PLTP - Phospholipid transfer protein precursor - Homo sapiens (Human) - PLTP gene & protein
Two distinct forms of PLTP exist in plasma: an active form that can transfer PC from phospholipid vesicles to high-density ... Essential for the transfer of excess surface lipids from triglyceride-rich lipoproteins to HDL, thereby facilitating the ... Facilitates the transfer of a spectrum of different lipid molecules, including diacylglycerol, phosphatidic acid, sphingomyelin ... Phospholipid transfer proteinAdd BLAST. 476. Amino acid modifications. Feature key. Position(s). DescriptionActions. Graphical ...http://www.uniprot.org/uniprot/P55058
Identification and Characterization of Dual Inhibitors for Phospholipid Transfer Protein and Microsomal Triglyceride Transfer...
phospholipid transfer protein. CETP. cholesteryl ester transfer protein. LDL. low-density lipoprotein. MTP. microsomal ... 1985) Plasma phospholipid transfer protein enhances transfer and exchange of phospholipids between very low density ... 2005) Transfer of cholesteryl esters and phospholipids as well as net deposition by microsomal triglyceride transfer protein. J ... 2006) Phospholipid transfer activity of microsomal triacylglycerol transfer protein is sufficient for the assembly and ...http://jpet.aspetjournals.org/content/335/3/653.long
Abstract 127: Structure and Function Relationship of Phospholipid Transfer Protein in Lipid Transfer Activity Revealed by...
Human phospholipid transfer protein (PLTP) mediates the transfer of lipids among atheroprotective high-density lipoproteins ( ... Abstract 127: Structure and Function Relationship of Phospholipid Transfer Protein in Lipid Transfer Activity Revealed by ... Abstract 127: Structure and Function Relationship of Phospholipid Transfer Protein in Lipid Transfer Activity Revealed by ... Abstract 127: Structure and Function Relationship of Phospholipid Transfer Protein in Lipid Transfer Activity Revealed by ...http://circres.ahajournals.org/content/117/Suppl_1/A127
Amino acid sequence of a non-specific wheat phospholipid transfer protein and its conformation as revealed by infrared and...
Finally, the wheat phospholipid transfer protein has no effect on the thermotropic behavior of large unilamellar vesicles of ... the results obtained show that plant non specific phospholipid transfer proteins are not almost entirely composed of beta- ... infrared spectroscopy and this is the first report on the structure of non specific plant phospholipid transfer proteins. As ... No major conformational changes of the protein are observed when it is adsorbed to phospholipid vesicles. These results suggest ...https://www.semanticscholar.org/paper/Amino-acid-sequence-of-a-non-specific-wheat-phosph-Desormeaux-Blochet/26db033c4c163d7e381693602dd08f25319d07f1
Targeting Cholesteryl Ester Transfer Protein for the Prevention and Management of Cardiovascular Disease | JACC: Journal of the...
... lipoproteins contain a core of mainly CEs and a small amount of triglycerides surrounded by surface of phospholipids, free ... Role of cholesteryl ester transfer protein (CETP) in plasma lipid transport. Cholesteryl ester transfer protein promotes ... Effect of cholesteryl ester transfer protein (CETP) on lipoprotein particle size. Cholesteryl ester transfer protein mediates ... Cholesteryl ester transfer protein (CETP) transfers cholesteryl esters from high-density lipoproteins (HDL) to very low-density ...http://www.onlinejacc.org/content/47/3/492
Proteolytic activation of bovine brain protein with phosphatidylinositol transfer activity
... higher affinity for this phospholipid. The possibility that the 38 kDa protein is a precursor of the phosphatidylinositol ... 35 kDa phosphatidylino-sitol transfer protein from the same source. Controlled trypsinization of the 38 kDa protein yielded an ... Proteolytic activation of bovine brain protein with phosphatidylinositol transfer activity. Journal. FEBS Letters. Volume. 276 ... transfer protein is discussed.(C) 1990 Elsevier Science B.V. All rights reserved. ...http://dare.uva.nl/search?metis.record.id=426218
Identification and assessment of the role of a nominal phospholipid binding region of ORP1S (oxysterol-binding-protein-related...
... of Golgi-derived vesicular transport mediated by the essential phosphatidylinositol/phosphatidylcholine transfer protein Sec14p ... oxysterol-binding-protein-related protein; ORP1L, ORP1 long; ORP1S, ORP1 short; OSBP, oxysterol binding protein; PC, ... Identification and assessment of the role of a nominal phospholipid binding region of ORP1S (oxysterol-binding-protein-related ... Identification and assessment of the role of a nominal phospholipid binding region of ORP1S (oxysterol-binding-protein-related ...http://www.biochemj.org/content/387/3/889
Phospholipid transfer protein - Wikipedia
Phospholipid transfer protein is a protein that in humans is encoded by the PLTP gene. The protein encoded by this gene is one ... "Evaluation of phospholipid transfer protein and cholesteryl ester transfer protein as contributors to the generation of pre ... "Concerted actions of cholesteryl ester transfer protein and phospholipid transfer protein in type 2 diabetes: effects of ... of at least two lipid transfer proteins found in human plasma. The encoded protein transfers phospholipids from triglyceride- ...https://en.wikipedia.org/wiki/Phospholipid_transfer_protein
Human Metabolome Database: Showing Protein Phospholipid transfer protein (HMDBP02549)
Showing Protein Phospholipid transfer protein (HMDBP02549). IdentificationBiological propertiesGene propertiesProtein ... Qu SJ, Fan HZ, Kilinc C, Pownall HJ: Role of cysteine residues in human plasma phospholipid transfer protein. J Protein Chem. ... Complete cDNA encoding human phospholipid transfer protein from human endothelial cells. J Biol Chem. 1994 Mar 25;269(12):9388- ... May play a key role in extracellular phospholipid transport and modulation of hdl particles. ...http://www.hmdb.ca/proteins/HMDBP02549
pltp, phospholipid transfer protein - Creative Biogene
PLTP; phospholipid transfer protein; BPI fold containing family E; BPIFE; lipid transfer protein II; HDLCQ9; zgc:100903 ... The protein encoded by this gene is one of at least two lipid transfer proteins found in human plasma. The encoded protein ... transfers phospholipids from triglyceride-rich lipoproteins to high density lipoprotein (HDL). In addition to regulating the ... Creative Biogene Introduces Innovative Expression Vectors for High Level of Protein Production ...https://www.creative-biogene.com/symbolsearch_pltp.html
Macrophage Phospholipid Transfer Protein Deficiency and ApoE Secretion | Arteriosclerosis, Thrombosis, and Vascular Biology
Distribution of phospholipid transfer protein in human plasma: presence of two forms of phospholipid transfer protein, one ... and phospholipid in mice expressing the human phospholipid transfer protein and human apolipoprotein AI transgenes. J Clin ... Active plasma phospholipid transfer protein is associated withApo AI- but not Apo E-containing lipoproteins. J Lipid Res. 2006 ... High plasma phospholipid transfer protein levels as a risk factor for coronary artery disease. Arterioscler Thromb Vasc Biol. ...http://atvb.ahajournals.org/content/27/1/190
IDEALS @ Illinois: Roles of human plasma phospholipid transfer protein in high-density lipoprotein metabolism
Roles of human plasma phospholipid transfer protein in high-density lipoprotein metabolism. Welcome to the IDEALS Repository. ... A simple method for the purification of phospholipid transfer protein (PLTP) from human plasma was developed. Molecular weight ... Roles of human plasma phospholipid transfer protein in high-density lipoprotein metabolism. Tu, An-Yue ... Roles of human plasma phospholipid transfer protein in high-density lipoprotein metabolism. ...https://www.ideals.illinois.edu/handle/2142/23065
ApoE-containing high density lipoproteins and phospholipid transfer protein activity increase in patients with a systemic...
... whereas the role of phospholipid transfer protein (PLTP) and cholesteryl ester transfer protein has not been analyzed in detail ... ApoE-containing high density lipoproteins and phospholipid transfer protein activity increase in patients with a systemic ... We have studied the activities of HDL-modifying proteins and the heterogeneity of HDL in healthy control subjects and three ... In summary, the increase in apoE HDL and PLTP activity may improve the delivery of energy substrates and phospholipids to ...https://www.sigmaaldrich.com/catalog/papers/11181759
Phospholipid Transfer Protein Augments Apoptosis in THP-1-Derived Macrophages Induced by Lipolyzed Hypertriglyceridemic Plasma ...
Active and low-active forms of serum phospholipid transfer protein in a normal Finnish population sample
... Janis MT; Siggins S; ...http://www.julkari.fi/handle/10024/82865
Lysophosphatidylcholine Acyltransferase 1 (LPCAT1) Specifically Interacts with Phospholipid Transfer Protein StarD10 to...
Keywords: lipid-binding protein, lipid trafficking, phospholipid, protein expression, protein-protein interaction ... steroidogenic acute regulatory protein-related lipid transfer. StarD. START domain-containing protein. PCTP. PC transfer ... a START domain protein overexpressed in breast cancer, functions as a phospholipid transfer protein. J. Biol. Chem. 280, 27436- ... Specifically Interacts with Phospholipid Transfer Protein StarD10 to Facilitate Surfactant Phospholipid Trafficking in Alveolar ...http://pubmedcentralcanada.ca/pmcc/articles/PMC4513115/
Phospholipid Transfer Protein is Differentially Expressed in Human Arterial and Venous Placental Endothelial Cells and Enhances...
Phospholipid Transfer Protein is Differentially Expressed in Human Arterial and Venous Placental Endothelial Cells and Enhances ...http://www.julkari.fi/handle/10024/106830
Structural and functional determinants of human plasma phospholipid transfer protein activity as revealed by site-directed...
... exchanges phospholipids between lipoproteins and remodels high-density lipoproteins (HDLs). We determined phospholipid transfer ... The data support a model of transfer in which N- and C-terminal pockets have different roles in HDL binding and transfer ... A mutation in the C-terminal pocket (E270R) led to a decrease in both the specific transfer activity and the level of binding ... The N-terminal pocket may be critical to PLTP transfer activity but may have no involvement in binding to lipoproteins, whereas ...https://www.semanticscholar.org/paper/Structural-and-functional-determinants-of-human-as-Ponsin-Qu/fbceafe038961acad2f95a1e2fa85950bda547a0
Attenuation of atherogenic apo B-48-dependent hyperlipidemia and high density lipoprotein remodeling induced by vitamin C and E...
Phospholipid transfer protein activity. Lipid transfer assay for phospholipid transfer protein (PLTP) was performed in total ... c HDL phospholipids. d Apolipoprotein A-I abundance. e Phospholipid transfer protein (PLTP) activity. f PLTP abundance. ... This lower HDL phospholipid content was most likely due the diminished abundance and activity of phospholipid transfer protein ... Effect of vitamin C and E combination on HDL lipids and apo A-I and serum phospholipid transfer protein in SR-B1 KO/ApoER61h/h ...https://link.springer.com/article/10.1186%2Fs40659-018-0183-6
publications - sskimb
Crystallization and preliminary X-ray crystallographic analysis of phospholipid transfer protein from maize seedings. Dong Hae ... Prediction of protein-protein interaction types using association rule based classification. Sung Hee Park, Jose A Reyes, David ... Adenovirus-mediated transfer of siRNA against PTTG1 inhibits liver cancer cell growth in vitro and in vivo Cho-Rok J, Yoo J, ... Euclidean Voronoi Diagrams of 3D Spheres and Applications to Protein Structure Analysis D-S. Kim, Y. Cho, D. Kim, S. Kim, J. ...https://sites.google.com/site/sskimb/publications
Recessive mutations in ATP8A2 cause severe hypotonia, cognitive impairment, hyperkinetic movement disorders and progressive...
ATP8A2; Chorea; Choreoathetosis; Developmental disabilities; Dystonia; Optic atrophy; Phospholipid transfer protein; Whole ... c Quantification of ATP8A2 protein expression from western blots expressed as an average +/-SEM for n = 4. P values ** are ≤ ...https://www.ncbi.nlm.nih.gov/pubmed/30012219
4D and F). Phospholipid transfer protein (PLTP) promotes VLDL secretion by transferring phospholipids onto VLDL particles (35 ... Elevation of plasma phospholipid transfer protein in transgenic mice increases VLDL secretion. J Lipid Res 2002;43:1875-1880 ... Estrogen treatment blocks the effects of hyperinsulinemia to reduce hepatic apoB100 and phospholipid transfer protein.. To ... Microsomal triglyceride transfer protein expression in adipocytes: a new component in fat metabolism. FEBS Lett 2005;579:3183- ...http://diabetes.diabetesjournals.org/content/62/2/424
Plasma lipases and lipid transfer proteins increase phospholipid but not free cholesterol transfer from lipid emulsion to high...
... study of phospholipid transfer activities mediated by cholesteryl ester transfer protein and phospholipid transfer protein. J ... It is concluded that: 1-intravascular lipases stimulate phospholipid transfer protein mediated phospholipid transfer, but not ... Plasma phospholipid transfer protein enhances transfer and exchange of phospholipids between VLDL and HDL lipoproteins during ... Plasma lipases and lipid transfer proteins increase phospholipid but not free cholesterol transfer from lipid emulsion to high ...https://bmcbiochem.biomedcentral.com/articles/10.1186/1471-2091-2-1
Anti-PLTP antibody (ab85562) | Abcam
Lipid transfer protein II antibody. *OD107 antibody. *Phospholipid transfer protein antibody. *Plasma phospholipid transfer ... Proteins and Peptides. Proteomics tools. Agonists, activators, antagonists and inhibitors. Lysates. Multiplex miRNA assays. By ... The Universal Protein Resource (UniProt) in 2010. Nucleic Acids Res. 38:D142-D148 (2010) . ... May play a key role in extracellular phospholipid transport and modulation of hdl particles. ...http://www.abcam.com/pltp-antibody-ab85562.html
27 High definition lipoproteomics reveal dysregulated redox proteins in coronary artery disease | Heart
Phospholipid transfer protein (PLTP) (p , 0.001) and apolipoprotein (a) (p = 0.002) were over expressed in the CAD patients. ... Results 202 proteins showed significant differential expression between the CAD patients and the control subjects (P , 0.05). ... Furthermore, there was selective up-regulation of proteins concerned with inflammation; serum amyloid A-1 (p , 1e-12), mannan ... The measurement of certain lipoprotein associated proteins may assist in the early identification of such patients before ...http://heart.bmj.com/content/101/Suppl_6/A9.1