DiseasesChemicals and Drugs
Phosphoribosyl PyrophosphateRibose-Phosphate PyrophosphokinasePentosephosphatesRibosemonophosphatesAnthranilate PhosphoribosyltransferaseHypoxanthinesPurine NucleotidesApazoneAmidophosphoribosyltransferasePhosphotransferasesNucleotidesDiphosphatesCarcinoma, Ehrlich TumorHypoxanthine PhosphoribosyltransferasePentosyltransferasesCalcium PyrophosphateThiamine PyrophosphateOrotate PhosphoribosyltransferaseTechnetium Tc 99m PyrophosphatePolyisoprenyl PhosphatesLesch-Nyhan SyndromeATP PhosphoribosyltransferaseAdenine Phosphoribosyltransferaseortho-AminobenzoatesNicotinamide MononucleotidePhosphoric AcidsChondrocalcinosisDimethylallyltranstransferaseInosine MonophosphatePyrophosphatasesThiamineTransferases
Phosphoribosyl pyrophosphate - WikipediaPhosphoribosyl pyrophosphate - Wikipedia
Phosphoribosyl pyrophosphate (PRPP) is a pentose phosphate. It is a biochemical intermediate in the formation of purine ... Decreased levels of hypoxanthine guanine phosphoribosyl transferase (HGPRT) causes this accumulation, as PRPP is a substrate ... "Crystal structure of human phosphoribosylpyrophosphate synthetase 1 reveals a novel allosteric site". Biochemical Journal. 401 ...
https://en.wikipedia.org/wiki/Phosphoribosyl_pyrophosphate
Prps1l3 phosphoribosyl pyrophosphate synthetase 1-like 3 [Mus musculus (house mouse)] - Gene - NCBIPrps1l3 phosphoribosyl pyrophosphate synthetase 1-like 3 [Mus musculus (house mouse)] - Gene - NCBI
Prps1l3 phosphoribosyl pyrophosphate synthetase 1-like 3 [Mus musculus] Prps1l3 phosphoribosyl pyrophosphate synthetase 1-like ... phosphoribosyl pyrophosphate synthetase 1-like 3provided by MGI. Primary source. MGI:MGI:3779453 See related. Ensembl: ... Prps1l3 phosphoribosyl pyrophosphate synthetase 1-like 3 [ Mus musculus (house mouse) ] Gene ID: 328099, updated on 7-Sep-2023 ... Orthologous to human PRPS1 (phosphoribosyl pyrophosphate synthetase 1). [provided by Alliance of Genome Resources, Apr 2022]. ...
https://www.ncbi.nlm.nih.gov/gene/?term=328099
PRPS1 gene: MedlinePlus GeneticsPRPS1 gene: MedlinePlus Genetics
The PRPS1 gene provides instructions for making an enzyme called phosphoribosyl pyrophosphate synthetase 1, or PRPP synthetase ... The PRPS1 gene provides instructions for making an enzyme called phosphoribosyl pyrophosphate synthetase 1, or PRPP synthetase ... Mutations in PRPS1, which encodes the phosphoribosyl pyrophosphate synthetase enzyme critical for nucleotide biosynthesis, ... This enzyme helps produce a molecule called phosphoribosyl pyrophosphate (PRPP). PRPP is involved in making purine and ...
https://medlineplus.gov/genetics/gene/prps1/
Collection of regulogs controlled by 5-phosphoribosyl 1-pyrophosphateCollection of regulogs controlled by 5-phosphoribosyl 1-pyrophosphate
Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes ...
https://regprecise.lbl.gov/collection_effector.jsp?effector_id=209
PRPS1, PRPS2, PRPS3, NT (Ribose-phosphate pyrophosphokinase 1, PPRibP, Phosphoribosyl pyrophosphate synthase I) | Technique...
Suppliers / MyBioSource / PRPS1, PRPS2, PRPS3, NT (Ribose-phosphate pyrophosphokinase 1, PPRibP, Phosphoribosyl pyrophosphate ... PRPS1, PRPS2, PRPS3, NT (Ribose-phosphate pyrophosphokinase 1, PPRibP, Phosphoribosyl pyrophosphate synthase I). ...
http://phosphokinase.com/top-products-list/2102-mybiosource/3396-prps1-prps2-prps3-nt-ribose-phosphate-pyrophosphokinase-1-ppribp-phosphoribosyl-pyrophosphate-syntha
Simpler method for the determination of 5-phosphoribosyl-1-pyrophosphate in red blood cells<...Simpler method for the determination of 5-phosphoribosyl-1-pyrophosphate in red blood cells<...
Sperling O, Eilam G, Persky-Brosh S, De Vries A. Simpler method for the determination of 5-phosphoribosyl-1-pyrophosphate in ... Simpler method for the determination of 5-phosphoribosyl-1-pyrophosphate in red blood cells. / Sperling, Oded; Eilam, Gavriela ... Simpler method for the determination of 5-phosphoribosyl-1-pyrophosphate in red blood cells. In: Translational Research. 1972 ... Dive into the research topics of Simpler method for the determination of 5-phosphoribosyl-1-pyrophosphate in red blood cells ...
https://cris.tau.ac.il/en/publications/simpler-method-for-the-determination-of-5-phosphoribosyl-1-pyroph
CATH Superfamily 3.40.50.2020CATH Superfamily 3.40.50.2020
FunFam 138: Phosphoribosyl pyrophosphate synthase-associated p.... * Summary * Alignment * GO * EC * Taxonomy ...
http://www.cathdb.info/version/v4_3_0/superfamily/3.40.50.2020/funfam/138/go
Genetics of kidney stone disease | Nature Reviews UrologyGenetics of kidney stone disease | Nature Reviews Urology
... reduced affinity for 5-phosphoribosyl-1-pyrophosphate manifested only at low, physiological substrate concentrations. Biochim. ... Phosphoribosylpyrophosphate and purine metabolism in cultured fibroblasts. J. Clin. Invest. 56, 1093-1099 (1975). ... Human X-linked phosphoribosylpyrophosphate synthetase superactivity is associated with distinct point mutations in the PRPS1 ... Becker, M. A., Raivio, K. O., Bakay, B., Adams, W. B. & Nyhan, W. L. Variant human phosphoribosylpyrophosphate synthetase ...
https://www.nature.com/articles/s41585-020-0332-x?error=cookies_not_supported&code=68874d00-fdf3-4709-8253-9fbb269b25e3
Regulation of de novo purine synthesis in chick liver slices. Role of phosphoribosylpyrophosphate availability and of salvage...Regulation of de novo purine synthesis in chick liver slices. Role of phosphoribosylpyrophosphate availability and of salvage...
... a high content and availability of 5-phosphoribosyl 1-pyrophosphate (PP-rib-P), comparable activity of PP-rib-P synthetase, and ... a high content and availability of 5-phosphoribosyl 1-pyrophosphate (PP-rib-P), comparable activity of PP-rib-P synthetase, and ... a high content and availability of 5-phosphoribosyl 1-pyrophosphate (PP-rib-P), comparable activity of PP-rib-P synthetase, and ... a high content and availability of 5-phosphoribosyl 1-pyrophosphate (PP-rib-P), comparable activity of PP-rib-P synthetase, and ...
https://cris.tau.ac.il/en/publications/regulation-of-de-novo-purine-synthesis-in-chick-liver-slices-role
Human Genome Variation Society
phosphoribosyl pyrophosphate synthetase 1 311850 PRPS1 database at LOVD Johan T. den Dunnen Leiden Univ. Med Centre (acting), ... phosphoribosyl pyrophosphate synthetase 2 311860 PRPS2 database at LOVD Johan T. den Dunnen Leiden Univ. Med Centre (acting), ...
http://www.hgvs.org/locus-specific-mutation-databases/p?field_hgnc_gene_symbol_title=
metabolic pathway pertinent to the brain - Ontology Report - Rat Genome Databasemetabolic pathway pertinent to the brain - Ontology Report - Rat Genome Database
phosphoribosyl pyrophosphate amidotransferase. ISO. SMPDB. SMP:00072. NCBI chr14:31,215,741...31,250,144 Ensembl chr14: ...
https://rgd.mcw.edu/rgdweb/ontology/annot.html?acc_id=PW:0000406
Brain tissue expression of NECAB1 - Summary - The Human Protein AtlasBrain tissue expression of NECAB1 - Summary - The Human Protein Atlas
Phosphoribosyl pyrophosphate synthetase 2. 0.8351. 40. LY6D. Lymphocyte antigen 6 family member D. 0.8351. 53. ...
https://www.proteinatlas.org/ENSG00000123119-NECAB1/brain
Human Metabolome Database: Showing metabocard for 6-Methylmercaptopurine (HMDB0060412)Human Metabolome Database: Showing metabocard for 6-Methylmercaptopurine (HMDB0060412)
6-Methylmercaptopurine + Phosphoribosyl pyrophosphate → 6-Methylthiopurine 5-monophosphate ribonucleotide + Pyrophosphate. ... Transfers the 5-phosphoribosyl group from 5-phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation ...
https://hmdb.ca/metabolites/HMDB0060412
Student and Faculty Work | Middlebury CollegeStudent and Faculty Work | Middlebury College
2000) "The Formation of a 1-5 Phosphodiester Linkage in the Spontaneous Breakdown of 5-Phosphoribosyl-a-1-Pyrophosphate", J. ... "The Catalytic Effect of Mg2+ and Imidazole on the Decomposition of 5-Phosphoribosyl-a-1-pyrophosphate in Aqueous Solution" (in ...
https://www.middlebury.edu/college/academics/molecular-biology-biochemistry/student-and-faculty-work
Charcot-Marie-Tooth Disease Neuropathies: An Introduction: Overview, Clinical Presentation, Diagnostic ConsiderationsCharcot-Marie-Tooth Disease Neuropathies: An Introduction: Overview, Clinical Presentation, Diagnostic Considerations
Mutations in PRPS1, which encodes the phosphoribosyl pyrophosphate synthetase enzyme critical for nucleotide biosynthesis, ...
https://www.medscape.com/answers/1173484-176761/which-lifestyle-modifications-are-used-the-treatment-of-charcot-marie-tooth-cmt-disease
Ligand view of caffeine (7965 - RYYVLZVUVIJVGH-UHFFFAOYSA-N) - BRENDA Enzyme DatabaseLigand view of caffeine (7965 - RYYVLZVUVIJVGH-UHFFFAOYSA-N) - BRENDA Enzyme Database
Modulation of glycogen phosphorylase activity affects 5-phosphoribosyl-1-pyrophosphate availability in rat hepatocyte cultures ...
https://www.brenda-enzymes.org/ligand.php?brenda_ligand_id=7965
Michael Johnson | Department of ChemistryMichael Johnson | Department of Chemistry
... cluster which inhibits inositol pyrophosphate 1-phosphatase activity. Biochemistry 2015, 54, 6462-74. ... Spectroscopic characterization of the iron-sulfur cluster in Bacillus subtilis glutamine phosphoribosylpyrophosphate ...
https://www.chem.uga.edu/directory/people/michael-johnson
Intermediate CMT - Types of Charcot-Marie-Tooth Disease (CMT) - Diseases | Muscular Dystrophy AssociationIntermediate CMT - Types of Charcot-Marie-Tooth Disease (CMT) - Diseases | Muscular Dystrophy Association
Kim, H.-J. et al. Mutations in PRPS1, Which Encodes the Phosphoribosyl Pyrophosphate Synthetase Enzyme Critical for Nucleotide ...
https://www.mda.org/disease/charcot-marie-tooth/types/cmt-intermediate
Mizoribine: A New Approach in the Treatment of Renal DiseaseMizoribine: A New Approach in the Treatment of Renal Disease
In the de novo pathway, the ribose phosphate portion of purine nucleotides is derived from 5-phosphoribosyl 1-pyrophosphate ( ...
https://www.hindawi.com/journals/jir/2009/681482/
Frontiers | KSHV Reprogramming of Host Energy Metabolism for PathogenesisFrontiers | KSHV Reprogramming of Host Energy Metabolism for Pathogenesis
... including phosphoribosyl pyrophosphate aminotransferase (PPAT), phosphoribosyl pyrophosphate synthetases 1 and 2 (PRPS1/2), or ...
https://www.frontiersin.org/articles/10.3389/fcimb.2021.621156/full
Enzyme families | IUPHAR/BPS Guide to PHARMACOLOGYEnzyme families | IUPHAR/BPS Guide to PHARMACOLOGY
C44: Phosphoribosyl pyrophosphate amidotransferase. *T1: Proteasome C. *T2: Glycosylasparaginase precursor. *PC: Cysteine (C) ...
https://www.guidetopharmacology.org/GRAC/ReceptorFamiliesForward
Glucagon-Like Peptide 1 Inhibits the Sirtuin Deacetylase SirT1 to Stimulate Pancreatic β-Cell Mass Expansion | Diabetes |...
5-phosphoribosyl-1-pyrophosphate, and [14C]nicotinamide for 30 min; filtered through glass fiber filters; and washed with ...
https://diabetesjournals.org/diabetes/article/60/12/3217/14289/Glucagon-Like-Peptide-1-Inhibits-the-Sirtuin
CoP: Co-expressed Biological Processes
ATASE1 (GLN PHOSPHORIBOSYL PYROPHOSPHATE AMIDOTRANSFERASE 1). Amidophosphoribosyltransferase (ATase: EC 2.4.2.14) is a key ...
http://webs2.kazusa.or.jp/kagiana/cgi-bin/xp2g.cgi?gsm=E-ATMX-13-raw-cel-1556149823&organism=ath
CoP: Co-expressed Biological Processes
ATASE1 (GLN PHOSPHORIBOSYL PYROPHOSPHATE AMIDOTRANSFERASE 1). Amidophosphoribosyltransferase (ATase: EC 2.4.2.14) is a key ...
http://webs2.kazusa.or.jp/kagiana/cgi-bin/xp2g.cgi?gsm=E-MEXP-1797-raw-cel-1669768030&organism=ath
GSE12392 WT VS IFNB KO CD8A NEG SPLEEN DC DNGSE12392 WT VS IFNB KO CD8A NEG SPLEEN DC DN
phosphoribosyl pyrophosphate synthetase .... PTK2. 5747. PTK2. protein tyrosine kinase 2 [Source:HGNC S.... ...
https://www.gsea-msigdb.org/gsea/msigdb/geneset_page.jsp?geneSetName=GSE12392_WT_VS_IFNB_KO_CD8A_NEG_SPLEEN_DC_DN
NamespaceNamespace
O Elevated urine pyrophosphate,O Elevated vascular endothelial growth factor level,O Elfin facies,O Elliptocytosis,O Elongated ... O Increased phosphoribosylpyrophosphate synthetase 1 activity,O Increased pineal volume,O Increased pitch variability of speech ... O Elevated plasma pyrophosphate,O Elevated propionylcarnitine level,O Elevated proportion of CD4-negative, CD8-negative, alpha- ...
https://raw.githubusercontent.com/pharmacome/terminology/c328ad964c08967a0417a887510b97b965a62fa5/external/hp-names.belns
生命科學專業學院 - 研究成果 - 國立臺生命科學專業學院 - 研究成果 - 國立臺
Characterization of Arabidopsis glutamine phosphoribosyl pyrophosphate amidotransferase-deficient mutants. Hung, W. F., Chen, L ...
https://scholar.lib.ntnu.edu.tw/zh/organisations/school-of-life-science/publications/?ordering=publicationYearThenTitle&descending=true&page=25
6 mercaptopurine. Medical search6 mercaptopurine. Medical search
Phosphoribosyl Pyrophosphate. The key substance in the biosynthesis of histidine, tryptophan, and purine and pyrimidine ... An enzyme that catalyzes the conversion of 5-phosphoribosyl-1-pyrophosphate and hypoxanthine, guanine, or 6-mercaptopurine to ... AgentsAsparaginaseGuanine NucleotidesThioinosinePurinesInosine MonophosphatePharmacologyPhosphoribosyl Pyrophosphate ... Immunosuppressive AgentsAsparaginaseGuanine NucleotidesThioinosinePurinesInosine MonophosphatePhosphoribosyl Pyrophosphate ...
https://lookformedical.com/en/search/6-mercaptopurine
Antiretroviral Agents and Treatment of HIV Infection | Goodman & Gilmans: The Pharmacological Basis of Therapeutics, 14th...Antiretroviral Agents and Treatment of HIV Infection | Goodman & Gilman's: The Pharmacological Basis of Therapeutics, 14th...
PRPP: phosphoribosyl pyrophosphate. QTc: corrected cardiac QT interval. RNase H: ribonuclease H ...
https://hemonc.mhmedical.com/content.aspx?bookid=3191§ionid=267906247
PathBankPathBank
Phosphoribosyl. pyrophosphate. Pyrophosphate. Adenosine. monophosphate. Water. D-Ribose. 5-phosphate. Adenine. nupG. nupC. ribC ... Phosphoribosyl. pyrophosphate. PP. i. Adenosine. monophosphate. H. 2. O. D-Ribose. 5-phosphate. Adenine. Magnesium. Periplasm. ... The adenine then reacts with a PRPP through a adenine phosphoribosyltransferase resulting in the release of a pyrophosphate and ...
https://pathbank.org/view/SMP0002084