Glycogen phosphorylase is one of the phosphorylase enzymes (EC 2.4.1.1). Glycogen phosphorylase catalyzes the rate-limiting ... Phosphorylase a and phosphorylase b each exist in two forms a T (tense) inactive state and R (relaxed) state. Phosphorylase b ... Phosphorylase. The crystal structure of the rabbit muscle glycogen phosphorylase-AMP complex. AMP allosteric site (yellow), ... The structural change associated with phosphorylation, and with the conversion of phosphorylase b to phosphorylase a, is the ...
Purine Nucleoside Phosphorylase), Authors: Rafig Gurbanov, Sinem Tunçer. Published in: Atlas Genet Cytogenet Oncol Haematol. ... Nucleoside_phosphorylase_d Nucleoside_phosphorylase_sf Pur_Nuc_Pase_Ino/Guo-sp Purine_phosphorylase Purine_phosphorylase-2_CS ... nucleoside binding purine nucleobase binding purine-nucleoside phosphorylase activity purine-nucleoside phosphorylase activity ... nucleoside binding purine nucleobase binding purine-nucleoside phosphorylase activity purine-nucleoside phosphorylase activity ...
Structure and expression of barley starch phosphorylase genes.. Ma, J., Jiang, Q.-T., Zhang, X., Lan, X.-J., Pu, Z.-E., Wei, Y ... In this study, we isolated starch phosphorylase genes (Pho1 and Pho2) from barley, characterized their gene and protein ... The function of starch phosphorylase has long been debated on the regulation of starch metabolism during the growth and ... Our results provide valuable information to genetically manipulate phosphorylase genes and to further elucidate their ...
View source for Purine nucleoside phosphorylase deficiency. ← Purine nucleoside phosphorylase deficiency. Jump to: navigation, ... NOTOC__ {{Infobox_Disease , Name = Purine nucleoside phosphorylase deficiency , Image = , Caption = , DiseasesDB = 11044 , ... purine nucleoside phosphorylase]]. This enzyme is important in the purine degradation pathway. A deficiency of it causes [[T- ... purine nucleoside phosphorylase]], a key enzyme in the purine salvage pathway. This enzyme is required for [[purine]] ...
Inhibition of purine nucleoside phosphorylase by 8-aminoguanosine: selective toxicity for T lymphoblasts ... Inhibition of purine nucleoside phosphorylase by 8-aminoguanosine: selective toxicity for T lymphoblasts ... Inhibition of purine nucleoside phosphorylase by 8-aminoguanosine: selective toxicity for T lymphoblasts ... Inhibition of purine nucleoside phosphorylase by 8-aminoguanosine: selective toxicity for T lymphoblasts ...
The resulting di-, tri- and macro-primers were incubated with potato phosphorylase and glycogen branching enzyme from ... Potato phosphorylase is able to synthesize linear polyglucans from maltoheptaose primers. By coupling maltoheptaose to butane ... Potato phosphorylase is able to synthesize linear polyglucans from maltoheptaose primers. By coupling maltoheptaose to butane ... The resulting di-, tri- and macro-primers were incubated with potato phosphorylase and glycogen branching enzyme from ...
Inhibitory activity of compound against human purine nucleoside phosphorylase (PNP). ...
Purine nucleoside phosphorylase (PNP) in mammalian tissue is an enzyme responsible for formation of purine bases in DNA. It is ... Effects of some modulators on purine nucleoside phosphorylase activity in myocardial tissue. Åberg, Anna-Maja ... Analytical chemistry, myocardium, purine-nucleoside phosphorylase, enzyme activity, myocardial ischemia National Category ...
β-deuterium kinetic isotope effects in the purine nucleoside phosphorylase reaction. X M Guo, M Ashwell, M L Sinnott, T A ... β-deuterium kinetic isotope effects in the purine nucleoside phosphorylase reaction. X M Guo, M Ashwell, M L Sinnott, T A ... β-deuterium kinetic isotope effects in the purine nucleoside phosphorylase reaction Message Subject (Your Name) has forwarded a ... for phosphorolysis of this compound by the purine nucleoside phosphorylase of Escherichia coli as a function of pH. 3. The pH ...
Human polynucleotide phosphorylase (hPNPaseold-35): a potential link between aging and inflammation. Cancer Res. 64:7473-7478. ... Polynucleotide phosphorylases are highly conserved across species ranging from bacteria and plants to mammals (23). They have a ... Defining the Domains of Human Polynucleotide Phosphorylase (hPNPaseOLD-35) Mediating Cellular Senescence. Devanand Sarkar, Eun ... Human polynucleotide phosphorylase, hPNPase, is localized in mitochondria. J. Mol. Biol. 329:853-857. ...
Thymidine phosphorylase/platelet-derived endothelial cell growth factor (TPase/PD-ECGF) is a catabolic enzyme that has been ... Expression and localization of thymidine phosphorylase/platelet-derived endothelial cell growth factor in skin and cutaneous ... Expression and localization of thymidine phosphorylase/platelet-derived endothelial cell growth factor in skin and cutaneous ...
Glycogen phosphorylase kinase deficiency (disorder),Glycogen phosphorylase kinase deficiency, X-linked,Glycogen phosphorylase ... Hepatic phosphorylase deficiency,Hepatic phosphorylase kinase deficiency,Hers disease,Liver phosphorylase deficiency,Muscle ... Hepatic glycogen phosphorylase deficiency,Hepatic glycogen phosphorylase kinase deficiency,Hepatic glycogen phosphorylase ... Cardiac glycogen phosphorylase kinase deficiency,Cardiac glycogen phosphorylase kinase deficiency (disorder),Danon disease, ...
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Purine-Nucleoside Phosphorylase Deficiency (PNP deficiency): Read more about Symptoms, Diagnosis, Treatment, Complications, ... Purine nucleoside phosphorylase deficiency in a patient with spastic paraplegia and recurrent infections. J Child Neurol. 2007 ... Deficiency of purine nucleoside phosphorylase (PNP) was detected in a 3-yr-old boy who was admitted for investigation of a ... Can, S. and Ozkinay, C. (2007) Purine nucleoside phosphorylase deficiency in a patient with spastic paraplegia and recurrent ...
abstract = "Purine nucleoside phosphorylase (PNP) catalyzes N-ribosidic bond phosphorolysis in 6-oxypurine nucleosides and ... N2 - Purine nucleoside phosphorylase (PNP) catalyzes N-ribosidic bond phosphorolysis in 6-oxypurine nucleosides and ... AB - Purine nucleoside phosphorylase (PNP) catalyzes N-ribosidic bond phosphorolysis in 6-oxypurine nucleosides and ... Purine nucleoside phosphorylase (PNP) catalyzes N-ribosidic bond phosphorolysis in 6-oxypurine nucleosides and deoxynucleosides ...
Crystal structure of human purine nucleoside phosphorylase complexed with acyclovir. Author(s): *dos Santos, D. M. ... In human, purine nucleoside phosphorylase (HsPNP) is responsible for degradation of deoxyguanosine and genetic deficiency of ...
Amide-1,2,3-triazole bioisosterism: the glycogen phosphorylase case. Author/Creator: Chrysina, Evangelia D.. Bokor, Eva. ... the glycogen phosphorylase case," Tetrahedron: Asymmetry, vol. 20, no. 6-8, pp. 733-740, May 2009. ... 3-triazoles which were evaluated as inhibitors of rabbit muscle glycogen phosphorylase b. Pairs of amides versus triazoles with ...
The selective expression of Escherichia coli purine nucleoside phosphorylase (PNP) in solid tumors has been successfully used ... Antitumor activity of 2-fluoro-2′-deoxyadenosine against tumors that express Escherichia coli purine nucleoside phosphorylase ...
An essential function for the phosphate-dependent exoribonucleases RNase PH and polynucleotide phosphorylase. Journal of ... Escherichia coli cells lacking both polynucleotide phosphorylase (PNPase) and RNase PH, the only known P1-dependent ... An essential function for the phosphate-dependent exoribonucleases RNase PH and polynucleotide phosphorylase. / Zhou, Zhihua; ... N2 - Escherichia coli cells lacking both polynucleotide phosphorylase (PNPase) and RNase PH, the only known P1-dependent ...
Crystal structure of the hexameric purine nucleoside phosphorylase from Bacillus subtilis in complex with 2-deoxyguanosine ... Crystal structure of the hexameric purine nucleoside phosphorylase from Bacillus subtilis in complex with 2-deoxyguanosine. ...
Crystal structure of calf spleen purine nucleoside phosphorylase complexed to a novel purine analogue (2007). *Authors: * ... Crystal structure of calf spleen purine nucleoside phosphorylase complexed to a novel purine analogue. FEBS Letters, Amsterdam ... The crystal structures of the enzyme purine nucleotide phosphorylase from schistosoma mansoni refined at 2.75 and 1.75 ... Crystal structure of calf spleen purine nucleoside phosphorylase complexed to a novel purine analogue. FEBS Letters. 2007 ; 581 ...
Purine Nucleoside PhosphorylaseHuman EnzymeUridine PhosphorylaseRibose SugarSide Chain Oxygen Atom ... Johansson M: Identification of a novel human uridine phosphorylase. Biochem Biophys Res Commun 2003, 307: 41-46.View Article ... Burling FT, Kniewel R, Buglino JA, Chadha T, Beckwith A, Lima CD: Structure of Escherichia coli uridine phosphorylase at 2.0 Å. ... Watanabe S, Uchida T: Cloning and expression of human uridine phosphorylase. Biochem Biophys Res Commun 1995, 216: 265-272.View ...
Crystal Structure of Schistosoma Mansoni Purine Nucleoside Phosphorylase Complexed With A Novel Monocyclic Inhibitor ... The binding sites of Bromine atom in the structure of Crystal Structure of Schistosoma Mansoni Purine Nucleoside Phosphorylase ... Bromine in the structure of Crystal Structure of Schistosoma Mansoni Purine Nucleoside Phosphorylase Complexed With A Novel ...
... a structural explanation for the kinetic observations that glucose 6-phosphate inhibition of AMP activation of phosphorylase b ... jats:p,The binding to glycogen phosphorylase b of glucose 6-phosphate and inorganic phosphate (respectively allosteric ... jats:p,The binding to glycogen phosphorylase b of glucose 6-phosphate and inorganic phosphate (respectively allosteric ... Allosteric interactions of glycogen phosphorylase b. A crystallographic study of glucose 6-phosphate and inorganic phosphate ...
The phosphorylase, the rate limiting enzyme of glycogenolysis, is activated by a cascade of enzymatic reactions related to ... This disease is a result of a deficiency of hepatic phosphorylase kinase (PHK), which plays an important role in glycogen ... GSD-IXa is caused by the functional deficiency of the α subunit of phosphorylase kinase (PHK), which activates the ... Willems PJ, Gerver WJ, Berger R, Fernandes J (1990) The natural history of liver glycogenosis due to phosphorylase kinase ...