  anti-Phosphotyrosine (phosphorylated) antibody (Biotin)</span...
anti-Phosphotyrosine (phosphorylated) antibody (Biotin) Phosphotyrosine (phosphorylated) antibody (Biotin). Details for Product ... Phosphotyrosine can be detected through specific antibodies, and are helpful in facilitating the identification of tyrosine ...
http://www.antibodies-online.com/antibody/264884/anti-Phosphotyrosine+phosphorylated+antibody+Biotin/
*  Phosphotyrosine Monoclonal Mouse Antibody (PY20) | Biotium
Antibody to phosphotyrosine provides an excellent tool for the detection, characterization, and purification of phosphotyrosine ... Catalog number key for antibody number 0232, Anti-Phosphotyrosine (PY20) The prefix indicates conjugation, followed by the ...
https://biotium.com/product/monoclonal-anti-phosphotyrosine-py20/
*  Phospho-Tyrosine Antibody (G104) [DyLight 350] (NBP1-47562UV): Novus Biologicals
Phospho-Tyrosine Antibody (G104) [DyLight 350] Summary. Immunogen. Phosphotyrosine, alanine and glyceine in a 1:1:1 ratio ... Blogs on Phospho-Tyrosine. There are no specific blogs for Phospho-Tyrosine, but you can read our latest blog posts. ... Reviews for Phospho-Tyrosine Antibody (NBP1-47562UV) (0) There are no reviews for Phospho-Tyrosine Antibody (NBP1-47562UV). By ... Publications for Phospho-Tyrosine Antibody (NBP1-47562UV) (0). There are no publications for Phospho-Tyrosine Antibody (NBP1- ...
https://www.novusbio.com/products/phospho-tyrosine-antibody-g104_nbp1-47562uv
*  Association of beta 1 integrin with phosphotyrosine in growth cone filopodia | Journal of Neuroscience
Association of beta 1 integrin with phosphotyrosine in growth cone filopodia. DY Wu, LC Wang, CA Mason and DJ Goldberg ... Association of beta 1 integrin with phosphotyrosine in growth cone filopodia Message Subject (Your Name) has forwarded a page ... beta 1 integrin and phosphotyrosine are known to colocalize at focal contacts, sites of adhesion of cells to the extracellular ... Use of an inhibitor of protein-tyrosine kinases to deplete tip phosphotyrosine also caused disappearance of beta 1 integrin ...
http://www.jneurosci.org/content/16/4/1470
*  Gene Expression Profiles of Human Phosphotyrosine Phosphatases Consequent to Th1 Polarisation and Effector Function
... Patricia ... "Rapid activation of the T-cell tyrosine protein kinase pp56lck by the CD45 phosphotyrosine phosphatase," Proceedings of the ...
https://www.hindawi.com/journals/jir/2017/8701042/ref/
*  Assembly and analysis of a comprehensive phosphotyrosine-dependent protein-protein interaction network
This study provides a comprehensive set of 292 mostly novel, high-quality phosphotyrosine- dependent protein-protein ... monolithic network with a central core and reflect and expand phosphotyrosine-related KEGG pathways. Seven of the eight core ... interactions detected in genome-scale yeast two-hybrid screens using full-length proteins filling a gap in phosphotyrosine ...
https://edoc.hu-berlin.de/handle/18452/18127
*  Neutral Loss Is a Very Common Occurrence in Phosphotyrosine-Containing Peptides Labeled with Isobaric Tags. - PubMed - NCBI
Neutral Loss Is a Very Common Occurrence in Phosphotyrosine-Containing Peptides Labeled with Isobaric Tags.. Everley RA1,2, ... a) Comparison of the average phosphotyrosine immonium ion intensity (relative to the base peak) in terms of proton mobility, ... The MS3 spectrum clearly shows the presence of the phosphotyrosine immonium ion, allowing localization of the site to tyrosine. ... Comparing the extent of neutral loss formation for five different conditions using the 2000 member phosphotyrosine library. A ...
https://www.ncbi.nlm.nih.gov/pubmed/27978624
*  Structure Cluster - 1IJR: Crystal structure of LCK SH2 complexed with nonpeptide phosphotyrosine mimetic 3D...
A novel phosphotyrosine mimetic 4'-carboxymethyloxy-3'-phosphonophenylalanine (Cpp): exploitation in the design of nonpeptide ...
http://www.rcsb.org/pdb/explore/structureCluster.do?structureId=1IJR
*  Anti-phosphotyrosine receptor antibody (P-Tyr RTK) arra | Open-i
Anti-phosphotyrosine receptor antibody (P-Tyr RTK) array analysis of 4T1 cells and tumors. (A-B) P-RTK analysis on lysates of ... Figure 4: Anti-phosphotyrosine receptor antibody (P-Tyr RTK) array analysis of 4T1 cells and tumors. (A-B) P-RTK analysis on ... Figure 4: Anti-phosphotyrosine receptor antibody (P-Tyr RTK) array analysis of 4T1 cells and tumors. (A-B) P-RTK analysis on ... To approach this, we used anti-phosphotyrosine receptor antibody arrays (P-Tyr RTK) to screen for activity across a panel of ...
https://openi.nlm.nih.gov/detailedresult.php?img=PMC3672810_bcr3379-4&req=4
*  APPL2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 [Meleagris gallopavo (turkey)] - Gene -...
adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. See related. Ensembl:ENSMGAG00000012895 Gene ... APPL2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 [ Meleagris gallopavo (turkey) ] Gene ID ... Phosphotyrosine-binding (PTB) domain. cd13247. Location:209 → 333. BAR-PH_APPL; Adaptor protein containing PH domain, PTB ... Phosphotyrosine-binding (PTB) domain. cd13247. Location:165 → 289. BAR-PH_APPL; Adaptor protein containing PH domain, PTB ...
https://www.ncbi.nlm.nih.gov/gene?cmd=Retrieve&dopt=Graphics&list_uids=100545199
*  Mitotic phosphotyrosine network analysis reveals that tyrosine phosphorylation regulates Polo-like kinase 1 (PLK1) | Science...
However, mitotic phosphotyrosine is not well characterized. Although a few functionally-relevant mitotic phosphotyrosine sites ... Mitotic phosphotyrosine network analysis reveals that tyrosine phosphorylation regulates Polo-like kinase 1 (PLK1) ... Mitotic phosphotyrosine network analysis reveals that tyrosine phosphorylation regulates Polo-like kinase 1 (PLK1) ... Mitotic phosphotyrosine network analysis reveals that tyrosine phosphorylation regulates Polo-like kinase 1 (PLK1) ...
https://stke.sciencemag.org/content/9/458/rs14
*  Quantitative Phosphotyrosine Profiling of Patient-Derived Xenografts Identifies Therapeutic Targets in Pediatric Leukemia |...
Using this quantitative phosphotyrosine method, we mapped in total 1,912 class I phosphosites (1,375 phosphotyrosine, 376 ... Using the phosphotyrosine immunoaffinity profiling method, we identified 540 Class I phosphotyrosine sites along with 61 ... Quantitative phosphotyrosine profiling. To compare phosphotyrosine profiles across multiple PDXs, we undertook developing a ... The phosphotyrosine sites of the TKs identified either in T-ALL or in the BCP-ALL PDXs are listed in Supplementary Table S2. ...
http://cancerres.aacrjournals.org/content/76/9/2766
*  Remediated Sequence - 1PH0: Non-carboxylic Acid-Containing Inhibitor of PTP1B Targeting the Second Phosphotyrosine...
Targeting the Second Phosphotyrosine Binding Site with Non-Carboxylic Acid-Containing Ligands. ... Non-carboxylic Acid-Containing Inhibitor of PTP1B Targeting the Second Phosphotyrosine Site. ...
http://www.rcsb.org/pdb/explore/remediatedSequence.do?structureId=1PH0
*  Abstract #4772: 3-D pharmacophore identification of second generation inhibitors of Stat3 SH2-phosphotyrosine binding that...
Abstract #4772: 3-D pharmacophore identification of second generation inhibitors of Stat3 SH2-phosphotyrosine binding that ... Abstract #4772: 3-D pharmacophore identification of second generation inhibitors of Stat3 SH2-phosphotyrosine binding that ... Abstract #4772: 3-D pharmacophore identification of second generation inhibitors of Stat3 SH2-phosphotyrosine binding that ... Abstract #4772: 3-D pharmacophore identification of second generation inhibitors of Stat3 SH2-phosphotyrosine binding that ...
http://cancerres.aacrjournals.org/content/69/9_Supplement/4772.article-info