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*  Inhibition of 3-Phosphoglycerate Dehydrogenase from Pisum sativum by Pyridoxal 5′-Phosphate and by Pyridoxamine 5′-Phosphate |...
Inhibition of 3-Phosphoglycerate Dehydrogenase from Pisum sativum by Pyridoxal 5′-Phosphate and by Pyridoxamine 5′-Phosphate. J ... Inhibition of 3-Phosphoglycerate Dehydrogenase from Pisum sativum by Pyridoxal 5′-Phosphate and by Pyridoxamine 5′-Phosphate ... Inhibition of 3-Phosphoglycerate Dehydrogenase from Pisum sativum by Pyridoxal 5′-Phosphate and by Pyridoxamine 5′-Phosphate ... Inhibition of 3-Phosphoglycerate Dehydrogenase from Pisum sativum by Pyridoxal 5′-Phosphate and by Pyridoxamine 5′-Phosphate ...
http://www.biochemsoctrans.org/content/3/6/1058.2
*  Mouse Genetics Suggests Cell-Context Dependency for Myc-Regulated Metabolic Enzymes during Tumorigenesis
3-Phosphoglycerate dehydrogenase (Phgdh) and Serine hydroxymethyltransferase 1 (Shmt1), we obtained offspring that were ... 3-phosphoglycerate dehydrogenase (Phgdh); Serine hydroxymethyltransferase (SHMT) 1 and 2; and Pim-3 (a member of the Pim family ... In this dissertation, I have focused on several Myc target genes, Spermidine synthase (Srm); Lactate dehydrogenase (Ldh); ... cancer, Myc, metabolism, polyamines, spermidine synthase, glycolysis, lactate dehydrogenase, serine metabolism, Phgdh, folate ...
http://www.diva-portal.org/smash/record.jsf?pid=diva2:438875
*  The importance of serine metabolism in cancer | JCB
isocitrate dehydrogenase. MTHFD. methylenetetrahydrofolate dehydrogenase. PEP. phosphoenolpyruvate. PHGDH. phosphoglycerate ... Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis. Nat. Genet. 43:869-874. doi:10.1038/ng. ... Human phosphoglycerate dehydrogenase produces the oncometabolite D-2-hydroxyglutarate. ACS Chem. Biol. 10:510-516. doi:10.1021/ ... Phosphoglycerate dehydrogenase is dispensable for breast tumor maintenance and growth. Oncotarget. 4:2502-2511. doi:10.18632/ ...
http://jcb.rupress.org/content/214/3/249?cct=1418
*  anti-PHGDH antibody [N3C2], Internal | GeneTex
... phosphoglycerate dehydrogenase) for IHC-Fr, IHC-P, WB. Anti-PHGDH pAb (GTX101949) is tested in Human, Rat samples. 100% Ab- ... 3-phosphoglycerate dehydrogenase antibody, D-3-phosphoglycerate dehydrogenase antibody, phosphoglycerate dehydrogenase antibody ... phosphoglycerate dehydrogenase. Background. 3-Phosphoglycerate dehydrogenase (PHGDH; EC 1.1.1.95) catalyzes the transition of 3 ... phosphoglycerate into 3-phosphohydroxypyruvate, which is the first and rate-limiting step in the phosphorylated pathway of ...
http://www.genetex.com/PHGDH-antibody-N3C2-Internal-GTX101949.html
*  Browsing by Subject "D-serine"
3-phosphoglycerate dehydrogenase .... * The Novel Role of D-serine in Synaptic Transmission and Psychiatric Disorders  Ma, ...
https://jscholarship.library.jhu.edu/browse?value=D-serine&type=subject
*  Phgdh elisa kit product blog
Mouse D-3-phosphoglycerate dehydrogenase, PHGDH ELISA Kit. (Or you can also download the PDF Manual for complete product ... Mouse D-3-phosphoglycerate dehydrogenase, PHGDH ELISA Kit or ELISA (enzyme-linked immunosorbant assays) Kits in general, are a ... Tags: ELISA Kit; Mouse ELISA Kit; PHGDH; phosphoglycerate dehydrogenase; PHGDH elisa kit; ... PHOSPHOGLYCERATE DEHYDROGENASE DEFICIENCY, Seizures, Skin Diseases are some of the diseases may be linked to Mouse D-3- ...
http://blog.mybiosource.com/phgdh-elisa-kit_2602994
*  Neu-Laxova syndrome NGS panel | Connective Tissue Gene Tests
Phosphoglycerate dehydrogenase deficiency (PHGDHD; MIM 601815) and phosphoserine aminotransferase deficiency (PSATD; MIM 610992 ... They code for D-3-phosphoglycerate dehydrogenase and phosphoserine aminotransferase enzymes, respectively. These enzymes are ...
http://ctgt.net/panel/neu-laxova-syndrome-ngs-panel
*  Engineering of Serine-Deamination pathway, Entner-Doudoroff pathway and pyruvate dehydrogenase complex to improve poly(3...
L-serine is synthesized from D-3-phosphoglycerate by three reactions catalyzed by D-3-phosphoglycerate dehydrogenase, D-3- ... phosphoglycerate kinase; SerA, D-3-phosphoglycerate dehydrogenase; SerB, phosphoserine phosphatase; SerC, 3-phosphoserine ... Moreover, a published report has showed that a truncated D-3-phosphoglycerate dehydrogenase (PGDH) serA Δ197 was no longer ... Peters-Wendisch P, Netzer R, Eggeling L, Sahm H: 3-Phosphoglycerate dehydrogenase from Corynebacterium glutamicum : the C- ...
https://microbialcellfactories.biomedcentral.com/articles/10.1186/s12934-014-0172-6
*  1H, 15N, 13C backbone resonance assignments of human phosphoglycerate kinase in a transition state analogue complex with ADP, 3...
Modulation of DNA polymerases alpha, delta and epsilon by lactate dehydrogenase and 3-phosphoglycerate kinase. Biochim Biophys ... Phosphoglycerate kinase acts in tumour angiogenesis as a disulphide reductase. Nature. 2000;408:869-873. doi: 10.1038/35048596. ... Human phosphoglycerate kinase (PGK) is an energy generating glycolytic enzyme that catalyses the transfer of a phosphoryl group ... Phosphoglycerate kinase (PGK, EC 2.7.2.3) is a bisubstrate magnesium-dependent enzyme with highly conserved amino acid ...
http://pubmedcentralcanada.ca/pmcc/articles/PMC5594045/
*  Phosphoglycerate Kinase 2 (PGK2) (AA 1-417) (Active) protein (His tag)</span...
Recombinant Phosphoglycerate Kinase 2 (PGK2) Protein (His tag). Species: Human. Source: Escherichia coli (E. coli). Order ... Phosphoglycerate Kinase 1 Proteins * phosphoglycerate Dehydrogenase Proteins * Phosphogluconate Dehydrogenase Proteins * ... Phosphoglycerate Kinase 2 (PGK2) (AA 1-417) (Active) protein (His tag) Phosphoglycerate Kinase 2 (PGK2) (AA 1-417) (Active) ... Phosphoglycerate Kinase 2 (PGK2) (AA 1-417) (Active) protein (His tag) Phosphoglycerate Kinase 2 (PGK2) (AA 1-417) (Active) ...
http://www.antibodies-online.com/protein/1981682/Phosphoglycerate+Kinase+2+PGK2+AA+1-417+Active+protein+His+tag/
*  Glycolysis Made Easy | BioChemWiz - Nari R.
... aldolase triose phosphate isomerase glyceraldehyde-3-phosphate dehydrogenase phosphoglycerate kinase phosphoglycerate mutase ... glyceraldehyde-3-phosphate dehydrogenase. *phosphoglycerate kinase. *phosphoglycerate mutase. *enolase. *pyruvate kinase. Done. ...
https://naribiochemwiz007.wordpress.com/2013/04/13/glycolysis-made-easy-2/
*  August | 2017 | Discovery of potent and selective covalent inhibitors of JNK
... most likely triggered by reduced tethering of NFE2L2 to mitochondrial phosphoglycerate mutase 5. Age indirectly affected ... 11??-Hydroxysteroid Dehydrogenase *7-Transmembrane Receptors *Acetylcholine Nicotinic Receptors *Adrenergic ??1 Receptors ...
http://solventcentral.com/2017/08/
*  Phosphoglycerate Dehydrogenase: Potential Therapeutic Target and Putative Metabolic Oncogene
Cheryl K. Zogg, "Phosphoglycerate Dehydrogenase: Potential Therapeutic Target and Putative Metabolic Oncogene," Journal of ... Phosphoglycerate Dehydrogenase: Potential Therapeutic Target and Putative Metabolic Oncogene. Cheryl K. Zogg1,2 ...
https://www.hindawi.com/journals/jo/2014/524101/cta/
*  Phosphoglycerate Dehydrogenase: Potential Therapeutic Target and Putative Metabolic Oncogene
Shown in red, phosphoglycerate dehydrogenase, the first enzyme branching from glycolysis in a three-step serine biosynthetic ... 4. Reemergence of Phosphoglycerate Dehydrogenase: Breast Cancer. Studies of human PHGDH began to appear in subsequent years, ... J. Chen, F. Chung, G. G. Yang et al., "Phosphoglycerate dehydrogenase is dispensable for breast tumor maintenance and growth," ... Phosphoglycerate Dehydrogenase: Potential Therapeutic Target and Putative Metabolic Oncogene. Cheryl K. Zogg1,2 ...
https://www.hindawi.com/journals/jo/2014/524101/
*  Phosphoglycerate dehydrogenase - Wikipedia
3-Phosphoglycerate dehydrogenase catalyzes the transition of 3-phosphoglycerate into 3-phosphohydroxypyruvate, which is the ... heterozygous mutations in 3-phosphoglycerate dehydrogenase cause Neu-Laxova syndrome and phosphoglycerate dehydrogenase ... 3-phosphoglycerate dehydrogenase works via an induced fit mechanism to catalyze the transfer of a hydride from the substrate to ... 3-Phosphoglycerate dehydrogenase is a tetramer, composed of four identical, asymmetric subunits. At any time, only a maximum of ...
https://en.wikipedia.org/wiki/Phosphoglycerate_dehydrogenase
*  SER33 - D-3-phosphoglycerate dehydrogenase 2 - Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) - SER33...
D-3-phosphoglycerate dehydrogenase 2 (SER33), D-3-phosphoglycerate dehydrogenase 1 (SER3) ... D-3-phosphoglycerate dehydrogenase 2Add BLAST. 468. Amino acid modifications. Feature key. Position(s). DescriptionActions. ... phosphoglycerate dehydrogenase activity Source: SGD ,p>Inferred from Mutant Phenotype,/p> ,p>Describes annotations that are ... sp,P40510,SER33_YEAST D-3-phosphoglycerate dehydrogenase 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 ...
https://www.uniprot.org/uniprot/P40510
*  PHGDH recombinant protein | D-3-phosphoglycerate dehydrogenase (PHGDH) Recombinant Protein-NP 006614.2
D-3-phosphoglycerate dehydrogenase (PHGDH) Recombinant Protein-NP_006614.2 (MBS1174268) product datasheet at MyBioSource, ... Phosphoglycerate Dehydrogenase Deficiency Antibodies. >3 publications with PHGDH and Phosphoglycerate Dehydrogenase Deficiency ...
https://www.mybiosource.com/phgdh-recombinant-protein/d-3-phosphoglycerate-dehydrogenase-phgdh/1174268
*  KAKEN - Research Projects | Functional analysis of mouse 3-phosphoglycerate dehydrogenase (Phgdh) gene by using gene targeting ...
D-3-Phosphoglycerate dehydrogenase (Phgdh ; EC 1.1.1.95) is the first committed enzyme of L-serine biosynthesis in the ... Publications] Yoshida, K., furuya, S., Osuka, S.et al.: 'Targeted disruption of the mouse3-phosphoglycerate dehydrogenase gene ... Publications] Shimizu, M., Furuya, S., Shinoda, Y.et al.: 'Functional analysis of mouse3-phosphoglycerate dehydrogenase(Phgdh) ... Functional analysis of mouse 3-phosphoglycerate dehydrogenase (Phgdh) gene by using gene targeting. Research Project ...
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-14580756/
*  3-Phosphoglycerate Dehydrogenase Deficiency - NxGen MDx
3-phosphoglycerate dehydrogenase deficiency prevents the body from synthesizing the amino acid serine, causing serious ... Carriers of 3-phosphoglycerate dehydrogenase deficiency have a single variant in one copy of the PHGDH gene while individuals ... 3-phosphoglycerate dehydrogenase deficiency is an autosomal recessive disorder caused by pathogenic variants in the PHGDH gene ... 3-phosphoglycerate dehydrogenase deficiency is an inherited condition that prevents the body from synthesizing the amino acid ...
https://nxgenmdx.com/disease/3-phosphoglycerate-dehydrogenase-deficiency/
*  Ser3p (Yer081wp) and Ser33p (Yil074cp) are phosphoglycerate dehydrogenases in Saccharomyces cerevisiae
... which encode phosphoglycerate dehydrogenases in Saccharomyces cerevisiae were identified. These dehydrogenases catalyze the ... Moreover, since phosphoglycerate dehydrogenase activity requires NAD+ as cofactor, deletion of SER3 and SER33 markedly affected ... Unlike either single mutant, the ser3Delta ser33Delta double mutant lacks detectable phosphoglycerate dehydrogenase activity ... However, the requirement for the SER-dependent 'phosphoglycerate pathway' is conditional since the 'glyoxylate' route of serine ...
https://research.chalmers.se/publication/73454
*  PHGDH gene - Genetics Home Reference
OMIM: PHOSPHOGLYCERATE DEHYDROGENASE. *. Tabatabaie L, de Koning TJ, Geboers AJ, van den Berg IE, Berger R, Klomp LW. Novel ... phosphoglycerate dehydrogenase. Enable Javascript to view the expand/collapse boxes.. Printable PDF Open All Close All ... At least eight mutations in the PHGDH gene have been found to cause phosphoglycerate dehydrogenase deficiency. This condition ... The PHGDH gene provides instructions for making the parts (subunits) that make up the phosphoglycerate dehydrogenase enzyme. ...
https://ghr.nlm.nih.gov/gene/PHGDH
*  Hybrid 3′ untranslated regions suitable for efficient protein expression in mammalian cells - King Faisal Specialist Hospital &...
Phosphoglycerate dehydrogenase. PHGDH. 231. 1340. NM_002796. Proteasome (prosome, macropain) subunit, beta type, 4. PSMB4. 108 ... Hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A. HADHA. 647. 1379. thiolase/enoyl-Coenzyme A hydratase ( ... glyceraldehyde 3-phosphate dehydrogenase (GAPDH), growth hormone, eukaryotic translation elongation factor 1 alpha 1 (EEF1A1), ...
http://www.freepatentsonline.com/9017965.html
*  JCI - ADHFE1 is a breast cancer oncogene and induces metabolic reprogramming
IDH, isocitrate dehydrogenase; PHGDH, phosphoglycerate dehydrogenase. (. C. ) High ADHFE1 protein expression by ... alcohol dehydrogenase, iron-containing protein 1 (ADHFE1), is a breast cancer oncogene that decreases patient survival. We ... but not with isocitrate dehydrogenase (IDH) mutations, suggesting a distinct mechanism for increased 2HG in breast cancer. Here ...
https://www.jci.org/articles/view/93815/figure/1
*  Albers E, et al. (2003) | SGD
... which encode phosphoglycerate dehydrogenases in Saccharomyces cerevisiae were identified. These dehydrogenases catalyze the ... Moreover, since phosphoglycerate dehydrogenase activity requires NAD(+) as cofactor, deletion of SER3 and SER33 markedly ... 2003) Ser3p (Yer081wp) and Ser33p (Yil074cp) are phosphoglycerate dehydrogenases in Saccharomyces cerevisiae. J Biol Chem 278( ... Unlike either single mutant, the ser3Delta ser33Delta double mutant lacks detectable phosphoglycerate dehydrogenase activity ...
https://www.yeastgenome.org/reference/12525494
*  451910: Inheritest® Gene-specific Sequencing, NGS | LabCorp
Phosphoglycerate dehydrogenase deficiency; Polycystic kidney disease, autosomal recessive; Pompe disease; Primary hyperoxaluria ... Phosphoglycerate dehydrogenase deficiency; Polycystic kidney disease, autosomal recessive; Pompe disease; Primary hyperoxaluria ... Phosphoglycerate dehydrogenase deficiency; Polycystic kidney disease, autosomal recessive; Pompe disease; Primary hyperoxaluria ... Dihydrolipoamide dehydrogenase deficiency; Dihydropyrimidine dehydrogenase deficiency; Ehlers-Danlos syndrome type VIIC; ...
https://www.labcorp.com/test-menu/29581/inheritest%C2%AE-gene-specific-sequencing-ngs